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https://www.readbyqxmd.com/read/29656529/residue-transfer-and-risk-assessment-of-carbendazim-in-tea
#1
Li Zhou, Yaping Jiang, Qin Lin, Xuan Wang, Xinzhong Zhang, Jie Xu, Zongmao Chen
BACKGROUND: The carbendazim residue in tea was a public concern. The large gap in the maximum residue limits (MRLs) for carbendazim in tea made it difficult to conduct pesticide management. Therefore, a systemic evaluation of the residue and health risk of carbendazim from the tea garden to the brewed tea was investigated. RESULTS: The dissipation of carbendazim in tea shoots followed first-order rate kinetics, with a half-life (T1/2 ) of 2.6 days. In green tea manufacturing, the carbendazim decrease of 2...
April 15, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29656526/access-to-knowledge-and-the-global-abortion-policies-database
#2
Joanna N Erdman, Brooke Ronald Johnson
Research shows that women, healthcare providers, and even policy makers worldwide have limited or inaccurate knowledge of the abortion law and policies in their country. These knowledge gaps sometimes stem from the vague and broad terms of the law, which breed uncertainty and even conflict when unaccompanied by accessible regulation or guidelines. Inconsistency across national law and policy further impedes safe and evidence-based practice. This lack of transparency creates a crisis of accountability. Those seeking care cannot know their legal entitlements, service providers cannot practice with legal protection, and governments can escape legal responsibility for the adverse effects of their laws...
April 14, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29656353/adsorption-of-cu-ii-and-ni-ii-from-aqueous-solutions-by-taro-stalks-chemically-modified-with-diethylenetriamine
#3
Yao Lu, Deliang He, Huibin Lei, Jun Hu, Houqiang Huang, Huiying Ren
Taro stalks (TS) were modified by diethylenetriamine (DETA) to obtain the modified taro stalks adsorbents (recorded as MTSA). This kind of raw material is unprecedented and the method of modification is relatively simple. The physicochemical properties of MTSA were characterized by scanning electron microscope (SEM), FTIR, and zeta potential analyzer. The capacity of MTSA for adsorbing heavy metals under different influencing factors was tested by UV-visible spectrophotometer. The results indicated that the gaps between the microspheres of MTSA are more, which are conducive to adsorption...
April 14, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29656325/dosing-of-the-second-generation-cryoballoon-using-acute-time-to-pulmonary-vein-isolation-as-an-indicator-of-durable-ablation-in-a-canine-model
#4
Wilber Su, Nicolas Coulombe, Nicole Kirchhof, Erin Grassl, Dan Wittenberger
BACKGROUND: Rigid time-based dosing protocol(s) currently used in the clinic for cryoballoon ablation of atrial fibrillation may be inadequate to guide the circumferential and transmural cryothermal energy transfer across the pulmonary vein (PV) and may result in injury to collateral tissues or electrical gaps between the PV and left atrium (LA). OBJECTIVE: A physiologic endpoint (e.g., acute time-to-PV isolation a.k.a. time-to-effect; TTE) may be effective in the determination of a transmural lesion formation and may allow for individualized ablation dosing across each PV...
April 14, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29656306/oral-and-sublingual-immunotherapy-for-treatment-of-ige-mediated-food-allergy
#5
REVIEW
Amy M Scurlock
Development of active therapies for IgE-mediated food allergy is a critical action step toward alleviating the adverse medical, psychosocial, and economic burdens on affected patients and families. Significant progress has been observed specifically in the application of single-allergen oral and sublingual immunotherapy for treatment of IgE-mediated food allergy, with emphasis on milk, egg, and peanut as the primary allergens. Oral immunotherapy (OIT) has demonstrated efficacy in promoting immunomodulatory effects that lead to the clinical outcome of desensitization, defined as reduced reactivity while on active OIT, in the majority of treated individuals; however, achievement of sustained unresponsiveness following cessation of therapy has been observed in a smaller subset of treated subjects...
