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https://www.readbyqxmd.com/read/28426125/cerclage-use-a-review-of-3-national-guidelines
#1
Jeffrey D Sperling, Joshua D Dahlke, Juan M Gonzalez
Importance: Preterm birth is a major contributor to perinatal morbidity and mortality. The most common intervention performed to improve perinatal outcomes for a woman experiencing cervical dilation in the second trimester without signs or symptoms of preterm labor is the cerclage. Objective: We sought to review and compare available national guidelines on cerclage use. Evidence Acquisition: We performed a descriptive review of 3 national guidelines on cerclage: The American Congress of Obstetricians and Gynecologists Practice Bulletin on "Cerclage for the Management of Cervical Insufficiency," Green-top Guideline from the Royal College of Obstetricians and Gynaecologists entitled "Cervical Cerclage," and the Society of Obstetricians and Gynaecologists of Canada Clinical Practice Bulletin entitled "Cervical Insufficiency and Cervical Cerclage...
April 2017: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/28410856/regional-18f-fluorodeoxyglucose-hypometabolism-is-associated-with-higher-apathy-scores-over-time-in-early-alzheimer-disease
#2
Jennifer R Gatchel, Nancy J Donovan, Joseph J Locascio, J Alex Becker, Dorene M Rentz, Reisa A Sperling, Keith A Johnson, Gad A Marshall
OBJECTIVES: Apathy is among the earliest and most pervasive neuropsychiatric symptoms in prodromal and mild Alzheimer disease (AD) dementia that correlates with functional impairment and disease progression. We investigated the association of apathy with regional 18F-fluorodeoxyglucose (FDG) metabolism in cognitively normal, mild cognitive impairment, and AD dementia subjects from the Alzheimer's Disease Neuroimaging Initiative database. DESIGN: Cross-sectional and longitudinal studies...
January 4, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28391896/lipoprotein-x-disease-in-the-setting-of-severe-cholestatic-hepatobiliary-autoimmune-disease
#3
Robert E Heinl, Heather M Tennant, John C Ricketts, Claire R Rice, Cordelia B Robinson, Pratik B Sandesara, Patrick M Moriarty, Laurence Sperling
Severe cholestatic disease and hyperlipidemia are both commonly encountered by medical professionals. This article reviews the current pathophysiological model of lipoprotein-X syndrome related to 3 cases from 2 academic medical centers in the United States.
January 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28390910/genome-wide-snps-resolve-phylogenetic-relationships-in-the-north-american-spruce-budworm-choristoneura-fumiferana-species-complex
#4
J R Dupuis, B M T Brunet, H M Bird, L M Lumley, G Fagua, B Boyle, R Levesque, M Cusson, J A Powell, F A H Sperling
High throughput sequencing technologies have revolutionized the potential to reconcile incongruence between gene and species trees, and numerous approaches have been developed to take advantage of these advances. Genotyping-by-sequencing is becoming a regular tool for gathering phylogenetic data, yet comprehensive evaluations of phylogenetic methods using these data are sparse. Here we use multiple phylogenetic and population genetic methods for genotyping-by-sequencing data to assess species relationships in a group of forest insect pests, the spruce budworm (Choristoneura fumiferana) species complex...
April 5, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28381517/hippocampal-hypometabolism-in-older-adults-with-memory-complaints-and-increased-amyloid-burden
#5
Patrizia Vannini, Bernard Hanseeuw, Catherine E Munro, Rebecca E Amariglio, Gad A Marshall, Dorene M Rentz, Alvaro Pascual-Leone, Keith A Johnson, Reisa A Sperling
OBJECTIVE: To identify the functional and pathologic correlates underlying subjective memory complaints (SMCs) in cognitively normal older adults. METHODS: Two hundred fifty-one older adults underwent resting-state fluorodeoxyglucose (FDG)-PET and Pittsburg compound B-PET β-amyloid (Aβ) imaging and filled out a questionnaire regarding SMCs. Participants were classified into 2 groups based on their Aβ burden. Age-adjusted voxel-wise correlations were used to examine SMCs, amyloid status (Aβ(+) vs Aβ(-)), and the interaction between SMCs and Aβ status as predictors of metabolism...
