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Extragenital

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https://www.readbyqxmd.com/read/29136604/extragenital-malignant-mixed-mesodermal-tumor-a-case-report
#1
Mauro Del Papa, Gabriele D'Amata, Fulvio Manzi, Luca Musmeci, Marco Crovaro, Carlo Buonocore, Gaetano Florio, Andrea Giannetti
INTRODUCTION: Primary malignant mixed mesodermal tumor (MMMt, also called malignant mixed Mullerian tumor and designated in the WHO classification of female genital tract neoplasms as carcinosarcoma) is an infrequent tumor that develops usually in the uterus and more rarely in the ovary. Extragenital tumor, including primary peritoneal MMMt, is an extremely rare and aggressive neoplasm with only few case reported in the literature. PRESENTATION OF CASE: We report a case of a 70-year's old female who presented with nausea and abdominal discomfort for 6 months...
November 9, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29134256/-extragenital-disseminated-infection-with-human-papillomaviruses-therapeutic-response-through-vaccination-with-hpv
#2
L Wiskemann, B Durani, W Hartschuh
A 50-year-old man with widespread manifestation of warts and distinct pruritus for the last 5 years was diagnosed with a reactivated human papillomavirus (HPV) infection by three, genetically verified types (6, 16, 18), which are included in the vaccine Gardasil®. Conventional treatment was not successful, but a rapid and significant reduction of the skin manifestation was observed after vaccination with Gardasil®. To what extent therapy-resistant infections with HPV can be influenced through an active HPV vaccination should be investigated in future trials...
November 13, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29108905/-maternal-deaths-due-to-infectious-cause-results-from-the-french-confidential-enquiry-into-maternal-deaths-2010-2012
#3
A Rigouzzo, V Tessier, L Zieleskiewicz
Over the period 2010-2012, maternal mortality from infectious causes accounted for 5% of maternal deaths by direct causes and 16% of maternal deaths by indirect causes. Among the 22 deaths caused by infection occurred during this period, 6 deaths were attributed to direct causes from genital tract origin, confirming thus the decrease in direct maternal deaths by infection during the last ten years. On the contrary, indirect maternal deaths by infection, from extragenital origin, doubled during the same period, with 16 deaths in the last triennium, dominated by winter respiratory infections, particularly influenza: the 2009-2010 influenza A (H1N1) virus pandemic was the leading cause of indirect maternal mortality by infection during the studied period...
November 3, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29035998/uterine-metastasis-from-gastric-adenocarcinoma-masquerading-as-physiologic-endometrial-uptake-in-fdg-pet-ct
#4
Yutang Yao, Minggang Su, Xiaohong Ou, Yangmei Shen
A 44-year-old woman with newly diagnosed gastric adenocarcinoma by gastroscopy underwent F-FDG PET/CT to evaluate possible metastasis. The images demonstrated intense activity in the region of uterine corpus, as well as greater gastric curvature. Physiologic uptake of endometrium was initially suspected, given the rarity with which extragenital cancers metastasize to the uterus. Ultimately, the endometrium proved to be mucinous adenocarcinoma of gastric origin based on its shared histological features and compatible immunostaining profile...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29034107/high-throughput-testing-of-urogenital-and-extragenital-specimens-for-detection-of-chlamydia-trachomatis-and-neisseria-gonorrhoeae-with-cobas-%C3%A2-ct-ng
#5
Elizabeth M Marlowe, David Hardy, Mark Krevolin, Peter Gohl, Alexander Bertram, Rodney Arcenas, Britta Seiverth, Tanja Schneider, Oliver Liesenfeld
We compared the analytical and clinical performance of cobas(®) CT/NG for use on the Cobas(®) 6800/8800 Systems with the Cobas(®) 4800 CT/NG Test from urogenital and extragenital specimens in over 12,000 specimens from both male and female subjects in Germany and the United States. The analytical sensitivity was ≤40 EB/ml for Chlamydia trachomatis (CT) and ≤1 CFU/ml for Neisseria gonorrhoeae (NG). Using clinical specimens, the overall percent agreement with the Cobas(®) 4800 CT/NG Test was >98.5%...
September 2017: European Journal of Microbiology & Immunology
https://www.readbyqxmd.com/read/29028971/infrequent-testing-of-women-for-rectal-chlamydia-and-gonorrhea-in-the-united-states
#6
Guoyu Tao, Karen W Hoover, Melinda B Nye, Philip J Peters, Thomas L Gift, Barbara A Body
Background: Anal sex is a common sexual behavior among women that increases their risk of acquiring rectal infection with Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC). Methods: We estimated the frequency and positivity of rectal CT and GC tests for women aged 15-60 years performed by a large U.S. commercial laboratory between November 2012 and September 2015. We also estimated the frequency and positivity of pharyngeal and genital specimens also performed on the same date...
