keyword
MENU ▼
Read by QxMD icon Read
search

Elderly + generation

keyword
https://www.readbyqxmd.com/read/28526493/improving-comfort-around-dying-in-elderly-people-a-cluster-randomised-controlled-trial
#1
Kim Beernaert, Tinne Smets, Joachim Cohen, Rebecca Verhofstede, Massimo Costantini, Kim Eecloo, Nele Van Den Noortgate, Luc Deliens
BACKGROUND: Over 50% of elderly people die in acute hospital settings, where the quality of end-of-life care is often suboptimum. We aimed to assess the effectiveness of the Care Programme for the Last Days of Life (CAREFuL) at improving comfort and quality of care in the dying phase in elderly people. METHODS: We did a cluster randomised controlled trial in acute geriatric wards in ten hospitals in Flemish Region, Belgium, between Oct 1, 2012, and March 31, 2015...
May 16, 2017: Lancet
https://www.readbyqxmd.com/read/28515634/difference-in-quality-of-life-and-associated-factors-among-the-elderly-in-rural-vietnam
#2
REVIEW
T Van Nguyen, H Van Nguyen, T Duc Nguyen, T Van Nguyen, T The Nguyen
BACKGROUND: In Vietnam today, many generations remain living together in a family. With escalating urbanization and population aging, mental health disorders and the quality of life (QoL) among the elderly are gradually presenting themselves as of great concern. The objective of this study was to examine gender differences in QoL and some associated factors among the elderly in rural Vietnam using the QoL scale of WHO (WHOQOL-BREF). METHODS: A cross-sectional study using quantitative methods...
March 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/28509786/igg4-related-disease-of-the-biliary-tract-and-pancreas-clinical-and-experimental-advances
#3
Lowiek M Hubers, Ulrich Beuers
PURPOSE OF REVIEW: IgG4-related disease (IgG4-RD) is an immune-mediated disease of unknown cause. It predominantly affects the biliary tract [IgG4-associated cholangitis (IAC)] and pancreas [autoimmune pancreatitis (AIP)] of mostly elderly men. Accurate diagnostic tests are lacking. Patients benefit from predniso(lo)ne treatment. However, disease relapse is often seen. This review will address pathophysiological aspects and advances in diagnostic and therapeutic strategies. RECENT FINDINGS: The role of IgG1 and IgG4 in the pathophysiology of IgG4-RD was studied in mice which showed more intense organ damage of pancreas and salivary glands when IgG1 rather than IgG4 of patients with IgG4-RD was injected...
May 13, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28505974/state-of-play-in-alzheimer-s-disease-genetics
#4
Jin-Bao Zhu, Chen-Chen Tan, Lan Tan, Jin-Tai Yu
Alzheimer's disease (AD), the main form of dementia in the elderly, is the most common progressive neurodegenerative disease characterized by rapidly progressive cognitive dysfunction and behavior impairment. AD exhibits a considerable heritability and great advances have been made in approaches to searching the genetic etiology of AD. In AD genetic studies, methods have developed from classic linkage-based and candidate-gene-based association studies to genome-wide association studies (GWAS) and next generation sequencing...
May 11, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28503138/enhanced-feedback-related-negativity-in-alzheimer-s-disease
#5
Eri Nitta, Keiichi Onoda, Fuminori Ishitobi, Ryota Okazaki, Seiji Mishima, Atsushi Nagai, Shuhei Yamaguchi
Alzheimer's disease (AD), the most common cause of dementia in the elderly, results in the impairment of executive function, including that of performance monitoring. Feedback-related negativity (FRN) is an electrophysiological measure reflecting the activity of this monitoring system via feedback signals, and is generated from the anterior cingulate cortex. However, there have been no reports on FRN in AD. Based on prior aging studies, we hypothesized that FRN would decrease in AD patients. To assess this, FRN was measured in healthy individuals and those with AD during a simple gambling task involving positive and negative feedback stimuli...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28500981/some-consequences-of-normal-aging-for-generating-conceptual-explanations-a-case-study-of-vitalist-biology
#6
Nathan Tardiff, Igor Bascandziev, Kaitlin Sandor, Susan Carey, Deborah Zaitchik
Accumulating evidence suggests that not only diseases of old age, but also normal aging, affect elderly adults' ability to draw on the framework theories that structure our abstract causal-explanatory knowledge, knowledge that we use to make sense of the world. One such framework theory, the cross-culturally universal vitalist biology, gives meaning to the abstract concepts life and death. Previous work shows that many elderly adults are animists, claiming that active, moving entities such as the sun and the wind are alive (Zaitchik & Solomon, 2008)...