April 5, 2017: Neurology
https://www.readbyqxmd.com/read/28377210/similar-patterns-of-neural-activity-predict-memory-function-during-encoding-and-retrieval
#6
James E Kragel, Youssef Ezzyat, Michael R Sperling, Richard Gorniak, Gregory A Worrell, Brent M Berry, Cory Inman, Jui-Jui Lin, Kathryn A Davis, Sandhitsu R Das, Joel M Stein, Barbara C Jobst, Kareem A Zaghloul, Sameer A Sheth, Daniel S Rizzuto, Michael J Kahana
Neural networks that span the medial temporal lobe (MTL), prefrontal cortex, and posterior cortical regions are essential to episodic memory function in humans. Encoding and retrieval are supported by the engagement of both distinct neural pathways across the cortex and common structures within the medial temporal lobes. However, the degree to which memory performance can be determined by neural processing that is common to encoding and retrieval remains to be determined. To identify neural signatures of successful memory function, we administered a delayed free-recall task to 187 neurosurgical patients implanted with subdural or intraparenchymal depth electrodes...
April 1, 2017: NeuroImage
https://www.readbyqxmd.com/read/28376456/strategies-to-prioritize-clinical-options-in-primary-care
#7
EDITORIAL
Patrick J O'Connor, JoAnn M Sperl-Hillen, Karen L Margolis, Thomas E Kottke
No abstract text is available yet for this article.
January 2017: Annals of Family Medicine
https://www.readbyqxmd.com/read/28361219/shoulder-arthroplasty-for-locked-anterior-shoulder-dislocation-a-role-for-the-reversed-design
#8
Joseph M Statz, Bradley S Schoch, Joaquin Sanchez-Sotelo, John W Sperling, Robert H Cofield
INTRODUCTION: Locked anterior shoulder dislocation (LASD) is an uncommon condition associated with bone, articular cartilage, and soft tissue damage. In selected cases, shoulder arthroplasty (SA) may be the best treatment. The purpose of this study was to assess outcomes of SA for LASD. MATERIALS AND METHODS: Between 1976 and 2013, 19 SAs [three hemiarthroplasties (HA), seven total shoulder arthroplasties (TSA), and nine reverse shoulder arthroplasties (RSA), mean age 62 years] were performed for LASD...
March 30, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28359695/use-of-a-shorter-humeral-stem-in-revision-reverse-shoulder-arthroplasty
#9
Eric R Wagner, Joseph M Statz, Matthew T Houdek, Robert H Cofield, Joaquin Sánchez-Sotelo, John W Sperling
BACKGROUND: The purpose of this study was to examine the outcomes of revision reverse arthroplasty using short bone-preserving humeral components in revising a long-stemmed component. METHODS: During a 7-year period, 39 patients who underwent revision reverse shoulder arthroplasty using the long to short humeral component technique were included. The mean age was 72 years. Prior implants used in the primary setting included anatomic (n = 26), hemiarthroplasty (n = 11), and reverse (n = 2)...
March 27, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28345255/lichenoid-folliculitis-a-unifying-concept
#10
Mamina M Turegano, Leonard C Sperling
Skin diseases presenting with keratotic papules, atrophy, cicatricial alopecia, and/or "lichenoid" histopathologic changes have been described under at least 30 names. This family of diseases contains two subgroups, largely based on clinical features: keratosis pilaris atrophicans (KPA; including keratosis pilaris atrophicans faciei/ulerythema ophryogenes, atrophoderma vermiculata , and keratosis follicularis spinulosa decalvans); and the lichen planopilaris (LPP) subgroup (including LPP, frontal fibrosing alopecia, Graham-Little-Piccardi-Lassueur Syndrome, and fibrosing alopecia in a pattern distribution)...
March 26, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28343962/contextually-mediated-spontaneous-retrieval-is-specific-to-the-hippocampus
#11
Nicole M Long, Michael R Sperling, Gregory A Worrell, Kathryn A Davis, Robert E Gross, Bradley C Lega, Barbara C Jobst, Sameer A Sheth, Kareem Zaghloul, Joel M Stein, Michael J Kahana
Although it is now well established that the hippocampus supports memory encoding [1, 2], little is known about hippocampal activity during spontaneous memory retrieval. Recent intracranial electroencephalographic (iEEG) work has shown that hippocampal activity during encoding predicts subsequent temporal organization of memories [3], supporting a role in contextual binding. It is an open question, however, whether the hippocampus similarly supports contextually mediated processes during retrieval. Here, we analyzed iEEG recordings obtained from 215 epilepsy patients as they performed a free recall task...
