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https://www.readbyqxmd.com/read/28548050/reversible-crystalline-amorphous-phase-transformation-in-si-nanosheets-with-lithi-delithiation
#1
Jeong Min Park, Jae-Hyun Cho, Jung Hoon Ha, Hae-Sik Kim, Sung-Wook Kim, Jaejun Lee, Kyung Yoon Chung, Byung-Won Cho, Heon-Jin Choi
Silicon (Si) has a large theoretical capacity of 4200 mAhg(-1) and has great potential as a high-performance anode material for Li ion batteries (LIBs). Meanwhile, nanostructures can exploit the potential of Si and, accordingly, many zero-dimensional (0D) and one-dimensional (1D) Si nanostructures have been studied. Herein, we report on two-dimensional (2D) Si nanostructures, Si nanosheets (SiNSs), as anodes for LIBs. These 2D Si nanostructures, with a thickness as low 5 nm and widths of several micrometers, show reversible crystalline-amorphous phase transformations with the lithi-/delithiation by the dimensionality of morphology and large surface area...
May 26, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28547764/visibility-of-focal-liver-lesions-comparison-between-kupffer-phase-of-ceus-with-sonazoid-and-hepatobiliary-phase-of-gadoxetic-acid-enhanced-mri
#2
Woo Young Yang, Hee Sun Park, Young Jun Kim, Mi Hye Yu, Sung Il Jung, Hae Jeong Jeon
BACKGROUND: To investigate the agreement between Kupffer phase of Sonazoid contrast-enhanced sonography (CEUS) and hepatobiliary phase of gadoxetic acid-enhanced MRI in the evaluation of focal liver lesions (FLLs). METHODS: One hundred fifty-four FLLs in 154 patients who underwent both Sonazoid CEUS and gadoxetic acid-enhanced liver MRI were included in this retrospective study. FLL visibility on the Kupffer-phase images was graded as one (invisible or isoenhancing), two (vaguely visible or vaguely hypoenhancing), or three (clearly visible or clearly hypoenhancing), and that on the hepatobiliary-phase images of MRI was graded as one (invisible or hyper/isointense), two (vaguely visible or weakly hypointense), or three (clearly visible or strongly hypointense)...
May 26, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28546366/characteristics-and-clinical-outcomes-of-end-stage-renal-disease-patients-on-peritoneal-dialysis-for-over-15-years-a-single-center-experience
#3
Youn Kyung Kee, Jung Tak Park, Chang-Yun Yoon, Hyoungnae Kim, Seohyun Park, Hae Ryong Yun, Su-Young Jung, Jong Hyun Jhee, Hyung Jung Oh, Seung Hyeok Han, Tae-Hyun Yoo, Shin-Wook Kang
♦Background: Maintaining peritoneal dialysis (PD) for a long time is problematic owing to a number of factors. This study aimed to clarify the characteristics and examine the clinical outcomes of patients who received PD as a long-term dialysis modality. ♦ Methods: All end-stage renal disease (ESRD) patients who initiated PD at Yonsei University Health System between 1987 and 2000 were screened. Patients who maintained PD for over 15 years were classified as the long-term PD group and those who were treated with PD for less than 5 years were included in the short-term PD group...
May 25, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28545035/novel-ppar%C3%AE-agonist-mhy553-alleviates-hepatic-steatosis-by-increasing-fatty-acid-oxidation-and-decreasing-inflammation-during-aging
#4
Seong Min Kim, Bonggi Lee, Hye Jin An, Dae Hyun Kim, Kyung Chul Park, Sang-Gyun Noh, Ki Wung Chung, Eun Kyeong Lee, Kyung Mok Kim, Do Hyun Kim, Su Jeong Kim, Pusoon Chun, Ho Jeong Lee, Hyung Ryong Moon, Hae Young Chung
Hepatic steatosis is frequently observed in obese and aged individuals. Because hepatic steatosis is closely associated with metabolic syndromes, including insulin resistance, dyslipidemia, and inflammation, numerous efforts have been made to develop compounds that ameliorate it. Here, a novel peroxisome proliferator-activated receptor (PPAR) α agonist, 4-(benzo[d]thiazol-2-yl)benzene-1,3-diol (MHY553) was developed, and investigated its beneficial effects on hepatic steatosis using young and old Sprague-Dawley rats and HepG2 cells...
