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https://www.readbyqxmd.com/read/28651422/-meta-analysis-on-the-diagnostic-value-of-laser-doppler-imaging-for-burn-depth
#1
Y Huang, L Qiu, A L Mei, J X Li
Objective: To evaluate the value of laser Doppler imaging (LDI) in diagnosing deep or superficial partial-thickness burn wound with meta-analysis. Methods: Databases including PubMed, Cochrane Library were searched using key words " burn, burns, burn depth, laser Doppler imaging, laser Doppler perfusion imaging, LDI, LDPI" , and Chinese Journals Full-text Database, Wanfang Database, VIP Database were searched using Chinese key words ",,,," to obtain the published trials of LDI in diagnosing deep or superficial partial-thickness burn wound from the establishment of each database to October 2015...
May 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28651421/-effects-of-change-in-the-activity-of-vacuolar-adenosine-triphosphatase-of-myocardial-lysosome-on-myocardial-damage-in-rats-after-severe-burn-and-its-mechanism
#2
X P Yan, D X Zhang, T T Yan, Q Zhang, J Z Jia, Y S Huang
Objective: To explore the effects of change of activity of vacuolar adenosine triphosphatase (V-ATPase) of myocardial lysosome on myocardial damage in rats after severe burn and its mechanism. Methods: The myocardial lysosomes were extracted from the hearts of 12 SD rats with ultra-high speed gradient density centrifugation, then Western blotting and transmission electron microscope observation were conducted for identification. One hundred and twenty rats were divided into pure burn group, ATP group, normal control group, and bafilomycin group according to the random number table, with 30 rats in each group...
May 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28651420/-effects-of-hypoxia-inducible-factor-1%C3%AE-on-p311-and-its-influence-on-the-migration-of-murine-epidermal-stem-cells
#3
Z D Xu, H S Li, S Wang, W F He, J Wu, G X Luo
Objective: To explore the effects of hypoxia inducible factor-1α (HIF-1α) on P311 and its influence on the migration of murine epidermal stem cells (ESCs) under hypoxia in vitro. Methods: Two kinds of murine ESCs were isolated and obtained from 15 neonatal wild-type C57BL/6J mice and 5 congeneric source P311 gene knock-out mice, respectively. The first passage of cells were used in the following experiments after morphologic observation and detection of expression of cell surface markers CD71 and CD49f with flow cytometer...
May 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28651416/-clinical-effects-of-joint-active-system-on-the-treatment-of-joint-dysfunction-after-deep-burn
#4
T F Ru, F F Li, P Chen, H Luo, L Yuan, F Lei, Y L Tang, W G Xie
Objective: To observe the clinical effects of the Joint Active System on the treatment of joint dysfunction after deep burn. Methods: Twenty-two patients with joint dysfunction after deep burn were hospitalized in Institute of Burns of Tongren Hospital of Wuhan University & Wuhan Third Hospital from January 2015 to October 2016, involving 18 elbow joints with flexion disorder, 10 wrist joints with dorsal extension disorder, and 12 ankle joints with dorsal extension disorder. They were treated with the elbow joint activity training device, the wrist joint activity training device, and the ankle joint activity training device of the Joint Active System, respectively...
May 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28651254/a-preliminary-study-of-a-spanish-graphic-novella-targeting-hearing-loss-prevention
#5
Mark Guiberson, Emily Wakefield
Purpose: This preliminary study developed a digital graphic novella targeting hearing protection beliefs of Spanish-speaking agricultural workers. Researchers used pretest-posttest interview surveys to establish if the novella had an immediate influence on the participants' beliefs about noise-induced hearing loss and usage of hearing protection devices. Method: Researchers developed a digital graphic novella directed to increase knowledge about noise-induced hearing loss and increase the proper use of hearing protection devices...
