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https://www.readbyqxmd.com/read/29752810/a-prospective-study-of-female-genital-chronic-graft-versus-host-disease-symptoms-signs-diagnosis-and-treatment
#1
Eva Smith Knutsson, Yvonne Björk, Anna-Karin Broman, Lotti Helström, Malin Nicklasson, Mats Brune, Karin Sundfeldt
INTRODUCTION: Female genital chronic graft-versus-host disease (cGvHD) is a complication of allogeneic hematopoietic cell transplantation (alloHCT) for blood malignancies. Unattended inflammation and fibrosis in the vulva and vagina may lead to total vaginal stenosis. The course and treatment of genital cGvHD was observed in this population-based prospective study. MATERIAL AND METHODS: Women (n = 41) receiving alloHCT in 2005-2010 were examined before and at 3, 6, 9, 12, 18, 24, 30, and 36 months post-transplant...
May 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29750707/secondary-tumors-of-the-gynecologic-tract-a-clinicopathologic-analysis
#2
Georgia Karpathiou, Celine Chauleur, Sirine Hathroubi, Michel Peoc'h
Although the spread of extragenital tumors to individual female genital tract organs, particularly the ovary, has been much studied, histologic data with regard to secondary tumors involving the whole gynecologic tract are largely lacking. Thus, the aim of the study was to investigate the pathologic and clinical features of these tumors in order to better understand their features. This is a retrospective study of 196 secondary lesions involving the gynecologic tract. The parameters studied were the primary site, its histologic type and grade, the presence of mucous production, the type of secondary involvement, defined as distant metastasis, direct extension or locoregional recurrence, and the time to metastasis...
May 10, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29735819/sexually-transmitted-infections-need-for-extragenital-screening
#3
REVIEW
Jyoti Rawre, Sonu Agrawal, Benu Dhawan
Extragenital infections can occur concurrently with simultaneous urogenital infections. Extragenital sites are believed to serve as hidden reservoirs and play a critical role in their transmission. The etiological relationship of the most widespread Sexually transmitted diseases (STD) pathogen to reproductive tract has long been established, but the distribution to extragenital sites appears to be infrequent and its correlation with the sexual practice still requires to be investigated. Optimal-screening strategies for extragenital infections are largely unknown...
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29697664/-the-increasing-importance-of-extragenital-pathology-in-the-structure-of-maternal-mortality-in-russia
#4
A P Milovanov, A V Dobryakov
OBJECTIVE: to determine the proportion of direct obstetric and indirect extragenital causes of maternal deaths in Russia in recent years. MATERIAL AND METHODS: Official statistical data on maternal mortality in Russia were analyzed according to the criteria of the 10th revision of the International Classification of Diseases and compared with those in European countries and the USA. RESULTS: In the past 10 years, Russia has registered a gradual decline in the single maternal mortality rate: 27...
2018: Arkhiv Patologii
https://www.readbyqxmd.com/read/29662933/endometriosis-a-rare-cause-of-large-bowel-obstruction
#5
Gonçalo Alexandrino, Luís Carvalho Lourenço, Rita Carvalho, Cisaltina Sobrinho, David Valadas Horta, Jorge Reis
Large bowel obstruction can result in significant morbidity and mortality, especially in cases of acute complete obstruction. There are many possible causes, the most common in adults being colorectal cancer. Endometriosis is a benign disease, and the most affected extragenital location is the bowel, especially the rectosigmoid junction. However, transmural involvement and acute occlusion are very rare events. We report an exceptional case of acute large bowel obstruction as the initial presentation of endometriosis...
March 2018: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/29661927/t-independent-ifn%C3%AE-and-b-cells-cooperate-to-prevent-mortality-associated-with-disseminated-chlamydia-muridarum-genital-tract-infection
#6
Taylor B Poston, Catherine M O'Connell, Jenna Girardi, Jeanne E Sullivan, Uma M Nagarajan, Anthony Marinov, Amy M Scurlock, Toni Darville
CD4 T cells and antibody are required for optimal acquired immunity to C. muridarum genital tract infection, and T cell-mediated IFNγ production is necessary to clear infection in the absence of humoral immunity. However, the role of T cell-independent immune responses during primary infection remains unclear. We investigated this question by inoculating wild-type and immune-deficient mice with C. muridarum CM001, a clonal isolate capable of enhanced extragenital replication. Genital inoculation of wild-type mice resulted in transient dissemination to the lungs and spleen that then was rapidly cleared from these organs...
April 16, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/29623213/a-case-of-oropharyngeal-ureaplasma-urealyticum-infection-in-a-human-immunodeficiency-virus-positive-bisexual-male-co-infected-with-human-papilloma-virus-and-treponema-pallidum
#7
Nazneen Arif Suri, Sujeesh Sebastian, Deepika Yadav, Neena Khanna, Benu Dhawan
Introduction: Management strategies for sexually transmitted infections (STIs) in their extragenital forms address Neisseria gonorrhoeae and Chlamydia trachomatis alone; whereas increased rates of isolation of other STI agents have been reported from various parts of the world. Their extragenital presence as a reservoir of infection emphasizes the need to screen and treat them at these sites. Case presentation: A 35-year-old human immunodeficiency virus 1 infected bisexual male presented with urethral discharge and multiple ano-genital warts...
