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https://www.readbyqxmd.com/read/29236217/the-association-between-medical-diagnosis-and-caregiver-burden-a-cross-sectional-study-of-recipients-of-informal-support-and-caregivers-from-the-general-population-study-good-aging-in-sk%C3%A3-ne-sweden
#1
Sölve Elmståhl, Beth Dahlrup, Henrik Ekström, Eva Nordell
BACKGROUND: Different kinds of chronic diseases might imply different dimensions of caregiver burden, not previously described among the caregivers to recipients from the general elder population. AIM: The main objective was to examine differences in burden between the 343 caregivers to persons with different diagnoses. METHODS: A group of elderly recipients of informal care (n = 343) from the general population study 'Good Aging in Skåne' (GÅS) Sweden, were divided into five diagnostic groups: dementia (n = 90), heart and lung diseases (n = 48), stroke (n = 62), fractures (n = 66), depression (n = 40) and the group "other", consisting of different diagnoses (n = 37) according to ICD-10...
December 13, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29235986/managing-diabetes-in-people-with-dementia-a-realist-review
#2
Frances Bunn, Claire Goodman, Peter Reece Jones, Bridget Russell, Daksha Trivedi, Alan Sinclair, Antony Bayer, Greta Rait, Jo Rycroft-Malone, Chris Burton
BACKGROUND: Dementia and diabetes mellitus are common long-term conditions that coexist in a large number of older people. People living with dementia and diabetes may be at increased risk of complications such as hypoglycaemic episodes because they are less able to manage their diabetes. OBJECTIVES: To identify the key features or mechanisms of programmes that aim to improve the management of diabetes in people with dementia and to identify areas needing further research...
December 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29235927/risk-factors-for-hospital-death-in-conditions-needing-palliative-care-nationwide-population-based-death-certificate-study
#3
Barbara Gomes, Maria João Pinheiro, Sílvia Lopes, Maja de Brito, Vera P Sarmento, Pedro Lopes Ferreira, Henrique Barros
BACKGROUND: Most people would prefer to die at home as opposed to hospital; therefore, understanding mortality patterns by place of death is essential for health resources allocation. AIM: We examined trends and risk factors for hospital death in conditions needing palliative care in a country without integrated palliative care. DESIGN: This is a death certificate study. We examined factors associated with hospital death using logistic regression...
November 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/29235658/baseline-characteristics-and-outcomes-of-older-adults-seeking-care-in-ambulatory-urgent-care-clinics
#4
Bernardo J Reyes, Javier M Lopez, Diana J Galindo, Maria Briceno, Joseph G Ouslander
OBJECTIVES: To determine the most common clinical conditions associated with older adults visiting Urgent care centers (UCCs) and the potential need for further resource use. DESIGN: Cross-sectional retrospective study. SETTING: Nonprofit academic medical center with campuses and multiple satellite offices in Ohio and Florida. PARTICIPANTS: Individuals aged 55 and older who visited UCCs between August 2014 and March 2015 (N = 9,445; average age 63...
December 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29235616/-social-cognition-in-parkinson-s-disease-dementia-and-behavioral-variant-of-frontotemporal-dementia
#5
M E Tabernero, F Musich, F C Cossini, D G Politis
AIM: To study the presence of alterations in social cognition in Parkinson's disease dementia (PDD) and behavioral variant frontotemporal dementia (bvFTD), to compare the levels of involvement, and to analyze their relevance as a tool to distinguish between both demential profile. SUBJECTS AND METHODS: For this purpose, 34 patients diagnosed with PDD, 21 men and 13 women, with an average age of 70 years and 8 years of education, and 26 patients diagnosed with bvFTD, 9 men and 17 women, with an average age of 68 years and 6 years of education, were assessed...
December 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/29235432/impact-of-informal-caregiving-on-cognitive-function-and-well-being-in-canada
#6
Sasha Mallya, Alexandra J Fiocco
BACKGROUND: With a rise in the aging population and a consequential rise in persons diagnosed with dementia comes an increase in the number of informal caregivers who are caring for a loved one. The objective of the proposed study was to assess the neurocognitive and psychological effects of caring for a person with dementia or a related neurodegenerative disease in a sample of Canadian informal caregivers. METHODS: Fifty-seven informal caregivers of a person with dementia or a related neurodegenerative disease (mean age = 66...
December 13, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29235430/prevalence-and-risk-factors-for-delirium-diagnosis-in-patients-followed-in-general-practices-in-germany
#7
Jens Bohlken, Karel Kostev
BACKGROUND: The aim of this study is to identify the prevalence and risk factors of documented delirium in general practices in Germany. METHODS: The present study includes 2,194 patients over the age of 65 years with delirium and 2,194 controls without delirium from a sample of 6,180,042 patients from 1,262 general practices. Multivariate logistic regression models were fitted with delirium as a dependent variable and other disorders and drugs as potential predictors...
