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https://www.readbyqxmd.com/read/28226837/a-preliminary-evaluation-of-myoelectrical-energy-distribution-of-the-front-neck-muscles-in-pharyngeal-phase-during-normal-swallowing
#1
Mingxing Zhu, Wanzhang Yang, Oluwarotimi Williams Samuel, Yun Xiang, Jianping Huang, Haiqing Zou, Guanglin Li, Mingxing Zhu, Wanzhang Yang, Oluwarotimi Williams Samuel, Yun Xiang, Jianping Huang, Haiqing Zou, Guanglin Li, Wanzhang Yang, Yun Xiang, Guanglin Li, Haiqing Zou, Jianping Huang, Oluwarotimi Williams Samuel, Mingxing Zhu
Pharyngeal phase is a central hub of swallowing in which food bolus pass through from the oral cavity to the esophageal. Proper understanding of the muscular activities in the pharyngeal phase is useful for assessing swallowing function and the occurrence of dysphagia in humans. In this study, high-density (HD) surface electromyography (sEMG) was used to study the muscular activities in the pharyngeal phase during swallowing tasks involving three healthy male subjects. The root mean square (RMS) of the HD sEMG data was computed by using a series of segmented windows as myoelectrical energy...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226760/a-new-approach-of-oral-cancer-detection-using-bilateral-texture-features-in-digital-infrared-thermal-images
#2
M Chakraborty, S Mukhopadhyay, A Dasgupta, S Patsa, N Anjum, J G Ray, M Chakraborty, S Mukhopadhyay, A Dasgupta, S Patsa, N Anjum, J G Ray, S Patsa, A Dasgupta, N Anjum, M Chakraborty, S Mukhopadhyay, J G Ray
Oral cancer is one of the most prevalent form of cancer and its severity is aggrandized specially among the socio-economically backward population in developing countries. A major fraction of patient population is unable to avail diagnosis for oral cancer due to scarcity of state-of-the-art infrastructure and experienced oral and maxillofacial pathologist. Contemporary gold standard of oral cancer confirmation relies on biopsy report. But biopsy is invasive and thus patients are usually reluctant to undergo this test...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226319/oral-and-sublingual-immunotherapy-potential-causes-for-eosinophilic-gastrointestinal-disorders
#3
Delara Babaie, Mehrnaz Mesdaghi, Makoto Nishino, Mahboubeh Mansouri, Motohiro Ebisawa
Food allergy is a common health problem worldwide, with increasing prevalence during recent decades. The only approved treatments for food allergy are food avoidance and administration of emergency medications in case of accidental exposure, which negatively affects patients' quality of life, so new treatments are highly desirable. Different food immunotherapy modalities have recently been used, with variable success rates in the induction of desensitization and tolerance, and different numbers and types of adverse reactions...
February 23, 2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/28225505/nonrevascularizable-buttock-claudication-improved-with-sildenafil-a-case-report
#4
Loukman Omarjee, Audrey Camarzana, Samir Henni, Pierre Abraham
RATIONALE: Sildenafil, a phosphodiesterase-5-inhibitor (PDE5i), could represent a new treatment in addition to the medical treatment and advice to walk in peripheral arterial disease (PAD). PATIENT CONCERNS AND DIAGNOSES: We report a case of a 62-year-old heavy smoker man who developed a buttock claudication and a severe walking limitation following an aorto-bi-femoral bypass in 1992. Since 2003, each year, he has been referred for investigation of bilateral buttock claudication on treadmill using transcutaneous oxygen pressure (tcpO2) measurement during exercise to argue for the vascular origin of the walking impairment...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28224613/gli3-related-polydactyly-a-review
#5
REVIEW
M M Al-Qattan, H E Shamseldin, M A Salih, F S Alkuraya
GLI3 mutations are known to be associated with nine syndromes/conditions in which polydactyly is a feature. In this review, the embryology, pathogenesis, and animal models of GLI3-related polydactyly are discussed first. This is followed by a detailed review of the genotype-phenotype correlations. Based on our review of the literature and our clinical experiences, we recommend viewing GLI3-related syndromes/conditions as four separate entities; each characterized by a specific pattern of polydactyly. These four entities are: the preaxial polydactyly type IV-Greig-acrocallosal spectrum, postaxial polydactyly types A/B, Pallister-Hall syndrome (PHS), and oral-facial-digital overlap syndrome...
