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https://www.readbyqxmd.com/read/29791340/design-of-a-delayed-xor-phase-detector-for-an-optical-phase-locked-loop-toward-high-speed-coherent-laser-communication
#1
Yang Liu, Shoufeng Tong, Shuai Chang, Yansong Song, Yan Dong, Xin Zhao, Zhe An, Fuwan Yu
Optical phase-locked loops are an effective detection method in high-speed and long-distance laser communication. Although this method can detect weak signal light and maintain a small bit error rate, it is difficult to perform because identifying the phase difference between the signal light and the local oscillator accurately has always been a technical challenge. Thus, a series of studies is conducted to address this issue. First, a delayed exclusive or gate (XOR) phase detector with multi-level loop compound control is proposed...
May 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29791321/innovative-multi-site-photoplethysmography-measurement-and-analysis-demonstrating-increased-arterial-stiffness-in-paediatric-heart-transplant-recipients
#2
Emma J Sharkey, Costanzo Di Maria, Annette Klinge, Alan Murray, Dingchang Zheng, John O'Sullivan, John Allen
OBJECTIVE: It has been documented that heart transplantation in children is often complicated by arterial hypertension and increased arterial stiffness. AIM: to use innovative multi-site photoplethysmography (MPPG) pulse measurement and analysis technology to assess arterial stiffness change in paediatric heart transplant recipients (HTR) in comparison with healthy control (HC) children. 
 
 Approach: 20 heart transplant (median age 13.5 years old) (8 male) recipients were compared to an overall age- and gender-matched group of 161 healthy controls (11...
May 23, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29790078/a-prm-approach-for-early-prediction-of-breast-cancer-response-to-chemotherapy-based-on-registered-mr-images
#3
Mohammed El Adoui, Stylianos Drisis, Mohammed Benjelloun
PURPOSE: This study aims to provide and optimize a performing algorithm for predicting the breast cancer response rate to the first round of chemotherapy using Magnetic Resonance Imaging (MRI). This provides an early recognition of breast tumor reaction to chemotherapy by using the Parametric Response Map (PRM) method. METHODS: PRM may predict the breast cancer response to chemotherapy by analyzing voxel-by-voxel temporal intra-tumor changes during one round of chemotherapy...
May 22, 2018: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29789646/age-related-differences-in-limb-fat-free-mass-and-fat-mass-in-healthy-chinese-adults
#4
Mei Bai, Rui Wang, Linhao Zhu, Guixin Li, Dongya Yuan, Li Wang, Tianbo Jin
Fat mass (FM) and fat-free mass (FFM) are important elements to evaluate nutritional status. The aims of this study were to establish reference values for FM and FFM of limbs, develop percentile distributions and assess age-related regional differences in body composition by multifrequency bioelectrical impedance analyzer (BIA) in healthy adults. A cross-sectional study was conducted on 3419 healthy subjects, 1595 men and 1824 women. Regional FM and FFM were measured by BIA. FM in men remained stable in both upper and lower limbs, with reference values (25-75th percentile) of 1-1...
May 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29787932/initial-data-on-adsorption-of-cs-and-sr-to-the-surfaces-of-microplastics-with-biofilm
#5
Mathew P Johansen, Emily Prentice, Tom Cresswell, Nick Howell
The adsorption of radiocesium and radiostrontium onto a range of natural materials has been well quantified, but not for the new media of environmental plastics, which may have enhanced adsorption due to surface-weathering and development of biofilms. Microplastic samples were deployed in freshwater, estuarine and marine conditions, then characterised using infrared spectroscopy to document changes to the plastic surface (vs interior). Synchrotron elemental mapping data revealed surfaces that were well-covered by accumulation of reactive water solutes and sulphur, but, in contrast, had highly discrete coverage of elements such as Fe and Ti, indicating adhered mineral/clay-associated agglomerates that may increase overall adsorption capacity...
