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https://www.readbyqxmd.com/read/29783922/lethal-phlegmonous-colitis
#1
John D Gilbert, Roger W Byard
A 52-year-old man died soon after admission to hospital with a severe metabolic acidosis and likely sepsis. He had a past history of alcohol abuse with withdrawal seizures. An abdominal computed tomography scan showed thickened bowel loops but no obvious ischaemic changes, and a blood culture yielded a pure growth of Escherichia coli. At autopsy, the liver showed well-established micro-nodular cirrhosis with steatosis. The peritoneal cavity contained 200 mL of turbid yellow-brown fluid, and the caecum and ascending colon were unusually thickened...
January 1, 2018: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/29777279/-flap-coverage-using-the-posterior-gluteal-thigh-flap
#2
REVIEW
M K Boyce, T R Mett, R Ipaktchi, P M Vogt
OBJECTIVE: Defect coverage of the sacral, trochanteric or ischial region with durable tissue (gluteal thigh flap). INDICATIONS: Decubital ulcers of the sacral, trochanteric or ischial region after exhaustion of conservative measures. CONTRAINDICATIONS: Moribund or palliative patients who do not benefit from defect coverage and are likely to suffer a life-threatening complication. Noncompliant patients, who cannot follow the postoperative recommendations or protocols in regard to positioning or recurrence prevention...
May 17, 2018: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29769373/the-cortical-damage-early-relapses-and-onset-of-the-progressive-phase-in-multiple-sclerosis
#3
Antonio Scalfari, Chiara Romualdi, Richard S Nicholas, Miriam Mattoscio, Roberta Magliozzi, Aldo Morra, Salvatore Monaco, Paolo A Muraro, Massimiliano Calabrese
OBJECTIVE: To investigate the relationship among cortical radiologic changes, the number of early relapses (ERs), and the long-term course of multiple sclerosis (MS). METHODS: In this cohort study, we assessed the number of cortical lesions (CLs) and white matter (WM) lesions and the cortical thickness (Cth) at clinical onset and after 7.9 mean years among 219 patients with relapsing remitting (RR) MS with 1 (Low-ER), 2 (Mid-ER), and ≥3 (High-ER) ERs during the first 2 years...
May 16, 2018: Neurology
https://www.readbyqxmd.com/read/29753007/evaluating-agreement-histological-features-and-relevance-of-separating-pleomorphic-and-florid-lobular-carcinoma-in-situ-subtypes
#4
Kamaljeet Singh, Cherie Paquette, Elizabeth T Kalife, Yihong Wang, Shamlal Mangray, M Ruhul Quddus Md MPhil, Margaret M Steinhoff
Morphological variants of lobular carcinoma in situ (LCIS) include classical- (CLCIS), pleomorphic- (PLCIS) and florid-type (FLCIS). Treatment guidelines suggest managing PLCIS and FLCIS like ductal carcinoma in situ (DCIS); therefore accurate identification of LCIS subtypes is critical. However significance of separating PLCIS from FLCIS is not clear. Also inter-observer agreement in identifying LCIS subtypes, using contemporary criteria, is not known. We aimed to evaluate inter-observer agreement amongst breast pathologists in diagnosing LCIS subtypes and use the agreement data to justify LCIS classification for management purposes...
May 9, 2018: Human Pathology
https://www.readbyqxmd.com/read/29735503/immunoglobulin-g4-related-disease-of-the-paranasal-sinuses
#5
Anthony Bashyam, Sidhartha Nagala, Fawzia Tahir, Showkat Mirza
Immunoglobulin G4-related disease (IgG4-RD) is becoming increasingly documented. It was first described in relation to autoimmune pancreatitis. Features of the disease include tissue infiltration by IgG4 plasma cells with associated fibrosis and the growth of pseudotumours. A 71-year-old woman presented with increasing right cheek swelling and mild proptosis. Ten years earlier, she had a similar presentation and was diagnosed with an inflammatory pseudotumour. Examination revealed a lesion in the right nasal cavity...
May 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29734943/low-mood-visual-hallucinations-and-falls-heralding-the-onset-of-rapidly-progressive-probable-sporadic-creutzfeldt-jakob-disease-in-a-73-year-old-a-case-report
#6
Daniel Martin Klotz, Rose Sarah Penfold
BACKGROUND: Creutzfeldt-Jakob disease is a rare and rapidly fatal neurodegenerative disease. Since clinicians may see only very few cases during their professional career, it is important to be familiar with the clinical presentation and progression, to perform appropriate investigations, and allow for quick diagnosis. CASE PRESENTATION: A 73-year-old British Caucasian woman presented with acute confusion of 2 weeks' duration on a background of low mood following a recent bereavement...