December 13, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29235429/evolution-and-future-directions-for-the-concept-of-mild-cognitive-impairment
#8
Stina Saunders, Karen Ritchie, Tom C Russ, Graciela Muniz-Terrera, Craig W Ritchie
The term mild cognitive impairment has been associated with a varying degree of clinical utility and controversy. The concept has been introduced to try and define a pre-dementia period associated with underlying neurodegenerative pathology and a higher likelihood of the person developing a dementia syndrome. As scientific understanding improves then the definition of MCI rightly adapts, meaning that the MCI concept is prone quite rightly to frequent evolution. We consider that we are a long way away from the concept having evolved to a point where it can be embedded with confidence in clinical practice as a diagnosis but should remain as a term primarily for use in research...
December 13, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29235398/antipsychotic-treatment-of-community-dwelling-and-institutionalised-patients-with-dementia-in-germany
#9
Philipp Hessmann, Richard Dodel, Erika Baum, Matthias J Müller, Greta Paschke, Bernhard Kis, Jan Zeidler, Mike Klora, Jens-Peter Reese, Monika Balzer-Geldsetzer
OBJECTIVE: A restrictive use of antipsychotic drugs in patients with Alzheimer's disease (AD) is recommended due to an increased risk of cerebrovascular events and mortality. We hypothesise that the prescription of antipsychotics is associated with the patients' socio-demographic and clinical status (e.g., dementia severity). METHODS: The prescription of antipsychotics was cross-sectionally evaluated in 272 community-dwelling and 123 institutionalised patients with AD across all severity stages of dementia...
December 13, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/29235393/needs-of-people-with-advanced-dementia-in-their-final-phase-of-life-a-multi-perspective-qualitative-study-in-nursing-homes
#10
Holger Schmidt, Yvonne Eisenmann, Heidrun Golla, Raymond Voltz, Klaus Maria Perrar
BACKGROUND: People with advanced dementia present an important target group for palliative care. They suffer a range of symptoms, and their verbal communication abilities are highly restricted. At present, little is known about their needs in the final phase of life. AIM: To identify the needs of people with advanced dementia in their final phase of life and to explore the aspects relevant to first recognize and then meet these needs. DESIGN: Multi-perspective qualitative study using grounded theory methodology conducting group discussions, individual interviews, and participant observation...
December 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/29235386/how-is-palliative-care-understood-in-the-context-of-dementia-results-from-a-massive-open-online-course
#11
Fran McInerney, Kathleen Doherty, Aidan Bindoff, Andrew Robinson, James Vickers
BACKGROUND: A palliative approach to the care of people with dementia has been advocated, albeit from an emergent evidence base. The person-centred philosophy of palliative care resonates with the often lengthy trajectory and heavy symptom burden of this terminal condition. AIM: To explore participants' understanding of the concept of palliative care in the context of dementia. The participant population took an online course in dementia. DESIGN: The participant population took a massive open online course on 'Understanding Dementia' and posted answers to the question: 'palliative care means …' We extracted these postings and analysed them via the dual methods of topic modelling analysis and thematic analysis...
November 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/29235275/-identification-and-function-analysis-of-neuroprotective-targets-group-of-modified-wuzi-yanzong-pill
#12
Ke-Wu Zeng, Yan-Jun Wan, Li-Xi Liao, Kun Jiang, Xue-Mei Wang, Lian-Ying Liu, Peng-Fei Tu
Targets group identification in complex Chinese medicine system is a key step for revealing the potential mechanism of Chinese medicine. The solid beads with magnetic core and benzophenone-modified surface were made in our study, and then benzophenone was activated and cross-linked with the C-H bonds of chemical compositions in Chinese medicines under UV excitation. Thus the chemical compositions of modified Wuzi Yanzong pill(MWP) were linked to the solid bead surface, and enriched the neuroprotective targets group of MWP after being co-incubated with nerve cell lysate...
October 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29235073/-quality-of-life-of-nursing-home-residents-with-dementia-before-during-and-after-playing-with-a%C3%A2-magic-table
#13
Leonie Bruil, Marian J M Adriaansen, Judith W M Groothuis, Ercolie R Bossema
The 'Active Cues Magic Table' is a new game concept within nursing home care. It consists of light animations projected on a dining table and responding to movements of the players. The aim of this exploratory, quasi-experimental study was to examine the quality of life of nursing home residents with moderately severe or severe dementia before, during and after playing with this magic table. Quality of life was assessed with the Qualidem and the DS-DAT. Of the 34 nursing home residents included, 62% were female and mean age was 86...
December 12, 2017: Tijdschrift Voor Gerontologie en Geriatrie
https://www.readbyqxmd.com/read/29234918/patients-with-dementia-in-acute-care-hospitals-a%C3%A2-cross-sectional-study-of-physicians-experiences-and-attitudes
#14
Lena Helm, Katrin Balzer, Anja Behncke, Nora Eisemann, Sascha Köpke
BACKGROUND: Patients with dementia (PwD) are a vulnerable group and caring for these patients in acute care hospitals is challenging. Structural conditions and standardized treatment procedures in hospitals often do not correspond to the needs of this patient group. Physicians may not be well prepared for caring for PwD. OBJECTIVE: This study aimed to ascertain physicians' experiences and attitudes in caring for PwD or cognitive disorders and their subjective workload...