June 2017: Cognitive Psychology
https://www.readbyqxmd.com/read/28497484/cd44-variant-isoform-9-emerges-in-response-to-injury-and-contributes-to-the-regeneration-of-the-gastric-epithelium
#7
Nina Bertaux-Skeirik, Mark Wunderlich, Emma Teal, Jayati Chakrabarti, Jacek Biesiada, Maxime Mahe, Nambirajan Sundaram, Joel Gabre, Jennifer Hawkins, Jian Gao, Amy C Engevik, Li Yang, Jiang Wang, James R Goldenring, Joseph E Qualls, Mario Medvedovic, Michael A Helmrath, Tayyab Diwan, James C Mulloy, Yana Zavros
Cluster-of-differentiation gene 44, in particular CD44 variant isoform 9 (CD44v9), emerges during regeneration of the gastric epithelium in response to injury. In particular, CD44v9 is expressed within Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) glands during gastric repair, but the function is unknown. Here we tested the hypothesis that age dependent expression of CD44v9 marks a regenerative cell lineage responsive to infiltrating macrophages during regeneration of the gastric epithelium. Acetic acid injury was induced in CD44-deficient (CD44KO) and C57BL/6 (BL6) mice...
May 12, 2017: Journal of Pathology
https://www.readbyqxmd.com/read/28496937/amiodarone-induced-third-degree-atrioventricular-block-and-extreme-qt-prolongation-generating-torsade-des-pointes-in-paroxysmal-atrial-fibrillation
#8
Orlando Robert Sequeira, Nelson Javier Aquino, Nancy Beatriz Gómez, Laura Beatriz García, Cristina Cáceres, Oscar A Lovera, Osmar Antonio Centurión
Amiodarone is still the most potent antiarrhythmic drug in the prevention of life threatening ventricular arrhythmias and demonstrates a very low incidence of torsade de pointes. An unusual case of an 81-year-old woman who developed serious abnormalities of the conduction system of the heart and torsade des pointes during intravenous infusion of amiodarone for the treatment of paroxysmal atrial fibrillation is described. To the best of our knowledge, this is the first case showing an association of intravenous amiodarone-induced third degree atrioventricular block and extreme QT interval prolongation generating torsade des pointes in a patient with paroxysmal atrial fibrillation who required an implantable cardioverter-defibrillator...
October 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/28484488/progress-in-eeg-based-brain-robot-interaction-systems
#9
REVIEW
Xiaoqian Mao, Mengfan Li, Wei Li, Linwei Niu, Bin Xian, Ming Zeng, Genshe Chen
The most popular noninvasive Brain Robot Interaction (BRI) technology uses the electroencephalogram- (EEG-) based Brain Computer Interface (BCI), to serve as an additional communication channel, for robot control via brainwaves. This technology is promising for elderly or disabled patient assistance with daily life. The key issue of a BRI system is to identify human mental activities, by decoding brainwaves, acquired with an EEG device. Compared with other BCI applications, such as word speller, the development of these applications may be more challenging since control of robot systems via brainwaves must consider surrounding environment feedback in real-time, robot mechanical kinematics, and dynamics, as well as robot control architecture and behavior...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/28479556/wearable-and-mobile-technology-for-safe-and-active-living
#10
Mette Røhne, Elin Sundby Boysen, Dag Ausen
The study explores how mobile safety alarms can be utilized for ambient assisted living (AAL), and provides elderly safety, autonomy, independence and mobility. The aim is to generate knowledge on usage, usability and technical requirements to harvest the potential benefits of using wearable and mobile technologies in care for safe and active living. The study is based on real life pilots in three Norwegian municipalities with 71 users, their caregivers and relatives. Pilot users wore the mobile safety alarm while performing their daily activities - indoor and outdoor...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28476526/restrictive-transfusion-in-radical-cystectomy-is-safe
#11
Sumeet Syan-Bhanvadia, Siri Drangsholt, Swar Shah, Jie Cai, Gus Miranda, Hooman Djaladat, Siamak Daneshmand
INTRODUCTION AND OBJECTIVE: Perioperative blood transfusion (PBT) is commonplace in radical cystectomy (RC) and has been linked to poorer oncologic outcomes. Limiting PBT in this largely elderly and comorbid population has not been studied. Herein, we first investigate the safety of a restrictive transfusion protocol (RTP) in patients undergoing RC for urothelial carcinoma and then compare oncologic outcomes between patients who did and did not receive PBT. METHODS: Outcomes for 173 consecutive patients meeting inclusion criteria undergoing RC for urothelial carcinoma from April 2010 to June 2014 by a single surgeon employing RTP were analyzed from an institutional review board-approved, prospectively collected database...
