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Posterior pharyngitis

Miquel Sureda-Gómez, José M Martín-Durán, Teresa Adell
The βcatenin-dependent Wnt pathway exerts multiple context-dependent roles in embryonic and adult tissues. In planarians, βcatenin-1 is thought to specify posterior identities through the generation of an anteroposterior gradient. However, the existence of such gradient has not been directly demonstrated. Here, we use a specific polyclonal antibody to demonstrate that nuclear βCATENIN-1 exists as an anteroposterior gradient from the pre-pharyngeal region to the tail of the planarian Schmidtea polychroa High levels in the posterior region steadily decrease towards the pre-pharyngeal region but then increase again in the head region...
October 13, 2016: Development
Gamal Abdel-Fattah
OBJECTIVE: Rarely the tonsillar pillars and the soft palate became adherent to the posterior nasopharyngeal wall by strong fibrous tissue due to excessive dissection and cauterization during surgery leading to nasopharyngeal stenosis. Therefore, many treatment modalities are being tried to cure this problem. The aim of this study is to explore our results of modifying the basic technique to accommodate those patients with combined nasopharyngeal stenosis and tonsillar pillars adhesions in one stage...
November 2016: International Journal of Pediatric Otorhinolaryngology
D K Dias, P D Fernando, R D Dissanayake
INTRODUCTION: Oro-facial clefts involving the palate is the commonest structural defect causing velopharyngeal insufficiency (VPI) and poor intelli gibility of speech. Proper repair of the soft palateis a surgical challenge. Posterior-based buccinator myomucosal flap (BMF) is used to lengthen the soft palate of patients who undergo primary palatoplasty at Teaching Hospital, Karapitiya (THK). BMF is a good choice for the repair of medium sized mucosal defects in the oral cavity since it has appropriate thickness, contains mucous membrane with mucous glands and has a rich blood supply...
2016: Ceylon Medical Journal
Sunki Rhee, Masahito Yamamoto, Kei Kitamura, Kasahara Masaaki, Yukio Katori, Gen Murakami, Shin-Ichi Abe
Macrophages play an important role in aging-related muscle atrophy (i.e., sarcopenia). We examined macrophage density in six striated muscles (cricopharyngeus muscle, posterior cricoarytenoideus muscle, genioglossus muscle, masseter muscle, infraspinatus muscle, and external anal sphincter). We examined 14 donated male cadavers and utilized CD68 immunohistochemistry to clarify macrophage density in muscles. The numbers of macrophages per striated muscle fiber in the larynx and pharynx (0.34 and 0.31) were 5-6 times greater than those in the tongue, shoulder, and anus (0...
September 2016: Anatomy & Cell Biology
Jeremy D Meier, Harlan R Muntz
Velopharyngeal dysfunction (VPD) can significantly impair a child's quality of life and may have lasting consequences if inadequately treated. This article reviews the work-up and management options for patients with VPD. An accurate perceptual speech analysis, nasometry, and nasal endoscopy are helpful to appropriately evaluate patients with VPD. Treatment options include nonsurgical management with speech therapy or a speech bulb and surgical approaches including double-opposing Z-plasty, sphincter pharyngoplasty, pharyngeal flap, or posterior wall augmentation...
November 2016: Facial Plastic Surgery Clinics of North America
Shethal Bearelly, Steven W Cheung
Importance: Sensory function in the oral cavity and oropharynx is integral to effective deglutition and speech production. The main hurdle to evaluation of tactile consequences of upper aerodigestive tract diseases and treatments is access to a reliable clinical tool. We propose a rapid and reliable procedure to determine tactile thresholds using buckling monofilaments to advance care. Objective: To develop novel sensory testing monofilaments and map tactile thresholds of oral cavity and oropharyngeal structures...
September 29, 2016: JAMA Otolaryngology—Head & Neck Surgery
Yoshihiro Takasugi, Koichi Futagawa, Tatsuo Konishi, Daisuke Morimoto, Takahiko Okuda
PURPOSE: Most reported cases of nasopharyngeal laceration following impingement during nasotracheal intubation involved tube insertion via the right nostril. We postulated that recesses on the posterior wall of the nasopharynx might be associated with tube impingement. Using multiplanar imaging and clinical statistics, we evaluated whether anatomical variations in the recesses are related to successful intubation via the right nostril. METHODS: Using multiplanar computed tomography (CT) images of 97 patients, we investigated the locations of recesses relative to the mid-sagittal plane, nasal floor plane and posterior end of the nasal septum, and their shapes...
