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cetirizine children

Jeff Aston, Natasha Patel, Justin Smuels, Teena Aujla, Georgia Malesi, Chi Huynh, Keith Wilson, David Terry
AIM: To identify what medicines related information children/young people or their parents/carers are able to recall following an out-patient clinic appointment. METHOD: A convenience sample of patients' prescribed at least one new long-term (>6 weeks) medicine were recruited from a single UK paediatric hospital out-patient pharmacy.A face-to-face semi-structured questionnaire was administered to participants when they presented with their prescription. The questionnaire included the following themes: names of the medicines, therapeutic indication, dose regimen, duration of treatment and adverse effects...
September 2016: Archives of Disease in Childhood
Laura Isabell Immohr, Claas Hedfeld, Artur Lang, Miriam Pein-Hackelbusch
Manipulation of liquid oral drugs by mixing them into foodstuff is a common procedure for taste-masking of OTC pharmaceuticals when administered to children. However, the taste-masking capability of such application media is not systematically evaluated, and recommendations for suitable media are hardly published. In this study, a sensor array of commercially available and self-developed electronic tongue sensors was employed to assess the taste-masking efficiency of eight different beverages (tap water, apple juice, carrot juice, fennel tea, fruit tea, milk, cocoa, and Alete meal to drink) on the OTC pharmaceuticals Ambroxol-ratiopharm®, Cetirizin AL, and Laxoberal® by multivariate data analysis...
April 13, 2016: AAPS PharmSciTech
Xin Hui Magdeline Lee, Lin Xin Ong, Jing Yi Vanessa Cheong, Rehena Sultana, Rajeshwar Rao, Hwee Hoon Lim, Xiao Mei Ding, Wen Yin Loh, Monika Punan, Wen Chin Chiang
BACKGROUND: There is limited literature in the management of chronic urticaria in children. Treatment algorithms are generally extrapolated from adult studies. OBJECTIVE: Utility of a weight and age-based algorithm for antihistamines in management of chronic spontaneous urticaria (CSU) in childhood. To document associated factors that predict for step of control of CSU and time taken to attain control of symptoms in children. METHODS: A workgroup comprising of allergists, nurses, and pharmacists convened to develop a stepwise treatment algorithm in management of children with CSU...
January 2016: Asia Pacific Allergy
M Sánchez-Borges, A Capriles-Hulett, F Caballero-Fonseca
BACKGROUND: Urticaria is a common cause for consultation in general and specialised medical practices. There is scarce information on the characteristics of patients suffering acute urticaria in Latin America. OBJECTIVES: To investigate demographic and clinical features of patients with acute urticaria attending two allergy clinics in Caracas, Venezuela. METHODS: A prospective study of all new patients who consulted during a three-year period because of acute urticaria...
July 2015: Allergologia et Immunopathologia
Daniele Piovani, Antonio Clavenna, Maurizio Bonati
AIM: Most Italian children are cared for by a family paediatrician until they are 14 years old, and their duties include prescribing drugs recommended by specialists so that they are free. This study aimed to draw up a list of the drugs most commonly prescribed by family paediatricians. METHODS: We surveyed 64 experienced family paediatricians to find out what drugs they prescribed over an 8-week period, including those recommended by a specialist, using cartons of drugs as the unit of measurement...
December 2014: Acta Paediatrica
Michele Miraglia Del Giudice, Nunzia Maiello, Carlo Capristo, Emilia Alterio, Michele Capasso, Laura Perrone, Giorgio Ciprandi
OBJECTIVE: Allergic rhinitis (AR) is caused by an IgE-mediated inflammatory reaction consequent to the exposure to causal allergen. Resveratrol is a natural non-flavonoid polyphenol, exerting anti-inflammatory activity; β-glucan is a polysaccharide with immuno-modulatory properties. Thus, this study aimed to investigate whether these combined compounds are able of relieving nasal symptoms in children with AR due to pollen allergy. RESEARCH DESIGN AND METHODS: The present study was conducted as placebo-controlled, double-blinded, and randomized...
October 2014: Current Medical Research and Opinion
Agnieszka Biedroł, Marek Kaciłski, Barbara Skowronek-Bała
The occurrence of stabbing headaches in children requires a thorough diagnostic approach that excludes secondary headaches. The organic background should be taken into consideration when alarming symptoms occur, such as a purely 1-sided location, a change in the character of the headache, or possibly a link to physical activity. The current study describes the case of an 8-year-old girl who suffered short-lasting stabbing headache attacks. The headaches with increasing intensity and frequency started 1 month before her hospitalization and were usually preceded by physical activity (dancing, running)...
