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https://www.readbyqxmd.com/read/29346139/blood-biomarkers-for-evaluation-of-perinatal-encephalopathy-state-of-the-art
#1
Ernest M Graham, Allen D Everett, Jean-Christophe Delpech, Frances J Northington
PURPOSE OF REVIEW: The rapid progress in biomarker science is on the threshold of significantly changing clinical care for infants in the neonatal ICU. Infants with neonatal brain injuries will likely be the first group whose management is dramatically altered with point-of-care, rapidly available brain biomarker analysis. Providing an interim update on progress in this area is the purpose of this review. RECENT FINDINGS: Highlighted findings from the past 18 months of publications on biomarkers in neonatal brain injury include; Specific nonbrain markers of cardiac health and global asphyxia continue to provide information on brain injury after hypoxic-ischemic encephalopathy (HIE)...
January 17, 2018: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29346099/cell-membrane-tracking-in-living-brain-tissue-using-differential-interference-contrast-microscopy
#2
John Lee, Ilya Kolb, Craig R Forest, Christopher J Rozell
Differential interference contrast (DIC) microscopy is widely used for observing unstained biological samples that are otherwise optically transparent. Combining this optical technique with machine vision could enable the automation of many life science experiments; however, identifying relevant features under DIC is challenging. In particular, precise tracking of cell boundaries in a thick ( ) slice of tissue has not previously been accomplished. We present a novel deconvolution algorithm that achieves the state-of-the-art performance at identifying and tracking these membrane locations...
April 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29341347/employing-the-arts-for-knowledge-production-and-translation-visualizing-new-possibilities-for-women-speaking-up-about-safety-concerns-in-maternity
#3
Nicola Mackintosh, Jane Sandall, Claire Collison, Wendy Carter, James Harris
OBJECTIVES: This project used animated film to translate research findings into accessible health information aimed at enabling women to speak up and secure professional help for serious safety concerns during pregnancy and after birth. We tested as proof of concept our use of the arts both as product (knowledge production) and process (enabling involvement). BACKGROUND: Emergencies during pregnancy and birth, while unusual, can develop rapidly and unexpectedly, with catastrophic consequences...
January 17, 2018: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29340519/evaluating-the-current-state-of-the-art-of-huntington-disease-research-a-scientometric-analysis
#4
L A Barboza, N C Ghisi
Huntington disease (HD) is an incurable neurodegenerative disorder caused by a dominant mutation on the 4th chromosome. We aim to present a scientometric analysis of the extant scientific undertakings devoted to better understanding HD. Therefore, a quantitative study was performed to examine the current state-of-the-art approaches that foster researchers' understandings of the current knowledge, research trends, and research gaps regarding this disorder. We performed literature searches of articles that were published up to September 2016 in the "ISI Web of Science™" (http://apps...
January 11, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29340440/-administration-practices-myths-and-ideologies
#5
Hugo Spinelli
Administration in the social field is examined based on an analysis of its practices, the rationalist myth and its ideological dimensions. In this way, the article discusses the most frequently utilized concepts (administration, management, gerencia, gestión) and their etymologies; the limitations of teaching administration; the complexity of a practice marked by the dimensions of science, art and the social game; and the ideological question underlying the great thought factory that the general theory of administration has been since the start of the 19th century...
October 2017: Salud Colectiva
https://www.readbyqxmd.com/read/29339474/robust-prediction-of-individual-creative-ability-from-brain-functional-connectivity
#6
Roger E Beaty, Yoed N Kenett, Alexander P Christensen, Monica D Rosenberg, Mathias Benedek, Qunlin Chen, Andreas Fink, Jiang Qiu, Thomas R Kwapil, Michael J Kane, Paul J Silvia
People's ability to think creatively is a primary means of technological and cultural progress, yet the neural architecture of the highly creative brain remains largely undefined. Here, we employed a recently developed method in functional brain imaging analysis-connectome-based predictive modeling-to identify a brain network associated with high-creative ability, using functional magnetic resonance imaging (fMRI) data acquired from 163 participants engaged in a classic divergent thinking task. At the behavioral level, we found a strong correlation between creative thinking ability and self-reported creative behavior and accomplishment in the arts and sciences (r = 0...
January 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29336231/a-new-and-universal-classification-system-of-skin-substitutes-inspired-by-factorial-design
#7
Evan Davison-Kotler, Vaibhav Sharma, Norbert Kang, Elena García-Gareta
The complexity of the dermal layer of skin means that damage to this section can result in permanent impairment of function. Partial or total dermal loss is a feature of deep burns and chronic wounds such as pressure sores or diabetic ulcers. The issues posed by traditional skin grafts have led to substantial research being carried out in the fields of tissue engineering and biomaterials science to develop a vast array of alternative skin substitutes. Given the large number of different materials, manufacturing methods, and techniques for implementation described for artificial skin substitutes, many classification systems have been created to simplify their categorization...
