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https://www.readbyqxmd.com/read/29458197/changes-in-motor-function-cognition-and-emotion-related-behavior-after-right-hemispheric-intracerebral-hemorrhage-in-various-brain-regions-of-mouse
#1
Wei Zhu, Yufeng Gao, Jieru Wan, Xi Lan, Xiaoning Han, Shanshan Zhu, Weidong Zang, Xuemei Chen, Wendy Ziai, Daniel F Hanley, Scott J Russo, Ricardo E Jorge, Jian Wang
Intracerebral hemorrhage (ICH) is a detrimental type of stroke. Mouse models of ICH, induced by collagenase or blood infusion, commonly target striatum, but not other brain sites such as ventricular system, cortex, and hippocampus. Few studies have systemically investigated brain damage and neurobehavioral deficits that develop in animal models of ICH in these areas of the right hemisphere. Therefore, we evaluated the brain damage and neurobehavioral dysfunction associated with right hemispheric ICH in ventricle, cortex, hippocampus, and striatum...
February 16, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29458115/effect-of-acek-acesulfame-potassium-on-brain-function-under-dietary-restriction-in-mice
#2
Daisuke Ibi, Fumika Suzuki, Masayuki Hiramatsu
People preferably take zero or low-calorie beverages and foods with artificial sweeteners even though it has been recently suggested that long-term artificial sweetener use affects physiological functions. In addition, a lower body weight was considered to be more healthful, but an abnormally low body weight caused by an excessive diet has been reported to cause health problems. Acesulfame potassium (AceK) is one of the most commonly used for foods and beverages because of its resistance to thermal degradation and marked sweetness...
February 16, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29458098/spermine-protects-from-lps-induced-memory-deficit-via-bdnf-and-trkb-activation
#3
Pâmella K Frühauf-Perez, Fernanda R Temp, Micheli M Pillat, Cristiane Signor, Arithane Lorena Wendel, Henning Ulrich, Carlos F Mello, Maribel A Rubin
Lipopolysaccharide (LPS) has been long known to promote neuroinflammation and learning and memory deficits. Since spermine, one of the main natural polyamines in the central nervous system, protects from LPS-induced memory deficit by a mechanism that comprises GluN2B receptors, the aim of the present study was to determine whether brain-derived neurotrophic factor (BDNF), tropomyosin-related kinase B (TrkB) receptor and cAMP response element binding (CREB) are involved in this protective effect of spermine...
February 16, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29458097/topographical-memory-analyzed-in-mice-using-the-hamlet-test-a-novel-complex-maze
#4
Lucie Crouzier, Damien Gilabert, Mireille Rossel, Françoise Trousse, Tangui Maurice
The Hamlet test is an innovative device providing a complex environment for testing topographic memory in mice. Animals were trained in groups for weeks in a small village with a central agora, streets expanding from it towards five functionalized houses, where they can drink, eat, hide, run, interact with a stranger mouse. Memory was tested by depriving mice from water or food and analyzing their ability to locate the Drink/Eat house. Exploration and memory were analysed in different strains, gender, and after different training periods and delays...
February 16, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29457997/detection-of-acute-and-long-term-effects-of-concussion-dual-task-gait-balance-control-vs-computerized-neurocognitive-test
#5
David R Howell, Louis R Osternig, Li-Shan Chou
OBJECTIVE: Our aim was to examine the acute (within 72 hours of injury) and long-term (2 months post-injury) independent associations between objective dual-task gait balance and neurocognitive measurements among adolescents and young adults with a concussion and matched controls. DESIGN: Longitudinal case-control SETTING: Motion analysis laboratory PARTICIPANTS: Participants who sustained a concussion underwent a dual-task gait analysis and computerized neurocognitive testing within 72 hours of injury and again 2 months later...
February 16, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29457601/influences-of-combined-traffic-noise-on-the-ability-of-learning-and-memory-in-mice
#6
Guo-Qing Di, Zhao-Qi Qin
Objective: The present study aimed to evaluate the influences of combined traffic noise (CTN) on the ability of learning and memory in mice. Materials and Methods: The Institute of Cancer Research (ICR) mice were exposed to CTN from highways and high-speed railways for 42 days, whose day-night equivalent continuous A-weighted sound pressure level (Ldn ) was 70 dB(A). On the basis of behavioral reactions in Morris water maze (MWM) and the concentrations of amino acid neurotransmitters in the hippocampus, the impacts of CTN on learning and memory in mice were examined...