April 2014: Pediatrics
Samir M Al-Minshawy, Abdel-Azeem M El-Mazary
INTRODUCTION: Erythromelalgia is a rare clinical syndrome characterized by episodic erythema, warmth and intense burning pain, which commonly involves the extremities. For those affected, this disorder may lead to significant long-term morbidity. Unfortunately, to date, no definitive therapy is available. This case report describes an Egyptian child with primary erythromelalgia that manifested at an early age and showed partial response to therapy with cetirizine hydrochloride. This anecdotal case report may have a diagnostic value for clinicians who have not seen this disorder...
2014: Journal of Medical Case Reports
Carmen Ferrajolo, Preciosa M Coloma, Katia M C Verhamme, Martijn J Schuemie, Sandra de Bie, Rosa Gini, Ron Herings, Giampiero Mazzaglia, Gino Picelli, Carlo Giaquinto, Lorenza Scotti, Paul Avillach, Lars Pedersen, Francesco Rossi, Annalisa Capuano, Johan van der Lei, Gianluca Trifiró, Miriam C J M Sturkenboom
BACKGROUND: Data mining in spontaneous reporting databases has shown that drug-induced liver injury is infrequently reported in children. OBJECTIVES: Our objectives were to (i) identify drugs potentially associated with acute liver injury (ALI) in children and adolescents using electronic healthcare record (EHR) data; and (ii) to evaluate the significance and novelty of these associations. METHODS: We identified potential cases of ALI during exposure to any prescribed/dispensed drug for individuals <18 years old from the EU-ADR network, which includes seven databases from three countries, covering the years 1996-2010...
February 2014: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
Cigdem Kalaycik Ertugay, Cemal Cingi, Aytekin Yaz, Turhan San, Seckin Ulusoy, Nagehan Erdogmus, Omer Cagatay Ertugay
CONCLUSION: This study demonstrated that treatment with montelukast in combination with levocetirizine may have a beneficial effect on clinical improvement of middle ear fluid in children with otitis media with effusion (OME). OBJECTIVE: To evaluate the effect of the combination of montelukast and levocetirizine on shortening the duration of effusion in successfully treated OME in children. METHODS: This was a randomized, prospective, double-blind, placebo-controlled trial...
December 2013: Acta Oto-laryngologica
Tom Marrs, Katherine Anagnostou, Roisin Fitzsimons, Adam T Fox
Acute and chronic symptoms of allergic rhinitis (AR) can disrupt school and leisure activities, significantly reducing quality of life. Symptoms often impair sleep, resulting in tiredness and poor concentration. Children with seasonal AR perform significantly worse in summer exams, relative to their mock exam results, when compared with their peers. Those individuals showing most symptoms are also likely to be affected by other allergic diseases, magnifying the detrimental impact on quality of life. Nasal blockage is the most common complaint associated with chronic AR, with acute exacerbations causing sneezing, clear nasal discharge and itchy eyes following exposure to the relevant airborne triggers...
June 2013: Practitioner
Ko-Haung Lue, Hai-Lun Sun, Ko-Hsiu Lu, Min-Sho Ku, Ji-Nan Sheu, Ching-Hui Chan, Yun-Hu Wang
BACKGROUND: Supplementary consumption of probiotics may temporarily alter the intestinal microflora of infants and children, thereby preventing and treating allergic disorders. OBJECTIVE: To compare the clinical efficacy of levocetirizine with that of levocetirizine plus Lactobacillus johnsonii EM1 (Lj EM1) for treating perennial allergic rhinitis (PAR) in children. METHODS: Sixty-three children aged 7-12 years fulfilled the entry criteria for the study and had moderate to severe PAR of at least 1 year's duration...
July 2012: International Journal of Pediatric Otorhinolaryngology
Jean Bousquet, Ignacio Ansótegui, G Walter Canonica, Torsten Zuberbier, Carlos E Baena-Cagnani, Claus Bachert, Alvaro A Cruz, Sandra N González, Piotr Kuna, Mario Morais-Almeida, Joaquim Mullol, Dermot P Ryan, Mario Sánchez-Borges, Román Valiente, Martin K Church
BACKGROUND: The ARIA (Allergic Rhinitis and its Impact on Asthma) guidelines development group examined the properties of oral H(1)-antihistamines and made proposals about an 'optimal' drug. Several criteria should be met by oral H(1)-antihistamines in terms of their pharmacological, and clinical efficacy and safety profiles. OBJECTIVE: Bilastine, a new H(1)-antihistamine, has been approved in 28 European countries for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria in adults and children older than 12 years...