February 22, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/28224352/hcv-management-in-resource-constrained-countries
#6
REVIEW
Seng Gee Lim
With the arrival of all-oral directly acting antiviral (DAA) therapy with high cure rates, the promise of hepatitis C virus (HCV) eradication is within closer reach. The availability of generic DAAs has improved access to countries with constrained resources. However, therapy is only one component of the HCV care continuum, which is the framework for HCV management from identifying patients to cure. The large number of undiagnosed HCV cases is the biggest concern, and strategies to address this are needed, as risk factor screening is suboptimal, detecting <20% of known cases...
February 21, 2017: Hepatology International
https://www.readbyqxmd.com/read/28223744/usefulness-of-dermoscopy-in-the-differential-diagnosis-of-ruptured-and-unruptured-epidermal-cysts
#7
Kee Suck Suh, Dong Young Kang, Jong Bin Park, Myeong Hyeon Yang, Joon Hee Kim, Kang Hoon Lee, Sang Hwa Han, Yun Deok Choi, Sang Tae Kim, Min Soo Jang
BACKGROUND: An epidermal cyst is a common keratin-filled epithelial-lined cyst. The treatment of choice for epidermal cysts is surgical excision. If the cyst becomes ruptured, incision and drainage with oral antibiotic therapy or intralesional steroid injection are required. OBJECTIVE: To analyze the dermoscopic features that can differentiate between ruptured and unruptured epidermal cysts. METHODS: The clinical and dermoscopic features of the pathologically confirmed epidermal cysts of two subgroups of 38 patients, 20 with unruptured cysts and 18 with ruptured cysts, were reviewed...
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28223139/the-role-of-il-1-gene-polymorphisms-il1a-il1b-and-il1rn-as-a-risk-factor-in-unsuccessful-implants-retaining-overdentures
#8
Margarida Sampaio Fernandes, Paula Vaz, Ana Cristina Braga, João Carlos Sampaio Fernandes, Maria Helena Figueiral
PURPOSE: Implant-supported overdentures are an alternative predictable rehabilitation method that has a high impact on improving the patient's quality of life. However, some biological complications may interfere with the maintenance and survival of these overdenture implants. The goal of this article was to assess the factors that affect peri-implant success, through a hypothetical prediction model for biological complications of implant overdentures. METHODS: A retrospective observational, prevalence study was conducted in 58 edentulous Caucasian patients rehabilitated with implant overdentures...
February 17, 2017: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/28222889/pre-cancer-risk-assessment-in-habitual-smokers-from-dic-images-of-oral-exfoliative-cells-using-active-contour-and-svm-analysis
#9
Susmita Dey, Ripon Sarkar, Kabita Chatterjee, Pallab Datta, Ananya Barui, Santi P Maity
Habitual smokers are known to be at higher risk for developing oral cancer, which is increasing at an alarming rate globally. Conventionally, oral cancer is associated with high mortality rates, although recent reports show the improved survival outcomes by early diagnosis of disease. An effective prediction system which will enable to identify the probability of cancer development amongst the habitual smokers, is thus expected to benefit sizable number of populations. Present work describes a non-invasive, integrated method for early detection of cellular abnormalities based on analysis of different cyto-morphological features of exfoliative oral epithelial cells...
February 9, 2017: Tissue & Cell
https://www.readbyqxmd.com/read/28222436/recurrent-angioedema-occurrence-features-and-concomitant-diseases-in-an-italian-single-center-study
#10
Paola Triggianese, Maria Domenica Guarino, Chiara Pellicano, Mauro Borzi, Elisabetta Greco, Stella Modica, Caterina De Carolis, Roberto Perricone
BACKGROUND: Angioedema (AE) is a potentially life-threatening condition with hereditary (HAE), acquired (AAE), or iatrogenic causes. A careful workup allows for the identification of the etiology of attacks and the appropriate management. In this cohort study, based on a clinical practice setting, we aimed at investigating clinical and laboratory findings concerning different features of patients with recurrent AE who were referred to a single, tertiary-level center for HAE. METHODS: Clinical and laboratory data of patients fulfilling the criteria for C1-inhibitor-deficient HAE (C1-INH-HAE), C1-INH-AAE, angiotensin-converting enzyme inhibitor-related AE (ACEI-RA), and idiopathic AAE (I-AAE) were evaluated...