June 23, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/28651242/chalcogen-substitution-effect-of-oxygen-by-sulfur-exchange-on-structural-and-spectroscopic-properties-of-flavonols
#6
Cécilia Falantin, Aurélien Moncomble, Annaïg Le Person, Jean-Paul Cornard
Quantum chemical calculations using density functional theory have revealed that the substitution of the ketone group by a thioketone one doesn't significantly change the structure of 3-hydroxyflavone. Notably, the strong intramolecular hydrogen bond involving the hydroxyl function is preserved if the O atom is substituted by an S atom, but also by Se or Te atoms. However, fundamental modifications are observed in both absorption and emission electronic spectra upon substitution, particularly the non-fluorescent behavior of the flavothione...
June 17, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28651215/anticipatory-postural-adjustment-patterns-during-gait-initiation-across-the-adult-lifespan
#7
Chiahao Lu, Sommer L Amundsen Huffmaster, Jack C Harvey, Colum D MacKinnon
Gait initiation involves a complex sequence of anticipatory postural adjustments (APAs) during the transition from steady state standing to forward locomotion. APAs have four core components that function to accelerate the center of mass forwards and towards the initial single-support stance limb. These components include loading of the initial step leg, unloading of the initial stance leg, and excursion of the center of pressure in the posterior and lateral (towards the stepping leg) directions. This study examined the incidence, magnitude, and timing of these components and how they change across the lifespan (ages 20-79)...
June 16, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28651159/health-related-quality-of-life-results-from-the-phase-iii-checkmate-067-study
#8
Dirk Schadendorf, James Larkin, Jedd Wolchok, F Stephen Hodi, Vanna Chiarion-Sileni, Rene Gonzalez, Piotr Rutkowski, Jean-Jacques Grob, C Lance Cowey, Christopher Lao, John Wagstaff, Margaret K Callahan, Michael A Postow, Michael Smylie, Pier Francesco Ferrucci, Reinhard Dummer, Andrew Hill, Fiona Taylor, Javier Sabater, Dana Walker, Srividya Kotapati, Amy Abernethy, Georgina V Long
BACKGROUND: Nivolumab, a monoclonal antibody of immune checkpoint programmed death 1 on T cells (PD-1), combined with ipilimumab, an immune checkpoint cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibitor, as combination therapy on the one hand and nivolumab as monotherapy on the other, have both demonstrated improved efficacy compared with ipilimumab alone in the CheckMate 067 study. However, the combination resulted in a higher frequency of grade 3/4 adverse events (AEs), which could result in diminished health-related quality of life (HRQoL)...
June 22, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28651092/role-of-proteoglycans-on-the-biochemical-and-biomechanical-properties-of-dentin-organic-matrix
#9
Cristina de Mattos Pimenta Vidal, Ariene Arcas Leme-Kraus, Momina Rahman, Ana Paula Farina, Ana K Bedran-Russo
OBJECTIVE: Proteoglycans (PGs) are multifunctional biomacromolecules of the extracellular matrix of collagen-based tissues. In teeth, besides a pivotal regulatory role on dentin biomineralization, PGs provide mechanical support to the mineralized tissue and compressive strength to the biosystem. This study assessed enzymatic protocols for selective PGs removal from demineralized dentin to determine the roles of these biomacromolecules in the bulk mechanical properties and biostability of type I collagen...
June 16, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28651047/prioritization-of-contaminants-of-emerging-concern-in-wastewater-treatment-plant-discharges-using-chemical-gene-interactions-in-caged-fish
#10
Edward J Perkins, Tanwir Habib, Barbara L Escalon, Jenna E Cavallin, Linnea Thomas, Matthew Weberg, Megan N Hughes, Kathleen M Jensen, Michael D Kahl, Daniel L Villeneuve, Gerald T Ankley, Natalia Garcia-Reyero
We examined whether contaminants present in surface waters could be prioritized for further assessment by linking the presence of specific chemicals to gene expression changes in exposed fish. Fathead minnows were deployed in cages for 2, 4, or 8 days at three locations near two different wastewater treatment plant discharge sites in the Saint Louis Bay, Duluth, MN and one upstream reference site. The biological impact of 51 chemicals detected in the surface water of 133 targeted chemicals was determined using biochemical endpoints, exposure activity ratios for biological and estrogenic responses, known chemical:gene interactions from biological pathways and knowledge bases, and analysis of the co-variance of ovary gene expression with surface water chemistry...