January 2018: Noise & Health
https://www.readbyqxmd.com/read/29457541/can-implicit-measures-detect-source-information-in-crime-related-amnesia
#7
Ivan Mangiulli, Tiziana Lanciano, Marko Jelicic, Kim van Oorsouw, Fabiana Battista, Antonietta Curci
Participants who are asked to simulate amnesia for a mock crime have a weaker memory for this event when they have to give up their role as a feigner, than those who are not asked to feign memory loss. According to the source monitoring framework (SMF), this memory-undermining effect of simulating amnesia for a crime would be due to misattribution of the right source of information. However, we know that the content of self-generated information (e.g., feigned version of the crime) might be preserved and recognised over time as a result of elaborative cognitive processing...
February 18, 2018: Memory
https://www.readbyqxmd.com/read/29457377/pseudohalide-induced-2d-ch-3-nh-3-2-pbi-2-scn-2-perovskite-for-ternary-resistive-memory-with-high-performance
#8
Xue-Feng Cheng, Xiang Hou, Jin Zhou, Bi-Jun Gao, Jing-Hui He, Hua Li, Qing-Feng Xu, Na-Jun Li, Dong-Yun Chen, Jian-Mei Lu
Recently, organic-inorganic hybrid perovskites (OIHP) are studied in memory devices, but ternary resistive memory with three states based on OIHP is not achieved yet. In this work, ternary resistive memory based on hybrid perovskite is achieved with a high device yield (75%), much higher than most organic ternary resistive memories. The pseudohalide-induced 2D (CH3 NH3 )2 PbI2 (SCN)2 perovskite thin film is prepared by using a one-step solution method and fabricated into Al/perovskite film/indium-tin oxide (glass substrate as well as flexible polyethylene terephthalate substrate) random resistive access memory (RRAM) devices...
February 19, 2018: Small
https://www.readbyqxmd.com/read/29457220/event-related-potentials-of-emotional-and-neutral-memories-the-role-of-encoding-position-and-delayed-testing
#9
Janine Wirkner, Carlos Ventura-Bort, Paul Schulz, Alfons O Hamm, Mathias Weymar
Previous research found that memory is not only better for emotional information but also for neutral information that has been encoded in the context of an emotional event. In the present ERP study, we investigated two factors that may influence memory for neutral and emotional items: temporal proximity between emotional and neutral items during encoding, and retention interval (immediate vs. delayed). Forty-nine female participants incidentally encoded 36 unpleasant and 108 neutral pictures (36 neutral pictures preceded an unpleasant picture, 36 followed an unpleasant picture, and 36 neutral pictures were preceded and followed by neutral pictures) and participated in a recognition memory task either immediately (N = 24) or 1 week (N = 25) after encoding...
February 19, 2018: Psychophysiology
https://www.readbyqxmd.com/read/29457149/working-memory-training-in-adolescents-decreases-laboratory-risk-taking-in-the-presence-of-peers
#10
Gail M Rosenbaum, Morgan A Botdorf, Jamie L Patrianakos, Laurence Steinberg, Jason M Chein
Adolescence is a period of heightened risk-taking relative to both adulthood and childhood, due in part to peers' increased influence on adolescent decision making. Because adolescents' choices have harmful consequences, there is great interest in specific interventions that might attenuate risk taking. We hypothesized that it might be possible to reduce adolescent risk taking through an intervention targeting the ability/tendency to engage cognitive control processes. While some studies of Working Memory Training (WMT) have indicated subsequent enhancement of adults' cognitive control abilities, potential impacts on adolescent cognitive control have not been explored...
