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Andrea Senff-Ribeiro
Proteins from TCTP/HRF family were identified as venom toxins of spiders from different genus. We have found a TCTP toxin in the venom gland of Loxosceles intermedia, a venomous spider very common in South Brazil. TCTP from L. intermedia, named LiTCTP, was cloned, produced in a heterologous prokaryotic system, and the recombinant toxin was biochemically characterized. Our results point that LiTCTP is involved in the inflammatory events of Loxocelism, the clinical signs triggered after Loxosceles sp. bite, which include intense inflammatory reaction at the bite site followed by local necrosis...
2017: Results and Problems in Cell Differentiation
Ma Ascensión Navarro Caballero
Loxocelism is a toxic condition produces by the venom inoculated by the bit of the recluse spider (genus Loxosceles). In can appear in two clinical forms: cutaneous loxocelism and viscerocutaneous Ioxocelim. The species Loxoceles rufescens, found in Spain, is responsible of cases of cutaneous loxocelism. Cutaneous loxocelism starts with an itch, later giving rise to intense pain, and it later takes either a more or less severe necrotic form or an edematous form. The latter, with a better prognosis, is the one we focus on here...
May 2015: Revista de Enfermería
Daniela Regina Buch, Fernanda Nunes Souza, Gabriel Otto Meissner, Adriano Marcelo Morgon, Luiza Helena Gremski, Valéria Pereira Ferrer, Dilza Trevisan-Silva, Fernando Hitomi Matsubara, Mariana Boia-Ferreira, Youssef Bacila Sade, Daniele Chaves-Moreira, Waldemiro Gremski, Silvio Sanches Veiga, Olga Meiri Chaim, Andrea Senff-Ribeiro
Loxosceles spiders are responsible for serious human envenomations worldwide. The collection of symptoms found in victims after accidents is called loxoscelism and is characterized by two clinical conditions: cutaneous loxoscelism and systemic loxocelism. The only specific treatment is serum therapy, in which an antiserum produced with Loxosceles venom is administered to the victims after spider accidents. Our aim was to improve our knowledge, regarding the immunological relationship among toxins from the most epidemiologic important species in Brazil (Loxosceles intermedia, Loxosceles gaucho and Loxosceles laeta)...
December 15, 2015: Toxicon: Official Journal of the International Society on Toxinology
F Farace, M Lissia, A Mele, D R Masia, C Rubino
Bites from Loxosceles spiders can cause few symptoms to gangrenous skin necrosis or even death. To date, the treatment of the violin spider bite is largely unsatisfactory. Although no specific therapy exists, it has been suggested that heparin, steroids, dapsone, experimental antivenin and/or surgical excision may be beneficial. Three rare cases of suspected spider bite and their surgical treatment are reported. On the basis of geographical area, anamnesis and clinical symptoms, we suppose Loxoceles rufescens responsible for these bites...
2006: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
E Calvo Boizas, A Rodríguez Gutiérrez, J C Hernández Criado, I Hernández Vicente, F Gomez Toranzo
Foremost causes of originating shallow painful inflammations on the neck are: boils, carbuncle or infected dermoid cysts and atheroma. When remembering other possible inflammatory sources in this site we cont with insects bites through scarces in our environment. We report one case of spider's bite (Loxoceles rufecens) originating a necrotic neck cellulitis and remind also the several clinical symptoms of arachnid bites scarce in our environment.
2001: Anales Otorrinolaringológicos Ibero-americanos
A W Fenton, P R West, G V Odell, S M Hudiburg, C L Ownby, J N Mills, B T Scroggins, S B Shannon
Citrate has been identified as a major component of honey bee (Apis mellifera) venom by gas liquid chromatography-mass spectrometry. A citrate concentration of 9% was found for dried bee venom by a coupled enzyme assay, aconitase-isocitric dehydrogenase. A liquid honey bee venom would contain 140 mM citrate concentration (if the solids content were 30%). Bee venom phospholipase was inhibited at a 43% level with a citrate concentration of 20 mM and calcium ion at 3 mM with the enzyme assay. Citrate was also found in the venoms of bumble bee, Bombus fervidus, 7%; yellow jacket, Vespula maculifrons, 4%; scorpion, Centruroides sculpturatus, 8%; tarantula, Grammastola cala, 8% and brown recluse spider venom gland extract, Loxoceles reclusa, 1...
June 1995: Toxicon: Official Journal of the International Society on Toxinology
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