keyword
MENU ▼
Read by QxMD icon Read
search

signify study

keyword
https://www.readbyqxmd.com/read/29135939/bioactive-molecules-release-and-cellular-responses-of-alginate-tricalcium-phosphate-particles-hybrid-gel
#1
Dipankar Das, Sumi Bang, Shengmin Zhang, Insup Noh
In this article, a hybrid gel has been developed using sodium alginate (Alg) and α-tricalcium phosphate (α-TCP) particles through ionic crosslinking process for the application in bone tissue engineering. The effects of pH and composition of the gel on osteoblast cells (MC3T3) response and bioactive molecules release have been evaluated. At first, a slurry of Alg and α-TCP has been prepared using an ultrasonicator for the homogeneous distribution of α-TCP particles in the Alg network and to achieve adequate interfacial interaction between them...
November 14, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29133405/parallel-magnetic-field-suppresses-dissipation-in-superconducting-nanostrips
#2
Yong-Lei Wang, Andreas Glatz, Gregory J Kimmel, Igor S Aranson, Laxman R Thoutam, Zhi-Li Xiao, Golibjon R Berdiyorov, François M Peeters, George W Crabtree, Wai-Kwong Kwok
The motion of Abrikosov vortices in type-II superconductors results in a finite resistance in the presence of an applied electric current. Elimination or reduction of the resistance via immobilization of vortices is the "holy grail" of superconductivity research. Common wisdom dictates that an increase in the magnetic field escalates the loss of energy since the number of vortices increases. Here we show that this is no longer true if the magnetic field and the current are applied parallel to each other. Our experimental studies on the resistive behavior of a superconducting Mo0...
November 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29132946/an-interview-study-of-patient-and-caregiver-perspectives-on-advance-care-planning-in-esrd
#3
Marcus Sellars, Josephine M Clayton, Rachael L Morton, Tim Luckett, William Silvester, Lucy Spencer, Carol A Pollock, Rowan G Walker, Peter G Kerr, Allison Tong
BACKGROUND: Advance care planning (ACP) empowers patients to consider and communicate their current and future treatment goals. However, it can be an emotionally charged process for patients with kidney disease and their caregivers. This study aimed to describe the perspectives and attitudes of patients with end-stage renal disease (ESRD) and their caregivers toward ACP. STUDY DESIGN: Qualitative study. SETTING & PARTICIPANTS: Patients with ESRD (n=24) and their caregivers (n=15) aged 36 to 91 years at various stages of ACP ("not commenced," "in progress," or "completed") from 3 renal services...
November 10, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29130521/a-variant-in-ppp4r3a-protects-against-alzheimer-related-metabolic-decline
#4
Leigh Christopher, Valerio Napolioni, Raiyan R Khan, Summer S Han, Michael D Greicius
OBJECTIVES: A reduction in glucose metabolism in the posterior cingulate cortex (PCC) predicts conversion to Alzheimer's disease (AD) and tracks disease progression, signifying its importance in AD. We aimed to use decline in PCC glucose metabolism as a proxy for the development and progression of AD to discover common genetic variants associated with disease vulnerability. METHODS: We performed a genome-wide association study (GWAS) of decline in PCC [(18) F] FDG PET measured in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants (n=606)...
November 11, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29129777/trichloroethylene-metabolite-s-1-2-dichlorovinyl-l-cysteine-induces-lipid-peroxidation-associated-apoptosis-via-the-intrinsic-and-extrinsic-apoptosis-pathways-in-a-first-trimester-placental-cell-line
#5
Elana R Elkin, Sean M Harris, Rita Loch-Caruso
Trichloroethylene (TCE), a prevalent environmental contaminant, is a potent renal and hepatic toxicant through metabolites such as S-(1, 2-dichlorovinyl)-l-cysteine (DCVC). However, effects of TCE on other target organs such as the placenta have been minimally explored. Because elevated apoptosis and lipid peroxidation in placenta have been observed in pregnancy morbidities involving poor placentation, we evaluated the effects of DCVC exposure on apoptosis and lipid peroxidation in a human extravillous trophoblast cell line, HTR-8/SVneo...