January 2012: Current Medical Research and Opinion
B Sádaba Díaz de Rada, J R Azanza Perea, A Gomez-Guiu Hormigos
Bilastine is a potent inhibitor of the histamine H1 receptor. It was recently approved in 28 countries of the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria in adults and children older than 12 years. Data from preclinical studies confirmed its selectivity for the histamine H1 receptor over other receptors, and demonstrated antihistaminic and antiallergic properties in vivo. Studies in healthy volunteers and patients have shown that bilastine does not affect driving ability, cardiac conduction or alertness...
April 2011: Drugs of Today
A Pierchalla, D Bruch-Gerharz, B Homey, J Reifenberger
Linear IgA bullous dermatosis is an acquired autoimmune subepidermal blistering disease, characterized by linear IgA deposits at the basement membrane zone. Described in both children and adults, it occurs as tense pruritic vesicles and bullae in a "cluster of jewels" configuration with central crusting on an inflammatory elevated base. It is typically located on the face, anogenital region and trunk. Whilst the adult manifestations can be chronic, in children a spontaneous remission has often been reported...
April 2011: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
A N Pampura, N G Papadopoulos, V Spičák, R Kurzawa
Allergic rhinitis (AR) and chronic idiopathic urticaria (CIU) are highly burdensome diseases, which are increasing in prevalence, especially in the paediatric population. Despite the availability of a large number of medications for treatment of AR and CIU, their use in children has primarily been based on data obtained from a limited number of clinical trials in children and/or testing in adults. The H(1)-antihistamines have traditionally been used as first-line treatment for the relief of both AR and CIU symptoms in children...
2011: International Archives of Allergy and Immunology
M Marogna, A Massolo, F Colombo, P Isella, M Bruno, P Falagiani
BACKGROUND: The association between genetic predisposition and environmental risk factors such as passive smoke in determining respiratory allergies is still uncertain; even less is known about the role played by passive smoking in influencing the success of therapy for rhinitis and allergic asthma. OBJECTIVE: The purpose of this prospective, randomised study was to determine whether passive smoking influences the outcome of therapies in paediatric patients with allergic respiratory diseases...
March 2011: Allergologia et Immunopathologia
Francesco Marcucci, Laura Giovanna Sensi, Piera Abate, Giusiana Allocca, Eleonora Ugolini, Giuseppe Di Cara, Cristoforo Incorvaia
The non-sedating third generation antihistamine levocetirizine has ample evidence of efficacy in allergic rhinitis. In vitro studies suggested that levocetirizine has anti-inflammatory properties not simply related to the antihistamine activity but also to regulation of eosinophils. We performed a double-blind placebo-controlled study in 40 children allergic to house dust mites with persistent rhinitis with the primary aim to evaluate the anti-inflammatory efficacy of levocetirizine measuring eosinophil-related parameters and exhaled nitric oxide (eNO)...
February 2011: Inflammation & Allergy Drug Targets
Frank Hampel, Paul Ratner, Jean-Marc C Haeusler
Allergic rhinitis (AR) and chronic idiopathic urticaria (CIU) are common causes of substantial illness and disability in preschool children. Antihistamines are commonly used to treat preschool children with these conditions, but their use is based mostly on extrapolated efficacy from adult populations; it is thus important to characterize the safety of antihistamines in the pediatric population. This study was designed to assess the safety of levocetirizine dihydrochloride oral liquid drops in infants and children with AR or CIU...
July 2010: Allergy and Asthma Proceedings:
P Lahdenne, A M Wikström, K Aalto, K L Kolho
OBJECTIVE: To study whether premedication with an oral antifebrile agent (acetaminophen) and antihistamine (cetirizine) could decrease the frequency of acute infusion reactions in pediatric patients. METHODS: All pediatric patients scheduled for infliximab infusions at the Helsinki University Central Hospital, a tertiary care center, were prospectively introduced to a standard oral premedication of acetaminophen (20 mg/kg) and cetirizine (10 mg) prior to infliximab infusions for a period of 1 year...
June 2010: Arthritis Care & Research
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