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https://www.readbyqxmd.com/read/28938744/an-improved-ivm-method-for-cumulus-oocyte-complexes-from-small-follicles-in-polycystic-ovary-syndrome-patients-enhances-oocyte-competence-and-embryo-yield
#1
F Sánchez, F Lolicato, S Romero, M De Vos, H Van Ranst, G Verheyen, E Anckaert, J E J Smitz
STUDY QUESTION: Are meiotic and developmental competence of human oocytes from small (2-8 mm) antral follicles improved by applying an optimized IVM method involving a prematuration step in presence of C-Type Natriuretic Peptide (CNP) followed by a maturation step in presence of FSH and Amphiregulin (AREG)? SUMMARY ANSWER: A strategy involving prematuration culture (PMC) in the presence of CNP followed by IVM using FSH + AREG increases oocyte maturation potential leading to a higher availability of Day 3 embryos and good-quality blastocysts for single embryo transfer...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28938521/beneficial-health-applications-and-medicinal-values-of-pedicularis-plants-a-review
#2
REVIEW
Mohd Iqbal Yatoo, Umesh Dimri, Arumugam Gopalakrishnan, Kumaragurubaran Karthik, Marappan Gopi, Rekha Khandia, Mani Saminathan, Archana Saxena, Mahmoud Alagawany, Mayada Ragab Farag, Ashok Munjal, Kuldeep Dhama
Pedicularis plants (Orobanchaceae), popularly known as lousewort, are found in Asia, Europe, and North America, and have been used in Sowa-Rigpa, the Himalayan art of healing and a traditional system of medicine for treating various ailments in humans. A comprehensive compilation on this valuable medicinal plant is not available, however. The present extensive review provides insight into the salient medicinal properties of Pedicularis plants with respect to various health issues and diseases. Our previous studies on Pedicularis plants from the Changthang region of Ladakh (India) and research advances leading to new developments in this field have prompted this review...
September 18, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28936929/holding-firm-power-push-back-and-opportunities-in-navigating-the-liminal-space-of-critical-qualitative-health-research
#3
Corinne Hart, Jennifer M Poole, Marcia E Facey, Janet A Parsons
Critical qualitative health researchers typically occupy and navigate liminal academic spaces and statuses, with one foot planted in the arts and social sciences and the other in biomedical science. We are at once marginalized and empowered, and this liminality presents both challenges and opportunities. In this article, we draw on our experiences of being (often the lone) critical qualitative health scholars on thesis advisory committees and dissertation examinations, as well as our experiences of publishing and securing funding, to illuminate how power and knowledge relations create conditions that shape the nature of our roles...
October 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28934308/devices-and-tasks-involved-in-the-objective-assessment-of-standing-dynamic-balancing-a-systematic-literature-review
#4
Bálint Petró, Alexandra Papachatzopoulou, Rita M Kiss
BACKGROUND: Static balancing assessment is often complemented with dynamic balancing tasks. Numerous dynamic balancing assessment methods have been developed in recent decades with their corresponding balancing devices and tasks. OBJECTIVE: The aim of this systematic literature review is to identify and categorize existing objective methods of standing dynamic balancing ability assessment with an emphasis on the balancing devices and tasks being used. DATA SOURCES: Three major scientific literature databases (Science Direct, Web of Science, PLoS ONE) and additional sources were used...
2017: PloS One
https://www.readbyqxmd.com/read/28933139/from-art-to-science-the-functional-damage-due-to-thumb-osteoarthritis-finely-described-by-velazquez-300-years-before-its-clinical-description
#5
J H Villafañe, R Cantero-Tellez, S Negrini, P Berjano
Velazquez showed to know the entity of thumb osteoarthritis by finely describing it in one of his paintings. The concepts of anatomical damage, loss of strenght, and functional impairment are transmitted to the observer.
