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https://www.readbyqxmd.com/read/28110486/spectra-optia-%C3%A2-for-automated-red-blood-cell-exchange-in-patients-with-sickle-cell-disease-a-nice-medical-technology-guidance
#1
REVIEW
Iain Willits, Helen Cole, Roseanne Jones, Kimberley Carter, Mick Arber, Michelle Jenks, Joyce Craig, Andrew Sims
The Spectra Optia(®) automated apheresis system, indicated for red blood cell exchange in people with sickle cell disease, underwent evaluation by the National Institute for Health and Care Excellence, which uses its Medical Technologies Advisory Committee to make recommendations. The company (Terumo Medical Corporation) produced a submission making a case for adoption of its technology, which was critiqued by the Newcastle and York external assessment centre. Thirty retrospective observational studies were identified in their clinical submission...
January 21, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28110410/neurophysiological-assessment-of-brain-dysfunction-in-critically-ill-patients-an-update
#2
REVIEW
Eric Azabou, Catherine Fischer, Jean Michel Guerit, Djillali Annane, François Mauguiere, Fréderic Lofaso, Tarek Sharshar
The aim of this review was to provide up-to-date information about the usefulness of clinical neurophysiology testing in the management of critically ill patients. Evoked potentials (EPs) and electroencephalogram (EEG) are non-invasive clinical neurophysiology tools that allow an objective assessment of the central nervous system's function at the bedside in intensive care unit (ICU). These tests are quite useful in diagnosing cerebral complications, and establishing the vital and functional prognosis in ICU...
January 21, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28110176/the-management-of-hiv-in-pregnancy-a-10-year-experience
#3
Sonia F Raffe, Charlotte Savage, Louisa A Perry, Amie Patel, Tricia Keith, Richard Howell, Robert Bradley, Rob Bomont, Katy Fidler, Yvonne Gilleece
OBJECTIVE: The package of care to reduce HIV mother to child transmission (MTCT) has evolved significantly since trials of ante and intrapartum antiretroviral therapy (ART) in 1994. In the UK MTCT rate has fallen from 25.6% in the 1990s to 0.46%. We review the management of HIV in pregnancy in Brighton in the context of evolving guidelines. STUDY DESIGN: HIV, obstetric and neonatal notes of all HIV positive women, pregnant between 2003 and 2014, were reviewed. RESULTS: 97 pregnancies in 75 women were identified, resulting in 79 live births...
January 3, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28110031/interspinous-process-devices-ipd-alone-versus-decompression-surgery-for-lumbar-spinal-stenosis-lss-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#4
REVIEW
Xing-Wen Zhao, Jian-Xiong Ma, Xin-Long Ma, Fei Li, Wei-Wei He, Xuan Jiang, Yin Wang, Biao Han, Bin Lu
BACKGROUND: and purpose: Interspinous process devices (IPD) were widely used for the treatment of lumbar spinal stenosis (LSS). However, whether IPD was superior to bony decompression was still debated. We aimed to compare the clinical outcomes of IPD to bony decompression for LSS. METHODS: PubMed, Cochrane library, Cochrane Central Register of Controlled Trials (CCTR), Ovid Medline, China national knowledge internet database, Wan Fang database were searched in August...
January 18, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28109998/impact-of-mean-arterial-pressure-on-clinical-outcomes-in-comatose-survivors-of-out-of-hospital-cardiac-arrest-insights-from-the-university-of-ottawa-heart-institute-regional-cardiac-arrest-registry-capital-care
#5
Juan J Russo, Tyler E James, Benjamin Hibbert, Altayyeb Yousef, Christina Osborne, George A Wells, Michael P V Froeschl, Derek Y So, Aun Yeong Chong, Marino Labinaz, Chris A Glover, Jean-François Marquis, Alexander Dick, Jordan Bernick, Michel R Le May
AIM: of the study We sought to assess the relationship between mean arterial pressure (MAP) and clinical outcomes in comatose survivors of out-of-hospital cardiac arrest (OHCA). METHODS: We identified consecutive comatose survivors of OHCA with an initial shockable rhythm treated with targeted temperature management. We examined clinical outcomes in relation to mean MAP (measured hourly) during the first 96hours of hospitalization. Mean MAP was examined as both a continuous variable and a categorical variable consisting of 3 pre-specified strata: <70mmHg, 70 to <80mmHg, and ≥80mmHg...
