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Mitral click

Martina Perazzolo Marra, Cristina Basso, Manuel De Lazzari, Stefania Rizzo, Alberto Cipriani, Benedetta Giorgi, Carmelo Lacognata, Ilaria Rigato, Federico Migliore, Kalliopi Pilichou, Luisa Cacciavillani, Emanuele Bertaglia, Anna Chiara Frigo, Barbara Bauce, Domenico Corrado, Gaetano Thiene, Sabino Iliceto
BACKGROUND: Arrhythmic mitral valve prolapse (MVP) is characterized by myxomatous leaflets and left ventricular (LV) fibrosis of papillary muscles and inferobasal wall. We searched for morphofunctional abnormalities of the mitral valve that could explain a regional mechanical myocardial stretch. METHODS AND RESULTS: Thirty-six (27 female patients; median age: 44 years) arrhythmic MVP patients with LV late gadolinium enhancement on cardiac magnetic resonance and no or trivial mitral regurgitation, and 16 (6 female patients; median age: 40 years) MVP patients without LV late gadolinium enhancement were investigated by morphofunctional cardiac magnetic resonance...
August 2016: Circulation. Cardiovascular Imaging
Ana Gavrovska, Goran Zajić, Vesna Bogdanović, Irini Reljin, Branimir Reljin
Healthy versus unhealthy heart sound computer-aided classification tools are very popular for supporting clinical decisions. In this paper a new method is proposed for the classification of heart sound recordings from a statistical standpoint without detection and localization of fundamental heart sounds (S1, S2). This study analyzes the possibility of detecting healthy heart sound signal from a large set of measurements, corresponding to different pathologies, such as aortic regurgitation, mitral regurgitation, aortic stenosis and ventricular septal defects...
September 2016: Physiological Measurement
Masoud Motasaddi Zarandy, Mohammad Jafar Mahmoudi, Iran Malekzadeh, Sevil Nasirmohtaram
INTRODUCTION: Hearing impairment is the most frequent sensorial congenital defect in newborns and has increased to 2-4 cases per 1,000 live births. Sensory-neural hearing loss (SNHL) accounts for more than 90% of all hearing loss. This disorder is associated with other congenital disorders such as renal, skeletal, ocular, and cardiac disorders. Given that congenital heart diseases are life-threatening, we decided to study the frequency of congenital heart diseases in children with congenital sensory-neural deafness...
March 2016: Iranian Journal of Otorhinolaryngology
Cem Yasar Sanhal, Ozgur Kara, Aykan Yucel
OBJECTIVE: To investigate fetal left ventricular function using the left ventricular modified myocardial performance index (mod-MPI) and E wave/A wave peak velocity (E/A) ratio, and to explore the success of mod-MPI in the prediction of adverse perinatal outcomes in intrahepatic cholestasis of pregnancy (ICP). METHODS: Forty-one ICP cases were compared with 41 gestational age matched healthy controls. Opening and closing clicks of the mitral and aortic valves were used to define the three time periods (ejection time (ET), isovolumetric contraction time (ICT) and isovolumetric relaxation time (IRT)), which were employed in the calculation of mod-MPI (mod-MPI = (ICT+IRT)/ET)...
May 17, 2016: Journal of Maternal-fetal & Neonatal Medicine
Pankaj Saxena, Joseph F Malouf, Roger Click, Rakesh M Suri
Herein, we present a patient who underwent successful repair of failed mitral valve repair in whom intraoperative 3D transesophageal echocardiography provided accurate assessment of the mechanism of mitral regurgitation. In addition, we review the potential advantages and limitations of 3D echocardiography and its role in cardiac surgery.
January 2014: Journal of Cardiac Surgery
L Sanapo, O M Turan, S Turan, J Ton, M Atlas, A A Baschat
OBJECTIVE: To examine the relationships between the ductus venosus (DV) pulsatility index for veins (PIV), individual DV velocity ratios and diastolic and global myocardial cardiac function. METHODS: Doppler measurements of the DV, atrioventricular (AV) valves and ventricular in- and outflow were analyzed. The DV-PIV and velocity ratios for individual phases (systole (S), end-systolic relaxation (v), early diastole (D), atrial systole (a), and S/v, S/D, S/a, v/D, v/a and D/a ratios) were calculated...
