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https://www.readbyqxmd.com/read/29166711/-effects-of-caspase-1-inhibitor-vx765-on-cold-restraint-stress-induced-acute-gastric-ulcer-in-mice
#1
S Q Zheng, X D Hong, T S Chen, P F Luo, S C Xiao
Objective: To investigate the protective effects of caspase-1 inhibitor VX765 on gastric mucosa of mice with cold-restraint stress-induced acute gastric ulcer. Methods: Twenty-four specific pathogen free male C57BL/6J mice were divided into normal control group (NC), cold restrain group (CR), VX765 pre-treatment+ cold restrain group (VCR), and rabeprazole pre-treatment+ cold restrain group (RCR) according to the random number table, with 6 mice in each group. Mice in group NC were injected intraperitoneally with solution of 10 mL/kg dimethylsulfoxide (DMSO) and phosphate buffer solution (PBS)...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166710/-effects-of-hydrogen-on-the-lung-damage-of-mice-at-early-stage-of-severe-burn
#2
C Qin, Y X Bian, T T Feng, J H Zhang, Y H Yu
Objective: To investigate the effects of hydrogen on the lung damage of mice at early stage of severe burn. Methods: One hundred and sixty ICR mice were divided into sham injury, hydrogen, pure burn, and burn+ hydrogen groups according to the random number table, with 40 mice in each group. Mice in pure burn group and burn+ hydrogen group were inflicted with 40% total body surface area full-thickness scald (hereafter referred to as burn) on the back, while mice in sham injury group and hydrogen group were sham injured...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166709/-effects-of-dexmedetomidine-on-myocardium-of-rats-with-severe-burn-at-early-stage
#3
D Wang, P L Yang, X Zhang, Y Liu
Objective: To investigate the effects of dexmedetomidine on myocardium of rats at early stage after severe burn. Methods: Twenty specific pathogen free male SD rats were immersed in 90 ℃ hot water for 20 s, causing 30% total body surface area (TBSA) full-thickness scald (hereafter referred to as burn) on the back. And then they were divided into burn resuscitation group (BR) and burn resuscitation+ dexmedetomidine group (BRD) according to the random number table, with 10 rats in each group. Sodium lactate Ringer's solution (2 mL·kg(-1)·%TBSA(-1)) were intraperitoneally injected into rats of both groups after burn...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166708/-effects-of-astragalus-polysaccharide-on-cardiac-dysfunction-in-rabbits-with-severe-scald-injury
#4
L Zhong, J H Zhan, J H Luo, X Cheng
Objective: To investigate the effects of astragalus polysaccharide (AP) on cardiac dysfunction in rabbits with severe scald injury. Methods: Sixty-four New Zealand white rabbits were divided into pure scald group and AP group according to the random number table, with 32 rabbits in each group. Rabbits in the two groups were all inflicted with 30% total body surface area full-thickness scald on the back. Immediately after injury, rabbits in two groups were intraperitoneally injected with lactated Ringer's solution once for antishock...
November 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29166046/fcc-hcp-coexistence-in-dense-thermo-responsive-microgel-crystals
#5
D Karthickeyan, R G Joshi, B V R Tata
Analogous to hard-sphere suspensions, monodisperse thermo-responsive poly (N-isopropyl acrylamide) (PNIPAM) microgel particles beyond a volume fraction (ϕ) of 0.5 freeze into face centered cubic (FCC)-hexagonal close packed (HCP) coexistence under as prepared conditions and into an FCC structure upon annealing. We report here FCC-HCP coexistence to be stable in dense PNIPAM microgel crystals (ϕ > 0.74) with particles in their deswollen state (referred to as osmotically compressed microgel crystals) and the FCC structure with particles in their swollen state by performing annealing studies with different cooling rates...
