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https://www.readbyqxmd.com/read/27907933/evaluation-of-pregnant-and-postpartum-women-s-knowledge-about-toxoplasmosis-in-rio-grande-rs-brazil
#1
Lis Maurente Lehmann, Paula Costa Santos, Carlos James Scaini
Introduction Toxoplasmosis a parasitic zoonosis of global distribution, responsible for disorders during gestation can cause fetal death or congenital anomalies. Objective To evaluate the knowledge of toxoplasmosis among pregnant and postpartum women treated at the University Hospital of the city of Rio Grande, Rio Grande do Sul, Brazil. Methods This was a cross-sectional study of 100 pregnant and postpartum women at the University Hospital. Participants answered a self-administered questionnaire and gave consent for data relating to serological examinations to be abstracted from their medical records...
December 1, 2016: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/27876900/the-common-zoonotic-protozoal-diseases-causing-abortion
#2
REVIEW
Raafat Mohamed Shaapan
Toxoplasmosis, neosporosis, sarcosporidiosis (sarcocystosis) and trypanosomiasis are the common zoonotic protozoal diseases causing abortion which caused by single-celled protozoan parasites; Toxoplasma gondii, Neospora caninum, Sarcocystis spp and Trypanosoma evansi, respectively. Toxoplasmosis is generally considered the most important disease that causing abortion of both pregnant women and different female animals throughout the world, about third of human being population had antibodies against T. gondii...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27861692/-gestational-and-congenital-toxoplasmosis-a-practical-approach-to-disease-notification
#3
Jaqueline Dario Capobiango, Regina Mitsuka Breganó, Fabiana Maria Ruiz Lopes Mori, Italmar Teodorico Navarro, Josemari Sawczuk de Arruda Campos, Linda Tsuiko Tatakihara, Thalita Bento Talizin, Monica Dos Santos, Tayná Rolim Galvão Pereira, Simone Garani Narciso, Edna Maria Vissoci Reiche
OBJECTIVE: to demonstrate the experience of implanting toxoplasmosis notification during pregnancy and congenital toxoplasmosis in a Sentinel Unit (SU) and describe reported cases. METHODS: this was a descriptive study of the implantation of a notification protocol using a specific notification form for suspected cases of toxoplasmosis in pregnant women and congenital toxoplasmosis in a reference center in Paraná State, Brazil, from August 2013 to August 2014. RESULTS: all 64 suspected cases were notified and case investigation was completed by the SU Epidemiology Sector; 63 received prenatal care and 51 received treatment during pregnancy; 7 of the children being clinically monitored had confirmed diagnosis of congenital toxoplasmosis...
January 2016: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/27794096/high-frequency-detection-of-toxoplasma-gondii-dna-in-human-neonatal-tissue-from-libya
#4
Sameena Z H Haq, Muftah S Abushahama, Omar Gerwash, Jacqueline M Hughes, Elizabeth A Wright, Mohamed S Elmahaishi, Zhao-Rong Lun, Denise Thomasson, Geoff Hide
BACKGROUND: Toxoplasma gondii is a parasite that causes significant disease in humans. Toxoplasmosis is normally asymptomatic, unless associated with congenital transmission, or in immunocompromised people. Congenital transmission generally occurs at low frequencies. In this study, we use PCR to investigate possible congenital transmission of T. gondii during pregnancy in a cohort of mothers from Libya. METHODS: Two hundred and seventy two pregnant women (producing 276 neonates) were recruited to obtain umbilical cord tissue from their neonates at birth; DNA was extracted from that tissue and tested for T...
September 2016: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27788185/congenital-toxoplasmosis-in-chronically-infected-and-subsequently-challenged-ewes
#5
Thaís Rabelo Dos Santos, Gabriela da Silva Magalhães Faria, Bruna Martins Guerreiro, Nathalia Helena Pereira da Silva Dal Pietro, Welber Daniel Zanetti Lopes, Helenara Machado da Silva, João Luis Garcia, Maria Cecília Rui Luvizotto, Katia Denise Saraiva Bresciani, Alvimar José da Costa
This experiment studied congenital transmission in sheep experimentally infected with oocysts of Toxoplasma gondii and reinfected at one of three stages of pregnancy. Twenty ewes were experimentally infected with T. gondii strain ME49 (day 0). After the T. gondii infection became chronic (IFAT≤512), the ewes were allocated with rams for coverage. After the diagnosis of pregnancy, these ewes were allocated into four experimental groups (n = 5): I-reinfected with T. gondii on the 40th day of gestation (DG); II-reinfected on DG 80; III-reinfected on DG 120; and IV-saline solution on DG 120 (not reinfected)...