October 6, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29025691/morphea-and-extragenital-lichen-sclerosus-et-atrophicus-after-influenza-vaccination
#7
S Requena López, Y Hidalgo García, S Gómez Díez, B Vivanco Allende
No abstract text is available yet for this article.
October 9, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29020330/enhanced-sexually-transmitted-infection-screening-for-mycoplasma-genitalium-in-human-immunodeficiency-virus-infected-us-air-force-personnel
#8
Shilpa Hakre, Rosemary O Casimier, Brooke A Danboise, Sheila A Peel, Nelson L Michael, Paul T Scott, Jason F Okulicz
Three-site genital and extragenital screening for Mycoplasma genitalium in 102 asymptomatic Air Force members with human immunodeficiency virus (HIV) infection revealed 19 (18.6%) cases of M. genitalium, commonly (58%) in rectal samples. Because M. genitalium is associated with both HIV acquisition and transmission, these findings suggest that it should be included in routine screening of HIV-infected individuals for sexually transmitted infections.
August 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28992841/-umbilical-endometriosis-and-tumours-in-umbilicus
#9
Jacob Juel, Sine Holst-Albrechtsen, Daiva Erantaite
Umbilical endometriosis is rare, representing only 0.5-1% of all cases of extragenital endometriosis. In infertile women, endometriosis may be as prevalent as 50%. Numerous differential diagnoses are present, hence the clinical diagnosis of umbilical tumours is intricate. In a 33-year-old woman, an umbilical tumour presented 12 months prior to referral. On referral, no cyclic bleeding was noticed, although intermittent bleeding and soreness of the element were present. Dysmenorrhoea, dyspareunia, intermittent pelvic pain, and three years of infertility were noted...
October 9, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28989927/metastatic-uterine-cancer-looking-as-cervical-fibroid-in-recurrent-breast-cancer-woman-a-case-report
#10
So Young Seo, Jin Yong Shin, Yong Il Ji
Metastasis to the female genital tract from extragenital primary cancer is uncommon. In this case, a 46-year-old woman was diagnosed with invasive lobular carcinoma of the left breast in 2011. She had left breast conserving surgery, chemotherapy, radiation, and hormonal therapy (gosereline and tamoxifen). However, she developed menorrhagia after interruption of hormonal therapy and incidentally, the ultrasonogram of her pelvis showed a solid, large mass in the cervix. It looked like leiomyoma. Because of massive vaginal bleeding requiring multiple blood transfusions, she underwent total hysterectomy with bilateral salpingo-oophorectomy...
September 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28916210/modelling-multi-site-transmission-of-the-human-papillomavirus-and-its-impact-on-vaccination-effectiveness
#11
P Lemieux-Mellouki, M Drolet, M Jit, G Gingras, M Brisson
OBJECTIVE: Previous HPV models have only included genital transmission, when evidence suggests that transmission between several anatomical sites occurs. We compared model predictions of population-level HPV vaccination effectiveness against genital HPV16 infection in women, using a 1) uni-site (genital site), and a 2) multi-site model (genital and one extragenital site). METHODS: We developed a uni-site and a multi-site deterministic HPV transmission model, assuming natural immunity was either site-specific or systemic...
August 25, 2017: Epidemics
https://www.readbyqxmd.com/read/28877032/bowel-endometriosis-a-diagnostic-and-therapeutic-challenge
#12
Beng Kwang Ng, Su Ee Phon, Ani Amelia Zainuddin, Wendy Yin Ling Ng, Nordashima Abd Shukor, Pei Shan Lim
Bowel endometriosis is the most common extragenital manifestation of endometriosis. Clinical suspicion is of utmost importance for achieving its diagnosis. Management of this condition is, however, always challenging to the gynaecologist. We report a case of bowel endometriosis in which the patient presented with dyschezia and haematochezia prior to her menses for the past 2 years. A 44-year-old para two woman presented with worsening dysmenorrhea and dyspareunia. She also experienced dyschezia and haematochezia prior to her menses for the past 2 years...
September 6, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28876291/prevalence-of-gonorrhea-and-chlamydia-testing-by-anatomical-site-among-men-who-have-sex-with-men-in-hiv-medical-care-united-states-2013-2014
#13
Monita R Patel, John T Brooks, Yunfeng Tie, Shikha Garg, Heather Bradley
Fewer than one-third of men who have sex with men were tested for Neisseria gonorrhoeae or Chlamydia trachomatis as part of HIV medical care in the United States in 2013 to 2014, and only 11.6% were tested for either sexually transmitted disease at an extragenital site.