September 27, 2016: Journal of Anesthesia
Michaela Czerneková, K Ingemar Jönsson, Lukasz Chajec, Sebastian Student, Izabela Poprawa
Tun formation is an essential morphological adaptation for entering the anhydrobiotic state in tardigrades, but its internal structure has rarely been investigated. We present the structure and ultrastructure of organs and cells in desiccated Richtersius coronifer by transmission and scanning electron microscopy, confocal microscopy, and histochemical methods. A 3D reconstruction of the body organization of the tun stage is also presented. The tun formation during anhydrobiosis of tardigrades is a process of anterior-posterior body contraction, which relocates some organs such as the pharyngeal bulb...
September 27, 2016: Protoplasma
N Makaram, R Gohil, Q Gardiner, J Manickavasagam
We report an unusual case of nasopharyngeal carcinoma (NPC), presenting initially as a retropharyngeal collection. We discuss the investigation, diagnosis and management of NPC and furthermore review the literature of NPC, emphasising the varied presentation. A 44-year-old Caucasian male ex-smoker presented with a 10-day history of a painless left-sided neck lump; progressive dysphagia and unintentional weight loss. Examination demonstrated a large left posterior pharyngeal swelling with soft palatal effacement, confirmed on nasoendoscopy...
2016: BMJ Case Reports
K Sudhakar, Y K Areti, L N Kurnutala, G Jibara, S M Lashley, S B Nanduri, P S Chami, M T Kakoory, C A Maynard
Objective: To evaluate the clinical features of angio-oedema (AE) and their correlation with fibre-optic nasolaryngoscopy (FNL) findings. Methods: The charts of adult AE patients for 225 episodes who were admitted as in-patients from January 2002 through December 2012 were reviewed. Results: Of the 51 episodes (22.6%) with laryngeal swelling, 16 had exclusively laryngeal swelling; without oropharyngeal swelling. Swelling of the laryngeal structures on FNL was not significantly associated with a suspected aetiology or history of AE or allergies...
March 9, 2016: West Indian Medical Journal
S Onodera, J Furuya, H Yamamoto, Y Tamada, H Kondo
Wearing dentures and dysphagia are common in older individuals; however, it is still unknown how dentures affect oral and pharyngeal swallowing. The purpose of this study was to reveal the effects of wearing and removing dentures on oropharyngeal movements during pharyngeal swallowing in the feeding sequence of solid food. Participants were 25 edentulous volunteers (nine men, 16 women; mean age 76·2 years) who wore complete dentures. The test food was minced agar jelly containing barium sulphate. Subjects were instructed to feed and swallow the test food with or without dentures during observation using videofluorography...
November 2016: Journal of Oral Rehabilitation
Troy Camarata, Aleksandr Vasilyev, Michael Hadjiargyrou
Mustn1 is a small nuclear protein that is involved in the development and regeneration of the musculoskeletal system. Previous work established a role for Mustn1 in myogenic and chondrogenic differentiation. In addition, recent evidence suggests a potential role for Mustn1 in cilia function in zebrafish. A detailed study of Mustn1 expression has yet to be conducted in zebrafish. As such, we report herein the cloning of the zebrafish Mustn1 orthologs, mustn1a and mustn1b, and their expression during zebrafish embryonic and larval development...
November 15, 2016: Gene
Marta Figueiredo, Joana Clara Silva, Ana Sofia Santos, Vitor Proa, Isabel Alcobia, Rita Zilhão, António Cidadão, Hélia Neves
The avian thymus and parathyroids (T/PT) common primordium derives from the endoderm of the third and fourth pharyngeal pouches (3/4PP). The molecular mechanisms that govern T/PT development are not fully understood. Here we study the effects of Notch and Hedgehog (Hh) signalling modulation during common primordium development using in vitro, in vivo and in ovo approaches. The impairment of Notch activity reduced Foxn1/thymus-fated and Gcm2/Pth/parathyroid-fated domains in the 3/4PP and further compromised the development of the parathyroid glands...
