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Triple aim goal

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https://www.readbyqxmd.com/read/29679936/controversies-in-monitoring-metastatic-breast-cancer-during-systemic-treatment-results-of-a-gim-gruppo-italiano-mammella-survey
#1
Bonotto Marta, Basile Debora, Gerratana Lorenzo, Pelizzari Giacomo, Bartoletti Michele, Vitale Maria Grazia, Fanotto Valentina, Lisanti Camilla, Mansutti Mauro, Minisini Alessandro Marco, Aprile Giuseppe, De Laurentiis Michele, Montemurro Filippo, Del Mastro Lucia, Puglisi Fabio
BACKGROUND: The optimal strategy for monitoring metastatic breast cancer (M-MBC) is unclear. Nevertheless, M-MBC influences patient's quality of life and it affects the use of resources in terms of both drugs and diagnostic exam prescription. We aim to disclose oncologists' approach on M-MBC, identifying controversial areas. METHODS: An anonymous online survey was conducted among GIM members who, based on their on-field experience, shared their own method for M-MBC planning...
April 18, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29537460/triple-aim-is-triply-tough-can-you-focus-on-three-things-at-once
#2
Katrina E Donahue, Alfred Reid, Elizabeth G Baxley, Charles Carter, Peter J Carek, Mark Robinson, Warren P Newton
BACKGROUND AND OBJECTIVES: The I3 POP Collaborative sought to improve health of patients attending North Carolina, South Carolina, and Virginia primary care teaching practices using the triple aim framework of better quality, appropriate utilization, and enhanced patient experience. We examined change in triple aim measures over 3 years, and identified correlates of improvement. METHODS: Twenty-nine teaching practices representing 23 residency programs participated...
March 2018: Family Medicine
https://www.readbyqxmd.com/read/29529436/sustainability-of-the-use-of-natural-capital-in-a-city-measuring-the-size-and-depth-of-urban-ecological-and-water-footprints
#3
Kai Fang, Qifeng Zhang, Huajun Yu, Yutao Wang, Liang Dong, Lei Shi
The Sustainable Development Goals (SDGs) are limited in their ability to measure progress towards environmental sustainability especially at the city level. The aim of this paper is to provide insights into an integrated assessment of urban sustainability, with emphasis on the significance of the maintenance of natural capital stocks. The use of water and land as critical natural capital in Guiyang, a southeast city in China was investigated by bringing together the ecological footprint (EF), water footprint (WF) and corresponding capacity indicators into an improved three-dimensional (i3D) model...
March 9, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29452560/health-care-efficiencies-consolidation-and-alternative-models-vs-health-care-and-antitrust-regulation-irreconcilable-differences
#4
Michael W King
Despite the U.S. substantially outspending peer high income nations with almost 18% of GDP dedicated to health care, on any number of statistical measurements from life expectancy to birth rates to chronic disease, 1 the U.S. achieves inferior health outcomes. In short, Americans receive a very disappointing return on investment on their health care dollars, causing economic and social strain. 2 Accordingly, the debates rage on: what is the top driver of health care spending? Among the culprits: poor communication and coordination among disparate providers, paperwork required by payors and regulations, well-intentioned physicians overprescribing treatments, drugs and devices, outright fraud and abuse, and medical malpractice litigation...
November 2017: American Journal of Law & Medicine
https://www.readbyqxmd.com/read/29415760/mobile-critical-care-recovery-program-m-ccrp-for-acute-respiratory-failure-survivors-study-protocol-for-a-randomized-controlled-trial
#5
Sikandar Khan, Ashok Biju, Sophia Wang, Sujuan Gao, Omar Irfan, Amanda Harrawood, Stephanie Martinez, Emily Brewer, Anthony Perkins, Frederick W Unverzagt, Sue Lasiter, Ben Zarzaur, Omar Rahman, Malaz Boustani, Babar Khan
BACKGROUND: Patients admitted to intensive care units (ICU) with acute respiratory failure (ARF) face chronic complications that can impede return to normal daily function. A mobile, collaborative critical care model may enhance the recovery of ARF survivors. METHODS: The Mobile Critical Care Recovery Program (m-CCRP) study is a two arm, randomized clinical trial. We will randomize 620 patients admitted to the ICU with acute respiratory failure requiring mechanical ventilation in a 1:1 ratio to one of two arms (310 patients per arm) - m-CCRP intervention versus attention control...