June 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29165483/ion-chemistry-at-elevated-ion-molecule-interaction-energies-in-a-selected-ion-flow-drift-tube-reactions-of-h3o-no-and-o2-with-saturated-aliphatic-ketones
#6
Anatolii Spesyvyi, David Smith, Patrik Španěl
The reactions of H3O(+), NO(+) and O2(+) ions with a homologous series of six aliphatic ketones, viz. acetone through 2-octanone, have been investigated in a helium-buffered selected ion flow-drift tube, SIFDT, in order to reveal their dependencies on ion-molecule interaction energies, Er, and to gain insight into their mechanisms. The ultimate motivation is to allow analysis and absolute quantification of trace amounts of ketones and other volatile organic compounds in air using selected ion flow-drift tube mass spectrometry, SIFDT-MS...
November 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29164717/antibiotics-reduce-genetic-diversity-of-core-species-in-the-honeybee-gut-microbiome
#7
Kasie Raymann, Louis-Marie Bobay, Nancy A Moran
The gut microbiome plays a key role in animal health, and perturbing it can have detrimental effects. One major source of perturbation to microbiomes, in humans and human-associated animals, is exposure to antibiotics. Most studies of how antibiotics affect the microbiome have used amplicon sequencing of highly conserved 16S rRNA sequences, as in a recent study showing that antibiotic treatment severely alters the species-level composition of the honeybee gut microbiome. But because the standard 16S rRNA-based methods cannot resolve closely related strains, strain-level changes could not be evaluated...
November 22, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/29164397/factors-for-time-to-trastuzumab-induced-cardiotoxicity-in-breast-cancer-patients
#8
Mi Hyung Lee, Jeong Yee, Young Ju Kim, Jin Young Moon, Joo Hee Kim, Sandy Jeong Rhie, Hye Sun Gwak
Trastuzumab is a drug used for the treatment of metastatic breast cancer patients. Due to blockage of the human epidermal growth factor receptor 2 signaling in cardiac myocytes, cardiotoxicity has been observed. There are many studies that investigated risk factors for trastuzumab-induced cardiotoxicity, but no study has been published for factors on the time to cardiotoxicity. This study aimed to investigate the factors for the time to occur trastuzumab-induced cardiotoxicity. From January 2014 to December 2015, a retrospective study was performed with breast cancer patients who were treated with trastuzumab...
November 21, 2017: Medical Oncology
https://www.readbyqxmd.com/read/29164092/the-nuisance-mosquito-anopheles-plumbeus-stephens-1828-in-germany-a-questionnaire-survey-may-help-support-surveillance-and-control
#9
Eva C Heym, Jette Schröder, Helge Kampen, Doreen Walther
The mosquito species Anopheles plumbeus is an aggressive biter and a potential vector of malaria parasites and West Nile virus. It occurs naturally at low population densities, as its larval development is adapted to the specific water qualities found in tree holes. However, probably owing to environmental changes, it has recently been observed in several European countries to use increasingly often artificial breeding habitats that may lead to mass development and severe annoyance to humans living close by...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29164073/streptococcus-equi-subsp-zooepidemicus-invades-and-survives-in-epithelial-cells
#10
Bolette Skive, Manfred Rohde, Gabriella Molinari, Thomas Hartig Braunstein, Anders M Bojesen
Streptococcus equi subsp. zooepidemicus (S. zooepidemicus) is an opportunistic pathogen of several species including humans. S. zooepidemicus is found on mucus membranes of healthy horses, but can cause acute and chronic endometritis. Recently S. zooepidemicus was found able to reside in the endometrium for prolonged periods of time. Thus, we hypothesized that an intracellular phase may be part of the S. zooepidemicus pathogenesis and investigated if S. zooepidemicus was able to invade and survive inside epithelial cells...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29163923/size-and-charge-effect-of-guest-cations-in-the-formation-of-polyoxopalladates-a-theoretical-and-experimental-study
#11
Zhongling Lang, Peng Yang, Zhengguo Lin, Likai Yan, Ming-Xing Li, Jorge J Carbó, Ulrich Kortz, Josep M Poblet
The development of rational synthetic procedures with desired nuclearity and high selectivity is a critical issue in inorganic chemistry. Here we demonstrate a comprehensive understanding of the template effect induced by metal cations in the formation mechanism of the class of polyoxopalladates ({MPd12L8} nanocube and {MPd15L10} nanostar) by combining computational and experimental techniques. The capture of a M (n+) guest ion by a peripheral palladium(ii)-oxo shell leads to a competition between the parent Pd(2+) addenda ion and the respective guest metal ion...
