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https://www.readbyqxmd.com/read/28550410/different-exogenous-sugars-affect-the-hormone-signal-pathway-and-sugar-metabolism-in-red-globe-vitis-vinifera-l-plantlets-grown-in-vitro-as-shown-by-transcriptomic-analysis
#1
Juan Mao, Wenfang Li, Baoqin Mi, Mohammed Mujitaba Dawuda, Alejandro Calderón-Urrea, Zonghuan Ma, Yongmei Zhang, Baihong Chen
Exogenously applied 2% fructose is the most appropriate carbon source that enhances photosynthesis and growth of grape plantlets compared with the same concentrations of sucrose and glucose. The role of the sugars was regulated by the expression of key candidate genes related to hormones, key metabolic enzymes, and sugar metabolism of grape plantlets ( Vitis vinifera L.) grown in vitro. The addition of sugars including sucrose, glucose, and fructose is known to be very helpful for the development of grape (V...
May 26, 2017: Planta
https://www.readbyqxmd.com/read/28546018/molecular-characterization-and-expression-analysis-of-three-tlr-genes-in-yellow-catfish-pelteobagrus-fulvidraco-responses-to-stimulation-of-aeromonas-hydrophila-and-tlr-ligands
#2
Kai-Lun Wang, Wei Ji, Gui-Rong Zhang, Kai-Jian Wei, Ze-Chao Shi, Xiao-Ting Zhang, Huan Zheng, Qi-Xue Fan
Toll-like receptors (TLRs) are one of the most extensively researched pattern recognition receptors (PRRs) and play an important role in the innate immune system. In this study, partial cDNA sequences of the Pf_TLR18 and Pf_TLR19 genes and complete cDNA sequence of the Pf_TLR21 gene were cloned from yellow catfish (Pelteobagrus fulvidraco). The open reading frames (ORFs) of the Pf_TLR18, Pf_TLR19 and Pf_TLR21 genes were 1956 bp, 2262 bp and 2949 bp in length, encoding 651, 753 and 982 amino acids, respectively...
May 22, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28545961/pecc-correcting-contigs-based-on-paired-end-read-distribution
#3
Min Li, Binbin Wu, Xiaodong Yan, Junwei Luo, Yi Pan, Fang-Xiang Wu, Jianxin Wang
MOTIVATION: Cheap and fast next generation sequencing (NGS) technologies facilitate research of de novo assembly greatly. The reliability of contigs is critical to construct reliable scaffolding. However, contigs generated from most assemblers contain errors because of the limitation of assembly strategy and computation complexity. Among all these errors, the misassembly error is one of the most harmful types. RESULTS: In this paper, we propose a new method named "PECC" to identify and correct misassembly errors in contigs based on the paired-end read distribution...
May 1, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28545740/-factors-associated-with-primary-care-professionals-readiness-to-respond-to-intimate-partner-violence-in-spain
#4
Pilar Murillo, Miguel San Sebastián, Carmen Vives-Cases, Isabel Goicolea
OBJECTIVE: To analyse the Spanish primary care professionals' readiness to respond to intimate partner violence (IPV) in primary care and identify possible determinants that could facilitate a better response. METHOD: A cross-sectional study with a non-probabilistic sampling by convenience was performed among healthcare professionals working in 15 primary care centres in Spain. The Physician Readiness to Manage Intimate Partner Violence Survey (PREMIS), the version validated and translated into Spanish, was the instrument used to collect information about knowledge, opinions and practices regarding intimate partner violence...
May 22, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28545404/gene-dispersion-is-the-key-determinant-of-the-read-count-bias-in-differential-expression-analysis-of-rna-seq-data
#5
Sora Yoon, Dougu Nam
BACKGROUND: In differential expression analysis of RNA-sequencing (RNA-seq) read count data for two sample groups, it is known that highly expressed genes (or longer genes) are more likely to be differentially expressed which is called read count bias (or gene length bias). This bias had great effect on the downstream Gene Ontology over-representation analysis. However, such a bias has not been systematically analyzed for different replicate types of RNA-seq data. RESULTS: We show that the dispersion coefficient of a gene in the negative binomial modeling of read counts is the critical determinant of the read count bias (and gene length bias) by mathematical inference and tests for a number of simulated and real RNA-seq datasets...