April 14, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29656190/effect-of-titanium-dioxide-nanoparticles-on-the-bioavailability-and-neurotoxicity-of-cypermethrin-in-zebrafish-larvae
#6
Meng Li, Qiong Wu, Qiangwei Wang, Dandan Xiang, Guonian Zhu
In aquatic environment, the presence of nanoparticles (NPs) has been reported to modify the bioavailability and toxicity of the organic toxicants. Nevertheless, the combined toxicity of NPs and the pesticides that were used world-widely still remains unclear. Cypermethrin (CYP), a synthetic pyrethroid insecticide, is commonly used for controlling agricultural and indoor pests. Therefore, the effects of titanium dioxide NPs (nTiO2 ) on CYP bioconcentration and its effects on the neuronal development in zebrafish were investigated in our study...
March 31, 2018: Aquatic Toxicology
https://www.readbyqxmd.com/read/29656144/short-and-long-term-management-of-cases-of-venom-induced-anaphylaxis-via-is-suboptimal
#7
Ashley Tritt, Sofianne Gabrielli, Sarah Zahabi, Ann Clarke, Jocelyn Moisan, Harley Eisman, Judy Morris, Lea Restivo, Greg Shand, Moshe Ben-Shoshan
BACKGROUND: Venom induced anaphylaxis (VIA) accounts for severe reactions. However, little is known about the short and long-term management of VIA cases. OBJECTIVE: To assess the short and long-term management of VIA. METHODS: Using a national anaphylaxis registry (C-CARE), we identified VIA cases presenting to EDs in Montreal and to emergency medical services(EMS) in Western Quebec over a four-year period. Data were collected on clinical characteristics, triggers, and management...
April 12, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29656030/post-stroke-depression-the-sequelae-of-cerebral-stroke
#8
REVIEW
Jyotirekha Das, G K Rajanikant
Post-stroke depression (PSD) is the most common mental health issue, afflicting around 33% of stroke survivors. PSD has a negative impact on the rehabilitation, recuperation of motor and cognitive deficits following stroke and significantly increases the chances of relapsing neurovascular events. It has been demonstrated that biological and psychological factors have a significant role in PSD. Numerous endeavors have been made to discover the risk factors and predictors of PSD. Screening and diagnosis also have gained attention; however, a suitable tool is yet to be developed...
April 12, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29656019/proteomic-identification-of-virulence-related-factors-in-young-and-aging-c-elegans-infected-with-pseudomonas-aeruginosa
#9
Christina D King, Daljeet Singh, Kyle Holden, Annie B Govan, Scott A Keith, Arjumand Ghazi, Renã A S Robinson
The molecular mechanisms that distinguish immunosenescence from general age-related decline are poorly understood. We addressed this by exposing Day 1 and Day 5 adults of Caenorhabditis elegans to Pseudomonas aeruginosa strain PA01, an opportunistic pathogen. Day 5 adult C. elegans exhibited greater vulnerability to infection as compared to Day 1 C. elegans. Using TMT6 -plex isobaric labeling and reductive dimethylation, we identified 55 proteins whose levels were altered following infection of Day 1 and Day 5 adults...
April 12, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29655955/employment-and-paid-work-among-participants-in-a-randomized-controlled-trial-comparing-diacetylmorphine-and-hydromorphone
#10
Mohammadali Nikoo, Marc Vogel, Fiona Choi, Michael J Song, Jensen Burghardt, Zafar Zafari, Katarina Tabi, Anastasia Frank, Skye Barbic, Christian Schütz, Kerry Jang, Michael Krausz
BACKGROUND: Employment is one of the less studied but a significant outcome of medication-assisted treatment. Thus, we aimed to explore employment outcomes of medication-assisted treatment with hydromorphone (HDM) or diacetylmorphine (DAM). The secondary aim was to estimate characteristics of this population as well as treatment-related factors associated with these outcomes. METHODS: This was a secondary analysis of a randomized, double blind controlled trial. A total of 102 and 100 participants were randomized to receive injectable DAM or HDM for 6 months respectively...
