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https://www.readbyqxmd.com/read/29245083/concordance-between-the-wada-test-and-neuroimaging-lateralization-influence-of-imaging-modality-fmri-and-meg-and-patient-experience
#1
Steven Kemp, Garreth Prendergast, Theodoros Karapanagiotidis, Gus Baker, Thomas P Kelly, Tufail Patankar, Simon S Keller
The Wada test remains the traditional test for lateralizing language and memory function prior to epilepsy surgery. Functional imaging, particularly functional MRI (fMRI), has made progress in the language domain, but less so in the memory domain. Magnetoencephalography (MEG) has received less research attention, but shows promise, particularly for language lateralization. We recruited a consecutive sample of 19 patients with epilepsy who had completed presurgical work-up, including the Wada test, and compared fMRI (memory) and MEG (language and memory) with Wada test results...
December 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29244894/the-concealed-information-test-is-susceptible-to-misleading-information
#2
Katja Volz, Lisa-Marie Bahr, Markus Heinrichs, Dieter Vaitl, Wolfgang Ambach
An approach toward detecting hidden knowledge is the Concealed Information Test (CIT). It relies on the memory of crime-relevant information. This study investigated whether its validity is susceptible to memory distortion by misleading information. A misleading information paradigm was employed to distort memory prior to an interrogation with a CIT. Forty-one participants watched a video with specific crime-related information. After a 1-week retention interval, misleading information was introduced. Afterward, a CIT was performed, followed by a threefold memory test...
December 15, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29244847/cognitive-failures-in-late-adulthood-the-role-of-age-social-context-and-depressive-symptoms
#3
Paul Kenneth Hitchcott, Maria Chiara Fastame, Dalila Langiu, Maria Pietronilla Penna
The incidence of self-reported cognitive failures among older adults may be an index of successful cognitive aging. However, self-reported cognitive failures are biased by variation in depressive symptomatology. This study examined age-related and socio-cultural context effects on cognitive failures while controlling for depressive symptoms. Both overall and specific factors of cognitive failures were determined. A further goal was to investigate the relationship between working memory and cognitive efficiency measures and cognitive failures...
2017: PloS One
https://www.readbyqxmd.com/read/29244638/memory-contextualization-the-role-of-prefrontal-cortex-in-functional-integration-across-item-and-context-representational-regions
#4
Wei Zhang, Vanessa A van Ast, Floris Klumpers, Karin Roelofs, Erno J Hermans
Memory recall is facilitated when retrieval occurs in the original encoding context. This context dependency effect likely results from the automatic binding of central elements of an experience with contextual features (i.e., memory "contextualization") during encoding. However, despite a vast body of research investigating the neural correlates of explicit associative memory, the neural interactions during encoding that predict implicit context-dependent memory remain unknown. Twenty-six participants underwent fMRI during encoding of salient stimuli (faces), which were overlaid onto unique background images (contexts)...
December 15, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/29244611/learning-new-letter-like-writing-patterns-explicitly-and-implicitly-in-children-and-adults
#5
M Jongbloed-Pereboom, A Overvelde, M W G Nijhuis-van der Sanden, B Steenbergen
A handwriting task was used to test the assumption that explicit learning is dependent on age and working memory, while implicit learning is not. The effect of age was examined by testing both, typically developing children (5-12 years old, n = 81) and adults (n = 27) in a counterbalanced within-subjects design. Participants were asked to repeatedly write letter-like patterns on a digitizer with a non-inking pen. Reproduction of the pattern was better after explicit learning compared to implicit learning. Age had positive effects on both explicit and implicit learning; working memory did not affect learning in either conditions...