May 2014: Ultrasound in Obstetrics & Gynecology
Ana Gavrovska, Goran Zajić, Irini Reljin, Branimir Reljin
Phonocardiography has shown a great potential for developing low-cost computer-aided diagnosis systems for cardiovascular monitoring. So far, most of the work reported regarding cardiosignal analysis using multifractals is oriented towards heartbeat dynamics. This paper represents a step towards automatic detection of one of the most common pathological syndromes, so-called mitral valve prolapse (MVP), using phonocardiograms and multifractal analysis. Subtle features characteristic for MVP in phonocardiograms may be difficult to detect...
2013: Computational and Mathematical Methods in Medicine
Mohammad Q Najib, Hartzell V Schaff, Jhansi Ganji, Howard R Lee, Roger L Click, D Craig Miller, Hari P Chaliki
Osteogenesis imperfecta (OI) or "brittle bone disease" is a rare connective tissue hereditary disorder. The most common clinical presentation of OI is bone fractures. OI also involves extraskeletal structures; however, cardiovascular manifestations are rare. In this report, we describe the cardiovascular anomalies of patients with OI who underwent valve surgery and review the literature on this subject.
March 2013: Journal of Cardiac Surgery
N Meriki, A W Welsh
OBJECTIVES: To construct gestational age-adjusted reference ranges of the left fetal modified myocardial performance index (Mod-MPI) in the Australian population and assess the influence of valve click caliper position on constituent time intervals and the Mod-MPI. METHODS: This is a prospective longitudinal study of 117 normal singleton fetuses undergoing 318 ultrasound scans at 4-6 weekly intervals between 18 and 38 weeks of gestation. The isovolumetric contraction time (ICT), isovolumetric relaxation time (IRT), and ejection time (ET) were measured at 3 different caliper positions in each fetus: beginning of the original valve clicks ('original'), beginning of the reflected valve clicks ('reflected'), and peak of valve clicks ('peak')...
2012: Fetal Diagnosis and Therapy
R Cruz-Martínez, F Figueras, M Bennasar, R García-Posadas, F Crispi, E Hernández-Andrade, E Gratacós
OBJECTIVE: To establish normal reference intervals of the fetal left modified myocardial performance index (MPI) with the use of stringent criteria for delimitation of the time periods. STUDY DESIGN: A cohort of consecutive singleton fetuses was created including at least 20 fetuses for each completed week of gestation between 11 and 41 weeks. The isovolumetric contraction time (ICT), isovolumetric relaxation time (IRT), and ejection time (ET) were calculated using the clicks of the mitral and aortic valves as landmarks, and the MPI was calculated as follows: (ICT + IRT)/ET...
2012: Fetal Diagnosis and Therapy
Mohammad Q Najib, Hari P Chaliki, Satya S Vittala, Amol Raizada, Roger L Click
No abstract text is available yet for this article.
June 2012: Annals of Thoracic Surgery
Dennis J Trafny, Lisa M Freeman, Barret J Bulmer, John M MacGregor, John E Rush, Kathryn M Meurs, Mark A Oyama
OBJECTIVES: In order to more fully understand degenerative mitral valve disease (DMVD) in the Norfolk terrier, we sought to characterize findings from the physical and echocardiographic examination; biochemical, biomarker, and nutritional profiles; and select environmental variables from a cohort of apparently healthy Norfolk terriers. ANIMALS, MATERIALS AND METHODS: Overtly healthy Norfolk terriers ≥ 6 yrs old were recruited by 3 different veterinary hospitals and underwent historical, physical, electrocardiographic (ECG), and 2D/color-flow Doppler echocardiographic examinations...
March 2012: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Anita Hamela-Olkowska, Joanna Szymkiewicz-Dangel
OBJECTIVE: To establish the values of the pulsed Doppler myocardial performance index (MPI, Tei index) for the left and the right ventricle in normal fetuses at 18 to 40 weeks gestation. MATERIAL AND METHODS: Echocardiography exams were performed in 140 normal fetuses at 18 to 40 weeks gestation at the tertiary centre for fetal cardiology MPI was calculated in pulsed Doppler using formula: (a-b)/b. The time a was measured from a closure click to the subsequent opening click of the mitral/tricuspid valve and time b from opening to the closure clicks of the aortic/pulmonary valve...
February 2011: Ginekologia Polska
E L Fallen
The presence of an isolated midsystolic click and/or late systolic murmur in an otherwise healthy young individual is a totally benign entity and represents a normal variation of mitral valve motion and function. There exists a very small subset of patients with mitral prolapse easily identified by certain clinical characteristics, who have distinct pathologic changes in their mitral valve leaflets and supporting structures. (Can Fam Physician 1981; 27:631-634).