January 16, 2018: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/29333473/charge-migration-and-charge-transfer-in-molecular-systems
#8
REVIEW
Hans Jakob Wörner, Christopher A Arrell, Natalie Banerji, Andrea Cannizzo, Majed Chergui, Akshaya K Das, Peter Hamm, Ursula Keller, Peter M Kraus, Elisa Liberatore, Pablo Lopez-Tarifa, Matteo Lucchini, Markus Meuwly, Chris Milne, Jacques-E Moser, Ursula Rothlisberger, Grigory Smolentsev, Joël Teuscher, Jeroen A van Bokhoven, Oliver Wenger
The transfer of charge at the molecular level plays a fundamental role in many areas of chemistry, physics, biology and materials science. Today, more than 60 years after the seminal work of R. A. Marcus, charge transfer is still a very active field of research. An important recent impetus comes from the ability to resolve ever faster temporal events, down to the attosecond time scale. Such a high temporal resolution now offers the possibility to unravel the most elementary quantum dynamics of both electrons and nuclei that participate in the complex process of charge transfer...
November 2017: Structural Dynamics (Melville, N.Y.)
https://www.readbyqxmd.com/read/29323881/markov-state-models-from-an-art-to-a-science
#9
Brooke E Husic, Vijay S Pande
Markov state models (MSMs) are a powerful framework for analyzing dynamical systems, such as molecular dynamics (MD) simulations, that have gained widespread use over the past several decades. This review offers a complete picture of the MSM field to date, presented for a general audience as a timeline of key developments in the field. We sequentially address early studies that motivated the method, canonical papers that established the use of MSMs for MD analysis, and subsequent advances in software and analysis protocols...
January 11, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29320616/epoxy-nanocomposites-filled-with-carbon-nanoparticles
#10
REVIEW
M Martin-Gallego, V Yuste-Sanchez, R Sanchez-Hidalgo, R Verdejo, M A Lopez-Manchado
Over the past decades, the development of high performance lightweight polymer nanocomposites and, in particular, of epoxy nanocomposites has become one the greatest challenges in material science. The ultimate goal of epoxy nanocomposites is to extrapolate the exceptional intrinsic properties of the nanoparticles to the bulk matrix. However, in spite of the efforts, this objective is still to be attained at commercially attractive scales. Key aspects to achieve this are ultimately the full understanding of network structure, the dispersion degree of the nanoparticles, the interfacial adhesion at the phase boundaries and the control of the localization and orientation of the nanoparticles in the epoxy system...
January 10, 2018: Chemical Record: An Official Publication of the Chemical Society of Japan ... [et Al.]
https://www.readbyqxmd.com/read/29316564/primary-prevention-of-stroke-in-chronic-kidney-disease-patients-a-scientific-update
#11
Stefana Catalina Bilha, Alexandru Burlacu, Dimitrie Siriopol, Luminita Voroneanu, Adrian Covic
BACKGROUND: Although chronic kidney disease (CKD) is an independent risk factor for stroke, official recommendations for the primary prevention of stroke in CKD are generally lacking. SUMMARY: We searched PubMed and ISI Web of Science for randomised controlled trials, observational studies, reviews, meta-analyses and guidelines referring to measures of stroke prevention or to the treatment of stroke-associated risk factors (cardiovascular disease in general and atrial fibrillation (AF), arterial hypertension or carotid artery disease in particular) among the CKD population...
January 9, 2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29315547/introduction-the-transformative-powers-of-aesthetic-experiences-in-psychotherapy
#12
Jesse D Geller
This issue of the Journal of Clinical Psychology: In Session contains seven essays that give expression to three basic convictions. The first is that therapists who are consistently able to help their patients make constructive changes in their lives practice psychotherapy creatively, whether or not they conceive of therapy as an applied science or as an art form. The second is that cultivating an aesthetic perspective on the communicative exchanges that take place in therapy can enhance a therapist's capacity to serve creatively as an agent of change...
January 8, 2018: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29314835/the-state-of-the-art-in-azaborine-chemistry-new-synthetic-methods-and-applications
#13
Zachary X Giustra, Shih-Yuan Liu
Boron-nitrogen heteroarenes hold great promise for practical application in many areas of chemistry. Enduring interest in realizing this potential has in turn driven perennial innovation with respect to these compounds' synthesis. This Perspective discusses in detail the most recent advances in methods pertaining to the preparation of BN-isosteres of benzene, naphthalene, and their derivatives. Additional focus is given to the progress enabled by these syntheses toward functional utility of such BN-heterocycles in biochemistry and pharmacology, materials science, and transition-metal-based catalysis...