May 2, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28472530/investigation-of-the-benefits-of-early-malnutrition-screening-with-telehealth-follow-up-in-elderly-acute-medical-admissions
#12
Yogesh Sharma, Campbell Thompson, Billingsley Kaambwa, Rashmi Shahi, Paul Hakendorf, Michelle Miller
Background.: The benefit of providing early nutrition intervention and its continuation post-discharge in older hospitalized patients is unclear. This study examined efficacy of such an intervention in older patients discharged from acute care. Methods.: In this randomized controlled trial, 148 malnourished patients were randomized to receive either a nutrition intervention for three months or usual care. Intervention included an individualized nutrition care plan plus monthly post-discharge telehealth follow-up whereas control patients received intervention only upon referral by their treating clinicians...
May 4, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28470430/is-mortality-due-to-primary-malignant-brain-and-other-central-nervous-system-tumors-decreasing
#13
Haley Gittleman, Courtney Kromer, Quinn T Ostrom, Rachel Blanda, Jeffrey Russell, Carol Kruchko, Jill S Barnholtz-Sloan
Primary malignant brain and other central nervous system tumors (BT) are a rare cancer that causes morbidity and mortality disproportionate to their incidence. This study presents the most up-to-date mortality data for malignant BT in the United States (US) by histology groupings, age, race, and sex. Mortality rates for malignant BT were generated using the Center for Disease Control's National Vital Statistics Systems (NVSS, ~100% of US) data from 1975 to 2012. Histology-specific incidence-based mortality rates were calculated using the National Cancer Institute's Surveillance, Epidemiology, and End-Results 9 (SEER9, ~9...
May 3, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28469622/the-involvement-of-nitric-oxide-in-integration-of-plant-physiological-and-ultrastructural-adjustments-in-response-to-arsenic
#14
Fernanda S Farnese, Juraci A Oliveira, Elder A S Paiva, Paulo E Menezes-Silva, Adinan A da Silva, Fernanda V Campos, Cléberson Ribeiro
High arsenic (As) concentrations are toxic to all the living organisms and the cellular response to this metalloid requires the involvement of cell signaling agents, such as nitric oxide (NO). The As toxicity and NO signaling were analyzed in Pistia stratiotes leaves. Plants were exposed to four treatments, for 24 h: control; SNP [sodium nitroprusside (NO donor); 0.1 mg L(-1)]; As (1.5 mg L(-1)) and As + SNP (1.5 and 0.1 mg L(-1), respectively). The absorption of As increased the concentration of reactive oxygen species and triggered changes in the primary metabolism of the plants...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28466669/measurement-of-confidence-the-development-and-psychometric-evaluation-of-a-stroke-specific-measure-of-confidence
#15
Jane C Horne, Nadina B Lincoln, Pip A Logan
OBJECTIVE: To design, develop and psychometrically evaluate a stroke-specific measure of confidence, the Confidence after Stroke Measure (CaSM). DESIGN: Cross-sectional. SETTING: Adults in the community. PARTICIPANTS: Stroke survivors and healthy elderly participants. METHODS: Questionnaire items were generated based on the literature and qualitative interviews and piloted with expert groups to establish face validity...