May 8, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29723687/new-insights-on-diagnostic-reproducibility-of-biphasic-mesotheliomas-a-multi-institutional-evaluation-by-the-international-mesothelioma-panel-from-the-mesopath-reference-center
#7
F Galateau Salle, N Le Stang, A G Nicholson, D Pissaloux, A Churg, S Klebe, V Roggli, H Tazelaar, J M Vignaud, R Attanoos, M B Beasley, H Begueret, F Capron, L Chirieac, M C Copin, S Dacic, C Danel, A Foulet-Roge, A Gibbs, S Giusiano-Courcambeck, K Hiroshima, V Hofman, A Husain, K Kerr, A Marchevsky, K Nabeshima, J M Picquenot, I Rouquette, C Sagan, J Sauter, F Thivolet, W D Travis, M S Tsao, B Weynand, F Damiola, A Scherpereel, J C Pairon, S Lantuejoul, V Rusch, N Girard
BACKGROUND: The 2015 WHO classified malignant mesothelioma into epithelioid [EM], biphasic [BM] and sarcomatoid [SM] for prognostic relevance and treatment decisions. The survival of BM is suspected to correlate with the amount of the sarcomatoid component. The criteria for a sarcomatoid component and the interobserver variability between pathologists for identifying this component are not well described. In ambiguous cases, a "transitional"[TM] subtype has been proposed but was not accepted as a specific subtype in the 2015 WHO...
April 30, 2018: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/29723368/atypical-crusted-scabies-in-a-patient-with-chronic-liver-disease-caused-by-hepatitis-b-and-d-viruses
#8
Mônica Santos, Gustavo Ávila Maquiné, Carolina Talhari, Antonio Pedro Mendes Schettini
Crusted scabies is a less common variant of scabies that is highly contagious, difficult to treat and involves infestation by Sarcoptes scabiei var. hominis. The classical clinical presentation includes crusted, scaly and generally non-pruritic lesions usually located on the head, neck, palmar, plantar and periungual region. It was first described in Norway in 1848 in patients with leprosy who presented with crusted lesions. In this study, we report the case of a patient with crusted scabies with florid clinical manifestations and chronic liver disease due to hepatitis B and delta virus infection...
March 2018: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29721232/management-of-symptomatic-florid-cemento-osseous-dysplasia-literature-review-and-a-case-report
#9
Riccardo Aiuto, Federico Gucciardino, Roberta Rapetti, Sandro Siervo, Andrea-Edoardo Bianch
Introduction: Cemento-osseous dysplasia is a jaw disorder characterized by a reactive process in which normal bone is replaced by connective tissue matrix. There are different Cemento-osseous dysplasia entities. The treatment of these lesions, once diagnosed by radiology, is not required because generally they are asymptomatic. The localization is in the tooth-bearing areas of the jaws and its distribution is symmetric. Case Reports: In this case report, a 57-year-old Caucasian female patient was referred to our attention complaining of painful inflammatory events localized in the right angle of the jaw...
March 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29713422/pulmonary-embolism-from-cement-augmentation-of-the-vertebral-body
#10
REVIEW
Jose Manuel Fernando Ignacio, Katrina Hannah Dizon Ignacio
Pulmonary cement embolism (PCE) can follow cement augmentation procedures for spine fractures due to osteoporosis, traumatic injuries, and painful metastatic lesions. PCE is underreported and it is likely that many cases remain undiagnosed. Risk factors for PCE have been identified, which can help alert clinicians to patients likely to develop the condition, and there are recommended techniques to reduce its incidence. Most patients with PCE are asymptomatic or only develop transient symptoms, although a few may exhibit florid cardiorespiratory manifestations which can ultimately be fatal...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29697424/a-case-of-oral-florid-papillomatosis-verrucous-carcinoma-with-lack-of-evidence-for-human-papillomavirus-involvement
#11
David Dias-Polak, Zipi Kra-Oz, Moran Szwarcwort-Cohen, Aviv Barzilai, Reuven Bergman
No abstract text is available yet for this article.
April 24, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29694947/amyloidoma-of-stomach-a-case-report
#12
Deepika Savant, Michael Adler, Leonard Kahn, Rubina Cocker
OBJECTIVE: Amyloidomas are tumor-like deposits of amyloid. Amyloidoma of the gastrointestinal tract is rare. To the best of our knowledge, this is the first instance of diagnosis of an amyloidoma in the gastrointestinal tract by fine needle aspiration (FNA). STUDY DESIGN: We report a case of a 64-year-old male with a history of ulcerative colitis and primary sclerosing cholangitis who was incidentally found to have a mass in the stomach wall. RESULTS: Initially thought to be gastrointestinal stromal tumor, FNA demonstrated the lesion to be amyloidoma with a prominent giant cell reaction...
April 25, 2018: Acta Cytologica
https://www.readbyqxmd.com/read/29692973/visual-hallucinations-a-novel-complication-after-hemispherectomy
#13
Jonas Vanags, Monisha Sachdev, Gerald Grant, Mohamad A Mikati
Two patients at our center experienced florid visual hallucinations following hemispherectomy. The first patient had drug-resistant left hemispheric focal seizures at 20 months of age from a previous stroke. Following functional hemispherectomy at age 3, he experienced frightening hallucinations 1 month post-operatively lasting 3.5 months. Our second patient underwent subtotal hemispherectomy at age 6 for drug-resistant focal seizures from right hemispheric cortical dysplasia. Eighteen months later he developed scary visual hallucinations during which he would shout and throw things...