January 9, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29313062/art-or-science-an-evidence-based-approach-to-human-facial-beauty-a-quantitative-analysis-towards-an-informed-clinical-aesthetic-practice
#14
REVIEW
Harpal Harrar, Simon Myers, Ali M Ghanem
BACKGROUND: Patients often seek guidance from the aesthetic practitioners regarding treatments to enhance their 'beauty'. Is there a science behind the art of assessment and if so is it measurable? Through the centuries, this question has challenged scholars, artists and surgeons. AIMS AND OBJECTIVES: This study aims to undertake a review of the evidence behind quantitative facial measurements in assessing beauty to help the practitioner in everyday aesthetic practice...
January 8, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29305762/the-dance-of-attention-toward-an-aesthetic-dimension-of-attention-deficit
#15
Kasper Levin
What role does the aesthetics of bodily movement play in the understanding of attention among children diagnosed with attention-deficit/hyperactivity disorder (ADHD)? This article animates a phenomenological approach to attention and embodiment with a special focus on the relation between aesthetic or expressive bodily movement and behavioral awareness in children diagnosed with ADHD. However, beyond this it is argued that the aesthetic aspect of movement calls for an expansion of the phenomenological perspective...
January 5, 2018: Integrative Psychological & Behavioral Science
https://www.readbyqxmd.com/read/29304024/inorganic-membranes-preparation-and-application-for-water-treatment-and-desalination
#16
REVIEW
Ahmad Kayvani Fard, Gordon McKay, Anita Buekenhoudt, Huda Al Sulaiti, Filip Motmans, Marwan Khraisheh, Muataz Atieh
Inorganic membrane science and technology is an attractive field of membrane separation technology, which has been dominated by polymer membranes. Recently, the inorganic membrane has been undergoing rapid development and innovation. Inorganic membranes have the advantage of resisting harsh chemical cleaning, high temperature and wear resistance, high chemical stability, long lifetime, and autoclavable. All of these outstanding properties made inorganic membranes good candidates to be used for water treatment and desalination applications...
January 5, 2018: Materials
https://www.readbyqxmd.com/read/29303129/higher-order-multiple-births-in-nigeria-experiences-challenges-and-neonatal-outcomes-in-a-private-health-facility
#17
B Ezenwa, O Oseni, P Akintan, P Aligwekwe, B Chukwukelu, O Fashola, A Ogunmokun, O Odukoya
OBJECTIVES: The aim of this study is to describe the experience and outcome of higher order multiple (HOM) births in a private tertiary health facility in Nigeria. MATERIALS AND METHODS: This was a retrospective review of records of HOM over 3 years in a private tertiary health facility in Nigeria. Relevant data on HOM births were extracted from both the patients' case notes, admission registers and maternity ward and delivery records of the hospital using a predesigned pro forma...
November 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29303063/coaching-experts-applications-to-surgeons-and-continuing-professional-development
#18
Assad Zahid, Jonathan Hong, Christopher J Young
Surgery is a science and an art, which is mastered through years of training and refined by the accumulation of individual experience and preference. Continuing professional development (CPD) is a concept that emphasizes a self-directed approach to education. Coaching is a process that leads to increased utilization of a person's current skills and resources without counselling or advising. Coaching in surgery could be used to facilitate and optimize feedback and reflection, thus enhancing performance and outcomes through elite performance of an operative procedure...
February 2018: Surgical Innovation
https://www.readbyqxmd.com/read/29303059/association-between-endometriosis-and-preterm-birth-in-women-with-spontaneous-conception-or-using-assisted-reproductive-technology-a-systematic-review-and-meta-analysis-of-cohort-studies
#19
Faustino R Pérez-López, Pablo Villagrasa-Boli, María Muñoz-Olarte, Álex Morera-Grau, Pablo Cruz-Andrés, Adrian V Hernandez
OBJECTIVE: To perform a systematic review and meta-analysis to estimate the effect of endometriosis on preterm birth (PB) risk. METHODS: Searches were conducted in PubMed-MEDLINE, Embase, Scopus, Web of Science, Cochrane Library, Google Scholar, and SciELO for studies published in all languages from inception through April 2017. We included cohort studies evaluating pregnant women with and without endometriosis and conception either by spontaneous conception (SC) or with assisted reproductive technology (ART)...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29299945/a-review-of-plan-library-approaches-in-adaptive-radiotherapy-of-bladder-cancer
#20
Shane D Collins, Michelle M Leech
BACKGROUND: Large variations in the shape and size of the bladder volume are commonly observed in bladder cancer radiotherapy (RT). The clinical target volume (CTV) is therefore frequently inadequately treated and large isotropic margins are inappropriate in terms of dose to organs at risk (OAR); thereby making adaptive radiotherapy (ART) attractive for this tumour site. There are various methods of ART delivery, however, for bladder cancer, plan libraries are frequently used. MATERIAL AND METHODS: A review of published studies on plan libraries for bladder cancer using four databases (Pubmed, Science Direct, Embase and Cochrane Library) was conducted...
January 4, 2018: Acta Oncologica
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