February 7, 2018: Trials
https://www.readbyqxmd.com/read/29382363/identifying-co-endemic-areas-for-major-filarial-infections-in-sub-saharan-africa-seeking-synergies-and-preventing-severe-adverse-events-during-mass-drug-administration-campaigns
#6
Jorge Cano, Maria-Gloria Basáñez, Simon J O'Hanlon, Afework H Tekle, Samuel Wanji, Honorat G Zouré, Maria P Rebollo, Rachel L Pullan
BACKGROUND: Onchocerciasis and lymphatic filariasis (LF) are major filarial infections targeted for elimination in most endemic sub-Saharan Africa (SSA) countries by 2020/2025. The current control strategies are built upon community-directed mass administration of ivermectin (CDTI) for onchocerciasis, and ivermectin plus albendazole for LF, with evidence pointing towards the potential for novel drug regimens. When distributing microfilaricides however, considerable care is needed to minimise the risk of severe adverse events (SAEs) in areas that are co-endemic for onchocerciasis or LF and loiasis...
January 31, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29237903/clinicopathological-features-and-prognostic-evaluation-of-bone-metastasis-in-triple-negative-breast-cancer
#7
Anqi Luo, Fang Wu, Rui Han, Shangke Huang, Yujiao Zhang, Xin Jing, Xinhan Zhao
BACKGROUND: Bone metastases (BMs) are common for breast cancer patients. However, triple-negative breast cancer (TNBC) with BM is relatively rare and few data on it are available. In this study, we aim to investigate the incidence and clinicopathological features and to evaluate the prognosis of TNBC patients with BM. MATERIALS AND METHODS: A total of 616 patients with TNBC (120 out of them had BM) between 2007 and 2011 were involved in the study. Clinicopathological characteristics were statistically analyzed...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29224702/early-intervention-to-restore-function-and-maintain-healthy-trajectory
#8
REVIEW
Juan Jover, Lydia Abasolo
The health of the global population has undergone rapid transformation. Life expectancy and chronic conditions are increasing, and persons aged 65 years or older have become the fastest growing segment of population. The worldwide picture of disease burden is increasingly defined by disability instead of premature mortality. Population growth, ageing and sedentary lifestyles, particularly in developing countries, will result in a crisis for the population health that requires a multi-system response. The growing awareness of the diseases burden increases the need for accurate measurement and assessment of the burden and measurement of the impact of any public health action...
April 2017: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/29035630/a-population-health-measurement-framework-evidence-based-metrics-for-assessing-community-level-population-health-in-the-global-budget-context
#9
Elham Hatef, Elyse C Lasser, Hadi H K Kharrazi, Chad Perman, Russ Montgomery, Jonathan P Weiner
Population health is one of the pillars of the Triple Aim to improve US health care. The authors developed a framework for population health measurement and a proposed set of measures for further exploration to guide the population health efforts in Maryland. The authors searched peer-reviewed, expert-authored literature and current public health measures. Using a semi-structured analysis, a framework was proposed, which consisted of a conceptual model of several domains and identified population health measures addressing them...
October 16, 2017: Population Health Management
https://www.readbyqxmd.com/read/28950862/continental-scale-data-driven-predictive-assessment-of-eliminating-the-vector-borne-disease-lymphatic-filariasis-in-sub-saharan-africa-by-2020
#10
Edwin Michael, Brajendra K Singh, Benjamin K Mayala, Morgan E Smith, Scott Hampton, Jaroslaw Nabrzyski
BACKGROUND: There are growing demands for predicting the prospects of achieving the global elimination of neglected tropical diseases as a result of the institution of large-scale nation-wide intervention programs by the WHO-set target year of 2020. Such predictions will be uncertain due to the impacts that spatial heterogeneity and scaling effects will have on parasite transmission processes, which will introduce significant aggregation errors into any attempt aiming to predict the outcomes of interventions at the broader spatial levels relevant to policy making...