January 18, 2017: Resuscitation
https://www.readbyqxmd.com/read/28109993/epilepsy-associated-levels-of-perceived-stigma-their-associations-with-treatment-and-related-factors-a-cross-sectional-study-in-urban-and%C3%A2-rural-areas-in-ecuador
#6
Jaime Luna, Mandy Nizard, Danielle Becker, Daniel Gerard, Alejandro Cruz, Voa Ratsimbazafy, Michel Dumas, Marcelo Cruz, Pierre-Marie Preux
BACKGROUND: Epilepsy is felt to be a stigmatizing condition. Stigma has been considered one of the major factors contributing to the burden of epilepsy and to the treatment gap. Stigma has a negative effect on the management of people with epilepsy (PWE). Furthermore, lack of information and inappropriate beliefs are still the factors that most contribute to stigma and discrimination. In this study, we assessed the level of perceived stigma in urban and rural areas and we report their association with in antiepileptic drug (AED) use, effects on seeking medical care, and stigma-associated factors...
January 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28109672/optimizing-follow-up-after-anatomic-total-shoulder-arthroplasty
#7
Bradley Schoch, Jean David Werthel, Cathy D Schleck, William S Harmsen, John Sperling, Joaquín Sánchez-Sotelo, Robert H Cofield
BACKGROUND: With increases in both total shoulder arthroplasty (TSA) volumes and patient life expectancies, the number of patients requiring follow-up after shoulder arthroplasty continues to grow exponentially. The purpose of this study is to establish a data-based follow-up schedule minimizing unnecessary patient and health care system costs without sacrificing patient care. METHODS: Between January 1975 and January 2013, 2786 consecutive anatomic TSAs were performed at our institution...
January 19, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28109650/development-and-evaluation-of-a-generic-education-program-for-chronic-diseases-in-childhood
#8
Gundula Ernst, Ingo Menrath, Karin Lange, Nora Eisemann, Doris Staab, Ute Thyen, Ruediger Szczepanski
OBJECTIVE: To support families with a chronically ill child, a modular curriculum and new healthcare structures (trainer education, quality management) for a group self-management program (ModuS) were developed. ModuS focuses on common psychosocial aspects of chronic conditions and comprises generic and disease-specific modules. A pilot test was conducted for asthma by comparing ModuS with an established asthma-specific education program (CAE). METHODS: Under routine care conditions, 491 children (6-17 years) with asthma and their parents participated in a multi-center prospective study (265 ModuS; 226 CAE)...
January 12, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28109570/osteopathic-manipulative-treatment-improves-heart-surgery-outcomes-a-randomized-controlled-trial
#9
Vittorio Racca, Bruno Bordoni, Paolo Castiglioni, Maddalena Modica, Maurizio Ferratini
BACKGROUND: Controlling sternal pain after heart surgery is important to reduce the risk of postoperative complications, but pain is often undertreated because of contraindications and side effects of analgesic drugs. Recently, osteopathic manipulative treatment (OMT) was demonstrated to reduce pain in different clinical contexts, suggesting its potential utility after cardiac surgery. The aim of this open-label, controlled study is to assess whether OMT contributes to sternal pain relief and improves postoperative outcomes...
January 18, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28109409/ecco-essential-requirements-for-quality-cancer-care-soft-tissue-sarcoma-in-adults-and-bone-sarcoma-a-critical-review
#10
REVIEW
Elisabeth Andritsch, Marc Beishon, Stefan Bielack, Sylvie Bonvalot, Paolo Casali, Mirjam Crul, Roberto Delgado- Bolton, Davide Maria Donati, Hassan Douis, Rick Haas, Pancras Hogendoorn, Olga Kozhaeva, Verna Lavender, Jozsef Lovey, Anastassia Negrouk, Philippe Pereira, Pierre Roca, Godelieve Rochette de Lempdes, Tiina Saarto, Bert van Berck, Gilles Vassal, Markus Wartenberg, Wendy Yared, Alberto Costa, Peter Naredi
BACKGROUND: ECCO essential requirements for quality cancer care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to patients who have a specific tumour type. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey...