May 25, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28545396/transcriptomic-resources-for-the-medicinal-legume-mucuna-pruriens-de-novo-transcriptome-assembly-annotation-identification-and-validation-of-est-ssr-markers
#6
N Sathyanarayana, Ranjith Kumar Pittala, Pankaj Kumar Tripathi, Ratan Chopra, Heikham Russiachand Singh, Vikas Belamkar, Pardeep Kumar Bhardwaj, Jeff J Doyle, Ashley N Egan
BACKGROUND: The medicinal legume Mucuna pruriens (L.) DC. has attracted attention worldwide as a source of the anti-Parkinson's drug L-Dopa. It is also a popular green manure cover crop that offers many agronomic benefits including high protein content, nitrogen fixation and soil nutrients. The plant currently lacks genomic resources and there is limited knowledge on gene expression, metabolic pathways, and genetics of secondary metabolite production. Here, we present transcriptomic resources for M...
May 25, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28545064/transcriptomic-analysis-of-the-response-of-pseudomonas-fluorescens-to-epigallocatechin-gallate-by-rna-seq
#7
Xiaoxiang Liu, Bimiao Shen, Peng Du, Nan Wang, Jiaxue Wang, Jianrong Li, Aihua Sun
Epigallocatechin gallate (EGCG) is a main constituent of green tea polyphenols that are widely used as food preservatives and are considered to be safe for consumption. However, the underlying antimicrobial mechanism of EGCG and the bacterial response to EGCG are not clearly understood. In the present study, a genome-wide transcriptional analysis of a typical spoilage bacterium, Pseudomonas fluorescens that responded to EGCG was performed using RNA-seq technology. A total of 26,365,414 and 23,287,092 clean reads were generated from P...
2017: PloS One
https://www.readbyqxmd.com/read/28544762/the-effect-of-a-tooth-tongue-gel-and-mouthwash-regimen-on-morning-oral-malodour-a-3-week-single-blind-randomized-clinical-trial
#8
E Van der Sluijs, G A Van der Weijden, N L Hennequin-Hoenderdos, D E Slot
AIM: To compare the effects of a regimen consisting of a tooth/tongue gel, tongue cleaner and mouthwash with the effects of using standard fluoride dentifrice on the organoleptic oral malodour score (ORG) and volatile sulphur compounds (VSCs). MATERIALS AND METHODS: A total, 66 non-dental students participated in a 3-week parallel, single-blind, randomized, controlled clinical trial. The test group used a tongue cleaner, a tooth/tongue gel and mouthwash containing amine fluoride/stannous fluoride and zinc lactate as oral malodour counteractive...
May 24, 2017: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/28544418/assessing-knowledge-and-attitudes-about-end-of-life-evaluation-of-three-instruments-designed-for-adults-with-intellectual-disability
#9
R J Stancliffe, M Y Wiese, S Read, G Jeltes, J M Clayton
BACKGROUND: This paper examines the development and psychometric characteristics of three instruments about end of life, designed for use with adults with intellectual disability (ID). Respectively, the instruments assess understanding of the concept of death, end-of-life planning, and fear of death. METHODS: Part 1: instruments were developed or adapted, and pilot tested with 11 adults with ID and 2 disability staff. Part 2: 39 adults with ID and 40 disability staff were assessed on all three instruments...
May 24, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/28544204/receipt-and-use-of-spoken-and-written-over-the-counter-medicine-information-insights-into-australian-and-uk-consumers-experiences
#10
Vivien Tong, David K Raynor, Parisa Aslani
OBJECTIVES: To explore Australian and UK consumers' receipt and use of spoken and written medicine information and examine the role of leaflets for consumers of over-the-counter (OTC) medicines. METHODS: Semistructured interviews were conducted with 37 Australian and 39 UK consumers to explore information received with their most recent OTC medicine purchase, and how information was used at different times post-purchase. Interviews were audio-recorded, transcribed verbatim and thematically analysed...