September 27, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28870198/up-modulation-of-plc-%C3%AE-2-reduces-the-number-and-malignancy-of-triple-negative-breast-tumor-cells-with-a-cd133-epcam-phenotype-a-promising-target-for-preventing-progression-of-tnbc
#11
Federica Brugnoli, Silvia Grassilli, Paola Lanuti, Marco Marchisio, Yasamin Al-Qassab, Federica Vezzali, Silvano Capitani, Valeria Bertagnolo
BACKGROUND: The malignant potential of triple negative breast cancer (TNBC) is also dependent on a sub-population of cells with a stem-like phenotype. Among the cancer stem cell markers, CD133 and EpCAM strongly correlate with breast tumor aggressiveness, suggesting that simultaneous targeting of the two surface antigens may be beneficial in treatment of TNBC. Since in TNBC-derived cells we demonstrated that PLC-β2 induces the conversion of CD133(high) to CD133(low) cells, here we explored its possible role in down-modulating the expression of both CD133 and EpCAM and, ultimately, in reducing the number of TNBC cells with a stem-like phenotype...
September 4, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28868934/business-model-framework-applications-in-health-care-a-systematic-review
#12
Jens Jacob Fredriksson, Pamela Mazzocato, Rafiq Muhammed, Carl Savage
It has proven to be a challenge for health care organizations to achieve the Triple Aim. In the business literature, business model frameworks have been used to understand how organizations are aligned to achieve their goals. We conducted a systematic literature review with an explanatory synthesis approach to understand how business model frameworks have been applied in health care. We found a large increase in applications of business model frameworks during the last decade. E-health was the most common context of application...
January 1, 2017: Health Services Management Research
https://www.readbyqxmd.com/read/28661798/getting-the-incentives-right-improving-oral-health-equity-with-universal-school-based-caries-prevention
#13
Richard Niederman, Shulamite S Huang, Anna-Lena Trescher, Stefan Listl
Despite significant financial, training, and program investments, US children's caries experience and inequities continued to increase over the last 20 years. We posit that (1) dental insurance payment systems are not aligned with the current best evidence, exacerbating inequities, and (2) system redesign could meet health care's triple aim and reduce children's caries by 80%. On the basis of 2013 to 2016 Medicaid and private payment rates and the caries prevention literature, we find that effective preventive interventions are either (1) consistently compensated less than ineffective interventions or (2) not compensated at all...
May 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28579478/absolute-venomics-absolute-quantification-of-intact-venom-proteins-through-elemental-mass-spectrometry
#14
Francisco Calderón-Celis, Laura Cid-Barrio, Jorge Ruiz Encinar, Alfredo Sanz-Medel, Juan J Calvete
We report the application of a hybrid element and molecular MS configuration for the parallel absolute quantification of μHPLC-separated intact sulfur-containing venom proteins, via ICP triple quadrupole MS and (32)S/(34)S isotope dilution analysis, and identification by ESI-QToF-MS of the toxins of the medically important African black-necked spitting cobra, Naja nigricollis (Tanzania); New Guinea small-eyed snake, Micropechis ikaheka; and Papuan black snake, Pseudechis papuanus. The main advantage of this approach is that only one generic sulfur-containing standard is required to quantify each and all intact Cys- and/or Met-containing toxins of the venom proteome...
July 5, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28562307/the-eye-of-the-beholder-a-discussion-of-value-and-quality-from-the-perspective-of-families-of-children-and-youth-with-special-health-care-needs
#15
Betsy Anderson, Julie Beckett, Nora Wells, Meg Comeau
There is broad agreement that increasing the cost-effectiveness and quality of health care services, thereby achieving greater value, is imperative given this country's current spiraling costs and poor health outcomes. However, how individuals or stakeholder groups define value may differ significantly. Discussion of value in the context of health care, in particular value-based purchasing and value-based insurance design, must acknowledge that there is no universal consensus definition as to what constitutes value...
