keyword
https://read.qxmd.com/read/34806712/myocardial-infarction-by-percutaneous-embolization-coil-deployment-in-a-swine-model
#21
JOURNAL ARTICLE
Daina Martínez-Falguera, Edgar Fadeuilhe, Albert Teis, Julia Aranyo, Raquel Adeliño, Felipe Bisbal, Oriol Rodriguez-Leor, Carolina Gálvez-Montón
Myocardial infarction (MI) is the leading cause of mortality worldwide. Despite the use of evidence-based treatments, including coronary revascularization and cardiovascular drugs, a significant proportion of patients develop pathological left-ventricular remodeling and progressive heart failure following MI. Therefore, new therapeutic options, such as cellular and gene therapies, among others, have been developed to repair and regenerate injured myocardium. In this context, animal models of MI are crucial in exploring the safety and efficacy of these experimental therapies before clinical translation...
November 4, 2021: Journal of Visualized Experiments: JoVE
https://read.qxmd.com/read/34743564/sex-differences-in-cardiovascular-outcomes-of-older-adults-after-myocardial-infarction
#22
JOURNAL ARTICLE
Anne M Kerola, Antti Palomäki, Päivi Rautava, Maria Nuotio, Ville Kytö
Background Evidence on the impact of sex on prognoses after myocardial infarction (MI) among older adults is limited. We evaluated sex differences in long-term cardiovascular outcomes after MI in older adults. Methods and Results All patients with MI ≥70 years admitted to 20 Finnish hospitals during a 10-year period and discharged alive were studied retrospectively using a combination of national registries (n=31 578, 51% men, mean age 79). The primary outcome was combined major adverse cardiovascular event within 10-year follow-up...
November 6, 2021: Journal of the American Heart Association
https://read.qxmd.com/read/34686874/combined-assessment-of-stress-cardiovascular-magnetic-resonance-and-angiography-to-predict-the-effect-of-revascularization-in-chronic-coronary-syndrome-patients
#23
JOURNAL ARTICLE
Jose Gavara, Nerea Perez, Victor Marcos-Garces, Jose V Monmeneu, Maria P Lopez-Lereu, Cesar Rios-Navarro, Elena De Dios, Clara Bonanad, Joaquim Cánoves, David Moratal, Patricia Palau, Gema Miñana, Julio Nunez, Francisco Javier Chorro, Vicente Bodi
AIMS: The role of revascularization in chronic coronary syndrome (CCS) and the value of ischaemia vs. anatomy to guide decision-making are in constant debate. We explored the potential of a combined assessment of ischaemic burden by vasodilator stress cardiovascular magnetic resonance (CMR) and presence of multivessel disease by angiography to predict the effect of revascularization on all-cause mortality in CCS. METHODS AND RESULTS: The study group comprised 1066 CCS patients submitted to vasodilator stress CMR pre-cardiac catheterization (mean age 66 ± 11 years, 69% male)...
October 23, 2021: European Journal of Preventive Cardiology
https://read.qxmd.com/read/34515451/usefulness-of-red-cell-distribution-width-to-predict-mortality-in-patients-undergoing-endovascular-repair-of-abdominal-aortic-aneurysms
#24
JOURNAL ARTICLE
Albert Castellà, Carles Diaz-Duran, Alina Velescu, Andrés Galarza, Manuel Miralles, Albert Clará
BACKGROUND: Red cell distribution width (RDW) reflecting impaired erythropoyesis, has been associated with poor prognosis and mortality in several conditions. The aim of this study was to determine the relationship between RDW and the 5-year survival after the endovascular repair of abdominal aortic aneurysms (EVAR) and its ability to improve the discriminative power of a survival predictive score. METHODS: Retrospective analysis of 284 patients undergoing EVAR at a single centre...
September 13, 2021: International Angiology: a Journal of the International Union of Angiology
https://read.qxmd.com/read/34473074/long-term-outcomes-of-veteran-patients-after-transcatheter-aortic-valve-replacement
#25
JOURNAL ARTICLE
Hani Jneid, Douglas Farmer, Riyad Y Kherallah, David Paniagua, Ali Denktas, Biswajit Kar, Lorraine Cornwell, Alvin Blaustein, Ourania Preventza, Ernesto Jimenez
BACKGROUND: Transcatheter aortic valve replacement (TAVR) has become a mainstay treatment for severe aortic stenosis and is increasingly used for veterans, producing excellent short-term outcomes. There is a paucity of long-term outcome data after TAVR in the veteran population. METHODS: We examined consecutive patients who underwent TAVR at a single Veterans Affairs medical center through 2019. Baseline characteristics, echocardiographic and angiographic variables, and clinical outcomes were abstracted...