December 15, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/29244542/differential-long-term-medication-impact-on-executive-function-and-delay-aversion-in-adhd
#6
Belen Rubio Morell, Sergio Hernández Expósito
The objective was to compare long-term effects of methylphenidate (MPH) and atomoxetine (ATX) on executive functions (EF) and delay aversion (DAv) in ADHD. A randomized controlled trial was conducted. A comprehensive neuropsychological battery was administered at three moments (Naive, Post-1, Post-2). ADHD participants who showed deficits in the naive evaluation (n = 26) were randomized to receive either MPH (n = 13; Mage = 11 ± 1, MIQ 96 ± 8) or ATX (n = 13; Mage = 10 ± 1, MIQ 106 ± 16...
December 15, 2017: Applied Neuropsychology. Child
https://www.readbyqxmd.com/read/29244170/sleep-deprivation-triggers-cognitive-control-impairments-in-task-goal-switching
#7
Hichem Slama, Daphne Olivia Chylinski, Gaétane Deliens, Rachel Leproult, Rémy Schmitz, Philippe Peigneux
Study objectives: This study investigates the impact of sleep deprivation (SD) on task-goal switching, a key component of cognitive flexibility. Methods: Task-goal switching performance was tested after one night of regular sleep (n = 17 participants) or of total SD (n = 18). To understand the relationships between task-switching performance and other cognitive processes following SD, participants were tested for other key attentional (alertness and vigilance) and executive (inhibition and working memory) functions...
December 13, 2017: Sleep
https://www.readbyqxmd.com/read/29243862/effects-of-sodium-benzoate-a-commonly-used-food-preservative-on-learning-memory-and-oxidative-stress-in-brain-of-mice
#8
Mohammad Javad Khoshnoud, Asma Siavashpour, Mojgan Bakhshizadeh, Marzieh Rashedinia
Sodium benzoate (SB) is a widely used preservative and antimicrobial substance in many foods and soft drinks. However, this compound is generally recognized as safe food additives, but evidence has suggested that a high intake of SB may link to attention deficit-hyperactivity disorder in children. Present study investigate the effects of oral administration of different concentrations of SB (0.56, 1.125, and 2.25 mg/mL) for 4 weeks, on the learning and memory performance tests, and also the levels of malondialdehyde (MDA), reduced glutathione (GSH), and acetylcholinesterase activity (AChE) in the mouse brain...
December 15, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/29243543/a-kainate-receptor-gluk4-deletion-protective-against-bipolar-disorder-is-associated-with-enhanced-cognitive-performance-across-diagnoses-in-the-twinsuk-cohort
#9
Maria Koromina, Miles Flitton, Ian Mellor, Helen Miranda Knight
OBJECTIVES: Cognitive deficits are a common feature of neuropsychiatric disorders. We investigated the relationship between cognitive performance and a deletion allele within GluK4 protective against risk for bipolar disorder, in 1642 individuals from the TwinsUK study. METHODS: Cognitive performance was assessed using the National Adult Reading Test, four CANTAB tests (Spatial Working Memory, Paired Associates Learning, Pattern Recognition Memory, and Reaction Time), and two Principal Component Analysis derived factors...
December 15, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/29243518/synaesthesia-is-linked-to-more-vivid-and-detailed-content-of-autobiographical-memories-and-less-fading-of-childhood-memories
#10
Taylor Chin, Jamie Ward
People with synaesthesia have enhanced memory on a wide range of laboratory tests of episodic memory, but very little is known about their real-world memory. This study used a standard measure of autobiographical remembering (the Autobiographical Memory Questionnaire, AMQ) considering four constructs (Recollection, Belief, Impact and Rehearsal) and two time periods (recent memories from adulthood, remote memories from childhood). Synaesthetes reported more Recollection (e.g., sensory detail) and Belief (e.g...