June 26, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28651045/photoinduced-charge-transfer-versus-fragmentation-pathways-in-lanthanum-cyclopentadienyl-complexes
#11
Yulun Han, Qingguo Meng, Bakhtiyor Rasulev, P Stanley May, Mary T Berry, Dmitri S Kilin
This study compares two competing pathways of photoexcitations in gas-phase metal-organic complexes: first, a sequence of phonon-assisted electronic transitions leading to dissipation of the energy of photoexcitations and second, a sequence of light-driven electronic transitions leading to photolysis. Phonon-assisted charge carrier dynamics is investigated by combination of the density matrix formalism and on-the-fly nonadiabatic couplings. Light-driven fragmentation is modeled by a time-dependent excited-state molecular dynamics (TDESMD) algorithm based on Rabi theory and principles similar to the trajectory surface hopping approximation...
June 26, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28651043/visualizing-the-contributions-of-virtual-states-to-two-photon-absorption-cross-sections-by-natural-transition-orbitals-of-response-transition-density-matrices
#12
Kaushik D Nanda, Anna I Krylov
Observables such as two-photon absorption cross-sections cannot be computed from the wave functions of the initial and final states alone because of their nonlinear nature. Rather, they depend on the entire manifold of the excited states, which follows from the familiar sum-over-states expressions of second- and higher-order properties. Consequently, the interpretation of the computed nonlinear optical properties in terms of molecular orbitals is not straightforward and usually relies on approximate few-states models...
June 26, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28651020/the-nervous-system-of-the-adult-ascidian-ciona-intestinalis-type-a-ciona-robusta-insights-from-transgenic-animal-models
#13
Tomohiro Osugi, Yasunori Sasakura, Honoo Satake
The nervous system of ascidians is an excellent model system to provide insights into the evolutionary process of the chordate nervous system due to their phylogenetic positions as the sister group of vertebrates. However, the entire nervous system of adult ascidians has yet to be functionally and anatomically investigated. In this study, we have revealed the whole dorsal and siphon nervous system of the transgenic adult ascidian of Ciona intestinalis Type A (Ciona robusta) in which a Kaede reporter gene is expressed in a pan-neuronal fashion...
2017: PloS One
https://www.readbyqxmd.com/read/28650960/phosphatidylserine-externalization-necroptotic-bodies-release-and-phagocytosis-during-necroptosis
#14
Sefi Zargarian, Inbar Shlomovitz, Ziv Erlich, Aria Hourizadeh, Yifat Ofir-Birin, Ben A Croker, Neta Regev-Rudzki, Liat Edry-Botzer, Motti Gerlic
Necroptosis is a regulated, nonapoptotic form of cell death initiated by receptor-interacting protein kinase-3 (RIPK3) and mixed lineage kinase domain-like (MLKL) proteins. It is considered to be a form of regulated necrosis, and, by lacking the "find me" and "eat me" signals that are a feature of apoptosis, necroptosis is considered to be inflammatory. One such "eat me" signal observed during apoptosis is the exposure of phosphatidylserine (PS) on the outer plasma membrane. Here, we demonstrate that necroptotic cells also expose PS after phosphorylated mixed lineage kinase-like (pMLKL) translocation to the membrane...