November 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/29163645/hypervitaminosis-d3-in-broiler-chicks-histopathological-immunomodulatory-and-immunohistochemical-approach
#12
R Kumar, R S Brar, H S Banga
The present study was undertaken to investigate the toxic effects of higher doses (1,00,000 IU i.e. 2.5 mg/kg body weight (BW)) of vitamin D3, concomitantly with bacterial endotoxins (lipopolysaccharides: LPS) to study the immunomodulatory potential of vitamin D3 in IBL-80 broiler chicks. The chicks were divided into four groups [group I (NSS), group II (LPS), group III (Vit. D3 + NSS), and group IV (Vit. D3 + LPS)] containing eight chicks in each group, treated accordingly for 21 days. Birds were kept under close observation for apparent clinical signs and symptoms...
2017: Iranian journal of veterinary research
https://www.readbyqxmd.com/read/29163629/high-throughput-field-phenotyping-of-leaves-leaf-sheaths-culms-and-ears-of-spring-barley-cultivars-at-anthesis-and-dough-ripeness
#13
Gero Barmeier, Urs Schmidhalter
To optimize plant architecture (e.g., photosynthetic active leaf area, leaf-stem ratio), plant physiologists and plant breeders rely on destructively and tediously harvested biomass samples. A fast and non-destructive method for obtaining information about different plant organs could be vehicle-based spectral proximal sensing. In this 3-year study, the mobile phenotyping platform PhenoTrac 4 was used to compare the measurements from active and passive spectral proximal sensors of leaves, leaf sheaths, culms and ears of 34 spring barley cultivars at anthesis and dough ripeness...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163623/accession-dependent-cbf-gene-deletion-by-crispr-cas-system-in-arabidopsis
#14
Sungkyung Cho, Si-In Yu, Junghoon Park, Yanfei Mao, Jian-Kang Zhu, Dae-Jin Yun, Byeong-Ha Lee
The CRISPR/Cas system became a powerful genome editing tool for basic plant research and crop improvement. Thus far, CRISPR/Cas has been applied to many plants, including Arabidopsis, rice and other crop plants. It has been reported that CRISPR/Cas efficiency is generally high in many plants. In this study, we compared the genome editing efficiency of CRISPR/Cas in three different Arabidopsis accessions [Col-0, Ler, and C24RDLUC (C24 accession harboring the stress-responsive RD29A promoter-driven luciferase reporter)]...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163613/a-comparison-of-petiole-hydraulics-and-aquaporin-expression-in-an-anisohydric-and-isohydric-cultivar-of-grapevine-in-response-to-water-stress-induced-cavitation
#15
Megan C Shelden, Rebecca Vandeleur, Brent N Kaiser, Stephen D Tyerman
We report physiological, anatomical and molecular differences in two economically important grapevine (Vitis vinifera L.) cultivars cv. Grenache (near-isohydric) and Chardonnay (anisohydric) in their response to water-stress induced cavitation. The aim of the study was to compare organ vulnerability (petiole and stem) to cavitation by measuring ultrasonic acoustic emissions (UAE) and percent loss of conductance of potted grapevines subject to the onset of water-stress. Leaf (ψL) and stem water potential (ψS), stomatal conductance (gs), transpiration (E), petiole hydraulics (KPet), and xylem diameter were also measured...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163594/expression-of-mep-pathway-genes-and-non-volatile-sequestration-are-associated-with-circadian-rhythm-of-dominant-terpenoids-emission-in-osmanthus-fragrans-lour-flowers
#16
Riru Zheng, Cai Liu, Yanli Wang, Jing Luo, Xiangling Zeng, Haiqin Ding, Wei Xiao, Jianping Gan, Caiyun Wang
Osmanthus fragrans Lour. is one of the top 10 traditional ornamental flowers in China famous for its unique fragrance. Preliminary study proved that the terpenoids including ionone, linalool, and ocimene and their derivatives are the dominant aroma-active compounds that contribute greatly to the scent bouquet. Pollination observation implies the emission of aromatic terpenoids may follow a circadian rhythm. In this study, we investigated the variation of volatile terpenoids and its potential regulators. The results showed that both volatile and non-volatile terpenoids presented circadian oscillation with high emission or accumulation during the day and low emission or accumulation during the night...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163591/transcriptomic-and-hormonal-analyses-reveal-that-yuc-mediated-auxin-biogenesis-is-involved-in-shoot-regeneration-from-rhizome-in-cymbidium