2016: PloS One
https://www.readbyqxmd.com/read/27766799/seroprevalence-of-toxoplasma-gondii-among-pregnant-women-in-northeast-india
#6
Biswajyoti Borkakoty, Dipankar Biswas, Aniruddha Jakharia, Jagadish Mahanta
OBJECTIVE: Toxoplasma gondii infection is primarily asymptomatic and one third of world's population is estimated to be infected by this protozoan parasite. This study was carried out to determine the seroprevalence of T. gondii infection among pregnant women from north east India, where data on this important parasitic infection is scanty. METHODS: A total of 1141 serum archival samples collected from antenatal clinic attendees in 2007-09, were screened for T. gondii IgG by ELISA and analyzed with their socio demographic information...
October 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27741078/the-utility-of-head-computed-tomography-in-the-evaluation-of-apparent-life-threatening-event
#7
Wayne Stark, Annie Rominger, Fred Warkentine, Kerry Caperell
OBJECTIVE: This study aimed to evaluate the diagnostic utility of empiric head computed tomography (CT) in apparent life threatening event (ALTE). METHODS: This was a retrospective chart review of children younger than 12 months presenting to an urban pediatric hospital and its suburban satellite for an ALTE from October 2009 to December 2012. The ALTE cases were identified as having had a diagnosis of ALTE (International Classification of Diseases, 9th Revision 799...
October 6, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27733631/help-in-the-choice-of-automated-or-semi-automated-immunoassays-for-the-serological-diagnosis-of-toxoplasmosis-evaluation-of-nine-immunoassays-by-the-french-national-reference-center-for-toxoplasmosis
#8
O Villard, B Cimon, C L'Ollivier, H Fricker-Hidalgo, N Godineau, S Houze, L Paris, H Pelloux, I Villena, E Candolfi
Toxoplasmosis, a benign infection, is asymptomatic or pauci-symptomatic in over 80% of cases, excepting immunocompetent patients suffering from ocular toxoplasmosis, as well as immunocompromised patients with opportunistic or congenital toxoplasmosis. Diagnosis is mainly based on serology testing. We thus compared the performance of the nine most commonly-used commercial automated or semi-automated immunoassays for IgG and IgM T. gondii antibody detection: Advia Centaur®, Architect®, AxSYM®, Elecsys®, Enzygnost®, Liaison®, Platelia®, VIDAS®, and VIDIA® assays...
October 12, 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27722099/congenital-toxoplasmosis-clinical-features-outcomes-treatment-and-prevention
#9
Sarman Singh
Toxoplasmosis is caused by a coccidian parasite, Toxoplasma gondii. The parasite is highly prevalent both in humans and in warm-blooded animals. Cat family animals are definitive host, and these animals excrete the infective oocysts in their feces. Humans, though not definitive host, get infection by consuming water or food contaminated with cat feces. Rarely, infection can also take place through transfusing the infected blood, through transplantation of infected organs, or transplacentally from infected mother to fetus...
July 2016: Tropical Parasitology
https://www.readbyqxmd.com/read/27718221/auditory-toxicity-in-late-preterm-and-term-neonates-with-severe-jaundice
#10
Sanjiv B Amin, Satish Saluja, Arvind Saili, Nirupama Laroia, Mark Orlando, Hongyue Wang, Asha Agarwal
AIM: Jaundice may cause auditory toxicity (auditory neuropathy and hearing loss). However, total serum bilirubin (TSB) does not discriminate neonates at risk for auditory toxicity. We compared TSB, bilirubin:albumin molar ratio (BAMR), and unbound bilirubin for their association with auditory toxicity in neonates with severe jaundice (TSB ≥342μmol/L, or that met exchange transfusion). METHOD: Neonates greater or equal to 34 weeks gestational age with severe jaundice during the first 2 postnatal weeks were eligible for prospective cohort study, unless they had craniofacial malformations, chromosomal disorders, toxoplasmosis, other infections, rubella, cytomegalovirus, herpes simplex infections, surgery, or family history of congenital deafness...