September 21, 2017: Reumatismo
https://www.readbyqxmd.com/read/28929054/prosthetic-rehabilitation-of-a-geriatric-patient-with-squamous-cell-carcinoma-of-the-buccal-mucosa-a-report-of-clinical-challenges
#6
Raghavendra Adaki, Sarvesh Raikar, Kamal Shigli, Sivaranjani Gali
OBJECTIVE: This article aims to highlight the rehabilitation of a geriatric patient with an orofacial cheek defect by an extraoral silicone prosthesis. METHODOLOGY: Structured extra- and intra-oral examination of tissues coupled with a justified choice of impression materials, techniques, and prosthetic rehabilitation with a high-temperature vulcanizing silicone was done. RESULTS: The presence of compressible tissues, static appearance of the prosthesis during patient's facial movements, variability in complexion of the skin around the defect, and manipulating heat-vulcanized silicone were the challenges faced during clinical procedures...
April 2017: International Journal of Pharmaceutical Investigation
https://www.readbyqxmd.com/read/28923034/an-implementation-science-protocol-of-the-women-s-health-coop-in-healthcare-settings-in-cape-town-south-africa-a-stepped-wedge-design
#7
Wendee M Wechsberg, Jacqueline W Ndirangu, Ilene S Speizer, William A Zule, Winnifred Gumula, Courtney Peasant, Felicia A Browne, Laura Dunlap
BACKGROUND: HIV persists as a public health emergency in South Africa, especially among women of childbearing age. In response to the HIV epidemic, the Joint United Nations Programme on HIV/AIDS has put forth the 90-90-90 global goals to achieve an AIDS-free generation by 2020. This goal aspires to have 90% of people living with HIV diagnosed; 90% of those who test positive on sustained antiretroviral therapy (ART); and 90% of those on ART be virally suppressed. Ensuring access to ART is an important first step in reducing HIV incidence, especially among vulnerable populations such as women who use substances and bear the burden of HIV in South Africa...
September 18, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28914147/attitudes-toward-euthanasia-among-turkish-university-students
#8
Gulsen Ulas Karaahmetoglu, Nesibe Sumeyye Kutahyalioglu
This study aims to examine perceptions and attitudes toward euthanasia among university students who are pursuing bachelor's degrees. Although the legalization and application of euthanasia are discussed commonly by health-care professionals and partially by lawyers, the ideas of other segments of society, especially university students, are taken place very rarely. The research was conducted descriptively to determine the ideas of 1,170 students at Kastamonu University from six different departments: arts and sciences, theology, tourism, nursing, school of physical education, and sports with using a questionnaire...
January 1, 2017: Omega
https://www.readbyqxmd.com/read/28904496/serum-amh-level-to-predict-the-hyper-response-in-women-with-pcos-and-non-pcos-undergoing-controlled-ovarian-stimulation-in-art
#9
Radha Vembu, Nellepalli Sanjeeva Reddy
BACKGROUND: It is essential to determine the cut-off value of serum anti-Mullerian hormone (AMH) to predict the hyper response in assisted reproductive technology (ART). There are few studies mentioning the cut-off value for the hyper response in infertile women but not specifically for polycystic ovary syndrome (PCOS) and non-PCOS groups. With this in background, this study was conducted. AIM: To determine the cut-off value of serum AMH to predict the hyper response in women with PCOS and non-PCOS undergoing a controlled ovarian stimulation (COS) in ART...
April 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/28895699/association-between-sleep-related-breathing-disorders-and-academic-performance-among-children-from-concepci%C3%A3-n-chile
#10
Darwin Gatica, Iván Rodríguez-Núñez, Daniel Zenteno, María J Elso, Juan J Montesinos, Carlos Manterola
The objective of this study was to establish an association between academic performance in Math, Language Arts, and Science and the presence of sleep-related breathing disorders (SRBDs) among healthy schoolchildren from the city of Concepción, Chile. Healthy children were defined as those without comorbidities. Outcome measures of interest included the analysis of academic performance in Math, Language Arts, and Science and the presence of SRBD assessed using the Pediatric Sleep Questionnaire. Two-hundred and fifty-six children were included in the study (59...