February 22, 2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/28222034/three-cases-of-gordon-syndrome-with-dominant-klhl3-mutations
#11
Ji Soo Park, Eujin Park, Hye Sun Hyun, Yo Han Ahn, Hee Gyung Kang, Il-Soo Ha, Hae Il Cheong
BACKGROUND: Gordon syndrome (GS) is a rare form of monogenic hypertension characterized by low renin hypertension, hyperkalemia, hyperchloremic metabolic acidosis, and normal glomerular filtration rate. To date, four genes causing GS have been identified as: WNK1, WNK4, CUL3, and KLHL3. CASE REPORT: We report three cases of GS in two families. All patients presented with typical clinical features of GS and had a known dominant KLHL3 mutation. Oral thiazide treatment with low salt diet resulted in normalization of blood pressure and serum electrolytes in all three cases...
February 21, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28220360/oral-histoplasmosis
#12
Gillian A Folk, Brenda L Nelson
A 44-year-old female presented to her general dentist with the chief complaint of a painful mouth sore of 2 weeks duration. Clinical examination revealed an irregularly shaped ulcer of the buccal and lingual attached gingiva of the anterior mandible. A biopsy was performed and microscopic evaluation revealed histoplasmosis. Histoplasmosis, caused by Histoplasma capsulate, is the most common fungal infection in the United States. Oral lesions of histoplasmosis are generally associated with the disseminated form of histoplasmosis and may present as a fungating or ulcerative lesion of the oral mucosa...
February 20, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28220329/disproportional-increase-of-pulmonary-embolism-in-young-females-in-germany-trends-from-2005-to-2014
#13
F Santosa, Ch Moerchel, Ch Berg, K Kröger
We analysed the number of pulmonary embolism (PE) in young females aged 10-39 years in the period from 2005 to 2014 in Germany to see any trends that possibly may reflect some influences of newer oral contraceptives. Detailed lists of all hospitalized cases with the principal diagnosis PE coded as I26 in the years 2005-2014 were provided by the Federal Statistical Office. In males, the absolute number of all hospitalized cases with the principal diagnosis PE increased from 16,066 in 2005 to 25,364 in 2014 (rate +57...
February 20, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28219414/severe-skull-base-osteomyelitis-caused-by-pseudomonas-aeruginosa-with-successful-outcome-after-prolonged-outpatient-therapy-with-continuous-infusion-of-ceftazidime-and-oral-ciprofloxacin-a-case-report
#14
Cristina Conde-Díaz, Jara Llenas-García, Mónica Parra Grande, Gertrudis Terol Esclapez, Mar Masiá, Félix Gutiérrez
BACKGROUND: Skull base osteomyelitis is an uncommon disease that usually complicates a malignant external otitis with temporal bone involvement. It affects predominantly diabetic and immunocompromised males and has a high mortality rate. Pseudomonas aeruginosa is the most common causative organism. Currently, there is no consensus about the best therapeutic option. Here we describe a case of severe skull base osteomyelitis caused by Pseudomonas aeruginosa with progressive palsy of cranial nerves that was successfully managed with prolonged outpatient continuous infusion of ceftazidime plus oral ciprofloxacin...
February 21, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28219166/-the-value-of-sinonasal-ct-scan-in-diagnosing-of-eosinophilic-chronic-rhinosinusitis-with-nasal-polyps
#15
Y F Meng, H F Lou, C S Wang, L Zhang
Objective: To compare the value of sinonasal CT scan with other clinical parameters in the pre-diagnosis of eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP). Methods: From January to May of 2016, One hundred and fifty consecutive CRSwNP patients (90 eCRSwNP and 60 non-eosinophilic CRSwNP) undergoing endoscopic functional sinus surgery in Beijing Tongren Hospital were recruited in this study. Preoperative CT scan, skin prick test (SPT) and oral fractional exhaled nitric oxide (FeNO) measurements were performed in each patient and full blood count with differential analysis was performed within 1 week before surgery...