April 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28462215/condylar-constrained-system-in-primary-total-knee-replacement-our-experience-and-literature-review
#16
Luigi Sabatini, Salvatore Risitano, Lorenzo Rissolio, Andrea Bonani, Francesco Atzori, Alessandro Massè
BACKGROUND: Constrained condylar knee (CCK) prosthesis are common used for revision surgery but can also help surgeons to improve implant stability in primary knee arthroplasty, in fact in severe knee arthrosis with serious deformity associated with a significant instability a more constrained articulation is required. With introduction of second generation of semi-constrained prosthesis, rate of complication is real decreased and a good survival rate and functional score results is showed...
March 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28461251/mitophagy-and-age-related-pathologies-development-of-new-therapeutics-by-targeting-mitochondrial-turnover
#17
REVIEW
Konstantinos Palikaras, Ioanna Daskalaki, Maria Markaki, Nektarios Tavernarakis
Mitochondria are highly dynamic and semi-autonomous organelles, essential for many fundamental cellular processes, including energy production, metabolite synthesis, ion homeostasis, lipid metabolism and initiation of apoptotic cell death. Proper mitochondrial physiology is a prerequisite for health and survival. Generation of new and removal of damaged or unwanted mitochondria are tightly controlled processes that need to be accurately coordinated for the maintenance of mitochondrial and cellular homeostasis...
April 28, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28461101/brain-source-localization-of-mmn-and-p300-erps-in-mild-cognitive-impairment-and-alzheimer-s-disease-a-high-density-eeg-approach
#18
Anthoula C Tsolaki, Vasiliki Kosmidou, Ioannis Yiannis Kompatsiaris, Chrysa Papadaniil, Leontios Hadjileontiadis, Aikaterini Adam, Magda Tsolaki
Alzheimer's disease is the most common neurodegenerative disease of Western societies, suggesting the need for early diagnosis, even in preclinical stages. In this vein, the localization of neuronal generators of event-related potential (ERP) components, that is, the mismatch negativity and the P300, based on high-density electroencephalogram data, was explored as a means to enhance their sensitivity as markers of preclinical Alzheimer's disease (AD). A 2-tone oddball experiment was conducted, involving 21 healthy elderly, 21 mild cognitive impairment, and 21 mild AD patients, while high-density electroencephalogram data were recorded...
March 29, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28459771/feasibility-of-hip-fracture-surgery-using-a-no-transfusion-protocol-in-elderly-patients-a-propensity-score-matched-cohort-study
#19
Byung-Ho Yoon, Young Seung Ko, Suk-Hwan Jang, Jeong Ku Ha
OBJECTIVES: This study aimed To determine whether hip fracture surgery (HFS) without transfusion affects postoperative mortality and complications in elderly patients. DESIGN: Retrospective comparative study. PATIENTS: 314 patients aged ≥ 65 years of age who underwent HFS between May 2003 and December 2014. Patients were divided into two groups: those who consented to blood transfusion if needed and those who did not. One-to-one propensity score matching generated 50 matched pairs of patients...
April 25, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28452003/the-public-health-impact-of-the-so-called-fluad-effect-on-the-2014-2015-influenza-vaccination-campaign-in-italy-ethical-implications-for-health-care-workers-and-health-communication-practitioners
#20
Roberto Rosselli, Mariano Martini, Nicola Luigi Bragazzi, Abdulla Watad
Seasonal influenza, causing complications, hospitalizations and deaths, generates a serious socio-economic burden, especially among elderly and high-risk subjects, as well as among adult individuals. Despite the availability and active free-of charge offer of influenza vaccines, vaccine coverage rates remain low and far from the target established by the Ministry of Health. Notwithstanding their effectiveness, vaccines are victims of prejudices and false myths, that contribute to the increasing phenomenon of vaccine hesitancy and loss of confidence...
April 28, 2017: Advances in Experimental Medicine and Biology
keyword
keyword
60505
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"