keyword
https://read.qxmd.com/read/38513853/urban-canopy-airflow-dynamics-a-numerical-investigation-of-drag-forces-and-distribution-for-generic-neighborhoods-and-their-relationships-with-breathability
#21
JOURNAL ARTICLE
Mingjie Zhang, Xin Guo, Jiaying Li, Zhi Gao, Guohua Ji, Jianshun Zhang, Rriccardo Buccolieri
Thorough investigations of urban-canopy drag primarily stemming from pressure drag on building surfaces are necessary given the turbulent flows within complex urban areas. Moreover, a gap persists regarding the relationships between canopy drag and breathability. Therefore, this work delves into the canopy-layer airflow dynamics for generic urban neighborhoods by performing three-dimensional Reynolds-Averaged Navier-Stokes simulations. A total of 32 subcases are examined, encompassing uniform- and varying-height and diverse plan area densities (λp , categorized into groups of sparse: 0...
March 19, 2024: Science of the Total Environment
https://read.qxmd.com/read/38512290/improvement-of-clinical-findings-meibography-and-tear-film-parameters-in-pediatric-ocular-rosacea-patients-after-a-standard-treatment-protocol
#22
JOURNAL ARTICLE
Ali Ceylan, Irem Onal, Fahri Onur Aydin, Burak Mergen, Yusuf Yildirim
PURPOSE: The objective of this study was to illustrate the changes in ocular findings, meibography, and tear break-up time (TBUT) values in pediatric patients with ocular rosacea following a standardized treatment. METHODS: The study included consecutive patients diagnosed with ocular rosacea, referred to a tertiary hospital between 2021 and 2023. Each patient underwent biomicroscopic examinations, non-invasive TBUT assessments, corneal fluorescein staining (evaluated using the Oxford scoring system), and meibography...
March 21, 2024: Ocular Immunology and Inflammation
https://read.qxmd.com/read/38512091/-the-relationship-between-the-development-of-post-stroke-cognitive-impairment-and-changes-in-the-coagulation-component-of-hemostasis
#23
JOURNAL ARTICLE
I A Koltsov, I A Shchukin, E A Kovalenko, N S Karpova, Y E Shilov, O S Brusov
OBJECTIVE: To evaluate the relationship between the severity of post-stroke cognitive impairment (PSCI) and coagulation parameters assessed using the dynamic thrombophotometry. MATERIAL AND METHODS: Thirty-five patients with hemispheric ischemic stroke (IS) with moderate neurological deficit at admission were included. All patients underwent a comprehensive clinical and instrumental assessment according to the current guidelines. On days 10-14, the cognitive status of patients was assessed using the Montreal Cognitive Assessment (MoCA)...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://read.qxmd.com/read/38511370/-main-sources-of-soil-phosphorus-and-their-seasonal-changes-across-different-vegetation-restoration-stages-in-karst-region-of-southwest-china
#24
JOURNAL ARTICLE
Jia-Qi Liu, Yan Liang, Fan Xiao, Yi-Qing Han, Chuan-Xing Hu, Liu-Hong Wei, Min Duan
Investigating the main sources of soil phosphorus and their seasonal variations across different vegetation restoration stages in karst region of southwest China can deepen our understanding of soil phosphorus cycling during vegetation restoration, and provide scientific reference for the controlling of rocky desertification. Taking the typical karst ecosystems at different vegetation restoration stages in Guilin, Guangxi as the research objects, we conducted a one-year field experiment with three treatments: vegetation restoration for about 10 years (R10), 30 years (R30) and 50 years (R50)...
December 2023: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://read.qxmd.com/read/38510205/omics-data-analysis-reveals-the-system-level-constraint-on-cellular-amino-acid-composition
#25
JOURNAL ARTICLE
Yuanyuan Huang, Zhitao Mao, Yue Zhang, Jianxiao Zhao, Xiaodi Luan, Ke Wu, Lili Yun, Jing Yu, Zhenkun Shi, Xiaoping Liao, Hongwu Ma
Proteins play a pivotal role in coordinating the functions of organisms, essentially governing their traits, as the dynamic arrangement of diverse amino acids leads to a multitude of folded configurations within peptide chains. Despite dynamic changes in amino acid composition of an individual protein (referred to as AAP) and great variance in protein expression levels under different conditions, our study, utilizing transcriptomics data from four model organisms uncovers surprising stability in the overall amino acid composition of the total cellular proteins (referred to as AACell)...
