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https://www.readbyqxmd.com/read/28340530/effect-of-severe-plastic-deformation-on-structure-and-properties-of-al-sc-ta-and-al-sc-ti-alloys
#1
Alla Berezina, Tetiana Monastyrska, Olexandr Davydenko, Oleh Molebny, Sergey Polishchuk
The comparative analysis of the effect of monotonous and non-monotonous severe plastic deformations (SPD) on the structure and properties of aluminum alloys has been carried out. Conventional hydrostatic extrusion (HE) with a constant deformation direction and equal-channel angular hydroextrusion (ECAH) with an abrupt change in the deformation direction were chosen for the cases of monotonous and non-monotonous SPD, respectively. Model cast hypoeutectic Al-0.3%Sc alloys and hypereutectic Al-0.6%Sc alloys with Ta and Ti additives were chosen for studying...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28340515/inflammatory-potential-of-diet-and-risk-of-oral-and-pharyngeal-cancer-in-a-large-case-control-study-from-italy
#2
Nitin Shivappa, James R Hébert, Valentina Rosato, Werner Garavello, Diego Serraino, Carlo La Vecchia
Diet and inflammation have been suggested to be important risk factors for oral and pharyngeal cancer. We examined the association between dietary inflammatory index (DII) and oral and pharyngeal cancer in a large case-control study conducted between 1992 and 2009 in Italy. This study included 946 cases with incident, histologically confirmed oral and pharyngeal cancer, and 2492 controls hospitalized for acute non-neoplastic diseases. The DII was computed based on dietary intake assessed by a valid 78-item food frequency questionnaire and was adjusted for non-alcohol energy intake using the residual approach (E-DII)...
March 24, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28340507/understanding-the-contribution-of-disulphide-bridges-to-the-folding-and-misfolding-of-an-anti-a%C3%AE-scfv
#3
Laia Montoliu-Gaya, Jose C Martínez, Sandra Villegas
ScFv-h3D6 is a single chain variable fragment that precludes Aβ peptide-induced cytotoxicity by withdrawing Aβ oligomers from the amyloid pathway to the worm-like pathway. Production of scFv molecules is not a straightforward procedure because of the occurrence of disulphide scrambled conformations generated in the refolding process. Here, we separately removed the disulphide bond of each domain and solved the scrambling problem; and then, we intended to compensate the loss of thermodynamic stability by adding three C-terminal elongation mutations previously described to stabilize the native fold of scFv-h3D6...
March 24, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/28340494/postoperative-care-of-patients-with-high-grade-glioma-is-there-a-real-need-for-the-neurocritical-icu-and-early-ct-scan
#4
Roberto Altieri, Fabio Cofano, Alessandro Agnoletti, Riccardo Fornaro, Marco Ajello, Francesco Zenga, Alessandro Ducati, Diego Garbossa
Background Pressure on economic resources now requires a careful rationalization of services. For adult patients with supratentorial gliomas, there is no consensus on the real need for care in a postoperative neurocritical intensive care unit (NICU) and on the timing of a postsurgical computed tomography (CT) scan. In this retrospective nonrandomized study, we assessed if and when there is a real need for NICU and if an early CT scan could be justified in the absence of neurologic worsening. Methods Of 264 patients, 21 were admitted to the NICU after the procedure as planned before the surgery for their clinical features (Karnofsky performance status < 70, American Society of Anesthesiologists score > 2, or Charlson Comorbidity Index > 5)...
March 24, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28340478/different-dna-damage-response-of-cis-and-trans-isomers-of-commonly-used-uv-filter-after-the-exposure-on-adult-human-liver-stem-cells-and-human-lymphoblastoid-cells
#5
Anežka Sharma, Katarína Bányiová, Pavel Babica, Naouale El Yamani, Andrew Richard Collins, Pavel Čupr
2-ethylhexyl 4-methoxycinnamate (EHMC), used in many categories of personal care products (PCPs), is one of the most discussed ultraviolet filters because of its endocrine-disrupting effects. EHMC is unstable in sunlight and can be transformed from trans-EHMC to emergent cis-EHMC. Toxicological studies are focusing only on trans-EHMC; thus the toxicological data for cis-EHMC are missing. In this study, the in vitro genotoxic effects of trans- and cis-EHMC on adult human liver stem cells HL1-hT1 and human-derived lymphoblastoid cells TK-6 using a high-throughput comet assay were studied...