October 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28895398/nearly-blinking-free-high-purity-single-photon-emission-by-colloidal-inp-znse-quantum-dots
#11
Vigneshwaran Chandrasekaran, Mickaël D Tessier, Dorian Dupont, Pieter Geiregat, Zeger Hens, Edouard Brainis
Colloidal core/shell InP/ZnSe quantum dots (QDs), recently produced using an improved synthesis method, have a great potential in life-science applications as well as in integrated quantum photonics and quantum information processing as single-photon emitters. Single-particle spectroscopy of 10 nm QDs with 3.2 nm cores reveals strong photon antibunching attributed to fast (70 ps) Auger recombination of multiple excitons. The QDs exhibit very good photostability under strong optical excitation. We demonstrate that the antibunching is preserved when the QDs are excited above the saturation intensity of the fundamental-exciton transition...
September 14, 2017: Nano Letters
https://www.readbyqxmd.com/read/28888961/the-seqan-c-template-library-for-efficient-sequence-analysis-a-resource-for-programmers
#12
Knut Reinert, Temesgen Hailemariam Dadi, Marcel Ehrhardt, Hannes Hauswedell, Svenja Mehringer, René Rahn, Jongkyu Kim, Christopher Pockrandt, Jörg Winkler, Enrico Siragusa, Gianvito Urgese, David Weese
BACKGROUND: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome (Venter et al., 2001) would not have been possible without advanced assembly algorithms and the development of practical BWT based read mappers have been instrumental for NGS analysis. However, owing to the high speed of technological progress and the urgent need for bioinformatics tools, there was a widening gap between state-of-the-art algorithmic techniques and the actual algorithmic components of tools that are in widespread use...
September 6, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28883909/computing-platforms-for-big-biological-data-analytics-perspectives-and-challenges
#13
REVIEW
Zekun Yin, Haidong Lan, Guangming Tan, Mian Lu, Athanasios V Vasilakos, Weiguo Liu
The last decade has witnessed an explosion in the amount of available biological sequence data, due to the rapid progress of high-throughput sequencing projects. However, the biological data amount is becoming so great that traditional data analysis platforms and methods can no longer meet the need to rapidly perform data analysis tasks in life sciences. As a result, both biologists and computer scientists are facing the challenge of gaining a profound insight into the deepest biological functions from big biological data...
2017: Computational and Structural Biotechnology Journal
https://www.readbyqxmd.com/read/28879836/care-staff-and-the-creative-arts-exploring-the-context-of-involving-care-personnel-in-arts-interventions
#14
Emma Broome, Tom Dening, Justine Schneider, Dawn Brooker
BACKGROUND: Arts-based interventions play an important role in the care of people with dementia. Yet, creative arts are seldom implemented as a tool to enhance the care and wellbeing of people with dementia. METHODS: We examined the involvement of care staff in creative arts activities in residential care. Aspects of involvement that appear to influence outcomes in people with dementia were identified and analyzed. A broad systematic literature search of MedLine, EMBASE, PsychInfo, CINAHL, ASSIA, SCOPUS, and Web of Science led to the identification of 14 papers...
September 7, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28879788/development-of-an-epitope-based-hiv-1-vaccine-strategy-from-hiv-1-lipopeptide-to-dendritic-based-vaccines
#15
Mathieu Surenaud, Christine Lacabaratz, Gérard Zurawski, Yves Lévy, Jean-Daniel Lelièvre
Development of a safe, effective and globally affordable Human Immunodeficiency Virus strain 1 (HIV-1) vaccine offers the best hope for future control of the HIV-1 pandemic. However, with the exception of the recent RV144 trial, which elicited a modest level of protection against infection, no vaccine candidate has shown efficacy in preventing HIV-1 infection or in controlling virus replication in humans. There is also a great need for a successful immunotherapeutic vaccine since combination antiretroviral therapy (cART) does not eliminate the reservoir of HIV-infected cells...