June 2024: Synthetic and Systems Biotechnology
https://read.qxmd.com/read/38509983/identification-of-circadian-rhythm-related-gene-classification-patterns-and-immune-infiltration-analysis-in-heart-failure-based-on-machine-learning
#26
JOURNAL ARTICLE
Xuefu Wang, Jin Rao, Li Zhang, Xuwen Liu, Yufeng Zhang
BACKGROUND: Circadian rhythms play a key role in the failing heart, but the exact molecular mechanisms linking changes in the expression of circadian rhythm-related genes to heart failure (HF) remain unclear. METHODS: By intersecting differentially expressed genes (DEGs) between normal and HF samples in the Gene Expression Omnibus (GEO) database with circadian rhythm-related genes (CRGs), differentially expressed circadian rhythm-related genes (DE-CRGs) were obtained...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38509637/age-and-sex-differences-in-microvascular-responses-during-reactive-hyperaemia
#27
JOURNAL ARTICLE
Tom Citherlet, Antoine Raberin, Giorgio Manferdelli, Gustavo R Mota, Grégoire P Millet
Microvascular impairments are typical of several cardiovascular diseases. Near-infrared spectroscopy (NIRS) combined with a vascular occlusion test provides non-invasive insights into microvascular responses by monitoring skeletal muscle oxygenation changes during reactive hyperaemia. Despite increasing interest in the effects of sex and ageing on microvascular responses, evidence remains inconsistent. Therefore, the present study aimed to investigate the effects of sex and age on microvascular responsiveness...
March 20, 2024: Experimental Physiology
https://read.qxmd.com/read/38507101/multiparametric-magnetic-resonance-imaging-in-the-follow-up-of-non-muscle-invasive-bladder-tumors-after-intravesical-instillations-a-promising-tool
#28
JOURNAL ARTICLE
Clément Klein, Serge Brunelle, Mathias Illy, Valeria De Luca, Laure Doisy, François Lannes, Davidson Sypre, Nicolas Branger, Thomas Maubon, Stanislas Rybikowski, Mathilde Guérin, Gwenaëlle Gravis, Jochen Walz, Geraldine Pignot
PURPOSE: The standard follow-up for non-muscle-invasive bladder cancer is based on cystoscopy. Unfortunately, post-instillation inflammatory changes can make the interpretation of this exam difficult, with lower specificity. This study aimed to evaluate the interest of bladder MRI in the follow-up of patients following intravesical instillation. METHODS: Data from patients who underwent cystoscopy and bladder MRI in a post-intravesical instillation setting between February 2020 and March 2023 were retrospectively collected...
March 20, 2024: World Journal of Urology
https://read.qxmd.com/read/38506115/a-fully-spiking-coupled-model-of-a-deep-neural-network-and-a-recurrent-attractor-explains-dynamics-of-decision-making-in-an-object-recognition-task
#29
JOURNAL ARTICLE
Naser Sadeghnejad, Mehdi Ezoji, Reza Ebrahimpour, Mohamad Qodosi, Sajjad Zabbah
Objective. Object recognition and making a choice regarding the recognized object is pivotal for most animals. This process in the brain contains information representation and decision making steps which both take different amount of times for different objects. While dynamics of object recognition and decision making are usually ignored in object recognition models, here we proposed a fully spiking hierarchical model, explaining the process of object recognition from information representation to making decision...
March 20, 2024: Journal of Neural Engineering
https://read.qxmd.com/read/38504145/the-perceived-helpfulness-and-acceptability-of-a-bespoke-psychological-therapy-service-for-registered-nurses-experiencing-psychological-distress-a-qualitative-study
#30
JOURNAL ARTICLE
Dean Whybrow, Bethan Jones, Eunice Temeng, Carys Dale, Chris Bundy, Tessa Watts
AIM: To understand the perceived helpfulness and acceptability of a bespoke psychological therapy service for registered nurses. The service provided a free and confidential specialist mental health service to all healthcare professionals, including nurses and nursing students. DESIGN: An exploratory study using a descriptive qualitative approach. METHODS: A purposive sample of 20 registered nurses accessing a bespoke psychological therapy service in Wales participated in audio-recorded semi-structured interviews in January 2022...
March 19, 2024: Journal of Advanced Nursing
https://read.qxmd.com/read/38504062/-functional-rhinofiller-improvement-of-nasal-airflow-with-rhinofiller-a-retrospective-review
#31
JOURNAL ARTICLE
Francesco Calvani, Carola Grazia Corbetta, Carlo Macro, Emanuele Bartoletti
INTRODUCTION: Rhinofiller is an aesthetic medical technique that can significantly enhance facial aesthetics by employing hyaluronic acid infiltration. The aim of this study is to review the impact of aesthetic rhinofiller on nasal airflow. METHODS: This is a retrospective review of 63 consecutive patients. The evaluation of the change in nasal respiratory flow was performed subjectively using a Likert questionnaire and objectively using a rhinomanometer, which enabled active anterior rhinomanometry (AAR)...