November 9, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29128935/associations-between-birthweight-gestational-age-at-birth-and-subsequent-type-1-diabetes-in-children-under-12-a-retrospective-cohort-study-in-england-1998-2012
#6
Raphael R Goldacre
AIMS/HYPOTHESIS: With genetics thought to explain only 40-50% of the total risk of type 1 diabetes, environmental risk factors in early life have been proposed. Previous findings from studies of type 1 diabetes incidence by birthweight and gestational age at birth have been inconsistent. This study aimed to investigate the relationships between birthweight, gestational age at birth and subsequent type 1 diabetes in England. METHODS: Data were obtained from a population-based database comprising linked mother-infant pairs using English national Hospital Episode Statistics from 1998 to 2012...
November 11, 2017: Diabetologia
https://www.readbyqxmd.com/read/29127539/biotreatment-of-effluent-from-adire-textile-factories-in-ibadan-nigeria
#7
Oladapo T Okareh, Tuntunlade F Ademodi, Etinosa O Igbinosa
In this present study, bacteria were isolated from wastewater and polluted soil collected from two cottage textile factories in Ibadan. These bacteria isolates were used for the biotreatment of textile mill effluent. The physicochemical parameters of the textile mill effluent before treatment were carried out and percentage decolourisation of the effluent was analysed using ultraviolet-visible spectroscopy (UV-vis technique). The degradation products of the textile mill effluent characterised by Fourier transform infrared spectroscopy (FTIR)...
November 10, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29121243/a-structured-training-program-for-minimally-invasive-esophagectomy-for-esophageal-cancer-a-delphi-consensus-study-in-europe
#8
E Visser, P S N van Rossum, H van Veer, K Al-Naimi, M A Chaudry, M A Cuesta, S S Gisbertz, C A Gutschow, A H Hölscher, M D P Luyer, C Mariette, K Moorthy, G A P Nieuwenhuijzen, M Nilsson, J V Räsänen, P M Schneider, W Schröder, E Cheong, R van Hillegersberg
Evidence suggests that structured training programs for laparoscopic procedures can ensure a safe standard of skill acquisition prior to independent practice. Although minimally invasive esophagectomy (MIO) is technically demanding, no consensus on requirements for training for the MIO procedure exists. The aim of this study is to determine essential steps required for a structured training program in MIO using the Delphi consensus methodology. Eighteen MIO experts from 13 European hospitals were asked to participate in this study...
November 7, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29120134/bone-mineral-density-in-relation-to-metabolic-syndrome-components-in-postmenopausal-women-with-diabetes-mellitus-type-2
#9
Ines Bilić-Ćurčić, Sandra Makarović, Ivan Mihaljević, Maja Franceschi, Tomislav Jukić
Diabetes mellitus type 2 is associated with greater bone mineral density (BMD) due to obesity, although rapid bone loss observed over time could be explained by elevated chronic inflammation. The objective of this study was to investigate the relationship between central adiposity and hyperinsulinemia, as well as inflammation markers with vertebral and femoral BMD and bone turnover markers in postmenopausal women with type 2 diabetes. Femoral and vertebral BMD, osteocalcin, pyrilinks D, beta-CrossLaps (B-CTx), insulin, C-reactive protein (CRP), fibrinogen and plasminogen activator inhibitor-1 (PAI-1) were measured in 114 postmenopausal female patients with diabetes type 2...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29116579/gene-encoding-vesicle-associated-membrane-protein-associated-protein-from-triticum-aestivum-tavap-confers-tolerance-to-drought-stress
#10
Brinderjit Singh, Paramjit Khurana, Jitendra P Khurana, Prabhjeet Singh
Abiotic stresses like drought, salinity, high and low temperature, and submergence are major factors that limit the crop productivity. Hence, identification of genes associated with stress response in crops is a prerequisite for improving their tolerance to adverse environmental conditions. In an earlier study, we had identified a drought-inducible gene, vesicle-associated membrane protein-associated protein (TaVAP), in developing grains of wheat. In this study, we demonstrate that TaVAP is able to complement yeast and Arabidopsis mutants, which are impaired in their respective orthologs, signifying functional conservation...
