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https://www.readbyqxmd.com/read/28635514/effects-of-thyroid-hormone-therapy-on-cut-surface-healing-of-the-remnant-stomach-with-short-term-weight-loss-alterations-after-sleeve-gastrectomy
#1
Suleyman Orman, Kerem Karaman, Banu Isbilen Basok, Ucler Kisa, Ayse Bahar Ceyran, Erdal Birol Bostanci
BACKGROUND: The hypothalamic-pituitary-tyhroid axis is directly affected by drastic changes in energy stores. The aim of the present study was to determine the effects of triiodothyronine (T3) treatment on cut-surface healing of remnant stomach with weight loss alterations after sleeve gastrectomy (SG). METHODS: Thirty male Wistar Albino rats were divided into three groups: sham (n = 6), control (n = 12), and experimental (n = 12). Control and experimental group rats underwent sleeve gastrectomy...
February 16, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28626257/multi-center-rater-blinded-study-of-early-intervention-with-the-hand-incubator-for-breast-cancer-related-lymphedema-the-beat-edema-trial-proposal-of-a-research-protocol
#2
Hisao Ishii, Katsuyuki Iwatsuki, Masahiro Tatebe, Hitoshi Hirata, Toyone Kikumori, Nobuyuki Tsunoda, Ikuo Hyodo, Tomoko Ogawa, Naoki Unno
Postoperative lymphedema is considered irreversible once it has developed, and significantly lowers the patient's quality of life. However, lymphatic function has recently been clarified, and it is possible that lymphedema can be cured if early treatment is started. This two-arm randomized clinical trial (UMIN000026124) will prospectively evaluate 24 patients with early-stage breast cancer-related lymphedema at the Nagoya University Hospital and Aichi Cancer Center Hospital. The eligibility criteria will be patients who are diagnosed with stage 0-1 breast cancer-related lymphedema, as defined by the International Society of Lymphology, within 12 weeks after breast cancer surgery...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28621671/association-study-of-inflammatory-cytokine-and-chemokine-expression-in-hand-foot-and-mouth-disease
#3
Wenzhong Shang, Suying Qian, Lijuan Fang, Yong Han, Cuiping Zheng
OBJECTIVE: To determine the relationship of cytokine/chemokine expression with the clinical presentation of hand, foot and mouth disease (HFMD). RESULTS: All cytokine/chemokine levels were higher in severe HFMD patients than in mild HFMD patients or controls (P < 0.01). RANTES, MCP-1, IL-4, IL-12 and IL-18 levels were higher in mild HFMD patients than in the controls (P < 0.05). In severe HFMD, all levels (except IL-8 and IL-4) were higher in patients with encephalitis plus pulmonary edema than in those with encephalitis alone (P < 0...
June 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28602490/ultrasound-findings-on-hands-and-wrists-of-patients-with-systemic-lupus-erythematosus-relationship-with-physical-examination
#4
Carolina Freitas Lins, Daniel Lima de Sá Ribeiro, Willer Gonçalves Dourado Santos, Genevievi Rosa, Viviane Machicado, Ana Luisa Pedreira, Emanuela Pimenta da Fonseca, Anna Paula Mota Duque Sousa, Carla Baleeiro Rodrigues Silva, Marcos Antonio Almeida Matos, Mittermayer Barreto Santiago
Diagnosis of synovitis/tenosynovitis by physical examination can be difficult. Ultrasound (US) can be an effective tool for the evaluation of joint involvement in systemic lupus erythematosus (SLE). This study will describe musculoskeletal findings by US in SLE patients and the evaluation of their correlation with physical examination. SLE patients underwent clinical/sonographic evaluation of hand/wrists. In total, 896 joints were evaluated: at least 1 change on physical examination was found in 136 joints and at least 1 US abnormality was found in 65 of 896 joints...
June 8, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28597812/microbial-impact-on-host-metabolism-opportunities-for-novel-treatments-of-nutritional-disorders
#5
Hubert Plovier, Patrice D Cani
Malnutrition is the cause of major public health concerns worldwide. On the one hand, obesity and associated pathologies (also known as the metabolic syndrome) affect more than 10% of the world population. Such pathologies might arise from an elevated inflammatory tone. We have discovered that the inflammatory properties of high-fat diets were linked to the translocation of lipopolysaccharide (LPS). We proposed a mechanism associating the gut microbiota with the onset of insulin resistance and low-grade inflammation, a phenomenon that we called "metabolic endotoxemia...