September 7, 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28879421/the-history-of-rhoton-s-lab
#16
REVIEW
Toshio Matsushima, J Richard Lister, Ken Matsushima, Evandro de Oliveira, Erdener Timurkaynak, David A Peace, Shigeaki Kobayashi
The work performed in Dr. Rhoton's Lab, represented by over 500 publications on microneurosurgical anatomy, greatly contributed to improving the level of neurosurgical treatment throughout the world. The authors reviewed the development and activities of the Lab over 40 years. Dr. Albert L. Rhoton Jr., the founder of, and leader in, this field, displayed great creativity and ingenuity during his life. He devoted himself to perfecting his study methodology, employing high-definition photos and slides to enhance the quality of his published papers...
September 6, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28876552/breast-cancer-and-hiv-a-south-african-perspective-and-a-critical-review-of-the-literature
#17
P Reddy, S Ebrahim, B Singh, S Ramklass, I Buccimazza
BACKGROUND: The diagnosis of breast cancer and concurrent HIV in South Africa is common. The limited current evidence on this subject suggests that the patients thus afflicted appear to be younger, have a more advanced stage of breast cancer, have a higher treatment related complications and poorer outcomes. This paper reviews the literature related to HIV and breast cancer, with a view to improving the standard and quality of care of HIV positive breast cancer patients. METHOD: Pubmed, EBSCOhost, Google scholar and Science Direct electronic databases were searched from 2001 and 2015...
March 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28874638/stigma-and-discrimination-faced-by-hiv-infected-adults-on-antiretroviral-therapy-for-more-than-1-year-in-raichur-taluk-karnataka-india
#18
Shrikanth Muralidharan, Arun Kumar Acharya, Shanthi Margabandu, Shalini Purushotaman, Ranjit Kannan, Sangeeta Mahendrakar, Dinraj Kulkarni
AIM: The aim of this study was to evaluate the stress and discrimination faced by human immunodeficiency virus (HIV)-affected adult patients on antiretroviral therapy (ART) for more than 1 year. MATERIALS AND METHODS: A cross-sectional study was carried out among 170 adults on ART, reporting to the ART center of the District Civil Hospital, for more than 1 year in Raichur Taluk, Karnataka, India. Convenience sampling technique was followed. Descriptive statistics was performed (Chi-square test) using Statistical Package for the Social Sciences version 16...
September 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28872677/immunogenicity-assessment-during-the-development-of-protein-therapeutics
#19
REVIEW
Amy S Rosenberg, Zuben E Sauna
OBJECTIVE: Here we provide a critical review of the state of the art with respect to non-clinical assessments of immunogenicity for therapeutic proteins. KEY FINDINGS: The number of studies on immunogenicity published annually has more than doubled in the last 5 years. The science and technology, which have reached a critical mass, provide multiple of non-clinical approaches (computational, in vitro, ex vivo and animal models) to first predict and then to modify or eliminate T-cell or B-cell epitopes via de-immunization strategies...
September 5, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28869689/cooperative-adsorption-by-porous-frameworks-diffraction-experiment-and-phenomenological-theory
#20
Iurii Dovgaliuk, Farid Nouar, Christian Serre, Yaroslav Filinchuk, Dmitry Chernyshov
Materials science of metal open frameworks is a state-of-the-art field for numerous applications, such as gas storage, sensors and medicine. Two nanoporous frameworks, γ-Mg(BH4)2 and MIL-91(Ti), with different level of structural flexibility were examined with in situ X-ray diffraction guest adsorption-desorption experiments. Both frameworks exhibit a cooperative guest adsorption correlated with a lattice deformation. This cooperativity originates from the long-range interactions between guest molecules mediated by elastic response of the host porous structure...
September 4, 2017: Chemistry: a European Journal
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