December 15, 2017: Memory
https://www.readbyqxmd.com/read/29242410/adiposity-and-cortisol-response-to-stress-in-indian-adolescents
#11
G V Krishnaveni, A Jones, S R Veena, R Somashekara, S C Karat, C H D Fall
OBJECTIVE: Greater adiposity is a risk factor for altered hypothalamic-pituitary-adrenal axis reactivity to stress. We examined associations of different adiposity measures with cortisol responses during the Trier Social Stress Test for children (TSST-C). DESIGN: Cohort study. SETTING: Holdsworth Memorial Hospital, Mysore, India. PARTICIPANTS: Adolescents aged 13.5y from a birth cohort were recruited (N=269, 133 boys)...
December 14, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29241675/effect-of-telmisartan-on-preventing-learning-and-memory-deficits-via-peroxisome-proliferator-activated-receptor-%C3%AE-in-vascular-dementia-spontaneously-hypertensive-rats
#12
Yuan Gao, Wei Li, Yali Liu, Yan Wang, Jianchao Zhang, Miao Li, Mengsen Bu
BACKGROUND: This study aimed to explore the effect of telmisartan (TEL), as a partial peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist, in vascular dementia (VaD) rats induced by middle cerebral artery occlusion (MCAO). METHODS: Spontaneously hypertensive rats were divided into 6 groups: the sham group, model group, TEL-treated groups (1, 5, and 10 mg/kg), and TEL + GW9662 (10 mg/kg + 1 mg/kg). Using the MCAO method established the VaD rat model...
December 11, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29241652/acute-administration-of-roflumilast-enhances-immediate-recall-of-verbal-word-memory-in-healthy-young-adults
#13
M A Van Duinen, A Sambeth, P R A Heckman, S Smit, M Tsai, G Lahu, T Uz, A Blokland, J Prickaerts
The need for new and effective treatments for dementia remains indisputably high. Phosphodiesterase inhibitors (PDE-Is) have proven efficacy as cognitive enhancers based on their positive effects in numerous preclinical studies. Especially the PDE4 subfamily is of interest due to its expression in the hippocampus, the key structure for memory formation. The current study investigates the memory enhancing effects of the clinically approved PDE4-I roflumilast in a test battery including the Verbal Learning Task (VLT) combined with electroencephalography (EEG) recording...
December 11, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29241126/the-chronic-exposure-to-abamectin-causes-spatial-memory-deficit-and-depressive-behavior-in-mice
#14
Wellington Alves Mizael da Silva, Abraão Tiago Batista Guimarães, Mateus Flores Montalvão, Bruna de Oliveira Mendes, Aline Sueli de Lima Rodrigues, Guilherme Malafaia
It is known that abamectin (ABA), which is a component belonging to the group of avermectins, has been broadly used as biopesticide. Although its effect on non-target aquatic organisms is known, knowledge about its impacts on terrestrial animals such as mammals remains incipient. Thus, we aim at investigating the effects (phycical and neural-behavioral) from the chronic exposure (90 days) to ABA (1/10 of LD50) on Swiss and C57Bl/6J mice from both sexes. Accordingly, at the end of the experimental period the animals were subjected to the following tests: Novel Object Recognition Test (NORT), Morris Water Maze (MWM), Tail Suspension Test (TST), and Forced Swimming Test (FST)...
December 7, 2017: Chemosphere
https://www.readbyqxmd.com/read/29241082/the-effect-of-n-acetylcysteine-and-working-memory-training-on-cocaine-use-craving-and-inhibition-in-regular-cocaine-users-correspondence-of-lab-assessments-and-ecological-momentary-assessment
#15
Mieke H J Schulte, Reinout W Wiers, Wouter J Boendermaker, Anna E Goudriaan, Wim van den Brink, Denise S van Deursen, Malte Friese, Emily Brede, Andrew J Waters
INTRODUCTION: Effective treatment for cocaine use disorder should dampen hypersensitive cue-induced motivational processes and/or strengthen executive control. Using a randomized, double-blind, placebo-controlled intervention, the primary aim of this study was to investigate the effect of N-Acetylcysteine (NAC) and working memory (WM)-training to reduce cocaine use and craving and to improve inhibition assessed in the laboratory and during Ecological Momentary Assessment (EMA). The second aim was to examine correspondence between laboratory and EMA data...