May 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28541004/the-effect-of-peripheral-crf-peptide-and-water-avoidance-stress-on-colonic-and-gastric-transit-in-guinea-pigs
#5
Zahid Hussain, Hae Won Kim, Cheal Wung Huh, Young Ju Lee, Hyojin Park
Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are common gastrointestinal (GI) diseases; however, there is frequent overlap between FD and IBS patients. Emerging evidence links the activation of corticotropin releasing factor (CRF) receptors with stress-related alterations of gastric and colonic motor function. Therefore, we investigated the effect of peripheral CRF peptide and water avoidance stress (WAS) on upper and lower GI transit in guinea pigs. Dosages 1, 3, and 10 μg/kg of CRF were injected intraperitoneally (IP) in fasted guinea pigs 30 minutes prior to the intragastric administration of charcoal mix to measure upper GI transit...
July 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28540759/baseline-bcr-abl1-transcript-type-of-e13a2-and-large-spleen-size-are-predictors-of-poor-long-term-outcomes-in-chronic-phase-chronic-myeloid-leukemia-patients-who-failed-to-achieve-an-early-molecular-response-after-3-months-of-imatinib-therapy
#6
Sung-Eun Lee, Soo-Young Choi, Soo-Hyun Kim, Hye-Young Song, Hae-Lyun Yoo, Mi-Young Lee, Hee-Jeong Hwang, Ki-Hoon Kang, Kyung-Mi Kee, Eun-Jung Jang, Dong-Wook Kim
We conducted this study to identify the factors for predicting poor outcomes in chronic myeloid leukemia patients who failed to achieve a 3-month early molecular response (EMR). Of the 413 newly diagnosed, chronic phase, chronic myeloid leukemia patients receiving imatinib (IM), 120 (29.1%) failed to achieve a 3-month EMR. With a median follow-up of 67.0 months, 39 patients continued IM treatment with at least complete cytogenetic response (CCyR), and 81 patients permanently discontinued IM treatment. The cumulative incidence rates of CCyR and major molecular response (MMR) by 3 years were 90...
May 25, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28540153/depression-among-middle-aged-persons
#7
EDITORIAL
Hae-Wol Cho, Chaeshin Chu
No abstract text is available yet for this article.
April 2017: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/28539943/the-hierarchical-implications-of-internet-gaming-disorder-criteria-which-indicate-more-severe-pathology
#8
Seung-Yup Lee, Hae Kook Lee, Hyunsuk Jeong, Hyeon Woo Yim, Soo-Young Bhang, Sun-Jin Jo, Kyung-Young Baek, Eunjin Kim, Min Seob Kim, Jung-Seok Choi, Yong-Sil Kweon
OBJECTIVE: To explore the structure of Internet gaming disorder (IGD) criteria and their distribution according to the different severity level of IGD. The associations of psychiatric comorbidities to each IGD symptom and to the IGD severity were also investigated. METHODS: Consecutively recruited 330 Korean middle school students underwent face-to-face diagnostic interviews to assess their gaming problems by clinicians. The psychiatric comorbidities were also evaluated with a semi-structured instrument...
May 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28539710/anti-inflammatory-effects-of-kotmin13-a-mixed-herbal-medicine-in-lps-stimulated-raw-264-7-cells-and-mouse-edema-models
#9
Eujin Lee, Sun-Gun Kim, Na-Young Park, Hyo-Hyun Park, Kyu-Tae Jeong, Jongkeun Choi, In-Hae Lee, Hwadong Lee, Eunkyung Lee
BACKGROUND: A Korean herbal medicine, KOTMIN13, composed of Inula japonica Thunberg, Trichosanthes kirilowii Maximowicz var. japonica kitamura, Peucedanum praeruptorum Dunn, and Allium macrostemon Bge, has been used for anti-allergic and anti-asthmatic treatment in oriental clinics, but its activity has not been investigated. MATERIALS AND METHODS: To evaluate the anti-inflammatory activity of KOTMIN13 for in vitro study, LPS-stimulated RAW 264.7 cells were used to induce the production and expression of inflammatory mediators and its mechanisms...