March 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28340449/right-hemisphere-pitch-mismatch-negativity-reduction-in-patients-with-major-depression-an-meg-study
#6
Noriaki Hirakawa, Yoji Hirano, Itta Nakamura, Shogo Hirano, Jinya Sato, Naoya Oribe, Takefumi Ueno, Shigenobu Kanba, Toshiaki Onitsuka
BACKGROUND: The mismatch negativity (MMN) component of the event-related potential and its magnetic counterpart, the MMNm, are generated by a mismatch between the physical features of a deviant stimulus and a neuronal sensory-memory trace produced by repetitive standard stimuli. Deficits in the MMN/MMNm have been reported in patients with major depression; however, the results are inconsistent. The present study investigated the pitch-MMNm in patients with major depression using whole-head 306-channel magnetoencephalography (MEG)...
March 19, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28340428/vaccination-as-a-control-strategy-against-salmonella-infection-in-pigs-a-systematic-review-and-meta-analysis-of-the-literature
#7
REVIEW
M L de la Cruz, I Conrado, A Nault, A Perez, L Dominguez, J Alvarez
Consumption or handling of improperly processed or cooked pork is considered one of the top sources for foodborne salmonellosis, a common cause of intestinal disease worldwide. Asymptomatic carrier pigs may contaminate pork at slaughtering; therefore, pre-harvest reduction of Salmonella load can contribute to reduce public health risk. Multiple studies have evaluated the impact of vaccination on controlling Salmonella in swine farms, but results are highly variable due to the heterogeneity in vaccines and vaccination protocols...
March 11, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28340407/transmission-of-persistent-ionizing-radiation-induced-foci-through-cell-division-in-human-primary-cells
#8
Aurelie Vaurijoux, Pascale Voisin, Amelie Freneau, Joan Francesc Barquinero, Gaetan Gruel
Unrepaired DNA double-strand breaks (DSBs) induced by ionizing radiation are associated with lethal effects and genomic instability. After the initial breaks and chromatin destabilization, a set of post-translational modifications of histones occurs, including phosphorylation of serine 139 of histone H2AX (γH2AX), which leads to the formation of ionizing radiation-induced foci (IRIF). DSB repair results in the disappearance of most IRIF within hours after exposure, although some remain 24h after irradiation...
March 10, 2017: Mutation Research
https://www.readbyqxmd.com/read/28340396/spectral-studies-on-anthracene-based-dual-sensor-for-hg-2-and-al-3-ions-with-two-distinct-output-modes-of-detection
#9
Navneet Kaur, Baljeet Kaur
A simple and easily synthesized colorimetric and fluorescent chemosensor 1, based on aromatic OH and imine moieties as a binding and anthracene as signaling unit, has been synthesized in a one-step procedure. The chemosensor 1 is developed as a dual chemosensor for detection of Hg(2+) and Al(3+) ions in CH3OH, which exhibited a color change from light yellow to dark yellow with Hg(2+) ions, enabling 1 a suitable "bare eye" indicator for Hg(2+) ions. On the other hand, fluorescent enhancement with blue shift along with brilliant cyan fluorescence was observed upon binding with Al(3+) ions...
March 15, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28340321/exploring-the-relationship-between-cognition-and-functional-verbal-reasoning-in-adults-with-severe-traumatic-brain-injury-at-six-months-post-injury
#10
Petra Avramović, Belinda Kenny, Emma Power, Skye McDonald, Robyn Tate, Louise Hunt, Sheila MacDonald, Rob Heard, Leanne Togher
OBJECTIVE(S): This study aims to determine the association between cognitive impairment and functional verbal reasoning in adults with severe traumatic brain injury (TBI), at six months post-injury. METHOD(S): 38 participants with severe TBI were assessed using the four tasks on the Functional Assessment of Verbal Reasoning and Executive Strategies (FAVRES) [1] and a battery of neuropsychological tests at 6 months post injury in a cross-sectional observational study...