March 2018: JMM Case Reports
https://www.readbyqxmd.com/read/29566881/extragenital-lichen-sclerosus-induced-by-radiotherapy
#8
M Bonfill-Ortí, L Martínez-Molina, R M Penín, J Marcoval
No abstract text is available yet for this article.
March 19, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29538469/test-of-cure-retesting-and-extragenital-testing-practices-for-chlamydia-trachomatis-and-neisseria-gonorrhoeae-among-general-practitioners-in-different-socioeconomic-status-areas-a-retrospective-cohort-study-2011-2016
#9
Juliën N A P Wijers, Geneviève A F S van Liere, Christian J P A Hoebe, Jochen W L Cals, Petra F G Wolffs, Nicole H T M Dukers-Muijrers
BACKGROUND: For Chlamydia trachomatis (CT), a test of cure (TOC) within 3-5 weeks is not recommended. International guidelines differ in advising a Neisseria gonorrhoeae (NG) TOC. Retesting CT and NG positives within 3-12 months is recommended in international guidelines. We assessed TOC and retesting practices including extragenital testing in general practitioner (GP) practices located in different socioeconomic status (SES) areas to inform and optimize local test practices. METHODS: Laboratory data of 48 Dutch GP practices between January 2011 and July 2016 were used...
2018: PloS One
https://www.readbyqxmd.com/read/29530553/-extragenital-endometriosis-parietal-thoracic-diaphragmatic-and-nervous-lesions-cngof-has-endometriosis-guidelines
#10
B Merlot, S Ploteau, A Abergel, C Rubob, C Hocke, M Canis, X Fritel, H Roman, P Collinet
According to some studies, extragenital endometriosis represents 5% of the localisations. Its prevalence seems to be underestimated. The extra pelvic localisation can make the diagnosis more difficult. Nevertheless, the recurrent and catamenial symptomatology can evoke this pathology. Surgery seems to be the unique efficient treatment for parietal lesions. Pain linked to nervous lesions (peripheric and sacral roots) seems to be underestimated and difficult to diagnose because of various localisations. Neurolysis seems to have encouraging results...
March 9, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29527097/clinical-and-genetic-aspects-of-mayer-rokitansky-k%C3%A3-ster-hauser-syndrome
#11
REVIEW
Susanne Ledig, Peter Wieacker
The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome [MIM 277000] is characterised by the absence of a uterus and vagina in otherwise phenotypically normal women with karyotype 46,XX. Clinically, the MRKH can be subdivided into two subtypes: an isolated or type I form can be delineated from a type II form, which is characterised by extragenital malformations. The so-called Müllerian hypoplasia, renal agenesis, cervicothoracic somite dysplasia (MURCS) association can be seen as the most severe phenotypic outcome...
2018: Medizinische Genetik: Mitteilungsblatt des Berufsverbandes Medizinische Genetik E.V
https://www.readbyqxmd.com/read/29507565/high-frequency-ultrasonography-hfus-as-a-useful-tool-in-differentiating-between-plaque-morphea-and-extragenital-lichen-sclerosus-lesions
#12
Rafał Białynicki-Birula, Radomir Reszke, Jacek C Szepietowski
Introduction: Morphea and lichen sclerosus (LS) are chronic inflammatory diseases that may pose a diagnostic challenge for a physician. High-frequency ultrasonography (HFUS) is a versatile diagnostic method utilized in dermatologic practice, allowing monitoring the course of the disease, treatment response and differentiation between certain skin disorders. Aim: To prove the usefulness of HFUS in differentiating between plaque morphea and extragenital LS lesions...
October 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29465747/antibiotics-for-treating-gonorrhoea-in-pregnancy
#13
REVIEW
Gabriella Comunián-Carrasco, Guiomar E Peña-Martí, Arturo J Martí-Carvajal
BACKGROUND: Gonorrhoea is a sexually transmitted infection that is caused by Neisseria gonorrhoeae, and is a major public health challenge today. N gonorrhoeae can be transmitted from the mother's genital tract to the newborn during birth, and can cause gonococcal ophthalmia neonatorum as well as systemic neonatal infections. It can also cause endometritis and pelvic sepsis in the mother. This review updates and replaces an earlier Cochrane Review on antibiotics for treating this infectious condition...
February 21, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29465695/extragenital-chlamydia-and-gonorrhea-in-young-black-men-who-have-sex-with-men-missed-treatment-opportunities-for-human-immunodeficiency-virus-infected-men-who-have-sex-with-men
#14
Leandro Mena, Richard A Crosby, Nicholas Chamberlain
OBJECTIVES: This study of young black men who have sex with men (YBMSM) assessed the prevalence of extragenital chlamydia and gonorrhea among those testing negative for urethral infections, and compared prevalence of both by human immunodeficiency virus (HIV) status. METHODS: A convenience sample of 609 YBMSM was recruited for a cross-sectional study from 2 sexual health clinics located in Jackson, MS. To detect Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG), nucleic acid amplification testing was performed on urine, rectal swabs, and oral swabs...