April 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28539609/manipulation-of-rat-movement-via-nigrostriatal-stimulation-controlled-by-human-visually-evoked-potentials
#10
Bonkon Koo, Chin Su Koh, Hae-Yong Park, Hwan-Gon Lee, Jin Woo Chang, Seungjin Choi, Hyung-Cheul Shin
Here, we report that the development of a brain-to-brain interface (BBI) system that enables a human user to manipulate rat movement without any previous training. In our model, the remotely-guided rats (known as ratbots) successfully navigated a T-maze via contralateral turning behaviour induced by electrical stimulation of the nigrostriatal (NS) pathway by a brain- computer interface (BCI) based on the human controller's steady-state visually evoked potentials (SSVEPs). The system allowed human participants to manipulate rat movement with an average success rate of 82...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28539594/toward-a-nearly-defect-free-coating-via-high-energy-plasma-sparks
#11
Mosab Kaseem, Hae Woong Yang, Young Gun Ko
A nearly defect-free metal-oxide-based coating structure was made on Al-Mg-Si alloy by plasma electrolytic oxidation at high current density accompanying high-energy plasma sparks. The present coatings were performed at two different current densities of 50 and 125 mA/cm(2) in the alkaline-phosphate-based electrolytes with different concentrations of sodium hexafluoroaluminate (Na3AlF6). The addition of (Na3AlF6) to the electrolyte used in this study would result in a decrease in the size of the micropore, and a reasonably defect-free coating structure was achieved in the sample treated at high current density of 125 mA/cm(2)...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28539161/single-cell-rna-seq-unveils-tumor-microenvironment
#12
Hae-Ock Lee, Woong-Yang Park
Single cell transcriptome analysis became an essential tool to define cell types or sub-populations within a heterogeneous bulk population. Tumor-associated microenvironment is a complex ecosystem with numerous cell types, supporting the tumor growth, angiogenesis, immune evasion, and metastasis. With the success of checkpoint inhibitors targeting the immune cell compartment, tumor microenvironment is an emerging anti-cancer target and its understanding becomes an imminent issue in the cancer biology.
May 25, 2017: BMB Reports
https://www.readbyqxmd.com/read/28539036/a-case-of-tuberculous-peritonitis-presenting-as-small-bowel-obstruction
#13
Hae Koo Kim, Sung Eun Kim, Moo In Park, Seun Ja Park, Won Moon, Jae Hyun Kim, Kyoungwon Jung, Yong Jin Nam
The peritoneum is one of the common extrapulmonary sites of tuberculosis infection. Patients with underlying end-stage renal or liver disease are frequently complicated by tuberculous peritonitis; however, the diagnosis of the tuberculous peritonitis is difficult due to its insidious nature, well as its variability in presentation and limitation of available diagnostic tests. Once diagnosed, the preferred treatment is usually antituberculous therapy in uncomplicated cases. However, surgical treatment may also be required for complicated cases, such as small bowel obstruction or perforation...
May 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28538146/ligand-mediated-folding-of-the-ompa-periplasmic-domain-from-acinetobacter-baumannii
#14
Ameeq Ul Mushtaq, Jeong Soon Park, Sung-Hun Bae, Hye-Yeon Kim, Kwon Joo Yeo, Eunha Hwang, Ki Yong Lee, Jun-Goo Jee, Hae-Kap Cheong, Young Ho Jeon
The periplasmic domain of OmpA from Acinetobacter baumannii (AbOmpA-PD) binds to diaminopimelate and anchors the outer membrane to the peptidoglycan layer in the cell wall. Although the crystal structure of AbOmpA-PD with its ligands has been reported, the mechanism of ligand-mediated folding of AbOmpA remains elusive. Here, we report that in vitro refolded apo-AbOmpA-PD in the absence of ligand exists as a mixture of two partially folded forms in solution: mostly unfolded (apo-state I) and hololike (apo-state II) states...
May 23, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28537889/immune-signature-of-metastatic-breast-cancer-identifying-predictive-markers-of-immunotherapy-response
#15
Ji-Yeon Kim, Eunjin Lee, Kyunghee Park, Woong-Yang Park, Hae Hyun Jung, Jin Seok Ahn, Young-Hyuck Im, Yeon Hee Park
In breast cancer (BC), up to 10-20% patients were known to have clinical benefit with immune checkpoint inhibitors, and biomarkers are needed for optimal use of this multi-potential therapeutic strategy. Accordingly, we conducted an experiment to identify expression of genes associated with immune checkpoints that represent potential targets of cancer immunotherapy. We performed whole-transcriptome sequencing and whole-exome sequencing using 37 refractory BC specimens. In the immune pathway gene set expression analysis, we found that HER2 expression and previous taxane treatment were positively correlated with high expression of immune gene set expression (p = 0...