December 2017: Journal of Cognitive Enhancement
https://www.readbyqxmd.com/read/29456645/influence-of-exposure-to-nicotine-during-pregnancy-on-the-learning-and-memory-for-adult-offspring
#11
Xing-Dui Ma, Bei-Ping Li, Yuan Han, Yun-Ping Tian, Liang Wu, Hang Wang
We aimed to investigate the indirect influence of exposure to nicotine during pregnancy on the learning and memory of adult offspring mice. Thirty pregnant C57 mice were randomly divided into either the control group (CON) or the nicotine group (NIC), with 15 mice each. The CON group was given access to drug-free water, and the NIC group was given 60 g/ml nicotine in drinking water. Sixteen adult mice were randomly selected from the 8 litters for Morris water maze test. The level of products of related factors in the hippocampus of mice in the NIC and the CON groups were compared using the1 H-MRS method...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29456359/comparison-of-computerized-and-standard-cognitive-test-in-thai-memory-clinic
#12
Pornpatr A Dharmasaroja, Disya Ratanakorn, Samart Nidhinandana, Thammanard Charernboon
Background: Computer-based Thai Cognitive Test or Computer-based Thai Mental State Examination (cTMSE) was developed aiming to help doctors to easily get the accurate results of TMSE in a routine, busy outpatient clinics. The purpose of this study was to compare the evaluation process in terms of feasibility, duration of the test, participants/administrator preference, and the results of cognitive test between cTMSE and the standard Thai Mental State Examination (sTMSE). Methods: Twenty-two elderly participants (>60 years old) who were not demented and 22 patients with mild-to-moderate dementia were included in the study...
January 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29456127/neurocognitive-disorder-in-hypertensive-patients-heart-brain-study
#13
A Vicario, G H Cerezo, M Del Sueldo, J Zilberman, S M Pawluk, N Lódolo, A E De Cerchio, R M Ruffa, R Plunkett, M E Giuliano, P Forcada, S Hauad, R Flores
The relation between hypertension and cognitive impairment is an undisputable fact. The aims of this study were to determine the prevalence of cognitive impairment in hypertensive patients, to identify the most affected cognitive domain, and to observe the association with different parameters of hypertension and other vascular risk factors. A multicentre study was carried out, and 1281 hypertensive patients of both genders and ≥21 years of age were included. Data on the following parameters were obtained: cognitive status (Minimal Cognitive Examination), behavioural status (Hospital Anxiety and Depression Scale), blood pressure, anthropometry, and biochemical profile...
February 15, 2018: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/29455394/culture-in-embryonic-kidney-serum-and-xeno-free-media-as-renal-cell-carcinoma-and-renal-cell-carcinoma-cancer-stem-cells-research-model
#14
Krzysztof M Krawczyk, Damian Matak, Lukasz Szymanski, Cezary Szczylik, Camillo Porta, Anna M Czarnecka
The use of fetal bovine serum hinders obtaining reproducible experimental results and should also be removed in hormone and growth factor studies. In particular hormones found in FBS act globally on cancer cell physiology and influence transcriptome and metabolome. The aim of our study was to develop a renal carcinoma serum free culture model optimized for (embryonal) renal cells in order to select the best study model for downstream auto-, para- or endocrine research. Secondary aim was to verify renal carcinoma stem cell culture for this application...
February 17, 2018: Cytotechnology
https://www.readbyqxmd.com/read/29455170/comparison-and-validation-of-screening-tools-for-substance-use-in-pregnancy-a-cross-sectional-study-conducted-in-maryland-prenatal-clinics
#15
Victoria H Coleman-Cowger, Emmanuel A Oga, Erica N Peters, Kathleen Trocin, Bartosz Koszowski, Katrina Mark
INTRODUCTION: Prescription-drug use in the USA has increased by more than 60% in the last three decades. Prevalence of prescription-drug use among pregnant women is currently estimated around 50%. Prevalence of illicit drug use in the USA is 14.6% among pregnant adolescents, 8.6% among pregnant young adults and 3.2% among pregnant adults. The first step in identifying problematic drug use during pregnancy is screening; however, no specific substance-use screener has been universally recommended for use with pregnant women to identify illicit or prescription-drug use...