October 8, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27707823/toxoplasma-gondii-seroprevalence-in-the-portuguese-population-comparison-of-three-cross-sectional-studies-spanning-three-decades
#11
Maria João Gargaté, Idalina Ferreira, Anabela Vilares, Susana Martins, Carlos Cardoso, Susana Silva, Baltazar Nunes, João Paulo Gomes
BACKGROUND: Toxoplasma gondii is an obligate intracellular protozoan infecting up to one-third of the world's population, constituting a life threat if transmitted from mother to child during pregnancy. In Portugal, there is a lack of knowledge of the current epidemiological situation, as the unique toxoplasmosis National Serological Survey was performed in 1979/1980. METHODS: We studied the seroprevalence trends in the Portuguese general population over the past 3 decades, by assessing chronological spread cross-sectional studies, with special focus on women of childbearing age, by age group, region and gender...
October 5, 2016: BMJ Open
https://www.readbyqxmd.com/read/27644020/progressive-lesions-of-central-nervous-system-in-microcephalic-fetuses-with-suspected-congenital-zika-virus-syndrome
#12
Manoel Sarno, Marcelo Aquino, Kleber Pimentel, Renata Cabral, Gisela Costa, Fernanda Bastos, Carlos Brites
OBJECTIVE: Our aim was to describe the pattern and progression of Central Nervous System (CNS) lesions of microcephalic fetuses with suspected Zika Virus (ZIKV) infection. METHODS: We analyzed fetuses diagnosed with microcephaly after a routine primary care ultrasound scan suspect a fetal microcephaly in Salvador, Brazil, from July/2015 to February/2016 and these pregnancies were followed until delivery. Microcephaly was diagnosed when the head circumference was below two or more standard deviation for gestational age and its relationship with ZIKV infection was defined according to World Health Organization criteria...
September 19, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27605750/sero-epidemiology-and-risk-factors-for-toxoplasma-gondii-among-pregnant-women-in-arab-and-african-countries
#13
Mohamed Alkhatim Alsammani
The epidemiology of toxoplasmosis in pregnancy is a major issue for public health. Primary infection in pregnant women can lead to serious sequelae. This review examined current sero-epidemiology and risks factor data for Toxoplasma gondii in pregnant women in Arab and African countries. A systematic electronic search of published literature was conducted. Data were extracted from relevant studies. Seropositivity is high in both regions. African countries have higher seropositivity than Arab countries due to differences in risk factors...
September 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27562876/prevalence-and-incidence-of-toxoplasmosis-a-retrospective-analysis-of-mother-child-examinations-styria-austria-1995-to-2012
#14
Christian Berghold, Sereina Annik Herzog, Heidelinde Jakse, Andrea Berghold
In Austria, mandatory screening for the prevention of congenital toxoplasmosis stipulates a serological test for antibodies against Toxoplasma gondii as early as possible in pregnancy. In the case of a seronegative result, subsequent tests at intervals of 8 weeks are requested. We analysed serological data from Styria, an Austrian federal state, to determine the seroprevalence and incidence of Toxoplasma infections. The study included 353,599 tests from 103,316 women during 158,571 pregnancies from 1995 to 2012...
August 18, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27528009/seroprevalence-of-toxoplasma-gondii-igg-and-igm-antibodies-and-associated-risk-factors-in-women-of-child-bearing-age-in-njinikom-nw-cameroon
#15
Elvis Chongsi Wam, Leonard Fonkeng Sama, Innocent Mbulli Ali, Walter Akoh Ebile, Lucy Agyingi Aghangu, Christopher Bonglavnyuy Tume
BACKGROUND: Toxoplasmosis is a widely distributed zoonotic disease, caused by the protozoan parasite Toxoplasma gondii. T. Infections can result in stillbirths, abortions or congenital defects during pregnancy, as well as toxoplasmic encephalitis in HIV/AIDS patients. This study aimed to determine the seroprevalence and risk factors for T. gondii infection in women seeking antenatal and medical care in the locality of Njinikom, North West of Cameroon. METHODS: We conducted a cross-sectional study from August to December 2014 consecutively enrolling 178 consenting women aged 15 to 49 years attending antenatal care or medical check-ups at the hospital...