May 19, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29786523/decision-support-beyond-total-savings-eligibility-and-potential-savings-for-individual-participants-from-changes-in-the-national-surveillance-strategy-for-bovine-viral-diarrhoea-bvd-in-ireland
#6
Jamie A Tratalos, Hans-Hermann Thulke, David A Graham, Maria Guelbenzu Gonzalo, Simon J More
Surveillance and management of livestock diseases is often evaluated with reference to expected sector-wide costs. In contrast, we calculate losses or savings for individual herd owners of a change in monitoring strategy during a national cattle disease eradication programme: bovine viral diarrhoea (BVD) in Ireland. The alternative strategy differs in how the disease is identified; by its sample- rather than census-based approach; and by its greater cost per test. We examined the costs faced by each breeding herd if testing were conducted using serology on a sample of young stock, in contrast to the current method of tissue-tag testing of all newborn calves...
July 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29781576/ultrasonography-for-the-assessment-of-skin-in-systemic-sclerosis-a-systematic-review
#7
Tânia Santiago, Mariana Santiago, Barbara Ruaro, Maria João Salvador, Maurizio Cutolo, J A P da Silva
OBJECTIVE: To identify and synthesise the best available evidence on the use of ultrasound to assess skin involvement in systemic sclerosis (SSc). METHODS: We conducted a systemic review of the literature on Pubmed MEDLINE and Embase, using the vocabulary terms: ('systemic sclerosis OR scleroderma') AND ('ultrasonography' OR 'Elasticity Imaging Techniques') AND ('skin' OR 'dermis'). Two independent reviewers selected articles, collected data from studies and carried out a manual search of the references from the studies included...
May 21, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29780044/-effect-of-misregistration-between-spect-and-ct-images-on-attenuation-correction-for-quantitative-bone-spect-imaging
#8
Mika Sakoshi, Norikazu Matsutomo, Tomoaki Yamamoto, Eisuke Sato
PURPOSE: The aim of this study was to evaluate the effect of misregistration between single-photon emission computed tomography (SPECT) and computed tomography (CT) images on bone SPECT. METHODS: We acquired SPECT and CT images of a body phantom filled with bone-equivalent solution and 99m Tc for evaluation of bone SPECT. SPECT images were reconstructed using attenuation correction maps obtained by shifting the attenuation coefficients from non-shifted values (reference)...
2018: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/29778549/linked-color-imaging-can-help-gastric-helicobacter-pylori-infection-diagnosis-during-endoscopy
#9
Tsung-Hsing Chen, Chen-Ming Hsu, Hao-Tsai Cheng, Yin-Yi Chu, Ming-Yao Su, Jun-Te Hsu, Ta-Sen Yeh, Chang-Fu Kuo, Cheng-Tang Chiu
BACKGROUND: Esophagogastroduodenoscopy (EGD) is a standard tool for detection of mucosal and submucosal lesions. However, identification of Helicobacter pylori (H. P) infection using EGD alone is limited in accuracy. Linked color imaging (LCI) is a novel tool to capture real-time image with sufficient contrast to observe mucosal microstructure. METHODS: This study aims to evaluate the applicability of LCI in the identification of H. pylori infection. Consecutive 122 patients scheduled for EGD were included...
May 16, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29777281/right-ventricular-systolic-function-parameters-in-hypoplastic-left-heart-syndrome
#10
S Javed Zaidi, Jamie Penk, Vivian W Cui, Supaluck Kanjanauthai, David A Roberson
Assessment of the systolic function of the right ventricle (RV) in patients with hypoplastic left heart syndrome (HLHS) is important. The asymmetric shape and heavy trabeculations make accurate assessment of RV systolic function challenging. Novel measures of RV function could be helpful in distinguishing reduced versus preserved function in HLHS and may also be worse in HLHS with preserved function compared to normal controls. These novel methods offer promise, but research and clinical applicability is hindered as no cut-off values for normal function have been established...