May 2017: Pediatrics
https://www.readbyqxmd.com/read/28541262/joint-espghan-naspghan-guidelines-for-the-management-of-helicobacter-pylori-in-children-and-adolescents-update-2016
#16
Nicola L Jones, Sibylle Koletzko, Karen Goodman, Patrick Bontems, Samy Cadranel, Thomas Casswall, Steve Czinn, Benjamin D Gold, Jeannette Guarner, Yoram Elitsur, Matjaž Homan, Nicolas Kalach, Michal Kori, Armando Madrazo, Francis Megraud, Alexandra Papadopoulou, Marion Rowland
BACKGROUND: Because of the changing epidemiology of Helicobacter pylori infection and low efficacy of currently recommended therapies, an update of the European Society for Paediatric Gastroenterology Hepatology and Nutrition/North American Society for Pediatric Gastroenterology, Hepatology and Nutrition recommendations for the diagnosis and management of H pylori infection in children and adolescents is required. METHODS: A systematic review of the literature (time period: 2009-2014) was performed...
June 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28540441/investigating-climate-compatible-development-outcomes-and-their-implications-for-distributive-justice-evidence-from-malawi
#17
Benjamin T Wood, Claire H Quinn, Lindsay C Stringer, Andrew J Dougill
Governments and donors are investing in climate compatible development in order to reduce climate and development vulnerabilities. However, the rate at which climate compatible development is being operationalised has outpaced academic enquiry into the concept. Interventions aiming to achieve climate compatible development "wins" (for development, mitigation, adaptation) can also create negative side-effects. Moreover, benefits and negative side-effects may differ across time and space and have diverse consequences for individuals and groups...
September 2017: Environmental Management
https://www.readbyqxmd.com/read/28499366/the-role-of-brca1-iris-in-the-development-and-progression-of-triple-negative-breast-cancers-in-egypt-possible-link-to-disease-early-lesion
#18
Danielle Bogan, Lucio Meile, Ahmed El Bastawisy, Hend F Yousef, Abdel-Rahman N Zekri, Abeer A Bahnassy, Wael M ElShamy
BACKGROUND: Breast cancer is the most globally diagnosed female cancer, with the triple negative breast cancer (TNBC) being the most aggressive subtype of the disease. In this study we aimed at comparing the effect of BRCA1-IRIS overexpression on the clinico-pathological characteristics in breast cancer patients with TNBC or non-TNBC in the largest comprehensive cancer center in Egypt. METHODS: To reach this goal, we conducted an observational study at the National Cancer Institute (NCI), Cairo University (Cairo, Egypt)...
May 12, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28443805/-a-population-targeted-approach-to-connect-prevention-care-and-welfare-visualising-the-trend
#19
L C Lemmens, H W Drewes, M Lette, C A Baan
OBJECTIVE: To map initiatives in the Netherlands using a population-targeted approach to link prevention, care and welfare. DESIGN: Descriptive investigation, based on conversations and structured interviews. METHOD: We searched for initiatives in which providers in the areas of prevention, care and welfare together with health insurers and/or local authorities attempted to provide the 'triple aim': improving the health of the population and the quality of care, and managing costs...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28420540/what-do-we-mean-when-we-talk-about-the-triple-aim-a-systematic-review-of-evolving-definitions-and-adaptations-of-the-framework-at-the-health-system-level
#20
REVIEW
Gustavo Mery, Shilpi Majumder, Adalsteinn Brown, Mark J Dobrow
Notwithstanding important contributions of the Triple Aim, uncritical enthusiasm regarding the implications of the framework may be leading to inconsistent use, particularly when applied at the health system level, which goes beyond the original positioning of the framework as a strategic organizing principle to guide improvement initiatives at the organizational or local community level. We systematically identified uses of the Triple Aim that extended beyond its original intention to focus on uses at the whole health system level, to assess convergence and divergence with the original definition...
June 2017: Health Policy
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