May 24, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28544077/identification-and-analysis-of-5-enolpyruvylshikimate-3-phosphate-synthase-epsps-gene-from-glyphosate-resistant-ochrobactrum-intermedium-sq20
#11
Sadiqa Firdous, Samina Iqbal, Samina Anwar, Hina Jabeen
BACKGROUND: Glyphosate is a herbicide that acts by inhibition of the enzyme, 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS), entailed in catalysis of an essential step in the biosynthesis of aromatic amino acids. The objective of the current study was to isolate glyphosate resistant bacterial strains and subsequent characterization of the gene(s) encoding glyphosate resistance in these isolates. By enrichment culture technique, a glyphosate resistant bacterium, Ochrobactrum intermedium Sq20 was isolated from glyphosate contaminated indigenous soil and characterized...
May 25, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28542697/incidence-of-atrophic-lesions-in-stargardt-disease-in-the-progression-of-atrophy-secondary-to-stargardt-disease-progstar-study-report-no-5
#12
Rupert W Strauss, Beatriz Muñoz, Alex Ho, Anamika Jha, Michel Michaelides, Saddek Mohand-Said, Artur V Cideciyan, David Birch, Amir H Hariri, Muneeswar G Nittala, SriniVas Sadda, Hendrik P N Scholl
Importance: Outcome measures that are sensitive to disease progression are needed as clinical end points for future treatment trials in Stargardt disease. Objective: To examine the incidence of atrophic lesions of the retinal pigment epithelium in patients with Stargardt disease as determined by fundus autofluorescence imaging. Design, Setting, and Participants: In this retrospective multicenter cohort study, 217 patients 6 years and older at baseline at tertiary referral centers in Europe, the United States, and the United Kingdom who were harboring disease-causing variants in the adenosine triphosphate (ATP)-binding cassette subfamily A member 4 (ABCA4) gene and who met the following criteria were enrolled: (1) at least 1 well-demarcated area of atrophy with a minimum diameter of 300 µm, with the total area of all atrophic lesions being less than or equal to 12 mm2 in at least 1 eye at the most recent visit, and (2) fundus autofluorescence images for at least 2 visits with a minimum of 6 months between at least 2 visits...
May 25, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28542601/the-epidemiology-of-staphylococcus-aureus-carriage-in-patients-attending-inner-city-sexually-transmitted-infections-and-community-clinics-in-calgary-canada
#13
Alejandra Ugarte Torres, Angel Chu, Ron Read, Judy MacDonald, Daniel Gregson, Thomas Louie, Johanna Delongchamp, Linda Ward, Joann McClure, Kunyan Zhang, John Conly
BACKGROUND: Although the nares represent the most common carriage site for traditional hospital-associated strains of Staphylococcus aureus (SA), the predominant site of carriage of SA in the community is less certain. METHODS: We conducted a cross-sectional study in 285 patients attending sexually transmitted diseases and inner-city clinics to evaluate the prevalence, body site colonisation and risk factors associated with carriage of methicillin susceptible SA (MSSA)...
2017: PloS One
https://www.readbyqxmd.com/read/28542006/an-efficient-affordable-optically-stimulated-luminescent-osl-annealer
#14
Sara A Abraham, Samuel J Frank, Kimberlee J Kearfott
Optically stimulated luminescent (OSL) dosimeters are devices used for measuring doses of ionizing radiation. Signal is stored within an OSL material so that when stimulated with light, light of a specific wavelength is emitted in proportion to the integrated ionizing radiation dose. Each interrogation of the material results in the loss of a small fraction of signal, thus allowing multiple interrogations leading to more accurate measurements of dose. In order to reuse a dosimeter, the residual signals from prior doses must be taken into account and subtracted from current readings, adding uncertainty to any future measurements...