April 12, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29655933/-document-management-systems-to-support-quality-management-systems-at-university-hospitals-an-interview-based-study
#11
Martin Holderried, Ann-Catrin Bökel, Elke Ochsmann
In order to save and control the processes and quality of medical services, a suitable steering system of all relevant documents is essential from the point of view of clinical quality management. Systems supporting an automated steering system of documents are called document management systems (DMS), and they also enter the healthcare sector. The use of DMS in the German healthcare sector has hardly been investigated so far. To close this knowledge gap, interviews were carried out with German university hospitals over a six-month period and subjected to a qualitative content analysis according to Mayring...
April 12, 2018: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/29655919/endocannabinoid-system-in-systemic-lupus-erythematosus-first-evidence-for-a-deranged-2-arachidonoylglycerol-metabolism
#12
Luca Navarini, Tiziana Bisogno, Pamela Mozetic, Fabiana Piscitelli, Domenico Paolo Emanuele Margiotta, Fabio Basta, Antonella Afeltra, Mauro Maccarrone
The endocannabinoid (eCB) system plays a key role in many physiological and pathological conditions and its dysregulation has been described in several rheumatological and autoimmune diseases. Yet, its possible alteration in systemic lupus erythematosus (SLE) has never been investigated. Here, we aimed filling this gap in plasma and peripheral blood mononuclear cells (PBMCs) of patients with SLE and age- and sex- matched healthy subjects (HS). Liquid chromatography-mass spectrometry quantitation of eCB levels highlighted that plasma levels of 2-arachidonoylglycerol (2-AG) were significantly increased in SLE patients compared to HS (p = 0...
April 12, 2018: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/29655747/comparative-performances-of-lactoferrin-loaded-liposomes-under-in-vitro-adult-and-infant-digestion-models
#13
Weilin Liu, Junmeng Lu, Aiqian Ye, Qingqing Xu, Mengmeng Tian, Youyu Kong, Fuqiang Wei, Jianzhong Han
There remain gaps in our understanding of the fate of liposomes in the infant gastrointestinal tract, especially regarding essential proteins such as lactoferrin. Models in vitro that mirrored digestion in the stomach and intestine of infants and adults were used to explore the behaviour of lactoferrin-loaded liposomes. The liposomes behaved differently in these environments, with less hydrolysis of encapsulated lactoferrin under infant model conditions. Compared to the adult model (1000 ± 66 μM mL-1 ), fewer free fatty acids were released (500 ± 43 μM mL-1 ) from liposomal bilayers and there was less alteration in functional groups of phospholipids membranes, based on pH and FTIR after infant model digestion...
August 30, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29655553/transitional-care-post-tavi-a-pilot-initiative-focused-on-bridging-gaps-and-improving-outcomes
#14
Sandra Wong, Lorraine Montoya, Bonnie Quinlan
Interventions focused on ensuring safe transitions for patients from hospital to home can assist in providing continuity of care, preventing readmissions, and reducing duplication of services. Patients undergoing a Transcatheter Aortic Valve Implantation (TAVI) procedure are often frail, elderly, and have multiple co-morbidities. A pilot initiative evaluating transitional care strategies through telephone follow up was implemented in a tertiary centre with the aim to identify gaps and intervene, preventing re-admission and improving patient outcomes...
April 11, 2018: Geriatric Nursing
https://www.readbyqxmd.com/read/29655522/antibiotics-as-instigators-of-microbial-dysbiosis-implications-for-asthma-and-allergy
#15
REVIEW
Tomasz P Wypych, Benjamin J Marsland
The human body and its resident microbiota form a complex ecosystem, shaped by both inherited and environmental factors. The use of antibiotics represents an extreme example of environmental pressure and can broadly disrupt the microbial landscape. The benefits that antibiotics have brought to modern medicine are unquestionable; however, their overuse comes with consequences, including the potential for secondary infections by opportunistic pathogens and the spread of antibiotic resistance. Here, we discuss the implications of microbial dysbiosis driven by antibiotics, with a focus on potential links with allergy and asthma...