June 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28573719/n-nitrosamines-induced-infertility-and-hepatotoxicity-in-male-rabbits
#6
S A Sheweita, Y Y El Banna, M Balbaa, I A Abdullah, H E Hassan
N-nitrosamines are widely spread environmental pollutants of well-known toxicity and carcinogenicity in various animal species. These compounds are metabolically activated by cytochrome P450 system predominantly in the liver and in other tissues into more active metabolites leading to generation of both alkylating agents that alkylate DNA and reactive oxygen species. In the current study, we investigated the influence of four types of N-nitrosamines that are commonly present in the environment [methyethylnitrosamine, (MEN), diethylnitrosamine (DEN), diphenylnitroasamine (DPN) and dimethylnitrosamine (DMN)] on both livers and testes of male rabbits through assessment of 17 β-hydroxysteroid dehydrogenase (17 β-HSD) activity...
June 2, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28570460/lesions-associated-with-calcium-gluconate-extravasation-presentation-of-5-clinical-cases-and-analysis-of-cases-published
#7
Francisco Javier Pacheco Compaña, José Midón Míguez, Francisco Javier de Toro Santos
INTRODUCTION: Calcium gluconate extravasation is a process, which, while not common, occurs more frequently in neonatal intensive care units. The aim of this study is to present a number of cases of calcium gluconate extravasation, which have occurred in our hospital, and to carry out a review of those clinical cases published in the literature to obtain relevant epidemiological data. METHODS: Data were gathered on the medical histories of 5 patients who presented lesions secondary to calcium gluconate extravasation in our center...
May 31, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28570442/localized-arm-volume-index-a-new-method-for-body-type-corrected-evaluation-of-localized-arm-lymphedematous-volume-change
#8
Takumi Yamamoto, Nana Yamamoto, Hidehiko Yoshimatsu
BACKGROUND: Volume measurement is a common evaluation for upper extremity lymphedema. However, volume comparison between different patients with different body types may be inappropriate, and it is difficult to evaluate localized limb volume change using arm volume. METHODS: Localized arm volumes (Vk, k = 1-5) and localized arm volume indices (LAVIk) at 5 points (1, upper arm; 2, elbow; 3, forearm; 4, wrist; 5, hand) of 106 arms of 53 examinees with no arm edema were calculated based on physical measurements (arm circumferences and lengths and body mass index [BMI])...
May 31, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28565759/oral-administration-of-ampelopsin-protects-against-acute-brain-injury-in-rats-following-focal-cerebral-ischemia
#9
Xiao-Li Ye, Ling-Qun Lu, Wei Li, Qi Lou, Hong-Gang Guo, Qiao-Juan Shi
Ampelopsin (AMP) is isolated from the Chinese medicinal herb Ampelopsis grossedentata (Hand-Mazz) and has been associated with numerous biological and pharmacological activities. However, it is not clear whether AMP has a direct protective effect on cerebral ischemia reperfusion injury. Therefore, the present study investigated its role in acute brain injury following focal cerebral ischemia in rats. The current study induced transient focal cerebral ischemia by performing middle cerebral artery occlusion (MCAO) for 60 min, followed by 24 h of reperfusion...
May 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28552869/foreign-accent-syndrome-caused-by-the-left-precentral-infarction-a-case-report
#10
Haruki Tokida, Yuji Shiga, Yutaka Shimoe, Shigeru Yamori, Akio Tanaka, Masaru Kuriyama
A 57-year-old right-handed man was admitted to our hospital because of right facial paresis and acute-onset dysarthria. He presented with non-fluent aphasia. His aphasia gradually improved, but he started speaking with a strange accent and intonation from the fifth hospital day. He was diagnosed with foreign accent syndrome (FAS), which lasted for 2 months. MRI revealed ischemic infarction with edema in the superior, middle, and inferior parts of the left precentral gyrus. One year later, MRI revealed old, small infarct lesions in the left precentral gyrus, middle frontal gyrus, and postcentral gyrus...