September 2021: Journal of Invasive Cardiology
https://read.qxmd.com/read/34274921/-comparison-of-the-efficacy-of-trimetazidine-in-revascularized-and-non-revascularized-stable-angina-patients-based-on-the-onecaps-study
#26
RANDOMIZED CONTROLLED TRIAL
János Tomcsányi
UNLABELLED: Összefoglaló. Bevezetés: A közelmúltban publikált ATPCI-vizsgálat azt eredményezte, hogy közvetlenül a sikeres revaszkularizáció után alkalmazott trimetazidin biztonságos volt, de nem volt effektívebb a cardiovascularis halál, anginarekurrencia, cardialis hospitalizáció tekintetében, mint a random kettős vakmódszerrel alkalmazott placebo. Célkitűzés: Az általunk korábban végzett ONECAPS nyitott, obszervációs vizsgálat retrospektív analízisét kívántuk elvégezni annak eldöntésére, hogy az anginás betegeknél van-e különbség a trimetazidin prolong hatásosságában annak megfelelően, hogy korábban revaszkularizáció történt...
July 18, 2021: Orvosi Hetilap
https://read.qxmd.com/read/34120704/drug-adherence-and-long-term-outcomes-in-non-revascularized-patients-following-acute-myocardial-infarction
#27
JOURNAL ARTICLE
Razi Khan, Padma Kaul, Sunjidatul Islam, Anamaria Savu, Akshay Bagai, Sean van Diepen, Kevin R Bainey, Robert C Welsh, Shaun G Goodman
This study examined long-term outcomes and adherence to guideline-based medications in non-revascularized acute myocardial infarction (MI) patients undergoing and not undergoing angiography. We analyzed non-revascularized MI patients hospitalized in Alberta, Canada between 2010-2016 and categorized them according to whether they had undergone coronary angiography. Adherence to guideline-based medications was determined by the proportion of days covered (PDC) and subdivided into categories based on PDC: 0% (none), 1-40% (low), 40-79% (intermediate) and ≥ 80% (high)...
June 11, 2021: American Journal of Cardiology
https://read.qxmd.com/read/34049387/sex-difference-in-the-case-fatality-of-older-myocardial-infarction-patients
#28
JOURNAL ARTICLE
Ville Kytö, Maria Nuotio, Päivi Rautava
BACKGROUND: The female sex is associated with poorer outcomes after myocardial infarction (MI), although current evidence in older patients is limited and mixed. We sought to evaluate sex-based differences in outcome after MI in older patients. METHODS: Consecutive older (≥ 70 years) all-comer patients with out-of-hospital MI admitted to 20 hospitals in Finland between 2005-2014 were studied using national registries (n=40,654, mean age 80 years, 50% women). The outcome of interest was death within one year after MI...
May 28, 2021: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://read.qxmd.com/read/33831507/clinical-outcome-of-anomalous-coronary-artery-with-interarterial-course-in-adults-single-center-experience-combined-with-a-systematic-review
#29
JOURNAL ARTICLE
Maurits S H Blomjous, Ricardo P J Budde, Margreet W A Bekker, Robert M Kauling, Judith A A E Cuypers, Annemien E van den Bosch, Jolien W Roos-Hesselink, Alexander Hirsch
BACKGROUND: Anomalous coronary artery originating from the opposite sinus of Vasalva with interarterial course (ACAOS-IAC) is associated with sudden cardiac death (SCD) in young athletes. If identified in adulthood prognosis is usually more benign, resulting in a dilemma regarding revascularization. METHODS: This is a retrospective observational single-center study, including adults with ACAOS-IAC. Medical records between 2012 and 2019 were reviewed for management approach, mortality, cardiac death and coronary related adverse events...
July 15, 2021: International Journal of Cardiology
https://read.qxmd.com/read/33830043/impact-of-coronary-revascularization-on-outcomes-of-transcatheter-aortic-valve-implantation
#30
JOURNAL ARTICLE
Bilge Duran Karaduman, Hüseyin Ayhan, Telat Keleş, Engin Bozkurt
OBJECTIVE: Although the effect of coronary revascularization on clinical outcomes before and after transcatheter valve implantation (TAVI) is debatable, there is currently insufficient data to determine the most appropriate revascularization strategy. In this study, we present our single-center experience of percutaneous coronary intervention (PCI) and its effect on clinical outcomes and mortality in patients undergoing TAVI. METHODS: We performed a retrospective analysis of 526 consecutive patients at our center, and 127 patients with obstructive coronary artery disease were included in the study...