March 24, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28340319/apigenin-reduces-nf-%C3%AE%C2%BAb-and-subsequent-cytokine-production-as-protective-effect-in-a-rodent-animal-model-of-lung-ischemia-reperfusion-injury
#11
Ioannis Bougioukas, Vassilios Didilis, Alexander Emmert, Ahmad F Jebran, Regina Waldmann-Beushausen, Tomislav Stojanovic, Friedrich A Schoendube, Bernhard C Danner
PURPOSE: Lung ischemia-reperfusion injury (LIRI) can complicate lung transplantation or cardiac surgery with cardiopulmonary bypass, increasing morbidity and mortality. In LIRI, pro-inflammatory cytokines are activated, reactive oxygen species are generated and nuclear factor-κB (NF-κB) is up-regulated, altering lung mechanics. We tested the effect of the flavonoid apigenin on a rodent model of LIRI. METHODS: Thirty-seven Wistar rats were subjected to LIRI with or without a single or double dose of apigenin...
March 24, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28340259/sedative-prescriptions-are-common-at-opioid-initiation-an-observational-study-in-the-veterans-health-administration
#12
Hilary J Mosher, Kelly K Richardson, Brian C Lund
Background.:  Concurrent use of sedatives, especially anxiolytics, and opioids is associated with increased risk of medication-related harms. To the extent that multiple prescribers are involved, approaches to influence patterns of coprescribing will differ from those to influence prescribing within a single drug class. Objectives.:  Describe the proportion of new opioid recipients with concurrent sedative medications at opioid initiation and determine whether these medications were prescribed by the same prescriber...
March 18, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28340085/prevalence-of-neuropathic-pain-in-patients-with-traumatic-brachial-plexus-injury-a-multicenter-prospective-hospital-based-study
#13
Palma Ciaramitaro, Luca Padua, Grazia Devigili, Eugenia Rota, Stefano Tamburin, Roberto Eleopra, Giorgio Cruccu, Andrea Truini
Objective. : Prevalence and clinical characteristics of neuropathic pain due to traumatic brachial plexus injury. Design. : Observational epidemiological study. Setting. : Hospital-based multicenter study. Subjects. : One hundred seven prospectively enrolled patients with brachial plexus injury. Methods. : All the patients underwent clinical examination and neurophysiological testing for a definitive diagnosis of the brachial plexus lesion...
March 3, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28340027/influence-of-long-term-in-vivo-exposure-debris-accumulation-and-archwire-material-on-friction-force-among-different-types-of-brackets-and-archwires-couples
#14
Uroš Mezeg, Jasmina Primožic
Objective: The aim was to assess the influence of long-term in vivo exposure, debris accumulation and archwire material on static and kinetic friction force among different types of brackets and archwires couples. Material and Methods: Friction testing was performed among four lower incisors' brackets, conventional and self-ligating (SL), coupled with either nickel-titanium or stainless steel archwires, as-received and in vivo exposed in 18 subjects. The friction testing was performed for a sliding distance of 14 mm at a speed of 10 mm/min, with a starting force of 0...
February 28, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28340005/inappropriate-shocks-in-single-chamber-and-subcutaneous-implantable-cardioverter-defibrillators-a-systematic-review-and-meta-analysis
#15
Angelo Auricchio, J Harrison Hudnall, Edward J Schloss, Laurence D Sterns, Takashi Kurita, Albert Meijer, Dedra H Fagan, Tyson Rogers
Aims: Single-chamber (VR-ICD) and subcutaneous (S-ICD) implantable cardioverter-defibrillators are effective to protect patients against sudden death but expose them to higher risk of inappropriate shock (IS). We sought to quantify the annual rate and influencing factors of ISs in VR- and S-ICDs from the literature. Methods and results: PubMed, Embase, and Cochrane Library were searched for full text articles with IS rates. Poisson distribution estimated proportion of patients with ISs; rates were annualized based on follow-up duration...