May 26, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/28549731/clinical-and-sonographic-biomarkers-of-structural-damage-progression-in-ra-patients-in-clinical-remission-a-prospective-study-with-12-months-follow-up
#11
Julio Ramírez, José Antonio Narváez, Virginia Ruiz-Esquide, Javier Hernández-Gañán, Andrea Cuervo, José Inciarte-Mundo, Maria Victoria Hernández, Miguel Sampayo-Cordero, José Luis Pablos, Raimon Sanmartí, Juan D Cañete
OBJECTIVE: To determine clinical and sonographic biomarkers predicting structural damage progression at 12 months of follow-up as measured by magnetic resonance imaging (MRI) in rheumatoid arthritis (RA) patients in clinical remission. PATIENTS AND METHODS: We included patients with RA in clinical remission, defined as 28-joint disease activity score (DAS28)-erythrocyte sedimentation rate (ESR) <2.6 for >6 months. Ultrasound scans of both hands and knees and MRI of the dominant hand were performed at baseline and at 12 months...
May 1, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28537569/inguinal-pain-syndrome-the-influence-of-intraoperative-local-administration-of-0-5-bupivacaine-on-postoperative-pain-control-following-lichtenstein-hernioplasty-a-prospective-case-control-study
#12
Bartosz Cybułka
With current technological advancement and availability of synthetic materials used in inguinal hernia repair, a recurrence after first intervention is not a common and important adverse event. On the other hand, however, some patients complain about chronic pain of the operated site after surgeries using a polypropylene mesh. Many patients are constrained to a prolonged use of analgesics and increased frequency of control visits, which may eventually result in loss of trust in the operator. Every surgical intervention is associated with the risk of immediate or delayed complications...
April 30, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28536986/evaluation-of-anti-inflammatory-and-ulcerogenic-potential-of-zinc-ibuprofen-and-zinc-naproxen-complexes-in-rats
#13
Magdalena Jarosz, Natalia Szkaradek, Henryk Marona, Gabriel Nowak, Katarzyna Młyniec, Tadeusz Librowski
Because of numerous indications and high availability, non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed and used medicines in the world. However, long-term therapy with and improper use of NSAIDs may lead to gastrointestinal damage. Therefore, improving the therapeutic index of the existing drugs has become a priority over the past decades. Considerable attention in the field has been concentrated on metal complexes of non-steroidal anti-inflammatory drugs. The aim of this study is to evaluate the effect of complexation with zinc on the anti-inflammatory and ulcerogenic effects of ibuprofen and naproxen after single and triple intragastric administration to rats...
May 23, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/28522185/orofacial-complex-regional-pain-syndrome-pathophysiologic-mechanisms-and-functional-mri
#14
Yeon-Hee Lee, Kyung Mi Lee, Hyug-Gi Kim, Soo-Kyung Kang, Q-Schick Auh, Jyung-Pyo Hong, Yang-Hyun Chun
Complex regional pain syndrome (CRPS) is one of the most challenging chronic pain conditions and is characterized by burning pain, allodynia, hyperalgesia, autonomic changes, trophic changes, edema, and functional loss involving mainly the extremities. Until recently, very few reports have been published concerning CRPS involving the orofacial area. We report on a 50-year-old female patient who presented with unbearable pain in all of her teeth and hypersensitivity of the facial skin. She also reported intractable pain in both extremities accompanied by temperature changes and orofacial pain that increased when the other pains were aggravated...
March 14, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28511679/evaluation-of-anti-inflammatory-and-gastric-anti-ulcer-activity-of-phyllanthus-niruri-l-euphorbiaceae-leaves-in-experimental-rats
#15
Ronia Mostofa, Shanta Ahmed, Mst Marium Begum, Md Sohanur Rahman, Taslima Begum, Siraj Uddin Ahmed, Riazul Haque Tuhin, Munny Das, Amir Hossain, Manju Sharma, Rayhana Begum
BACKGROUND: The medicinal plants signify a massive basin of potential phytoconstituents that could be valuable as a substitute to allopathic drugs or considered as an analogue in drug development. Phyllanthus niruri L. (Euphorbiaceae) is generally used in traditional medicine to treat ulcer and inflammation. In this project we investigated the methanolic extract of leaves of Phyllanthus niruri for anti-inflammatory and anti-ulcer activity. METHODS: The anti-inflammatory activity of methanol extract of Phyllanthus niruri leaves was evaluated at the doses of 100, 200 and 400 mg/kg, p...