August 22, 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28864538/hospital-costs-and-charges-of-discharge-delays-in-children-hospitalized-for-abuse-and-neglect
#14
Michael Lee, Angela Bachim, Carolyn Smith, Elizabeth A Camp, Marcella Donaruma-Kwoh, Binita Patel
OBJECTIVES: Hospitalizations for child maltreatment cases are longer and costlier than hospitalizations for medically similar nonabuse cases. Some discharges are delayed despite medical clearance because of a lack of safe disposition, increasing the cost of hospitalization. We aim to quantify the additional charges and costs of these delays. METHODS: A retrospective chart review evaluated the dates of medical clearance and clinical characteristics of child protection team inpatient consults from 2012 to 2014 at a 595-bed quaternary-care urban hospital...
September 1, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/28820411/-importance-of-shear-wave-elastography-of-livers-in-practically-healthy-pregnant-women
#15
E Sariyeva, S Salahova, N Bayramov
Pulse-wave elastography (SWE) that is one of the mostly used methods in the recent years holds important place in assessment of liver fibrosis. However there is no exact information on the results of liver elastography in healthy pregnant women in the world literature. The aim of the study was to investigate theSWE parameters of liver elastography in practically healthy pregnant women. The subject of the research was 50 practically healthy pregnant women within 18-45 years old (mean age 27.7±0.7). The pregnant women with genital and extragenital diseases were not included to the research...
July 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28741605/a-rare-case-of-intramural-m%C3%A3-llerian-adenosarcoma-arising-from-adenomyosis-of-the-uterus
#16
Sun-Jae Lee, Ji Y Park
Müllerian adenosarcomas usually arise as polypoid masses in the endometrium of post-menopausal women. Occasionally, these tumors arise in the cervix, vagina, broad and round ligaments, ovaries and rarely in extragenital sites; these cases are generally associated with endometriosis. We experienced a rare case of extraendometrial, intramural adenosarcoma arising in a patient with adenomyosis. A 40-year-old woman presented with sudden-onset suprapubic pain. The imaging findings suggested leiomyoma with cystic degeneration in the uterine fundus...
July 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28704207/the-adult-male-rape-victim-forensic-description-of-a-series-of-57-cases
#17
Michelangelo Bruno Casali, Elisa Palazzo, Alberto Blandino, Alessio Battistini, Francesca Motta, Alessandra Kustermann, Cristina Cattaneo
A retrospective analysis on 57 adult male victims of sexual violence has been performed. Age, nationality and anamnesis of the victims, location of the assault, type of violence, number and identity of the assailants, presence of physical injuries, lapse of time between the assault and the request of medical assistance, and toxicological and semen detection tests were analyzed. Victims were mostly in the 31- to 40-year age group. Ten victims referred themselves as either active homosexuals or bisexuals. Forced oral and/or anal penetration was registered in 86...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28679521/use-of-nucleic-acid-amplification-testing-for-diagnosis-of-extragenital-sexually-transmitted-infections
#18
Lisa A Cosentino, Claire S Danby, Lorna K Rabe, Ingrid Macio, Leslie A Meyn, Harold C Wiesenfeld, Sharon L Hillier
Nucleic acid amplification testing (NAAT) is the preferred method to detect Chlamydia trachomatis and Neisseria gonorrhoeae, but no commercial tests are cleared by the U.S. Food and Drug Administration for use with extragenital swab samples. This study evaluated the performance of the Gen-Probe Aptima Combo2 assay (Aptima) and the Cepheid Xpert CT/NG assay (Xpert) to detect C. trachomatis and N. gonorrhoeae in rectal and pharyngeal samples from 224 men and 175 women reporting a history of anal receptive sexual intercourse...
September 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28633746/extragenital-bullous-lichen-sclerosus-on-the-anterior-lower-extremities-report-of-a-case-and-literature-review
#19
Nichelle Arnold, Mitch Manway, Sean Stephenson, Howard Lipkin
Lichen sclerosus (LS) is a benign, chronic, inflammatory skin disease with a predilection for the anogenital region in women. Although males can also be affected, the ratio of female to male incidence has been reported to be as high as 6-10:1 and possesses a bimodal age distribution of pre-pubertal girls and postmenopausal women [1, 2]. Affected skin usually demonstrates polygonal papules that coalesce into porcelain white plaques and can be associated with edema, telangiectasias, and comedo-like plug formation [3]...
June 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28633743/lichen-sclerosus-et-atrophicus-atypical-case-simulating-lichen-planus
#20
Rafaella C Olinger, Joseph L Jorizzo, Felipe B Cerci
Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory dermatosis, characterized by shiny, atrophic, hypochromic papules with a predilection for the genital and perineal skin. Extragenital involvement may occur, but is rare in the isolated form. LSA more commonly affects prepubertal and postmenopausal women. We describe an unusual case of isolated extragenital LSA, restricted to the wrists and mimicking lichen planus.
June 15, 2017: Dermatology Online Journal
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