November 7, 2017: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/29115210/surgeon-performed-ultrasonography
#11
Tobias Todsen
Surgeons are increasingly using ultrasonography (US) in their clinical management of patients. However, US is a very user-dependent imaging modality and proper skills of the US operator are needed to ensure quality in patient care. This thesis explores the validity evidence for assessment of competence in abdominal and head & neck ultrasonography using the Objective Structured Assessment of Ultrasound Skills (OSAUS) scale. With the use of Messick's unitary framework of validity, five sources of validity evidence were explored: test content, response processes, inter-nal structure, relations to other variables, and consequences...
November 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/29108892/antifungal-activity-of-latarcin-1-derived-cell-penetrating-peptides-against-fusarium-solani
#12
Deepthi Poornima Budagavi, Sheeba Zarin, Archana Chugh
Cell-penetrating peptides and antimicrobial peptides share physicochemical characteristics and mechanisms of interaction with biological membranes, hence, termed as membrane active peptides. The present study aims at evaluating AMP activity of CPPs. LDP-NLS and LDP are Latarcin 1 derived cell-penetrating peptides and in the current study we have evaluated antifungal and cell-penetrating properties of these CPPs in Fusarium solani. We observed that LDP-NLS and LDP exhibited excellent antifungal activity against the fungus...
November 3, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29107082/purification-and-characterization-of-an-anti-hemorrhagic-protein-from-naja-naja-indian-cobra-venom
#13
K N Suvilesh, M Yariswamy, M N Savitha, Vikram Joshi, A N Nanjaraj Urs, Amog P Urs, M Choudhury, D Velmurugan, B S Vishwanath
Snake venom Kunitz-type proteins are well known to inhibit serine proteases but a few studies have also shown matrix metalloproteases (MMPs) inhibition. In view of the fact that MMPs and snake venom metalloproteases (SVMPs) have similar catalytic site, inhibition of SVMP activity by Kunitz-type proteins remains to be studied. Recent proteomic studies of Naja naja (N. naja) venom revealed the abundance of Kunitz-type proteins. In this regard, present study aimed at purification of a protease inhibitor from N...
October 26, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29104222/practical-synthesis-of-chalcone-derivatives-and-their-biological-activities
#14
Jae-Chul Jung, Yongnam Lee, Dongguk Min, Mankil Jung, Seikwan Oh
Practical synthesis and biological activities of 4-hydroxy-3-methoxy-2-propene derivatives are described. The novel chalcone derivatives were prepared by acid catalysed one-step condensation of 1,3- or 1,4-diacetylbenzene and 1,3,5-triacetylbenzene with 4-hydroxy-3-methoxybenzaldehyde. They were then evaluated for free radical scavenging activity, suppression of lipopolysaccharides (LPS)-induced NO generation, and anti-excitotoxicity in vitro. It was found that all compounds showed good effects for 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, LPS-induced NO generation, and anti-neurotoxicity...
November 1, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29101722/updates-and-critical-insights-on-glissonian-approach-in-liver-surgery
#15
Demetrios Moris, Amir A Rahnemai-Azar, Diamantis I Tsilimigras, Ioannis Ntanasis-Stathopoulos, Hugo P Marques, Eleftherios Spartalis, Evangelos Felekouras, Timothy M Pawlik
Recent advances in surgical techniques have broadened the indications of surgical management of liver malignancies. Intraoperative bleeding is one of the known predictors of postoperative outcomes following liver surgery, signifying the importance of vascular control during liver resection. Furthermore, preservation of future liver remnant plays a critical role in prevention of post-hepatectomy liver failure as one of the main causes of postoperative morbidity and mortality. Glissonian approach liver resection offers an effective method for vascular inflow control while protecting future liver remnant from ischemia-reperfusion injury...