June 26, 2017: PLoS Biology
https://www.readbyqxmd.com/read/28650951/development-and-progression-of-a-lamellar-macular-hole-with-lamellar-hole-associated-epiretinal-proliferation
#15
Denise Compera, Matteo G Cereda, Ricarda G Schumann, Ferdinando Bottoni
PURPOSE: To describe evolution and progression of a lamellar macular hole (LMH) with "lamellar hole-associated epiretinal proliferation (LHEP)" using spectral-domain optical coherence tomography and fundus autofluorescence. METHODS: Observational case report. RESULTS: We report on a 63-year-old male patient demonstrating a complete history of LMH development with LHEP occurring during a follow-up period of 8 years. Presenting with a normal foveal contour and attached posterior vitreous at first visit, an LMH developed shortly after incomplete posterior vitreous detachment with vitreopapillary adhesion...
June 23, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28650799/learning-the-personalized-intransitive-preferences-of-images
#16
Jun Chen, Chaokun Wang, Jianmin Wang, Xiang Ying, Xuecheng Wang
Most of the previous studies on the user preferences assume that there is a personal transitive preference ranking of the consumable media like images. For example, the transitivity of preferences is one of the most important assumptions in the recommender system research. However, the intransitive relations have also been widely observed, such as the win/loss relations in online video games, in sport matches, and even in rock-paper-scissors games. It is also found that different subjects demonstrate the personalized intransitive preferences in the pairwise comparisons between the applicants for college admission...
September 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28650782/effect-of-probiotic-yogurt-and-xylitol-containing-chewing-gums-on-salivary-s-mutans-count
#17
Elnaz Ghasemi, Romina Mazaheri, Arezoo Tahmourespour
BACKGROUND AND AIMS: In addition to improving gastrointestinal health and intestinal microflora, probiotic bacteria have been recently suggested to decrease cariogenic agents in the oral cavity. The aim of this study was to investigate the effects of probiotic yogurt and xylitol-containing chewing gums on reducing salivary Streptococcus mutans levels. STUDY DESIGN: This randomized clinical trial recruited 50 female students with over 10(5) colony forming units S...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28650608/internally-externally-bubble-propelled-photocatalytic-tubular-nanomotors-for-efficient-water-cleaning
#18
Sheng Wang, Zhenzhen Jiang, Shenshen Ouyang, Zhipeng Dai, Tao Wang
We describe a highly effective bubble-propelled nanomotor for the photocatalytic decomposition of organic pollutants in water. Two different tubular TiO2 nanomotor systems are presented: one with Pt nanoparticles decorated on the inner surface and the other with Pt nanoparticles decorated on the outer surface. This is the first time that we have observed the autonomous movement of a tubular nanomotor without the aid of any surfactant, as well as a tubular nanomotor externally decorated with Pt propelled by oxygen bubbles...
June 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28650604/serum-adiponectin-levels-in-adolescents-and-young-adults-with-growth-hormone-deficiency
#19
(no author information available yet)
INTRODUCTION: Adiponectin (APN) is adipose tissue-derived hormone influencing energy metabolism. Growth hormone deficiency (GHD) may contribute to the development of disturbances in the hormonal function of adipose tissue (AT), and many disorders observed in untreated patients with GHD coincides with these contributed to low serum APN levels. OBJECTIVES: The assessment of serum adiponectin levels in adolescents and young adults with severe or partial GHD and analysis of relationships between serum APN and GH/IGF-1 axis function impairment as well as cardiometabolic risk factors...
May 26, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28650409/platelet-rich-fibrin-accelerates-skin-wound-healing-in-diabetic-mice
#20
Yinjia Ding, Lei Cui, Qiming Zhao, Weiqiang Zhang, Huafeng Sun, Lijun Zheng
Diabetic foot ulcers (DFUs) are associated with an increased risk of secondary infection and amputation. Platelet-rich fibrin (PRF), a platelet and leukocyte concentrate containing several cytokines and growth factors, is known to promote wound healing. However, the effect of PRF on diabetic wound healing has not been adequately investigated. The aim of the study was to investigate the effect of PRF on skin wound healing in a diabetic mouse model. Platelet-rich fibrin was prepared from whole blood of 8 healthy volunteers...
June 23, 2017: Annals of Plastic Surgery
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