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28218707/fkbp51-immunohistochemical-expression-a-new-prognostic-biomarker-for-oscc
#16
Daniela Russo, Francesco Merolla, Massimo Mascolo, Gennaro Ilardi, Simona Romano, Silvia Varricchio, Virginia Napolitano, Angela Celetti, Loredana Postiglione, Pier Paolo Di Lorenzo, Luigi Califano, Giovanni Orabona Dell'Aversana, Fabio Astarita, Maria Fiammetta Romano, Stefania Staibano
Up-to-date, several molecular markers of prognosis have been studied in Oral Squamous Cell Carcinoma (OSCC), but none entered in the clinical setting. Therapy of OSCC tumors mainly relies on surgery, radiotherapy and partially on chemotherapy; there is an urgent need for biomarkers able to better stratify OSCC patients' risk to address targeted therapeutic strategies. The role of immune response in the pathogenesis and biological behavior of OSCC has been investigated by several authors, and promising results have been obtained with immune checkpoint inhibitors...
February 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28218669/a-review-of-gaucher-disease-pathophysiology-clinical-presentation-and-treatments
#17
REVIEW
Jérôme Stirnemann, Nadia Belmatoug, Fabrice Camou, Christine Serratrice, Roseline Froissart, Catherine Caillaud, Thierry Levade, Leonardo Astudillo, Jacques Serratrice, Anaïs Brassier, Christian Rose, Thierry Billette de Villemeur, Marc G Berger
Gaucher disease (GD, ORPHA355) is a rare, autosomal recessive genetic disorder. It is caused by a deficiency of the lysosomal enzyme, glucocerebrosidase, which leads to an accumulation of its substrate, glucosylceramide, in macrophages. In the general population, its incidence is approximately 1/40,000 to 1/60,000 births, rising to 1/800 in Ashkenazi Jews. The main cause of the cytopenia, splenomegaly, hepatomegaly, and bone lesions associated with the disease is considered to be the infiltration of the bone marrow, spleen, and liver by Gaucher cells...
February 17, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28217520/elevated-glycated-hemoglobin-predicts-macrosomia-among-asian-indian-pregnant-women-wings-9
#18
Balaji Bhavadharini, Manni Mohanraj Mahalakshmi, Mohan Deepa, Ranjani Harish, Belma Malanda, Arivudainambi Kayal, Anne Belton, Ponnusamy Saravanan, Unnikrishnan Ranjit, Ram Uma, Ranjit Mohan Anjana, Viswanathan Mohan
AIM: The aim of this study was to determine the optimal glycated hemoglobin (HbA1c) cut point for diagnosis of gestational diabetes mellitus (GDM) and to evaluate the usefulness of HbA1c as a prognostic indicator for adverse pregnancy outcomes. METHODS: HbA1c estimations were carried out in 1459 pregnant women attending antenatal care centers in urban and rural Tamil Nadu in South India. An oral glucose tolerance test was carried out using 75 g anhydrous glucose, and GDM was diagnosed using the International Association of the Diabetes and Pregnancy Study Groups criteria...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28217469/clinicopathological-diagnosis-of-orofacial-granulomatosis
#19
Fatma Sule Afsar, Hatice Demirlendi Duran, Gungor Yilmaz, Murat Ermete
Orofacial granulomatosis is a rare chronic inflammatory disorder characterized by persistent or recurrent soft tissue swellings, oral ulceration, and other orofacial features in the absence of an identifiable granulomatous disease. We report a case of a 61-year-old woman with recurrent ulcerations and swellings in her oral mucosa. She was diagnosed as orofacial granulomatosis based upon clinicopathological correlation after exclusion of other granulomatous diseases and showed a favorable response to systemic corticosteroid treatment...
January 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28216129/social-media-use-and-its-association-with-sexual-risk-and-parental-monitoring-among-a-primarily-hispanic-adolescent-population
#20
Dina L Romo, Chelsea Garnett, Alayna P Younger, Melissa S Stockwell, Karen Soren, Marina Catallozzi, Natalie Neu
STUDY OBJECTIVE: This study assesses the association between social media (SM) use with sexual risk, and with parental monitoring among Hispanic adolescents. DESIGN: Self-administered anonymous survey SETTING: Urban primary care clinics PARTICIPANTS: 13-21 year olds primarily Hispanic adolescents MAIN OUTCOME MEASURES: Chi-square and regression analyses controlling for age and gender assessed associations between SM use or sexting and sexual behaviors (kissing, touching genitals, vaginal oral, and anal sex), sexual risk (>4 lifetime partners, >1 recent partner, inconsistent condom use and history of STI diagnosis) and contraceptive use...
February 16, 2017: Journal of Pediatric and Adolescent Gynecology
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