February 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28109408/ecco-essential-requirements-for-quality-cancer-care-colorectal-cancer-a-critical-review
#11
REVIEW
Geerard Beets, David Sebag-Montefiore, Elisabeth Andritsch, Dirk Arnold, Marc Beishon, Mirjam Crul, Jan Willem Dekker, Roberto Delgado-Bolton, Jean-François Fléjou, Wolfgang Grisold, Geoffrey Henning, Andrea Laghi, Jozsef Lovey, Anastassia Negrouk, Philippe Pereira, Pierre Roca, Tiina Saarto, Thomas Seufferlein, Claire Taylor, Giampaolo Ugolini, Cornelis van de Velde, Bert van Herck, Wendy Yared, Alberto Costa, Peter Naredi
ECCO essential requirements for quality cancer care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to patients who have a specific tumour type. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey. References are made to clinical guidelines and other resources where appropriate, and the focus is on care in Europe...
February 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28109290/characterizing-breast-conditions-at-an-open-access-breast-clinic-in-south-africa-a-model-that-is-more-than-cancer-care-for-a-resource-limited-setting
#12
Sarah Rayne, Naomi Lince-Deroche, Cheryl Hendrickson, Kate Shearer, Faith Moyo, Pam Michelow, Grace Rubin, Carol Benn, Cynthia Firnhaber
BACKGROUND: While most breast-related research focuses on cancer, presentation of symptomatic persons in non-screened environments requires understanding the spectrum of breast diseases so as to plan services in resource-constrained settings. This study presents the variety of breast disease managed at a government, open-access breast clinic in South Africa. METHODS: We performed a retrospective file review using a systematic random sample of patients 18 years and above presenting for breast care over a 14-month period...
January 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28109275/insights-of-health-district-managers-on-the-implementation-of-primary-health-care-outreach-teams-in-johannesburg-south-africa-a-descriptive-study-with-focus-group-discussions
#13
Shabir Moosa, Anselme Derese, Wim Peersman
BACKGROUND: Primary health care (PHC) outreach teams are part of a policy of PHC re-engineering in South Africa. It attempts to move the deployment of community health workers (CHWs) from vertical programmes into an integrated generalised team-based approach to care for defined populations in municipal wards. There has little evaluation of PHC outreach teams. Managers' insights are anecdotal. METHODS: This is descriptive qualitative study with focus group discussions with health district managers of Johannesburg, the largest city in South Africa...
January 21, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28109266/team-based-care-for-improving-hypertension-management-among-outpatients-tbc-hta-study-protocol-for-a-pragmatic-randomized-controlled-trial
#14
Valérie Santschi, Grégoire Wuerzner, Arnaud Chiolero, Bernard Burnand, Philippe Schaller, Lyne Cloutier, Gilles Paradis, Michel Burnier
BACKGROUND: Blood pressure (BP) is poorly controlled among a large proportion of hypertensive outpatients. Innovative models of care are therefore needed to improve BP control. The Team-Based Care for improving Hypertension management (TBC-HTA) study aims to evaluate the effect of a team-based care (TBC) interprofessional intervention, involving nurses, community pharmacists and physicians, on BP control of hypertensive outpatients compared to usual care in routine clinical practice. METHODS/DESIGN: The TBC-HTA study is a pragmatic randomized controlled study with a 6-month follow-up which tests a TBC interprofessionnal intervention conducted among uncontrolled treated hypertensive outpatients in two ambulatory clinics and among seven nearby community pharmacies in Lausanne and Geneva, Switzerland...
January 21, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28109182/are-home-visits-an-effective-method-for-diabetes-management-a-quantitative-systematic-review-and-meta-analysis
#15
Lin Han, Yuxia Ma, Suhong Wei, Jinhui Tian, Xiaochun Yang, Xiping Shen, Jun Zhang, Yuexian Shi
AIMS: Previous reviews have revealed uncertainty regarding the effectiveness of home visit interventions for managing diabetes. Therefore, we performed a quantitative systematic review and meta-analysis to evaluate the effects of home visit interventions among patients with diabetes. METHODS: We searched various electronic databases (PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL, Wanfang, and Chinese scientific full-text databases) from their inception until March 2016...