2018: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/29690701/-progress-in-the-diagnosis-of-florid-cemento-osseous-dysplasia
#14
P Y Zhang, C Xiao
Florid cemento-osseous dysplasia (FLCOD) is a rare, extensive bone metabolism disorder, which occurs only in the jaw bone. It is usually asymptomatic for a long time and discovered incidentally during a radiological examination. The characteristics of FLCOD in the initial stages are similar to those of periapical granuloma or jaw cyst, which may lead to misdiagnosis. After the lesion is mature, the imaging findings show that radiopaque with a thin radiolucent peripheral halo, which is crucial for the diagnosis of FLCOD, but other jaw lesions have similar imaging findings...
April 9, 2018: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/29680226/a-florid-paranasal-sinus-reaction-from-a-systemic-disease
#15
G Barrett, N Keates, E Kyrodimou, H Wilson
No abstract text is available yet for this article.
April 18, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29662932/combined-extensive-esophageal-squamous-papillomas-and-florid-cardiac-gland-hyperplasia-in-a-patient-with-adenocarcinoma
#16
Takanori Suganuma, Han-Seung Yoon
We report a rare case of extensive esophageal squamous papillomas (ESPs) involving the entire esophagus and florid cardiac gland hyperplasia involving only the lower esophagus in a 39-year-old woman with heartburn and epigastric distress for the past 2 years. Previous esophagogastroduodenoscopy showed multiple ESPs involving the entire esophagus extending 38 cm from the esophageal orifice to the esophagogastric junction (EGJ). Additionally, prominent cardiac gland hyperplasia over the esophageal posterior wall was exhibited extending 12 cm from the mid-esophagus to the EGJ...
March 2018: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/29621551/quantitation-of-hbv-cccdna-in-anti-hbc-positive-liver-donors-by-droplet-digital-pcr-a-new-tool-to-detect-occult-infection
#17
Gian Paolo Caviglia, Maria Lorena Abate, Francesco Tandoi, Alessia Ciancio, Antonio Amoroso, Mauro Salizzoni, Giorgio Maria Saracco, Mario Rizzetto, Renato Romagnoli, Antonina Smedile
BACKGROUND & AIMS: The accurate diagnosis of occult HBV infection (OBI) requires the demonstration of HBV DNA in liver biopsies of HBsAg-negative subjects. However, in clinical practice a latent OBI is deduced by the finding of the antibody to the HB-core antigen (anti-HBc). We investigated the true prevalence of OBI and the molecular features of intrahepatic HBV in anti-HBc-positive subjects. METHODS: The livers of 100 transplant donors (median age 68.2 years; 64 males, 36 females) positive for anti-HBc at standard serologic testing, were examined for total HBV DNA by nested-PCR and for the HBV covalently closed circular DNA (HBV cccDNA) with an in-house droplet digital PCR assay (ddPCR) (Linearity: R2 = 0...
April 2, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29615296/reexamining-post-transplant-lymphoproliferative-disorders-newly-recognized-and-enigmatic-types
#18
REVIEW
Nadine Aguilera, Alejandro A Gru
Post-transplant lymphoproliferative disorders (PTLD) are a known risk for both solid organ transplant and stem cell transplant recipients. Overall transplant recipients have a six fold increase in risk for developing any kind of non-Hodgkin lymphoma and PTLDs occur in up to 10% of SOT recipients. Several new entities have been accepted or renamed in the 2018 update of the WHO classification of tumors of hematopoietic and lymphoid neoplasms, including florid follicular hyperplasia and extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT-lymphoma) (excluding common locations such as stomach and salivary gland)...
March 3, 2018: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/29593914/rituximab-induced-pulmonary-edema-managed-with-extracorporeal-life-support
#19
Jacob R Miller, Warren Isakow, Muhammad F Masood, Patrick Aguilar, Kristen M Sanfilippo, Keki R Balsara, Akinobu Itoh
Though rare, rituximab has been reported to induce severe pulmonary edema. We describe the first report of ECLS utilization for this indication. A 31-year-old female with severe thrombotic thrombocytopenic purpura developed florid pulmonary edema after rituximab infusion. Despite advanced ventilatory settings, she developed severe respiratory acidosis and remained hypoxemic with a significant vasopressor requirement. Since her pulmonary insult was likely transient, ECLS was considered. Due to combined cardiorespiratory failure, she received support with peripheral venoarterial ECLS...
2018: Case Reports in Critical Care
https://www.readbyqxmd.com/read/29552345/cystitis-cystica-and-glandularis-producing-large-bladder-masses-in-a-16-year-old-boy
#20
Christopher Bastianpillai, Ross Warner, Luis Beltran, James Green
The macroscopic appearances of florid cystitis cystica et glandularis can be mistaken for malignancy, and it is therefore important to perform a prompt resection to confirm the histological diagnosis and exclude sinister pathology.
March 2018: JRSM Open
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