March 19, 2024: Aesthetic Plastic Surgery
https://read.qxmd.com/read/38503228/impacts-of-mining-on-vegetation-phenology-and-sensitivity-assessment-of-spectral-vegetation-indices-to-mining-activities-in-arid-semi-arid-areas
#32
JOURNAL ARTICLE
Xiaofei Sun, Yingzhi Zhou, Songsong Jia, Huaiyong Shao, Meng Liu, Shiqi Tao, Xiaoai Dai
Measuring the impact of mining activities on vegetation phenology and assessing the sensitivity of vegetation indices (VIs) to it are crucial for understanding land degradation in mining areas and enhancing the carbon sink capacity following the ecological restoration of mines. To this end, we have developed a novel technical framework to quantify the impact of mining activities on vegetation, and applied it to the Bainaimiao copper mining area in Inner Mongolia. Phenological indices are extracted based on the VI time series data of Sentinel-2, and changes in phenological differences in various directions are used to quantify the impact of mining activities on vegetation...
March 18, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38502878/longitudinal-change-in-serum-neurofilament-light-chain-in-type-2-diabetes-and-early-diabetic-polyneuropathy-addition-denmark
#33
JOURNAL ARTICLE
Laura L Määttä, Signe T Andersen, Tina Parkner, Claus V B Hviid, Lasse Bjerg, Mustafa A Kural, Morten Charles, Esben Søndergaard, Jens Kuhle, Hatice Tankisi, Daniel R Witte, Troels S Jensen
OBJECTIVE: To investigate the longitudinal development of neurofilament light chain (NfL) levels in type 2 diabetes with and without diabetic polyneuropathy (+/-DPN) and to explore the predictive potential of NfL as a biomarker for DPN. RESEARCH DESIGN AND METHODS: We performed retrospective longitudinal case-control analysis of data from 178 participants of the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care-Denmark (ADDITION-Denmark) cohort of people with screen-detected type 2 diabetes...
March 19, 2024: Diabetes Care
https://read.qxmd.com/read/38502032/codesign-of-lynch-choices-tm-using-implementation-science-to-create-a-clinically-deliverable-patient-decision-support-website-to-transform-cancer-genetics-care-pathways
#34
JOURNAL ARTICLE
Kelly Kohut, Kate Morton, Lesley Turner, Rebecca Foster, Diana Eccles, Claire Foster
BACKGROUND: Resources including Patient Decision Aids (PtDA) are useful and valued by patients and clinicians to provide information and complement shared decision-making. Despite their promise, few PtDA exist for patients with genetic cancer susceptibility facing difficult decisions about risk management. We aimed to fill this gap, partnering with patients to codesign Lynch ChoicesTM , a PtDA website for families with Lynch Syndrome. In addition to a Patient Reference Panel, we purposively invited an international stakeholder panel including charities, public bodies, clinical and academic experts...
March 2024: Psycho-oncology
https://read.qxmd.com/read/38500485/a-potential-brain-functional-biomarker-distinguishing-patients-with-crohn-s-disease-with-different-disease-stages-a-resting-state-fmri-study
#35
JOURNAL ARTICLE
Mengting Huang, Guina Ma, Yan Zou, Hui Ma, Wenliang Fan, Xin Li, Liangru Zhu, Ping Han, Huan Wang, Heshui Shi
BACKGROUND: The previous studies have demonstrated that patients with Crohn's disease in remission (CD-R) have abnormal alterations in brain function. However, whether brain function changes in patients with Crohn's disease in activity (CD-A) and the relationship with CD-R are still unclear. In this study, we aimed to investigate whether the different levels of disease activity may differentially affect the brain function and to find the brain functional biomarker distinguishing patients with different disease stages by measuring the amplitude of low frequency fluctuations (ALFF)...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38500142/evaluation-of-the-offset-static-rope-evacuation-procedure-insights-from-a-safe-job-analysis
#36
JOURNAL ARTICLE
Eirik Bjorheim Abrahamsen, Håvard Mattingsdal, Håkon Bjorheim Abrahamsen
BACKGROUND: Recently, the Norwegian Helicopter Emergency Medical Service (HEMS) has developed a procedure for a special type of static rope rescue operation, referred to as the offset technique. In this technique, the helicopter is offset from the accident site, and the HEMS technical crew member uses an offset throw line to gain access to the scene. Today, there is little practical experience of such operations, and a need has been identified for more knowledge on the potential hazards encountered during this type of operation...