May 18, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29777006/in-vivo-characterization-and-quantification-of-neurofibrillary-tau-pet-radioligand-18-f-mk-6240-in-humans-from-alzheimer-s-disease-dementia-to-young-controls
#11
Tobey J Betthauser, Karly A Cody, Matthew D Zammit, Dhanabalan Murali, Alexander K Converse, Todd E Barnhart, Charles K Stone, Howard A Rowley, Sterling C Johnson, Bradley T Christian
Tau positron emission tomography (PET) imaging has potential for elucidating changes in the deposition of neuropathological tau aggregates that are occurring during the progression of Alzheimer's disease (AD). This work investigates in vivo kinetics, quantification strategies and imaging characteristics of a novel tau PET radioligand [18 F]MK-6240 in humans. Methods: Fifty-one individuals ranging from cognitively normal young controls to persons with dementia underwent T1-weighted magnetic resonance imaging (MRI), and [11 C]PiB and [18 F]MK-6240 PET imaging...
May 18, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29777003/impact-of-reference-target-region-selection-on-amyloid-pet-standard-uptake-value-ratios-in-the-phase-1b-prime-study-of-aducanumab
#12
Ping Chiao, Barry J Bedell, Brian Avants, Alex P Zijdenbos, Marilyn Grand'Maison, Paul O'Neill, John O'Gorman, Tianle Chen, Robert Koeppe
Standardized uptake value ratios (SUVRs) are commonly used to quantify tracer uptake in amyloid beta positron emission tomography (Aβ-PET). Here, we explore the impact of target and reference region of interest (ROI) selection on SUVR effect size using interventional data from the ongoing Phase Ib PRIME study (NCT01677572) of aducanumab (BIIB037) in patients with prodromal or mild Alzheimer's disease (AD). Methods: Florbetapir PET SUVR was calculated at baseline (screening) and Weeks 26 and 54 for patients randomized to placebo and each of four aducanumab doses (1, 3, 6, and 10 mg/kg), using whole cerebellum, cerebellar grey matter, cerebellar white matter, pons, and subcortical white matter as reference regions...
May 18, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29776333/transcriptomic-analysis-of-genes-in-soybean-in-response-to-peronospora-manshurica-infection
#13
Hang Dong, Shuangfeng Shi, Chong Zhang, Sihui Zhu, Mei Li, Jie Tan, Yue Yu, Liping Lin, Shirong Jia, Xujing Wang, Yuanhua Wu, Yuhui Liu
BACKGROUND: Soybean downy mildew (SDM), caused by Peronospora manshurica (Pm), is a major fungal disease in soybean. To date, little is known regarding the defense mechanism at molecular level and how soybean plants response to Pm infection. In this study, differential gene expression in SDM-resistant (HR) and SDM-susceptible (HS) genotype was analyzed by RNA-seq to identify differentially expressed genes (DEGs) following Pm infection. RESULTS: Of a total of 55,017 genes mapped to the soybean reference genome sequences, 2581 DEGs were identified...
May 18, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29774398/improved-detection-of-a-tumorous-involvement-of-the-mesorectal-fascia-and-locoregional-lymph-nodes-in-locally-advanced-rectal-cancer-using-dce-mri
#14
Marco Armbruster, Melvin D'Anastasi, Veronika Holzner, Martin E Kreis, Olaf Dietrich, Bernhard Brandlhuber, Anno Graser, Martina Brandlhuber
PURPOSE: The prediction of an infiltration of the mesorectal fascia (MRF) and malignant lymph nodes is essential for treatment planning and prognosis of patients with rectal cancer. The aim of this study was to assess the additional diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for the detection of a malignant involvement of the MRF and of mesorectal lymph nodes in patients with locally advanced rectal cancer. METHODS: In this prospective study, 22 patients with locally advanced rectal cancer were examined with 1...
May 17, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29773499/study-of-condylar-positional-changes-after-sagittal-split-osteotomy-for-mandibular-advancement-a-prospective-cohort-study
#15
Alberto Costas, Jacinto F Sanromán, Pilar Castro, Martín F Ferro, Annahys Lopez, Bogdan Stavaru
PURPOSE: To analyse the possible morphologic and positional changes of the mandibular condyles after orthognathic surgery. MATERIAL AND METHODS: A prospective cohort study was performed. Patients with mandibular retrognathism were surgically treated to advance the mandible. The study group included seventeen patients (34 condyles) treated with sagittal split osteotomies alone (4 patients) or in combination with maxillary osteotomies (13 patients). Only condyles located on the mandibular side that advance during surgery were studied, therefore only 25 condyles entered this prospective study...