March 14, 2018: Trends in Immunology
https://www.readbyqxmd.com/read/29655357/soft-phonon-modes-driven-huge-difference-on-lattice-thermal-conductivity-between-topological-semimetal-wc-and-wn
#16
San-Dong Guo, Peng Chen
Topological semimetals are currently attracting increasing interest due to their potential applications in topological qubits and low-power electronics, which are closely related to their thermal transport properties. Recently, the triply degenerate nodal points near the Fermi level of WC are observed by using angle-resolved photoemission spectroscopy. In this work, by solving the Boltzmann transport equation based on first-principles calculations, we systematically investigate the phonon transport properties of topological semimetals WC and WN...
April 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29653168/purification-partial-characterization-and-inducing-tumor-cell-apoptosis-activity-of-a-polysaccharide-from-ganoderma-applanatum
#17
Dong Zhen, Ling Su, Yue Miao, Fei Zhao, Guihong Ren, Shad Mahfuz, Hui Song
In this study, a homogeneous polysaccharide (designated as GAP-3S) with an average molecular weight of 6.82×105 Da was purified from Ganoderma applanatum. GAP-3S was composed of glucose, galactose, fucose and xylose in the molar ratio of 7.1:2.6:1.1:1. It could significantly inhibit the proliferation of MCF-7 cells in a dose- and time-dependent manner. Flow cytometry analysis indicated that GAP-3S could also induce cell apoptosis. Treatment of MCF-7 cells with GAP-3S lead to the collapse of mitochondrial membrane potential and the accumulation of ROS, up-regulated expression of Bax, cleavage of PARP, p-p38 and p-JNK, and the down-regulated expression of Bcl-2, PARP and p-ERK...
April 10, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29653050/dissolution-of-complex-metal-oxides-from-first-principles-and-thermodynamics-cation-removal-from-the-001-surface-of-li-ni-1-3-mn-1-3-co-1-3-o-2
#18
Joseph Bennett, Diamond Jones, Xu Huang, Robert J Hamers, Sara E Mason
The rapid increase in use of Li-ion batteries in portable electronics has created a pressing need to understand the environmental impact and long-term fate of electonic waste (e-waste) products such as heavy and/or reactive metals. The type of e-waste that we focus on here are the complex metal oxide nanomaterials that compose Li-ion battery cathodes. While in operation the complex metal oxides are in a hermetically sealed container. However, at the end of life, improper disposal can cause structural transformations such as dissolution and metal leaching, resulting in a significant exposure risk to the surrounding environment...
April 13, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29652954/-time-to-change-the-graduate-postgraduate-liaison-in-chilean-medical-education-reflections-about-a-double-certification-as-physician-and-doctor-in-medical-sciences
#19
Miguel Concha M
In the last 150 years, scientific research has produced extraordinary discoveries in Medicine and there is no doubt that research will continue contributing substantially in the future but there is no the same conviction regarding how to provision such capacities in medical graduates. In Chile, the Faculties of Medicine created several doctorate programs in Medical Sciences (Ph.D.) to strengthen medical research. However, the low number of physicians who apply to these programs is a caveat. These programs provide the advanced third-cycle competencies expected by students aspiring for an excellence research certification and their incorporation into academia...
December 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29652936/does-scale-matter-a-systematic-review-of-incorporating-biological-realism-when-predicting-changes-in-species-distributions
#20
Sydne Record, Angela Strecker, Mao-Ning Tuanmu, Lydia Beaudrot, Phoebe Zarnetske, Jonathan Belmaker, Beth Gerstner
BACKGROUND: There is ample evidence that biotic factors, such as biotic interactions and dispersal capacity, can affect species distributions and influence species' responses to climate change. However, little is known about how these factors affect predictions from species distribution models (SDMs) with respect to spatial grain and extent of the models. OBJECTIVES: Understanding how spatial scale influences the effects of biological processes in SDMs is important because SDMs are one of the primary tools used by conservation biologists to assess biodiversity impacts of climate change...
2018: PloS One
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