January 21, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28108821/the-relationship-between-patient-activation-confidence-to-self-manage-side-effects-and-adherence-to-oral-oncolytics-a-pilot-study-with-michigan-oncology-practices
#16
Teresa M Salgado, Emily Mackler, Jane A Severson, Jamie Lindsay, Peter Batra, Laura Petersen, Karen B Farris
PURPOSE: The Michigan Oncology Quality Consortium (MOQC) is a continuous quality improvement collaborative seeking to improve oncology care in Michigan, including for patients taking oral chemotherapy. The aim of this study was to assess the relationship between patient activation, confidence to self-manage side effects, and adherence to oral oncolytics to inform future oncology care. METHODS: A multicenter cross-sectional observational study was conducted using an online survey to examine patient activation (patient activation measure, PAM), health literacy, symptom burden (Edmonton Symptom Assessment System, ESAS), confidence to self-manage side effects (fatigue, nausea, and diarrhea), and adherence to oral oncolytics...
January 20, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28108799/the-economics-of-stone-disease
#17
Noah E Canvasser, Peter Alken, Michael Lipkin, Stephen Y Nakada, Hiren S Sodha, Abdulkadir Tepeler, Yair Lotan
The rising prevalence of kidney stone disease is associated with significant costs to healthcare systems worldwide. This is in part due to direct procedural and medical management costs, as well as indirect costs to health systems, patients, and families. A number of manuscripts evaulating the economics of stone disease have been published since the 2008s International Consultation on Stone Disease. These highlight costs associated with stone disease, including acute management, surgical management, and medical management...
January 20, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28108642/the-potential-role-for-smartphones-among-older-adults-with-chronic-noncancer-pain-a-qualitative-study
#18
Joshua E Richardson, Jennifer I Lee, Anita Nirenberg, M Carrington Reid
: OBJECTIVE : To determine the role that smartphones may play in supporting older adults with chronic noncancer pain (CNCP) in order to improve pain management in this expanding population. DESIGN:  Qualitative study. SETTING:  One academically affiliated primary care practice serving older adults with CNCP in New York City. SUBJECTS : Thirteen older adults (age 65-85 years) with CNCP on chronic opioid therapy, that is, continuous use of opioids for at least six months...
January 20, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28108568/the-role-of-day-one-postoperative-review-of-intraocular-pressure-in-modern-vitrectomy-surgery
#19
Nicholas Brennan, Ian Reekie, Eric Ezra, Keith Barton, Ananth Viswanathan, Mahiul Mk Muqit
BACKGROUND: With the introduction of sutureless 23-gauge (23G) vitrectomy, the risks for elevated intraocular pressure (IOP) and the need for day 1 review of IOP are less certain. AIMS: To assess current practice for postoperative review in the vitreoretinal service at a large tertiary referral centre; to assess whether day 1 review detected complications altering patient management; to identify risk factors for IOP spikes postvitrectomy. METHODS: Retrospective, consecutive case note review of all patients undergoing 23G vitrectomy at the study institution between April and June 2013...
January 20, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28108319/how-the-changes-in-the-system-affect-trauma-care-provision-the-assessment-of-and-implications-for-lithuanian-trauma-service-performance-in-2007-2012
#20
Žilvinas Dambrauskas, Vytautas Aukštakalnis, Aurika Karbonskienė, Dmitrijus Kačiurinas, Jolanta Vokietienė, Robertas Lapka, Algimantas Pamerneckas, Narūnas Porvaneckas, Kęstutis Stašaitis, Nedas Jasinskas, Paulius Dobožinskas, Dinas Vaitkaitis, Raimundas Lunevičius
OBJECTIVE: The aim of this study was to identify and assess the effects of changes in the Lithuanian trauma service from 2007 to 2012. We postulate that the implications derived from this study will be of importance to trauma policy planners and makers in Lithuania and throughout other countries of Eastern and Central Europe. MATERIALS AND METHODS: Out of 10,390 trauma admissions to four trauma centers in 2007, 294 patients (2.8%) were randomly selected for the first arm of a representative study sample...
January 6, 2017: Medicina
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