Yuki Kimoto, Satoru Oshino, Naoki Tani, Koichi Hosomi, Hui Ming Khoo, Yuya Fujita, Shimpei Miura, Takamitsu Iwata, Takuto Emura, Takahiro Matsuhashi, Yuji Onoda, Takamasa Ishiuchi, Takufumi Yanagisawa, Masayuki Hirata, Haruhiko Kishima
Intrathecal baclofen (ITB) therapy effectively treats spasticity caused by brain or spinal cord lesions. However, only a few studies compare the course of treatment for different diseases. We investigated the change in daily dose of baclofen per year and its associated adverse events in patients presenting with the three most common etiologies at our institute: hereditary spastic paraplegia, cerebral palsy, and spinal cord injury. The ITB pumps were implanted from July 2007 to August 2019, with a mean follow-up period of 70 months...
December 15, 2023: Neurologia Medico-chirurgica