May 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29465673/healthcare-provider-perceptions-of-a-sexually-transmitted-infection-self-testing-program-in-an-hiv-care-clinic
#15
Susana Tat, Shireesha Dhanireddy, Jeanne M Marrazzo, Lindley A Barbee
BACKGROUND: Sexually transmitted infections (STI) disproportionately affect men who have sex with men (MSM). While clinical practice guidelines recommend routine STI screening of MSM who have high-risk behaviors, extragenital STI testing rates have been low in HIV clinics across the nation. The University of Washington STD Prevention Training Center implemented an STI self-testing program at a large HIV primary care clinic in Seattle, WA to facilitate extragenital STI testing. METHODS: We performed a mixed-methods program evaluation to assess healthcare provider acceptability of the program at nine months post implementation...
November 29, 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29406475/pediatric-emergency-provider-sexually-transmitted-infection-screening-practices-in-adolescents-with-oropharyngeal-or-anorectal-chief-complaints
#16
Courtney Gallagher, Susan S Lee, Frances S Shofer, Cynthia J Mollen, Monika K Goyal, Nadia L Dowshen
OBJECTIVES: Sexually transmitted infections (STIs) may present with oropharyngeal or anorectal symptoms. Little is known about the evaluation of adolescents with these complaints in the pediatric emergency department (PED). This study aimed to determine the frequency of and factors associated with STI consideration and testing in this population. METHODS: Retrospective chart review of patients aged 13 to 18 years who presented to an urban PED with oropharyngeal or anorectal chief complaints between June 2014 and May 2015...
February 5, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29394798/-a-case-of-uterine-body-metastasis-from-sigmoid-colon-adenocarcinoma
#17
Katsuyuki Mayumi, Masanobu Terakura, Takaaki Hori, Masashi Takemura
We report a case of metastatic carcinoma to the uterine body from a colorectal adenocarcinoma. A 73-year-old woman underwent laparoscopic sigmoidectomy for sigmoid colon carcinoma 2 years before. In the following study, her serum carcinoembryonic antigen level was elevated, and a uterine body tumor invading the rectal wall was detected via enhanced computed tomography. Colonoscopic examination revealed an elevated lesion at the rectum, which was diagnosed as an adenocarcinoma. Based on these results, we diagnosed the uterine tumor as metastatic tumor from the colon carcinoma...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29373282/-forensic-medical-examination-of-adolescent-and-adult-victims-of-sexual-assault-or-intimate-partner-violence-who-do-not-complain-to-the-police-an-observational-study-in-seine-saint-denis-france
#18
COMPARATIVE STUDY
Céline Denis, Céline Paret, Patrick Chariot
OBJECTIVES: to identify characteristics of victims of sexual assault or domestic violence who consulted in a Department of Forensic Medicine without a formal complaint to the police. METHODS: observational study (03/01/2014-08/31/2015) of individuals (age>15years) consulting in a Department of Forensic Medicine near Paris, France, after a sexual assault or domestic violence. Among the individuals who were examined in the department of Forensic Medicine, we compared the individuals who had not complained to the police to those who had complained to the police...
January 2018: La Presse Médicale
https://www.readbyqxmd.com/read/29368855/gender-differences-in-genital-lichen-sclerosus
#19
Annarosa Virgili, Alessandro Borghi, Simone Cazzaniga, Anna DI Landro, Luigi Naldi, Sara Minghetti, Maria T Fierro, Anna Verrone, Marzia Caproni, Giuseppe Micali, Valeria Gaspari, Manuela Papini, Vito DI Lernia, Lerica Germi, Giampiero Girolomoni, Anna Belloni Fortina, Serafinella P Cannavò, Roberta Bilenchi, Monica Corazza
BACKGROUND: Studies specifically conducted to assess gender differences in genital lichen sclerosus (GLS) are not available. This multicenter study aimed to identify possible gender-related differences on GLS clinical features, history and course, through collecting data from a large mixed-sex sample of patients. METHODS: This was a cross-sectional study on 729 subjects (53.8% females, 46.2% males) affected with GLS, consecutively observed within a network of 15 Italian dermatology units...
January 24, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29365226/noninfectious-penile-lesions
#20
Joel M H Teichman, Miles Mannas, Dirk M Elston
Noninfectious penile lesions are classified by clinical presentation as papulosquamous (e.g., psoriasis), inflammatory (e.g., lichen sclerosus, lichen nitidus, lichen planus), vascular (e.g., angiokeratomas), or neoplastic (e.g., carcinoma in situ, invasive squamous cell carcinoma). Psoriasis presents as red or salmon-colored plaques with overlying silvery scales, often with extragenital cutaneous lesions. Lichen sclerosus presents as a phimotic, hypopigmented prepuce or glans penis with a cellophane-like texture...
January 15, 2018: American Family Physician
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