November 3, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29100836/changes-in-tricuspid-annular-geometry-in-patients-with-functional-tricuspid-regurgitation
#16
Ting Hai, Yannis Amador, Feroze Mahmood, Jelliffe Jeganathan, Arash Khamooshian, Ziyad O Knio, Robina Matyal, Alina Nicoara, David C Liu, Venkatachalam Senthilnathan, Kamal R Khabbaz
OBJECTIVE: To determine whether the indices of tricuspid annular dynamics that signify irreversible tricuspid valvular remodeling can improve surgical decision making by helping to better identify patients with functional tricuspid regurgitation who could benefit from annuloplasty. DESIGN: Retrospective analysis study. SETTING: Tertiary hospital. PARTICIPANTS: A total number of 55 patients were selected, 18 with functional tricuspid valve (TV) regurgitation and 37 normal nonregurgitant TVs...
June 20, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29097858/serum-cortisol-level-in-indian-patients-with-severe-sepsis-septic-shock
#17
Ragavendra Suresh, Naveet Wig, Prasan Kumar Panda, V P Jyotsna, P K Chaturvedi, R M Pandey
Background: The relationship between cortisol level and sepsis is not known in Indian patients of severe sepsis/septic shock. Aims: The study was done to determine the optimal range of cortisol levels, defining the adrenocortical response, and predicting the mortality, if possible, in the above type of patients. Settings and Designs: The study was a single-centered prospective cohort study, conducted in a tertiary referral center, North India...
October 2017: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29096153/uptake-and-speciation-of-uranium-in-synthetic-gypsum-caso4%C3%A2-2h2o-applications-to-radioactive-mine-tailings
#18
Jinru Lin, Wei Sun, Jacques Desmarais, Ning Chen, Renfei Feng, Patrick Zhang, Dien Li, Arthur Lieu, John S Tse, Yuanming Pan
Phosphogypsum formed from the production of phosphoric acid represents by far the biggest accumulation of gypsum-rich wastes in the world and commonly contains elevated radionuclides, including uranium, as well as other heavy metals and metalloids. Therefore, billions-of-tons of phosphogypsum stockpiled worldwide not only possess serious environmental problems but also represent a potential uranium resource. Gypsum is also a major solid constituent in many other types of radioactive mine tailings, which stems from the common usage of sulfuric acid in extraction processes...
October 26, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29091109/surface-thermal-and-hemocompatible-properties-of-novel-single-stage-electrospun-nanocomposites-comprising-polyurethane-blended-with-bio-oiltm
#19
Manikandan Ayyar, Mohan Prasath Mani, Saravana Kumar Jaganathan, Rajasekar Rathinasamy, Ahmad Zahran Khudzari, Navaneetha Pandiyaraj Krishnasamy
In this work, the physicochemical and blood compatibility properties of prepared PU/Bio oil nanocomposites were investigated. Scanning electron microscope (SEM) studies revealed the reduction of mean fiber diameter (709 ± 211 nm) compared to the pristine PU (969 nm ± 217 nm). Fourier transform infrared spectroscopy (FTIR) analysis exposed the characteristic peaks of pristine PU. Composite peak intensities were decreased insinuating the interaction of the bio oilTM with the PU. Contact angle analysis portrayed the hydrophobic nature of the fabricated patch compared to pristine PU...
October 26, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29080780/projecting-the-impact-of-anal-intercourse-on-hiv-transmission-among-heterosexuals-in-high-hiv-prevalence-settings
#20
Noble J Malunguza, Senelani D Hove-Musekwa, Zindoga Mukandavire
Whereas penile vaginal intercourse (VI) is thought to be the dominant mode of HIV transmission in sub-Saharan Africa, cross-sectional studies in the region indicate the preponderance of heterosexual anal intercourse (AI) among high activity groups. A dynamic, heterosexual core group model with risk of infection through both vaginal and anal pathways is formulated and comprehensively analysed. The model is coupled to a general population model and fitted to HIV prevalence data for Zimbabwe in order to explore the parameter space related to heterosexual AI...
November 1, 2017: Journal of Theoretical Biology
keyword
keyword
60669
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"