April 3, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28335018/dissecting-gamma-frequency-activity-during-human-memory-processing
#12
Michal T Kucewicz, Brent M Berry, Vaclav Kremen, Benjamin H Brinkmann, Michael R Sperling, Barbara C Jobst, Robert E Gross, Bradley Lega, Sameer A Sheth, Joel M Stein, Sandthitsu R Das, Richard Gorniak, S Matthew Stead, Daniel S Rizzuto, Michael J Kahana, Gregory A Worrell
Gamma frequency activity (30-150 Hz) is induced in cognitive tasks and is thought to reflect underlying neural processes. Gamma frequency activity can be recorded directly from the human brain using intracranial electrodes implanted in patients undergoing treatment for drug-resistant epilepsy. Previous studies have independently explored narrowband oscillations in the local field potential and broadband power increases. It is not clear, however, which processes contribute to human brain gamma frequency activity, or their dynamics and roles during memory processing...
March 13, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28283594/cued-memory-decline-in-biomarker-defined-preclinical-alzheimer-disease
#13
Kathryn V Papp, Dorene M Rentz, Elizabeth C Mormino, Aaron P Schultz, Rebecca E Amariglio, Yakeel Quiroz, Keith A Johnson, Reisa A Sperling
OBJECTIVE: To determine whether a decline in cued recall is observable in the preclinical stage of Alzheimer disease (AD) in clinically normal older adults with elevated β-amyloid (Aβ) burden on PET imaging. METHODS: Clinically normal older adults underwent baseline neuroimaging (PET to assess Aβ(+/-) status and MRI) and annual neuropsychological testing. Cox proportional hazards models were used to assess the relative risk of cued memory decline (drop of 1, 2, 3, or 4 points on the total score of the Free and Cued Selective Reminding Test) in relation to neuroimaging measures, functional status, age, sex, and education...
April 11, 2017: Neurology
https://www.readbyqxmd.com/read/28276064/instruction-manual-for-the-ilae-2017-operational-classification-of-seizure-types
#14
Robert S Fisher, J Helen Cross, Carol D'Souza, Jacqueline A French, Sheryl R Haut, Norimichi Higurashi, Edouard Hirsch, Floor E Jansen, Lieven Lagae, Solomon L Moshé, Jukka Peltola, Eliane Roulet Perez, Ingrid E Scheffer, Andreas Schulze-Bonhage, Ernest Somerville, Michael Sperling, Elza Márcia Yacubian, Sameer M Zuberi
This companion paper to the introduction of the International League Against Epilepsy (ILAE) 2017 classification of seizure types provides guidance on how to employ the classification. Illustration of the classification is enacted by tables, a glossary of relevant terms, mapping of old to new terms, suggested abbreviations, and examples. Basic and extended versions of the classification are available, depending on the desired degree of detail. Key signs and symptoms of seizures (semiology) are used as a basis for categories of seizures that are focal or generalized from onset or with unknown onset...
April 2017: Epilepsia
https://www.readbyqxmd.com/read/28271960/performance-evaluation-of-a-natural-treatment-system-for-small-communities-composed-of-a-uasb-reactor-maturation-ponds-baffled-and-unbaffled-and-a-granular-rock-filter-in-series
#15
D F C Dias, R G Passos, V A J Rodrigues, M P de Matos, C R S Santos, M von Sperling
Post-treatment of anaerobic reactor effluent with maturation ponds is a good option for small to medium-sized communities in tropical climates. The treatment line investigated, operating in Brazil, with an equivalent capacity to treat domestic sewage from 250 inhabitants, was comprised of a UASB reactor followed by two shallow maturation ponds (unbaffled and baffled) and a granular rock filter (decreasing grain size) in series, requiring an area of only 1.5 m(2).inhabitant(-1). With an overall hydraulic retention time of only 6...