2016: BMC Research Notes
https://www.readbyqxmd.com/read/27504975/evaluation-of-the-western-blotting-method-for-the-diagnosis-of-congenital-toxoplasmosis
#16
Jaqueline Dario Capobiango, Thaís Cabral Monica, Fernanda Pinto Ferreira, Regina Mitsuka-Breganó, Italmar Teodorico Navarro, João Luis Garcia, Edna Maria Vissoci Reiche
OBJECTIVE: To evaluate the Western blotting method for the detection of IgG anti-Toxoplasma gondii (T. gondii) (IgG-WB) in the serum of children with suspected congenital toxoplasmosis. METHODS: We accompanied 47 mothers with acquired toxoplasmosis in pregnancy and their children, between June of 2011 and June of 2014. The IgG-WB was done in house and the test was considered positive if the child had antibodies that recognized at least one band on IgG blots different from the mother's or with greater intensity than the corresponding maternal band, during the first three months of life...
August 6, 2016: Jornal de Pediatria
https://www.readbyqxmd.com/read/27473047/the-impact-of-socioeconomic-factors-on-the-efficiency-of-voluntary-toxoplasmosis-screening-during-pregnancy-a-population-based-study
#17
A E Lange, J R Thyrian, S Wetzka, S Flessa, W Hoffmann, M Zygmunt, C Fusch, H N Lode, M Heckmann
BACKGROUND: Congenital toxoplasmosis is associated with severe complications. German state health insurance covers rubella, but not toxoplasmosis, immunity screening. We analysed the effect of socioeconomic factors on the efficiency of private toxoplasmosis screening during pregnancy. METHODS: Toxoplasmosis and rubella screening data (n = 5402 mothers) were collected within the population-based Survey of Neonates in Pomerania (SNiP). RESULTS: At the first-trimester screening, 34...
2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27455439/incidence-of-symptomatic-congenital-toxoplasmosis-during-10-years-in-a-brazilian-hospital
#18
Adrianne Rahde Bischoff, Luciana Friedrich, Jacobo Melamed Cattan, Flávio Antonio de Freitas Uberti
BACKGROUND: Population seroprevalence and rates of mother-to-child transmission are important in determining the incidence of congenital toxoplasmosis. Mother-to-child transmission depends on the timing of acute maternal infection and treatment during pregnancy. The incidence of congenital toxoplasmosis varies widely across geographic regions, ranging from 1 to 10 cases per 10,000 live births. The incidence of symptomatic disease varies from 0.15 to 0.34 cases per 10,000. METHODS: This is a review of patients treated at a pediatric congenital toxoplasmosis clinic at a university hospital in the south of Brazil, from 2004 to 2014...
July 22, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27445648/multilevel-precision-based-rational-design-of-chemical-inhibitors-targeting-the-hydrophobic-cleft-of-toxoplasma-gondii-apical-membrane-antigen-1-ama1
#19
Umashankar Vetrivel, Shalini Muralikumar, B Mahalakshmi, K Lily Therese, H N Madhavan, Mohamed Alameen, Indhuja Thirumudi
Toxoplasma gondii is an intracellular Apicomplexan parasite and a causative agent of toxoplasmosis in human. It causes encephalitis, uveitis, chorioretinitis, and congenital infection. T. gondii invades the host cell by forming a moving junction (MJ) complex. This complex formation is initiated by intermolecular interactions between the two secretory parasitic proteins-namely, apical membrane antigen 1 (AMA1) and rhoptry neck protein 2 (RON2) and is critically essential for the host invasion process. By this study, we propose two potential leads, NSC95522 and NSC179676 that can efficiently target the AMA1 hydrophobic cleft, which is a hotspot for targeting MJ complex formation...
June 2016: Genomics & Informatics
https://www.readbyqxmd.com/read/27387925/the-burden-of-zoonoses-in-kyrgyzstan-a-systematic-review
#20
Michel J Counotte, Gulnara Minbaeva, Jumagul Usubalieva, Kubanychbek Abdykerimov, Paul R Torgerson
INTRODUCTION: Zoonotic disease (ZD) pose a serious threat to human health in low-income countries. In these countries the human burden of disease is often underestimated due to insufficient monitoring because of insufficient funding. Quantification of the impact of zoonoses helps in prioritizing healthcare needs. Kyrgyzstan is a poor, mountainous country with 48% of the population employed in agriculture and one third of the population living below the poverty line. METHODOLOGY/PRINCIPAL FINDINGS: We have assessed the burden of zoonoses in Kyrgyzstan by conducting a systematic review...
July 2016: PLoS Neglected Tropical Diseases
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