March 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28340000/effects-of-feeding-original-xpc%C3%A2-to-broilers-with-a-live-coccidiosis-vaccine-under-industry-conditions-part-1-growth-performance-and-salmonella-inhibition
#16
S M Roto, S H Park, S I Lee, P Kaldhone, H O Pavlidis, S B Frankenbach, D R McIntyre, K Striplin, L Brammer, S C Ricke
Supplementation of poultry diets with Diamond V Original XPC™ (XPC) has been proposed as a means to ameliorate the commonly observed loss of appetite and depression of growth in birds given a live coccidiosis vaccine. A study was conducted to compare the effects on bird performance of a live coccidiosis vaccine in broilers, with and without the dietary inclusion of XPC (1.25 g/kg). Ross 708 male broilers (n = 1,280) were allocated to one of 4 feed treatments: cocci-vaccine (T1), cocci-vaccine + XPC (T2), cocci-vaccine + salinomycin in the grower diet only, (T3), and cocci-vaccine + salinomycin in the grower diet + XPC (T4)...
March 3, 2017: Poultry Science
https://www.readbyqxmd.com/read/28339939/developmental-morphology-study-on-the-stomach-of-african-ostrich-chicks
#17
J X Wang, P Li, X T Zhang, L X Ye
This study investigates the developmental morphology changes on the proventriculus and gizzard of African ostrich chicks using gross anatomy, and light and transmission electronic microscopy. The body weight; the weight of the proventriculus and gizzard; the thickness of simple tubular glands, muscularis mucosae, compound tubular glands, and muscular layer of the proventriculus; and the thickness of the gizzard glands and muscularis mucosae were measured on postnatal d one, 45, 90, and 334. Under transmission electronic microscopy, the oxynticopeptic cells, mucous cells, and endocrine cells were observed in the proventriculus on postnatal d one, 45, and 90...
March 2, 2017: Poultry Science
https://www.readbyqxmd.com/read/28339915/the-effect-of-feed-supplementation-with-zakarpacki-zeolite-clinoptilolite-on-percentages-of-t-and-b-lymphocytes-and-cytokine-concentrations-in-poultry
#18
Lukasz Jarosz, Dagmara Stepien-Pysniak, Zbigniew Gradzki, Malgorzata Kapica, Agata Gacek
The available literature lacks information on the effect of Zakarpacki zeolite (clinoptilolite) on the immune system of poultry. Therefore, the aim of this study was to determine the effect of this zeolite on selected indicators of the immune response in poultry by evaluating the expression of cluster of differentiation ( ) surface molecules on T and B lymphocytes and the concentration of IL-2 and IL-10 in the blood. Ninety one-day-old Ross 308 broiler chicks were used in the study. The birds were divided into 3 groups of 30 each...
March 2, 2017: Poultry Science
https://www.readbyqxmd.com/read/28339904/validity-of-different-activity-monitors-to-count-steps-in-an-inpatient-rehabilitation-setting
#19
Daniel Treacy, Leanne Hassett, Karl Schurr, Sakina Chagpar, Serene S Paul, Catherine Sherrington
Background: Commonly used activity monitors have been shown to be accurate in counting steps in active people, however, further validation is needed in slower walking populations. Objectives: To determine the validity of activity monitors for measuring step counts in rehabilitation inpatients compared to visually-observed step counts. To explore the influence of gait parameters, activity monitor position and use of walkers on activity monitor accuracy. Methods: 166 inpatients admitted to a rehabilitation unit with an average walking speed of 0...
March 2, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28339866/relative-biological-value-of-1%C3%AE-hydroxycholecalciferol-to-25-hydroxycholecalciferol-in-broiler-chicken-diets
#20
J C Han, G H Chen, J L Zhang, J G Wang, H X Qu, Y F Yan, X J Yang, Y H Cheng
This study was conducted to evaluate the relative biological value (RBV) of 1α-hydroxycholecalciferol (1α-OH-D3) to 25-hydroxycholecalciferol (25-OH-D3) in one- to 21-day-old broiler chickens fed calcium (Ca)- and phosphorus (P)-deficient diets. On the d of hatch, 450 male Ross 308 broiler chickens were weighed and randomly allotted to 9 treatments with 5 replicates of 10 birds per replicate. The basal diet contained 0.50% Ca and 0.25% non-phytate phosphorus (NPP) but was not supplemented with cholecalciferol (vitamin D3)...
March 1, 2017: Poultry Science
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