February 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29455082/evaluating-subjective-cognitive-impairment-in-the-adult-epilepsy-clinic-effects-of-depression-number-of-antiepileptic-medications-and-seizure-frequency
#16
Lauren Feldman, Brittany Lapin, Robyn M Busch, Jocelyn F Bautista
OBJECTIVE: Subjective cognitive complaints are a frequent concern of patients with epilepsy. The Aldenkamp-Baker Neuropsychological Assessment Schedule (ABNAS) is a patient-reported scale validated to measure adverse cognitive effects of antiepileptic drugs (AEDs). The goals of this study were to identify predictors of patient-reported cognitive dysfunction and to assess the relationship between subjective and objective cognitive impairment. METHODS: The Cleveland Clinic Knowledge Program Data Registry was used to identify adult patients seen in outpatient epilepsy clinic from January to May 2015 and who completed the following scales: ABNAS for subjective cognitive impairment, Patient Health Questionnaire (PHQ-9) for depression, Generalized Anxiety Disorder 7-item (GAD-7) scale, Quality of Life in Epilepsy (QOLIE-10), and EuroQOL five dimensions questionnaire (EQ-5D) for health-related quality of life...
February 15, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29455002/the-possible-neuroprotective-effect-of-ellagic-acid-on-sodium-arsenate-induced-neurotoxicity-in-rats
#17
Mehdi Goudarzi, Shivasadat Amiri, Ali Nesari, Azam Hosseinzadeh, Esrafil Mansouri, Saeed Mehrzadi
OBJECTIVE: Arsenic is a well-known environmental contaminant, causing toxicity in different organs. The aim of this study was to investigate the possible neuroprotective effect of ellagic acid (EA) on arsenic-induced neurotoxicity in rats. DESIGN: Animals were divided into five groups. The first group received normal saline (2 ml/kg) for 21 days as control group. Group 2 was orally treated with sodium arsenite (SA, 10 mg/kg) for 21 days. Groups 3 and 4 were orally treated with SA (10 mg/kg) for 7 days prior to EA (10 and 30 mg/kg respectively) treatment and continued up to 21 days simultaneously with SA administration...
February 15, 2018: Life Sciences
https://www.readbyqxmd.com/read/29454895/ensemble-coding-of-face-identity-is-present-but-weaker-in-congenital-prosopagnosia
#18
Matthew Robson, Romina Palermo, Linda Jeffery, Markus F Neumann
Individuals with congenital prosopagnosia (CP) are impaired at identifying individual faces but do not appear to show impairments in extracting the average identity from a group of faces (known as ensemble coding). However, possible deficits in ensemble coding in a previous study (CPs n=4) may have been masked because CPs relied on pictorial (image) cues rather than identity cues. Here we asked whether a larger sample of CPs (n=11) would show intact ensemble coding of identity when availability of image cues was minimised...
February 15, 2018: Neuropsychologia
https://www.readbyqxmd.com/read/29454881/curcumin-treatment-leads-to-better-cognitive-and-mood-function-in-a-model-of-gulf-war-illness-with-enhanced-neurogenesis-and-alleviation-of-inflammation-and-mitochondrial-dysfunction-in-the-hippocampus
#19
M Kodali, B Hattiangady, G A Shetty, A Bates, B Shuai, A K Shetty
Diminished cognitive and mood function are among the most conspicuous symptoms of Gulf WarIllness(GWI). Our previous studies in a rat model of GWI have demonstrated that persistent cognitive and mood impairments are associated with substantially declined neurogenesis, chronic low-grade inflammation, increased oxidative stress and mitochondrial dysfunction in the hippocampus. We tested the efficacy of curcumin (CUR) to maintain better cognitive and mood function in a rat model of GWI because of its neurogenic, antiinflammatory, antioxidant, and memory and mood enhancing properties...
February 15, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29454265/supplementation-of-lycopene-attenuates-lipopolysaccharide-induced-amyloidogenesis-and-cognitive-impairments-via-mediating-neuroinflammation-and-oxidative-stress
#20
Jia Wang, Lixia Li, Zhuo Wang, Yifan Cui, Xintong Tan, Tian Yuan, Qian Liu, Zhigang Liu, Xuebo Liu
Neuroinflammation is documented to be the major culprit of Alzheimer's disease. Lycopene (LYC), a fat soluble carotenoid, exhibits neuroprotective function in several neurodegenerative disorders. However, the effects of LYC to countering systemic inflammation-induced amyloidogenesis and memory deficiency remain to be elucidated. In current study, 3-month-old male C57BL/6J mice were treated with 0.03% LYC (w/w, mixed into normal chow) for 5 weeks. The mice were then treated by intraperitoneal injection of LPS (0...
February 2, 2018: Journal of Nutritional Biochemistry
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