Juan Jakez-Ocampo, Carmen María Paulín-Vera, Liliana Rivadeneyra-Espinoza, Diana Gómez-Martín, Eduardo Carrillo-Maravilla, Guadalupe Lima, María Inés Vargas-Rojas, Beatriz Pérez-Romano, Gabriella Calva-Cevenini, Mario García-Carrasco, Alejandro Ruiz-Argüelles, Luis Llorente
Objective: We investigated the proportion of Vβ T cell receptor (TCR) gene expression in peripheral CD3+ lymphocytes in familial and non-familial systemic lupus erythematosus (SLE) patients. Method: The Vβ TCR repertoire was studied in 14 families in which several members had SLE. The Vβ TCR usage in SLE patients (n = 27) was compared with that in healthy members of these multiplex families (n = 47), in 37 sporadic SLE patients who had no relatives with SLE, and in 15 healthy unrelated controls...
2018: Gaceta Médica de México