March 18, 2024: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://read.qxmd.com/read/38498863/dimensional-stability-of-additively-manufactured-diagnostic-maxillary-casts-fabricated-with-different-model-resins
#37
JOURNAL ARTICLE
Mustafa Borga Dönmez, Alena Bruna Wepfer, Mehmet Esad Güven, Gülce Çakmak, Martin Schimmel, Burak Yilmaz
PURPOSE: To evaluate the effect of model resin type and time interval on the dimensional stability of additively manufactured diagnostic casts. MATERIALS AND METHODS: Ten irreversible hydrocolloid impressions and 10 impressions from an intraoral scanner were made from a reference maxillary stone cast, which was also digitized with a laboratory scanner. Conventional impressions were poured in type III stone (SC), while digital impressions were used to additively manufacture casts with a nanographene-reinforced model resin (GP) or a model resin (DM)...
February 21, 2024: International Journal of Prosthodontics
https://read.qxmd.com/read/38492331/using-the-gamma-index-analysis-for-inter-fractional-comparison-of-in-beam-pet-images-for-head-and-neck-treatment-monitoring-in-proton-therapy-a-monte-carlo-simulation-study
#38
JOURNAL ARTICLE
Aafke Christine Kraan, Martina Moglioni, Giuseppe Battistoni, Davide Bersani, Andrea Berti, Pietro Carra, Piergiorgio Cerello, Mario Ciocca, Veronica Ferrero, Elisa Fiorina, Enrico Mazzoni, Matteo Morrocchi, Silvia Muraro, Ester Orlandi, Francesco Pennazio, Alessandra Retico, Valeria Rosso, Giancarlo Sportelli, Barbara Vischioni, Viviana Vitolo, Maria Giuseppina Bisogni
GOAL: In-beam Positron Emission Tomography (PET) is a technique for in-vivo non-invasive treatment monitoring for proton therapy. To detect anatomical changes in patients with PET, various analysis methods exist, but their clinical interpretation is problematic. The goal of this work is to investigate whether the gamma-index analysis, widely used for dose comparisons, is an appropriate tool for comparing in-beam PET distributions. Focusing on a head-and-neck patient, we investigate whether the gamma-index map and the passing rate are sensitive to progressive anatomical changes...
March 15, 2024: Physica Medica: PM
https://read.qxmd.com/read/38491507/mean-arterial-pressure-map-trial-study-protocol-for-a-multicentre-randomized-controlled-trial-to-compare-three-different-strategies-of-mean-arterial-pressure-management-during-cardiopulmonary-bypass
#39
JOURNAL ARTICLE
Alessandra Francica, Gina Mazzeo, Antonella Galeone, Daniele Linardi, Livio San Biagio, Giovanni Battista Luciani, Francesco Onorati
BACKGROUND: One of the main goals of cardiopulmonary bypass (CPB) is targeting an adequate mean arterial pressure (MAP) during heart surgery, in order to maintain appropriate perfusion pressures in all end-organs. As inheritance of early studies, a value of 50-60 mmHg has been historically accepted as the "gold standard" MAP. However, in the last decades, the CPB management has remarkably changed, thanks to the evolution of technology and the availability of new biomaterials. Therefore, as highlighted by the latest European Guidelines, the current management of CPB can no longer refer to those pioneering studies...
March 15, 2024: Trials
https://read.qxmd.com/read/38491405/test-retest-reliability-and-concurrent-validity-assessment-of-a-novel-high-frequency-sensor-device-for-anterior-tibial-translation-measurement-in-loaded-and-unloaded-condition-an-exploratory-cross-sectional-study
#40
JOURNAL ARTICLE
Valentin Deiss, Philippe Bähler, Pascal Kolly, Anton Schärer, Philippe Henle, Patric Eichelberger, Nathanael Lutz, Heiner Baur
BACKGROUND: Magnetic resonance imaging (MRI) and manual tests remain the standard for diagnosing anterior cruciate ligament (ACL) rupture. Furthermore, the passive knee displacement, also described as anterior tibial translation (ATT), is used in order to make decisions about surgery or to assess rehabilitation outcomes. Unfortunately, these manual tests are limited to passive situations, and their application to assess knee stability in loaded, weight-bearing positions are missing. Therefore, a new device with high-performance sensors and a new sensor setting was developed...
March 16, 2024: BMC Musculoskeletal Disorders
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