April 1981: Canadian Family Physician Médecin de Famille Canadien
Pravin M Shah
Although mitral valve prolapse as a disease entity has been recognized for over 50 years, its precise definition has been elusive. Initial reports based the diagnosis on auscultatory findings (late systolic click - murmur), with left ventricular angiography as a confirmative test. Echocardiography, first the M-mode, and subsequently the two-dimensional, became the dominant diagnostic modality. However, the early reports did not distinguish between billowing valve and flail valve. The advent of surgical repair techniques provided a different perspective; the surgical definition of mitral valve prolapse is often different from that of cardiologists...
September 2010: Journal of Cardiology
Hector I Michelena, Martin D Abel, Rakesh M Suri, William K Freeman, Roger L Click, Thoralf M Sundt, Hartzell V Schaff, Maurice Enriquez-Sarano
Intraoperative (IO) transesophageal echocardiography (TEE) is widely used for assessing the results of valvular heart disease (VHD) surgery. Epiaortic ultrasonography (EAU) has been recommended for prevention of perioperative strokes. To what extent does high-quality evidence justify the widespread use of these imaging modalities? In March 2009, we searched MEDLINE (PubMed and OVID interfaces) and EMBASE for studies published in English using database-specific controlled vocabulary describing the concepts of IOTEE, cardiac surgery, VHD, and EAU...
July 2010: Mayo Clinic Proceedings
E Joy
In most people, mitral valve prolapse, which affects women more than men, is a benign condition with few or no symptoms. But in some patients it poses a significant problem. Potential sequelae include endocarditis, serious arrhythmia, and sudden death. Although a midsystolic click followed by a late systolic murmur is characteristic, definitive diagnosis requires echocardiography. Treatment ranges from education and reassurance in those who have mild disease to valve replacement in severe cases. Most athletes who have mitral valve prolapse can safely participate in all activities...
July 1996: Physician and Sportsmedicine
M A Salim, B S Alpert
Marfan syndrome is an autosomal dominant disorder of the connective tissues. Its major manifestations are in the cardiovascular, musculoskeletal, and ocular systems. Recognizing the phenotypic presentation of tall stature, long limbs and fingers, chest deformity, myopia, midsystolic click, and systolic or diastolic murmur can lead to early diagnosis. Morbidity and mortality are primarily caused by cardiovascular involvement. The goal of medical therapy is to retard the aortic root dilation that leads to sudden death from dissection or rupture...
May 2001: Physician and Sportsmedicine
Ahmet L Orhan, Nurten Sayar, Zekeriya Nurkalem, Nevzat Uslu, Ismail Erdem, Emine C Erdem, Hatice B Erer, Ozer Soylu, Ayşe Emre, Kemal Sayar, Mehmet Eren
OBJECTIVES: This study aimed to assess autonomic dysfunction parameters and anxiety levels in patients with mitral valve prolapse (MVP). STUDY DESIGN: We evaluated 33 patients (mean age 25+/-5 years) with MVP and 14 healthy subjects (mean age 25+/-4 years). The patients were divided into two groups according to the presence (anatomical MVP, n=11) or absence (MVP syndrome, n=22) of abnormal leaflet thickening (>5 mm). Spielberger's Situational Anxiety Scale (SSAS) and Continuous Anxiety Scale (SCAS) were administered to all the subjects, and heart rates (HR) and arterial blood pressures (BP) were measured in the supine and standing positions...
June 2009: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
Jasmine Grewal, Sunil Mankad, William K Freeman, Roger L Click, Rakesh M Suri, Martin D Abel, Jae K Oh, Patricia A Pellikka, Gillian C Nesbitt, Imran Syed, Sharon L Mulvagh, Fletcher A Miller
BACKGROUND: The aims of this study were to evaluate the feasibility of real-time 3-dimensional (3D) transesophageal echocardiography in the intraoperative assessment of mitral valve (MV) pathology and to compare this novel technique with 2-dimensional (2D) transesophageal echocardiography. METHODS: Forty-two consecutive patients undergoing MV repair for mitral regurgitation (MR) were studied prospectively. Intraoperative 2D and 3D transesophageal echocardiographic (TEE) examinations were performed using a recently introduced TEE probe that provides real-time 3D imaging...
January 2009: Journal of the American Society of Echocardiography
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