March 8, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28253546/fluorodeoxyglucose-metabolism-associated-with-tau-amyloid-interaction-predicts-memory-decline
#16
Bernard J Hanseeuw, Rebecca A Betensky, Aaron P Schultz, Kathryn V Papp, Elizabeth C Mormino, Jorge Sepulcre, John S Bark, Danielle M Cosio, Molly LaPoint, Jasmeer P Chhatwal, Dorene M Rentz, Reisa A Sperling, Keith A Johnson
OBJECTIVE: The aim of this article was to evaluate in normal older adults and preclinical Alzheimer's disease (AD) the impact of amyloid and regional tauopathy on cerebral glucose metabolism and subsequent memory decline. METHODS: We acquired positron emission tomography using F18 flortaucipir (tau), C11 Pittsburgh compound B (amyloid), and F18 fluorodeoxyglucose in 90 clinically normal elderly of the Harvard Aging Brain Study. RESULTS: Posterior cingulate metabolism decreased when both amyloid and neocortical tau were high and predicted subsequent memory decline in a larger sample of normal elderly...
March 2, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28253478/early-and-late-change-on-the-preclinical-alzheimer-s-cognitive-composite-in-clinically-normal-older-individuals-with-elevated-amyloid-%C3%AE
#17
Elizabeth C Mormino, Kathryn V Papp, Dorene M Rentz, Michael C Donohue, Rebecca Amariglio, Yakeel T Quiroz, Jasmeer Chhatwal, Gad A Marshall, Nancy Donovan, Jonathan Jackson, Jennifer R Gatchel, Bernard J Hanseeuw, Aaron P Schultz, Paul S Aisen, Keith A Johnson, Reisa A Sperling
INTRODUCTION: Sensitive detection of cognitive decline over the course of preclinical Alzheimer's disease is critical as the field moves toward secondary prevention trials. METHODS: We examined amyloid-β (Aβ)-related change in several variations of the preclinical Alzheimer cognitive composite (PACC) and each individual PACC component in clinically normal (CN) older participants in the Harvard Aging Brain Study. We then examined the PACC variations in the Alzheimer's Disease Cooperative Study Prevention Instrument Study as a replication cohort...
February 28, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28243661/reversible-dna-micro-patterning-using-the-fluorous-effect
#18
Gabriella E Flynn, Jamie M Withers, Gerard Macias, Justin R Sperling, Sarah L Henry, Jonathan M Cooper, Glenn A Burley, Alasdair W Clark
We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences.
February 28, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28236572/comparison-of-bacterial-16s-rrna-variable-regions-for-microbiome-surveys-of-ticks
#19
Janet L Sperling, K L Silva-Brandão, M M Brandão, V K Lloyd, S Dang, C S Davis, F A H Sperling, K E Magor
Ticks vector diverse pathogenic bacteria that are important to identify in public health and veterinary contexts. Technological advances in high throughput sequencing have given an unprecedented opportunity to comprehensively characterize bacterial associates of ticks, but recent studies have used different 16S rRNA variable regions and sequence read lengths with little consideration of whether they reveal the same bacterial diversity. We compare the effectiveness of bacterial surveys using three library preparations across nine 16S variable regions and a set of 12 tick specimens (Acari: Ixodidae)...
February 9, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28231417/genetic-and-genomic-evidence-of-niche-partitioning-and-adaptive-radiation-in-mountain-pine-beetle-fungal-symbionts
#20
Dario I Ojeda Alayon, Clement K M Tsui, Nicolas Feau, Arnaud Capron, Braham Dhillon, Yiyuan Zhang, Sepideh Massoumi Alamouti, Celia K Boone, Allan L Carroll, Janice E K Cooke, Amanda D Roe, Felix A H Sperling, Richard C Hamelin
Bark beetles form multipartite symbiotic associations with blue stain fungi (Ophiostomatales, Ascomycota). These fungal symbionts play an important role during the beetle's life cycle by providing nutritional supplementation, overcoming tree defences and modifying host tissues to favour brood development. The maintenance of stable multipartite symbioses with seemingly less competitive symbionts in similar habitats is of fundamental interest to ecology and evolution. We tested the hypothesis that the coexistence of three fungal species associated with the mountain pine beetle is the result of niche partitioning and adaptive radiation using SNP genotyping coupled with genotype-environment association analysis and phenotypic characterization of growth rate under different temperatures...
February 23, 2017: Molecular Ecology
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