May 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28537057/physician-directed-diabetes-education-without-a-medication-change-and-associated-patient-outcomes
#16
Hun Sung Kim, Hyunah Kim, Hae Kyung Yang, Eun Young Lee, Yoo Jin Jeong, Tong Min Kim, So Jung Yang, Seo Yeon Baik, Seung Hwan Lee, Jae Hyoung Cho, In Young Choi, Hyeon Woo Yim, Bong Yun Cha
BACKGROUND: When patients with diabetes mellitus (DM) are first referred to a hospital from primary health care clinics, physicians have to decide whether to administer an oral hypoglycemic agent (OHA) immediately or postpone a medication change in favor of diabetes education regarding diet or exercise. The aim of this study was to determine the effect of diabetes education alone (without alterations in diabetes medication) on blood glucose levels. METHODS: The study was conducted between January 2009 and December 2013 and included patients with DM...
May 12, 2017: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/28536928/reduction-malarplasty-that-uses-malar-setback-without-resection-of-malar-body-strip
#17
Hae-Won Yang, Jin-Joo Hong, Youn-Taek Koo
BACKGROUND: Various surgical methods have been developed and used to reduce prominent malar bones. The most common reduction malarplasty methods are resection of the bone strip of the malar bone with L-osteotomy or I-osteotomy, followed by setback and fixation. However, these methods could be associated with complications due to the bone strip resection. The present article introduces an effective and safe method that reduces the zygoma without resection of a malar bone strip. METHODS: Through preauricular and intraoral incisions, we performed the current L-osteotomy without resection of the malar bone strip using a reciprocating saw...
May 23, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28535954/sol-gel-derived-bioactive-glass-nanoparticle-incorporated-glass-ionomer-cement-with-or-without-chitosan-for-enhanced-mechanical-and-biomineralization-properties
#18
Dong-Ae Kim, Jung-Hwan Lee, Soo-Kyung Jun, Hae-Won Kim, Mohamed Eltohamy, Hae-Hyoung Lee
OBJECTIVE: This study investigated the mechanical and in vitro biological properties (in immortalized human dental pulp stem cells (ihDPSCs)) of bioactive glass nanoparticle (BGN)-incorporated glass ionomer cement (GIC) with or without chitosan as a binder. METHODS: After the BGNs were synthesized and characterized, three experimental GICs and a control (conventional GIC) that differed in the additive incorporated into a commercial GIC liquid (Hy-bond, Shofu, Japan) were produced: BG5 (5wt% of BGNs), CL0...
May 20, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28535549/epidural-dexamethasone-influences-postoperative-analgesia-after-major-abdominal-surgery
#19
Jeong-Min Hong, Kyung-Hoon Kim, Hyeon Jeong Lee, Jae-Young Kwon, Hae-Kyu Kim, Hyae-Jin Kim, Ah-Reum Cho, Wang-Seok Do, Hyo Sung Kim
BACKGROUND: Epidurally administered dexamethasone might reduce postoperative pain. However, the effect of epidural administration of dexamethasone on postoperative epidural analgesia in major abdominal surgery has been doubtful. OBJECTIVES: To investigate the effects and optimal dose of epidural dexamethasone on pain after major abdominal surgery. STUDY DESIGN: A prospective randomized, double-blind study. SETTING: University hospital...
May 2017: Pain Physician
https://www.readbyqxmd.com/read/28534342/the-effect-of-preoperative-occlusion-therapy-on-long-term-outcome-after-surgery-for-early-onset-exotropia
#20
Kwang Hoon Shin, Iris Naheah Kim, Hae Jung Paik
PURPOSE: To investigate the effect of preoperative part-time occlusion therapy on long-term surgical success in early-onset exotropia. METHODS: The medical records of patients who underwent surgery for exotropia with onset before the first year of age and who were followed for ≥3 years were reviewed. Patients were divided into two groups according to the degree of compliance with part-time occlusion therapy: the good compliance group (>50% adherence rate) and the poor compliance group (≤50% adherence rate)...
May 11, 2017: Korean Journal of Ophthalmology: KJO
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