July 2017: Health Physics
https://www.readbyqxmd.com/read/28541785/long-term-follow-up-consultation-after-childhood-cancer-in-the-rh%C3%A3-ne-alpes-region-of-france-feedback-from-adult-survivors-and-their-general-practitioners
#15
Claire Berger, Léonie Casagranda, Cécile Faure-Conter, Claire Freycon, Florentina Isfan, Aurélie Robles, Béatrice Trombert-Paviot, Isabelle Guichard, Isabelle Durieu, Pascal Cathebras
PURPOSE: We evaluated the satisfaction of adult survivors of childhood cancers and their general practitioners (GP) after a long-term consultation. METHODS: The first Long-term Follow-up Study in Oncology (SALTO1) is a prospective cohort study of survivors of childhood cancers (except leukemia) diagnosed between 1987 and 1992 in the Rhône-Alpes and Auvergne regions of France. Of the 481 patients eligible for the study, 150 participated in a long-term consultation with a pediatric oncologist and an internist, after which survivors and their GPs received long-term plans and recommendations based on consultation findings...
May 25, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28541229/deeppap-deep-convolutional-networks-for-cervical-cell-classification
#16
Ling Zhang, Le Lu, Isabella Nogues, Ronald Summers, Shaoxiong Liu, Jianhua Yao
Automation-assisted cervical screening via Pap smear or liquid-based cytology (LBC) is a highly effective cell imaging based cancer detection tool, where cells are partitioned into "abnormal" and "normal" categories. However, the success of most traditional classification methods relies on the presence of accurate cell segmentations. Despite sixty years of research in this field, accurate segmentation remains a challenge in the presence of cell clusters and pathologies. Moreover, previous classification methods are only built upon the extraction of hand-crafted features, such as morphology and texture...
May 19, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28541137/clinical-use-of-continuous-glucose-monitoring-in-adults-with-type-2-diabetes
#17
Anders L Carlson, Deborah M Mullen, Richard M Bergenstal
Hemoglobin A1c is an excellent population health measure for the risk of vascular complications in diabetes, while continuous glucose monitoring (CGM) is a tool to help personalize a diabetes treatment plan. The value of CGM in individuals with type 1 diabetes (T1D) has been well demonstrated when compared with utilizing self-monitoring of blood glucose (SMBG) to guide treatment decisions. CGM is a tool for patients and clinicians to visualize the important role that diet, exercise, stress management, and the appropriate selection of diabetes medications can have in managing type 2 diabetes (T2D)...
May 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28541069/reading-between-the-menu-lines-are-restaurants-descriptions-of-healthy-foods-unappealing
#18
Bradley P Turnwald, Dan Jurafsky, Alana Conner, Alia J Crum
OBJECTIVE: As obesity rates continue to climb in America, much of the blame has fallen on the high-calorie meals at popular chain restaurants. Many restaurants have responded by offering "healthy" menu options. Yet menus' descriptions of healthy options may be less attractive than their descriptions of less healthy, standard options. This study examined the hypothesis that the words describing items in healthy menu sections are less appealing than the words describing items in standard menu sections...
May 25, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28540997/a-combination-of-short-and-simple-surfactant-protein-b-and-c-analogues-as-a-new-synthetic-surfactant-in-vitro-and-animal-experiments
#19
Yong Sung Choi, Sung Hoon Chung, Chong Woo Bae
PURPOSE: Pulmonary surfactants for preterm infants contain mostly animal-derived surfactant proteins (SPs), which are essential for lowering surface tension. We prepared artificial pulmonary surfactants using synthetic human SP analogs and performed in vitro and in vivo experiments. MATERIALS AND METHODS: We synthesized peptide analogues that resemble human SP-B (RMLPQLVCRLVLRCSMD) and SP-C (CPVHLKRLLLLLLLLLLLLLLLL). Dipalmitoylphosphatidylcholine (DPPC), phosphatidylglycerol (PG), and palmitic acid (PA) were added and mixed in lyophilized to render powdered surfactant...
July 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28540645/the-effect-of-access-to-information-on-beliefs-surrounding-breast-cancer-in-south-africa
#20
Sarah Rayne, Kathryn Schnippel, Carol Benn, Deirdre Kruger, Kathryne Wright, Cynthia Firnhaber
Breast cancer is the most common cancer affecting women in South Africa. There is little knowledge of beliefs to help identify key areas to improve support and education in this demographically and culturally diverse population. Women with a variety of demographic and socioeconomic characteristics accessing care for breast cancer were asked their agreement to statements of knowledge and beliefs about breast cancer. Of the 259 participants, positive statements of medical cure (87.9%) and family support (90.5%) were most commonly believed...
May 24, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
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