December 11, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29241013/libreta-computerized-optimization-and-code-synthesis-for-electron-repulsion-integral-evaluation
#16
Jun Zhang
A new library called LIBRETA for the evaluation of electron repulsion integrals (ERIs) and their first and second derivatives over segmented and contracted Gaussian functions is developed. Our LIBRETA is optimized from three aspects: (1) The Obara-Saika, Dupuis-Rys-King, and McMurchie-Davidson method are all employed. The recurrence relations involved are optimized by tree-search for each combination of angular momenta, and in the best case, 50% of the intermediates can be eliminated to reduce the computational cost...
December 14, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29240950/what-did-you-do-today-variability-in-daily-activities-is-related-to-variability-in-daily-cognitive-performance
#17
Allison A M Bielak, Jacqueline Mogle, Martin J Sliwinski
Objectives: Are the activities we do each day related to fluctuations in our daily cognitive performance? Positive longitudinal associations between cognitive, physical, and social activities and cognitive ability in adulthood are well established. However little is known about how this relationship may operate at the daily level. Methods: Community-dwelling participants 60-90 years of age (M = 69.41; n = 146) reported their activity participation and completed cognitive tests online for 7 consecutive days...
December 12, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29240855/lawrence-transfer-factor-transference-of-specifc-immune-memory-by-dialyzable-leukocyte-extract-from-a-cd8-t-cell-line
#18
Jason F Wang, Andrew J Park, Tina Rendini, William R Levis
<p>Lawrence transfer factor (TF) is defned as dialyzable leukocyte extract (DLE) that can transfer antigen-specifc cell-mediated immunity from a person testing positive for the antigen in a delayed type hypersensitivity skin test manner to a person negative for the same antigen.</p> <p>A recent article by Myles et al1 has identifed a DLE isolated from an established CD8+ T cell line capable of transferring antigen-specifc immunity. The DLE contains a portion of the beta chain of the T cell receptor and additional nucleotide and protein factors that are being subjected to further modern biochemical analysis...
December 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29240561/version-3-of-the-alzheimer-disease-centers-neuropsychological-test-battery-in-the-uniform-data-set-uds
#19
Sandra Weintraub, Lilah Besser, Hiroko H Dodge, Merilee Teylan, Steven Ferris, Felicia C Goldstein, Bruno Giordani, Joel Kramer, David Loewenstein, Dan Marson, Dan Mungas, David Salmon, Kathleen Welsh-Bohmer, Xiao-Hua Zhou, Steven D Shirk, Alireza Atri, Walter A Kukull, Creighton Phelps, John C Morris
INTRODUCTION: The neuropsychological battery of the Uniform Data Set (UDSNB) was implemented in 2005 by the National Institute on Aging (NIA) Alzheimer Disease Centers program to measure cognitive performance in dementia and mild cognitive impairment due to Alzheimer Disease. This paper describes a revision, the UDSNB 3.0. METHODS: The Neuropsychology Work Group of the NIA Clinical Task Force recommended revisions through a process of due diligence to address shortcomings of the original battery...
December 13, 2017: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/29240340/update-on-current-care-guideline-memory-disorders
#20
(no author information available yet)
Any complaint about memory should be examined. Diagnosis is based on international criteria. Basic evaluation consists of medical history, clinical evaluation, cognitive tests and brain imaging. When a diagnosis of Alzheimer's disease (AD), AD with cerebrovascular disease or with Lewy Body disease (LBD), or Dementia associated with Parkinson's disease or LBD is made, evidence-based medical therapy (acetylcholine esterase inhibitor or memantine) is indicated as a part of comprehensive care. In frontotemporal degenerations, these drugs are ineffective...
2017: Duodecim; Lääketieteellinen Aikakauskirja
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