April 22, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29773474/women-with-fear-of-childbirth-might-benefit-from-having-a-known-midwife-during-labour
#16
Ingegerd Hildingsson, Annika Karlström, Christine Rubertsson, Helen Haines
AIM: Having a known midwife at birth is valued by women across the world, however it is unusual for women with fear of childbirth to have access to this model of care. The aim of this study was to describe the prevalence and factors related to having access to a known midwife for women referred to counseling due to childbirth fear. We also wanted to explore if women's levels of childbirth fear changed over time. METHODS: A pilot study of 70 women referred to counseling due to fear of birth in 3 Swedish hospitals, and where the counseling midwife, when possible, also assisted during labour and birth...
May 14, 2018: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29773315/impact-of-dredged-material-disposal-on-soft-bottom-communities-in-a-recurrent-marine-dumping-area-near-to-guadalquivir-estuary-spain
#17
I Donázar-Aramendía, J E Sánchez-Moyano, I García-Asencio, J M Miró, C Megina, J C García-Gómez
This study assesses the effects of dredged material disposal in a recurrent marine dump near the Guadalquivir Estuary (south-western Spain). We compared the changes observed with two reference areas combining a classical ecological approach with new stable isotope techniques to analyse trophic structure. We detected permanent changes in the macrofaunal community structure as well as in the diversity and biotic indices applied, which showed higher values in the disposal area. The community in the marine dump had lost the natural temporal variations observed in the reference areas...
May 7, 2018: Marine Environmental Research
https://www.readbyqxmd.com/read/29772213/enhanced-liver-fibrosis-elf-score-reference-ranges-biological-variation-in-healthy-subjects-and-analytical-considerations
#18
Antonín Jabor, Zdenek Kubíček, Soňa Fraňková, Renáta Šenkeříková, Janka Franeková
BACKGROUND: The Enhanced Liver Fibrosis score has been recognized as a non-invasive test for liver fibrosis. However, reference intervals, biological variation and analytical performance have not been studied in detail so far. The aim was to acquire data that are essential for correct interpretation. METHODS: A total of 40 apparently healthy volunteers were evaluated for reference ranges of serum concentration of hyaluronic acid, aminoterminal propeptide of type III collagen, and tissue inhibitor of metalloproteases-1, and calculated ELF score...
May 14, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29768509/aging-related-trajectories-of-lung-function-in-the-general-population-the-doetinchem-cohort-study
#19
Sandra H van Oostrom, Peter M Engelfriet, W M Monique Verschuren, Maarten Schipper, Inge M Wouters, Marike Boezen, Henriëtte A Smit, Huib A M Kerstjens, H Susan J Picavet
The objective of this study was to explore trajectories of lung function decline with age in the general population, and to study the effect of sociodemographic and life style related risk factors, in particular smoking and BMI. For this purpose, we used data from the Doetinchem Cohort Study (DCS) of men and women, selected randomly from the general population and aged 20-59 years at inclusion in 1987-1991, and followed until the present. Participants in the DCS are assessed every five years. Spirometry has been performed as part of this assessment from 1994 onwards...
2018: PloS One
https://www.readbyqxmd.com/read/29767420/ocular-coherence-tomography-measured-changes-over-time-in-anterior-chamber-angle-and-diurnal-intraocular-pressure-after-laser-iridotomy-impact-study
#20
Ivailo Zhekov, Shahina Pardhan, Rupert Ra Bourne
IMPORTANCE: The change in the anatomical dimensions over time and the effect on diurnal intraocular pressure (DIOP) following laser peripheral iridotomy is poorly understood. BACKGROUND: To evaluate change over time in anterior chamber angle anatomy following laser peripheral iridotomy (LPI) in patients with primary angle closure compared to control eyes. Additionally, the effect of LPI on DIOP fluctuation was investigated. DESIGN: Longitudinal, prospective, double-randomized research study...
May 16, 2018: Clinical & Experimental Ophthalmology
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