April 2021: Anatolian Journal of Cardiology
https://read.qxmd.com/read/33775749/revascularization-of-intermittent-claudicants-leads-to-more-chronic-limb-threatening-ischemia-and-higher-amputation-rates
#31
COMPARATIVE STUDY
Vashisht Madabhushi, Daniel Davenport, Stuart Jones, Sami Abul Khoudoud, Nathan Orr, David Minion, Eric Endean, Sam Tyagi
BACKGROUND: There is an increasing incidence of peripheral arterial disease (PAD). The most common symptomatic presentation of PAD is intermittent claudication (IC), reproducible leg pain with ambulation. The progression of symptoms beyond IC is rare, and a nonprocedural approach of smoking cessation, supervised exercise therapy, and best medical therapy can mitigate progression of IC. Despite the lack of limb- or life-threatening sequelae of IC, invasive treatment strategies of IC have experienced rapid growth...
September 2021: Journal of Vascular Surgery
https://read.qxmd.com/read/33721070/prognostic-value-of-inflammatory-biomarkers-in-5-year-survival-after-endovascular-repair-of-abdominal-aortic-aneurysms-in-a-predominantly-male-cohort-implications-for-practice
#32
JOURNAL ARTICLE
E Lecumberri, C Ruiz-Carmona, E Mateos, A Galarza, I Subirana, A Clara
BACKGROUND: Prognostic factors of long-term survival can guide selection of patients for endovascular repair of abdominal aortic aneurysms (EVAR). The aim of this study was to evaluate the relationship between the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), the lymphocyte-to-monocyte ratio (LMR) and the systemic immune-inflammation index (SIII) with survival after EVAR and to assess whether the addition of these biomarkers improved the prediction of survival after surgery...
March 15, 2021: World Journal of Surgery
https://read.qxmd.com/read/33602217/interdisciplinary-approach-in-emergency-revascularization-and-treatment-for-acute-mesenteric-ischemia
#33
JOURNAL ARTICLE
Alicja Zientara, Anja-Rebeka Domenghino, Igor Schwegler, Hans Bruijnen, Annelies Schnider, Markus Weber, Stefan Gutknecht, Nicolas Attigah
BACKGROUND: Mesenteric ischemia is associated with poor outcome and high overall mortality. The aim was to analyze an interdisciplinary treatment approach of vascular and visceral specialists focusing on the in-hospital outcome and follow-up in patients with acute and acute-on-chronic mesenteric ischemia. METHODS: From 2010 until 2017, 26 consecutive patients with acute or acute on chronic mesenteric ischemia were treated by an interdisciplinary team. Data were prospectively collected and retrospectively evaluated...
February 18, 2021: BMC Surgery
https://read.qxmd.com/read/33589758/intensive-blood-pressure-treatment-in-coronary-artery-disease-implications-from-the-systolic-blood-pressure-intervention-trial-sprint
#34
JOURNAL ARTICLE
Jiabin Zang, Jianwen Liang, Xiaodong Zhuang, Shaozhao Zhang, Xinxue Liao, Guifu Wu
To investigate the optimal blood pressure (BP) in patients with coronary artery disease (CAD), we conducted subgroup analysis using SPRINT data. The study sample included 1206 participants with CAD (of whom 692 underwent coronary revascularization) and 8127 participants without CAD. Participants were randomized into two groups (systolic BP target of 140 mm Hg vs. 120 mm Hg). The primary outcome was a composite of cardiovascular events. After a median follow-up of 3.9 years, the hazard ratios (HRs) for the primary outcome were 0...
February 15, 2021: Journal of Human Hypertension
https://read.qxmd.com/read/33508459/inadequate-adherence-to-imaging-surveillance-and-medical-management-in-patients-with-duplex-ultrasound-detected-carotid-artery-stenosis
#35
JOURNAL ARTICLE
Kris Boelitz, Caroline Jirka, Robert T Eberhardt, Jeffrey A Kalish, Jeffrey J Siracuse, Alik Farber, Douglas W Jones
OBJECTIVE: It is recommended that patients with ≥50% carotid artery stenosis undergo surveillance imaging and atherosclerotic risk reduction medical therapies, regardless of whether revascularization is performed. The objective of this study was to determine rates of adherence to these recommended measures and to identify risk factors for non-adherence. MATERIAL AND METHODS: A retrospective analysis was performed of all carotid DUS from 2016-2017 at a single institution...
January 25, 2021: Annals of Vascular Surgery
https://read.qxmd.com/read/33444068/prognostic-role-of-procalcitonin-in-st-elevation-myocardial-infarction-complicated-by-cardiogenic-shock
#36
JOURNAL ARTICLE
Yash Paul Sharma, Ganesh Kasinadhuni, Krishna Santosh, Nitin Kumar Parashar, Rakesh Sharma, Dinakar Bootla, Kewal Kanabar, Darshan Krishnappa
OBJECTIVE: Cardiogenic shock accounts for the majority of deaths amongst patients with ST-elevation myocardial infarction. Procalcitonin is elevated in acute myocardial infarction, especially when complicated by left heart failure, cardiogenic shock, resuscitated cardiac arrest, and bacterial infections. However, the prognostic utility of procalcitonin in ST-elevation myocardial infarction complicated by cardiogenic shock has not been systematically evaluated. METHODS: We performed a retrospective registry review of 125 patients with ST-elevation myocardial infarction and cardiogenic shock over 2 years at a tertiary referral hospital to examine the prognostic value of serum procalcitonin measurement at 24 hours after the onset of infarction for in-hospital mortality...