#17
Yang Liu, Hai-Liang Zhang, He-Rong Guo, Li Xie, Rui-Zhen Zeng, Xiang-Qian Zhang, Zhi-Sheng Zhang
Cymbidium, one of the most important orchid genera in horticulture, can be classified into epiphytic and terrestrial species. Generally, epiphytic Cymbidium seedlings can be easily propagated by tissue culture, but terrestrial seedlings are difficult to propagate. To date, the molecular mechanisms underlying the differences in the ease with which terrestrial and epiphytic cymbidiums can be propagated are largely unknown. Using RNA-sequencing, quantitative reverse transcription PCR and enzyme-linked immunosorbent assay, Cymbidium 'Xiaofeng' (CXF), which can be efficiently micropropagated, and terrestrial Cymbidium sinense 'Qijianbaimo' (CSQ), which has a low regeneration ability, were used to explore the molecular mechanisms underlying the micropropagation ability of Cymbidium species...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163567/soil-type-has-a-stronger-role-than-dipterocarp-host-species-in-shaping-the-ectomycorrhizal-fungal-community-in-a-bornean-lowland-tropical-rain-forest
#18
Adam L Essene, Katherine L Shek, J D Lewis, Kabir G Peay, Krista L McGuire
The role that mycorrhizal fungal associations play in the assembly of long-lived tree communities is poorly understood, especially in tropical forests, which have the highest tree diversity of any ecosystem. The lowland tropical rain forests of Southeast Asia are characterized by high levels of species richness within the family Dipterocarpaceae, the entirety of which has been shown to form obligate ectomycorrhizal (ECM) fungal associations. Differences in ECM assembly between co-occurring species of dipterocarp have been suggested, but never tested in adult trees, as a mechanism for maintaining the coexistence of closely related tree species in this family...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163306/quantifying-contextual-interference-and-its-effect-on-skill-transfer-in-skilled-youth-tennis-players
#19
Tim Buszard, Machar Reid, Lyndon Krause, Stephanie Kovalchik, Damian Farrow
The contextual interference effect is a well-established motor learning phenomenon. Most of the contextual interference effect literature has addressed simple skills, while less is known about the role of contextual interference in complex sport skill practice, particularly with respect to skilled performers. The purpose of this study was to assess contextual interference when practicing the tennis serve. Study 1 evaluated tennis serve practice of nine skilled youth tennis players using a novel statistical metric developed specifically to measure between-skill and within-skill variability as sources of contextual interference...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29162927/dislocation-multiplications-in-extremely-small-hexagonal-structured-titanium-nanopillars-without-dislocation-starvation
#20
Peng Huang, Qian Yu
"Smaller is stronger" has been commonly observed in cubic structured and hexagonal close-packed (HCP) structured materials. Dislocation starvation phenomenon is highly responsible for the increase of strength at smaller scale in cubic materials. However, by using quantitative in situ transmission electron microscope (TEM) nano-mechanical testing on cylindrical titanium nano-pillars with diameters of ~150 nm but varied orientations and three dimensional dislocation tomography, we found that dislocation nucleation and multiplication dominate the plastic deformation of the nano-pillars with no sign of dislocation starvation, resulting in much better ability of dislocation storage and plastic stability of HCP structured materials at extremely small scale...
November 21, 2017: Scientific Reports
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