December 12, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/29234900/trace-lithium-and-mental-health
#15
REVIEW
Nobuyoshi Ishii, Takeshi Terao
Lithium therapy is generally accepted as a first-line treatment for bipolar disorder, and it is also identified as one of the best augmenting options for treatment-resistant depression. Furthermore, lithium has been investigated in association with suicide, dementia and aggressiveness. In this review, we examined articles about the effects of very small amounts of lithium in treating suicide, dementia, bipolar disorder and temperament, to assess the present state of trace lithium's effect on mental state. The results indicate that trace lithium may be effective for suicide prevention but randomized, placebo-controlled trials are required to draw a definite conclusion...
December 12, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29234814/hormone-therapy-for-the-primary-prevention-of-chronic-conditions-in-postmenopausal-women-us-preventive-services-task-force-recommendation-statement
#16
David C Grossman, Susan J Curry, Douglas K Owens, Michael J Barry, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Ann E Kurth, C Seth Landefeld, Carol M Mangione, Maureen G Phipps, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: Menopause occurs at a median age of 51.3 years, and the average US woman who reaches menopause is expected to live another 30 years. The prevalence and incidence of most chronic conditions, such as coronary heart disease, dementia, stroke, fractures, and breast cancer, increase with age; however, the excess risk for these conditions that can be attributed to menopause alone is uncertain. Since the publication of findings from the Women's Health Initiative that hormone therapy use is associated with serious adverse health effects in postmenopausal women, use of menopausal hormone therapy has declined...
December 12, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29234813/hormone-therapy-for-the-primary-prevention-of-chronic-conditions-in-postmenopausal-women-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#17
Gerald Gartlehner, Sheila V Patel, Cynthia Feltner, Rachel Palmieri Weber, Rachel Long, Kelly Mullican, Erin Boland, Linda Lux, Meera Viswanathan
Importance: Postmenopausal status coincides with increased risks for chronic conditions such as heart disease, osteoporosis, cognitive impairment, or some types of cancers. Previously, hormone therapy was used for the primary prevention of these chronic conditions. Objective: To update evidence for the US Preventive Services Task Force on the benefits and harms of hormone therapy in reducing risks for chronic conditions. Data Sources: MEDLINE, Cochrane Library, EMBASE, and trial registries from June 1, 2011, through August 1, 2016...
December 12, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29234725/computerized-cognitive-training-for-older-diabetic-adults-at-risk-of-dementia-study-protocol-for-a-randomized-controlled-trial
#18
Rachel Bloom, Michal Schnaider-Beeri, Ramit Ravona-Springer, Anthony Heymann, Hai Dabush, Lior Bar, Shirel Slater, Yuri Rassovsky, Alex Bahar-Fuchs
Introduction: Older adults with type 2 diabetes are at high risk of cognitive decline and dementia and form an important target group for dementia risk reduction studies. Despite evidence that computerized cognitive training (CCT) may benefit cognitive performance in cognitively healthy older adults and those with mild cognitive impairment, whether CCT may benefit cognitive performance or improve disease self-management in older diabetic adults has not been studied to date. In addition, whether adaptive difficulty levels and tailoring of interventions to individuals' cognitive profile are superior to generic training remains to be established...
November 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29234724/lower-cerebral-blood-flow-in-subjects-with-alzheimer-s-dementia-mild-cognitive-impairment-and-subjective-cognitive-decline-using-two-dimensional-phase-contrast-magnetic-resonance-imaging
#19
Jolien F Leijenaar, Ingrid S van Maurik, Joost P A Kuijer, Wiesje M van der Flier, Philip Scheltens, Frederik Barkhof, Niels D Prins
Introduction: In this cross-sectional study, we aimed to detect differences in cerebral blood flow (CBF) between subjects with Alzheimer's disease (AD), mild cognitive impairment (MCI), and subjective cognitive decline (SCD), using two-dimensional phase-contrast magnetic resonance imaging. Methods: We included 74 AD patients (67 years, 51% female), 36 MCI patients (66 years, 33% female), and 62 patients with SCD (60 years, 32% female) from the Amsterdam Dementia Cohort...
2017: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/29234406/amelioration-of-scopolamine-induced-learning-and-memory-impairment-by-%C3%AE-pinene-in-c57bl-6-mice
#20
Gil-Yong Lee, Chan Lee, Gyu Hwan Park, Jung-Hee Jang
Increasing evidence suggests that neurodegenerative disorders such as Alzheimer's disease (AD) are mediated via disruption of cholinergic neurons and enhanced oxidative stress. Therefore, attention has been focused on searching for antioxidant phytochemicals for the prevention and/or treatment of AD through their ability to fortify cholinergic function and antioxidant defense capacity. In this study, we have investigated the neuroprotective effect of α-pinene (APN) against learning and memory impairment induced by scopolamine (SCO, 1 mg/kg, i...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
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