October 15, 2016: Developmental Biology
Jong-Chi Oh
Tongue-hold swallow (THS) is a therapeutic maneuver used to increase the posterior pharyngeal wall motion during swallowing. This maneuver has also been reported to result in increased activation of the suprahyoid muscles. The hypothesis of this study was that the degree of suprahyoid muscle activation would depend on the tongue protrusion-length. The aim of this study was to investigate the activation levels of the suprahyoid muscles by surface electromyography (sEMG) while performing the THS maneuver at three tongue-protrusion lengths...
2016: SpringerPlus
Ehsan Eslami, Eliot S Katz, Mariam Baghdady, Kenneth Abramovitch, Mohamed I Masoud
OBJECTIVE: To systematically review the literature correlating upper airway parameters between lateral cephalograms (LC) and cone-beam computed tomography (CBCT) or computed tomography (CT) scans to determine the utility of using LC to predict three-dimensional airway parameters. MATERIALS AND METHODS: Both electronic and manual searches of the included studies were performed by two reviewers, and the quality of the studies that met selection criteria were assessed...
July 27, 2016: Angle Orthodontist
Ai Kawamoto-Hirano, Yohei Honkura, Masahito Yamamoto, Shin-Ichi Abe, Gen Murakami, Yukio Katori
Although the pharyngeal wall is well known to have high elasticity, the distribution of submucosal elastic fibers has not been described. Observations of histological sections of the mid and lower pharyngeal walls from 15 elderly donated cadavers were made. We found two distinct submucosal tissue layers with a high content of elastic fibers (tentatively termed the "submucosal elastic laminae"). The inferolateral elastic lamina was restricted to the level from the upper part of the arytenoid to the lower end of the inferior cornu of the thyroid cartilage...
October 2016: Dysphagia
Stian Wærsted, Thomas Dethloff
This case report describes an aberrant course of the internal carotid artery (ICA) in a patient presenting with symptoms of globus sensation, mild chronic cough and occasional aspiration. Clinically, a pulsating oro-hypopharyngeal tumour could only be visualized by fiberlaryngoscopy. A CT-scan showed a tortuous ICA protruding into the lateral and posterior pharyngeal wall. This condition may need treatment in itself, and it can lead to co-morbidity and serious surgical complications in undiagnosed patients...
July 11, 2016: Ugeskrift for Laeger
Şenol Çomoğlu, Ece Çomoğlu, Necati Enver, Eren Yılmaz, Mehmet Çelik, Beldan Polat, Murat Ulusan, İsmet Aslan, Kemal Değer
OBJECTIVES: This study aims to evaluate the effect of paratracheal lymph node (PTLN) metastasis on survival in patients with advanced laryngeal and hypopharyngeal cancer. PATIENTS AND METHODS: Medical records of advanced laryngeal and hypopharyngeal cancers who underwent surgery between May 1995 and June 2008 were assessed and 78 of the patients (63 males, 15 females; mean age 55±11.3 years; range 25 to 76 years) who has PTLN metastasis were included in this study...
July 2016: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
Daniel Leduc
New deep-sea nematodes of the family Microlaimidae are described from the Southwest Pacific Ocean and Ross Sea. Microlaimus korari n. sp. is characterised by annulated cuticle with longitudinal bars, round amphideal aperture slightly smaller than the cryptospiral amphideal fovea, spacious and heavily cuticularised buccal cavity with large dorsal tooth and right subventral tooth situated anteriorly relative to left subventral tooth, slender spicules 4.4 cloacal body diameters long, and gubernaculum 1.2 cloacal body diameters long with laterally curved distal end and swollen proximal end...
2016: Zootaxa
Benze Shi, Kuidong Xu
Four new species of Epacanthion are described from intertidal sandy sediments in the Nanji Islands National Marine Natural Reserve from the East China Sea. Males of all four new species have short spicules (< 2 anal body diameter) and a characteristic cervical circle of distinctly short and densely arranged setae at the pharyngeal region: Epacanthion hirsutum sp. nov. with a cervical circle of a single row of setae posterior to the nerve ring; E. longicaudatum sp. nov. with a cervical circle of 16 bundles each composed of six setae in two longitudinal rows posterior to the nerve ring; E...
2016: Zootaxa
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