January 14, 2021: Asian Cardiovascular & Thoracic Annals
https://read.qxmd.com/read/33358184/sex-based-differences-in-revascularization-and-30-day-readmission-after-st-segment-elevation-myocardial-infarction-in-the-united-states
#37
JOURNAL ARTICLE
Diala A Steitieh, Daniel Y Lu, Ramsey K Kalil, Luke K Kim, Garima Sharma, Ilhwan Yeo, Dmitriy N Feldman, Jim W Cheung, Alicia Mecklai, Tracy K Paul, Rebecca R Ascunce, Nivee P Amin
BACKGROUND: Cardiovascular disease is the leading cause of death for women in the United States. Revascularization is considered the standard of care for treatment of ST-segment elevation myocardial infarction (STEMI) and is known to reduce readmission. However there is a paucity of data that examines the sex-dependent impact of revascularization on readmission. We aimed to investigate sex differences in revascularization rates, 30-day readmission rates, and primary cause of readmissions following STEMIs...
December 17, 2020: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://read.qxmd.com/read/33280321/pedal-acceleration-time-a-new-method-of-diagnosis-and-prognosis-in-peripheral-arteriopathy
#38
JOURNAL ARTICLE
Andreia Pinelo, Luís Loureiro, Sérgio Teixeira, João Castro, Carlos Veterano, Inês Antunes, Carlos Veiga, Daniel Mendes, Henrique Rocha, Rui Almeida
Introduction It is well recognized that the Ankle-Arm Index is unreliable in the diagnosis and prognosis of peripheral arteriopathy in patients with incompressible vessels, such as diabetics and chronic kidney patients. It is therefore important to define alternative strategies for assessing distal perfusion in this population. Arterial Doppler, a non-invasive technique available in any vascular laboratory, can be used to directly assess foot perfusion by interrogating the plantar arch and its nourishing arteries...
October 2020: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://read.qxmd.com/read/33200171/risk-of-arrhythmias-after-myocardial-infarction-in-patients-with-left-ventricular-systolic-dysfunction-according-to-mode-of-revascularization-a-cardiac-arrhythmias-and-risk-stratification-after-myocardial-infarction-carisma-substudy
#39
JOURNAL ARTICLE
Anna F Thomsen, Peter Karl Jacobsen, Lars Køber, Rikke Moerch Joergensen, Heikki V Huikuri, Poul Erik Bloch Thomsen, Uffe G Jacobsen, Christian Jøns
AIMS: The Cardiac Arrhythmias and RIsk Stratification after Myocardial infArction (CARISMA) study was an observational trial including 312 patients with acute myocardial infarction (MI) and left ventricular ejection fraction (LVEF) <40%. Primary percutaneous intervention (pPCI) was introduced 2 years after start of the enrolment, dividing the population into two groups: pre- and post-pPCI. This substudy sought to describe the influence of the mode of revascularization on long-term risk of new-onset atrial fibrillation (AF), bradyarrhythmia, and ventricular tachycardia and the subsequent risk of relevant major cardiovascular events (MACE)...
April 6, 2021: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/33159916/heart-failure-impairs-the-mechanotransduction-properties-of-human-cardiac-pericytes
#40
JOURNAL ARTICLE
Irene Giulia Rolle, Ilaria Crivellari, Andrea Zanello, Elisa Mazzega, Emiliano Dalla, Michela Bulfoni, Elisa Avolio, Alice Battistella, Marco Lazzarino, Alice Cellot, Celeste Cervellin, Sandro Sponga, Ugolino Livi, Nicoletta Finato, Gianfranco Sinagra, Aneta Aleksova, Daniela Cesselli, Antonio Paolo Beltrami
The prominent impact that coronary microcirculation disease (CMD) exerts on heart failure symptoms and prognosis, even in the presence of macrovascular atherosclerosis, has been recently acknowledged. Experimental delivery of pericytes in non-revascularized myocardial infarction improves cardiac function by stimulating angiogenesis and myocardial perfusion. Aim of this work is to verify if pericytes (Pc) residing in ischemic failing human hearts display altered mechano-transduction properties and to assess which alterations of the mechano-sensing machinery are associated with the observed impaired response to mechanical cues...
November 5, 2020: Journal of Molecular and Cellular Cardiology
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