May 16, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28492435/clinical-findings-of-eyes-with-macular-edema-associated-with-branch-retinal-vein-occlusion-refractory-to-ranibizumab
#16
Taiji Hasegawa, Taizo Kawano, Ichiro Maruko, Hideki Koizumi, Tomohiro Iida
PURPOSE: To determine the relationship between the clinical findings and the response to ranibizumab therapy in eyes with macular edema associated with branch retinal vein occlusion. METHODS: We reviewed the medical records of 68 patients with macular edema associated with a branch retinal vein occlusion. The patients were placed in the refractory group if the central foveal thickness remained more than 250 μm throughout the 6-month study period despite the ranibizumab therapy; otherwise, they were placed in the responsive group...
May 10, 2017: Retina
https://www.readbyqxmd.com/read/28489032/clinical-significance-and-prognostic-effect-of-serum-25-hydroxyvitamin-d-concentrations-in-critical-and-severe-hand-foot-and-mouth-disease
#17
Hong-Xing Dang, Cheng-Jun Liu, Jing Li, Shi-Jiao Chen, Feng Xu
OBJECTIVE: To examine the association of serum 25-hydroxyvitamin D [25(OH)D] concentrations with critical and severe hand, foot and mouth disease (HFMD) and assess the clinical significance and prognostic effect of 25(OH)D concentrations in children with HFMD. METHODS: This is a prospective observational study. The 138 children with HFMD were divided into common (49 cases), severe (52 cases), and critical (37 cases) HFMD groups. Another 59 healthy children undergoing outpatient medical examinations during the same period were chosen as the control group...
May 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28480384/evaluation-of-effectiveness-in-a-novel-wound-healing-ointment-crocodile-oil-burn-ointment
#18
Hua-Liang Li, Yi-Tao Deng, Zi-Ran Zhang, Qi-Rui Fu, Ya-Hui Zheng, Xing-Mei Cao, Jing Nie, Li-Wen Fu, Li-Ping Chen, You-Xiong Xiong, Dong-Yan Shen, Qing-Xi Chen
BACKGROUND: Crocodile oil and its products are used as ointments for burns and scalds in traditional medicines. A new ointment formulation - crocodile oil burn ointment (COBO) was developed to provide more efficient wound healing activity. The purpose of the study was to evaluate the burn healing efficacy of this new formulation by employing deep second-degree burns in a Wistar rat model. The analgesic and anti-inflammatory activities of COBO were also studied to provide some evidences for its further use...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28471901/right-hand-weakness-and-headache-during-ascent-to-mount-everest-a-case-of-cerebral-venous-infarction
#19
Jeong Hee Kim, Soo Jeong Kim, Hahn Young Kim
INTRODUCTION: The increasing popularity of trekking in alpine regions has drawn attention to high altitude-associated health concerns. CASE REPORT: Here, we report a case of cerebral venous infarction as a consequence of a hypercoagulable state induced by secondary polycythemia as an adaptation to high altitude. CONCLUSIONS: When patients present focal neurological symptoms such as hemiparesis in addition to symptoms of acute mountain sickness or high-altitude cerebral edema such as headache, nausea, vomiting, and dizziness, cerebral venous infarction should be considered...
May 2017: Neurologist
https://www.readbyqxmd.com/read/28468063/-health-related-quality-of-life-on-severe-hand-foot-and-mouth-disease-patients
#20
Y M Zheng, J Yang, Q H Liao
Objective: To evaluate the health related quality of life (HRQoL) for severe hand, foot and mouth disease (HFMD) patients with different complications. Methods: A national telephone interview under the EQ-5D proxy2 questionnaire (EQ-SD and EQ-VAS), was conducted to obtain the HRQoL of lab-confirmed severe HFMD patients, aged between six months and five-year-olds from the national communicable disease surveillance system from January 1, 2012 to December 31, 2013. Results: A total of 685 severe HFMD cases were included in the study...
April 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
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