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Intrathecal baclofen

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https://www.readbyqxmd.com/read/27903018/intrathecal-baclofen-therapy-for-the-treatment-of-spasticity-in-lithuania
#1
Robertas Kvascevicius, Ona Lapteva, Jurate Kesiene, Alfredas Vaitkus, Laima Mikulenaite, Ramunas Raugalas, Jurate Sipylaite, Saulius Rocka, Alvydas Juocevicius
Spasticity of cerebral or spinal origin severely impairs an individual's functional ability and quality of life. Intrathecal baclofen (ITB) therapy via an implantable pump is indicated for use in patients unresponsive to oral antispasmodics. ITB therapy improves the daily caring for and relief of painful spasms. In Lithuania, ITB therapy was introduced in clinical practice just recently. We share our experience of spasticity management with the ITB pump system in five patients at Vilnius University Hospital Santariskiu Klinikos...
November 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27885944/letter-to-the-editor-ascenda-catheter-versus-silicone-catheter-in-intrathecal-baclofen-therapy
#2
Nathalie Draulans, Tom Theys, Bart Nuttin, Carlotte Kiekens
No abstract text is available yet for this article.
November 25, 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27851494/1859-administration-of-intrathecal-baclofen-via-lumbar-drain-to-prevent-withdrawal
#3
Elizabeth Leung, Christopher Leong, Deepika Pereira, Kasey Greathouse, Gavin Gardner
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851443/1808-intrathecal-baclofen-via-external-temporary-catheter-and-syringe-pump-a-case-series
#4
Sarah Adriance, Kristin Brower, Albert Clairmont
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27767242/solubility-and-stability-of-baclofen-3-mg-ml-intrathecal-formulation-and-its-compatibility-with-implantable-programmable-intrathecal-infusion-systems
#5
Baohua Yue, Ron Brendel, Amelia Lukitsch, Thomas Prentice, Brian Doty
BACKGROUND: Commercial baclofen formulations used with infusion pumps are available at therapeutic concentrations of 0.5-2.0 mg/mL. However, patients who receive higher daily doses of baclofen may benefit from products with greater baclofen concentrations since their refill frequency would be reduced (up to a maximum of 180 days). We evaluated baclofen solubility, baclofen 3 mg/mL intrathecal (IT) formulation stability, and chemical and physical compatibility with Medtronic SynchroMed(®) II and Codman Medstream(®) programmable IT infusion pumps...
October 21, 2016: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/27682809/intrathecal-baclofen-withdrawal-a-rare-cause-of-reversible-cardiomyopathy
#6
Stephen O Awuor, Paul M Kitei, Yassir Nawaz, Amy M Ahnert
Baclofen is commonly used to treat spasticity of central etiology. Unfortunately, a potentially lethal withdrawal syndrome can complicate its use. This is especially true when the drug is administered intrathecally. There are very few cases of baclofen withdrawal leading to reversible cardiomyopathy described in the literature. The authors present a patient with a history of chronic intrathecal baclofen use who, in the setting of acute baclofen withdrawal, develops laboratory, electrocardiogram, and echocardiogram abnormalities consistent with cardiomyopathy...
September 28, 2016: Acute Cardiac Care
https://www.readbyqxmd.com/read/27676935/perceived-effectiveness-tolerance-of-cares-in-children-and-adults-with-cerebral-palsy
#7
Laetitia Houx, Hélène Saudreau, Philippe Galien, Christelle Pons, Marion Roquet, Ronan Garlantezec, Sylvain Brochard
OBJECTIVE: A better understanding of the perception of the rehabilitative and medical care's by persons with cerebral palsy (CP) and their families may help in providing better adherence to these cares. The main objective of this study was to assess overall satisfaction, self-perception of effectiveness and tolerance of the rehabilitative and medical cares in individuals with CP. MATERIAL AND METHODS: This was a cross-sectional questionnaire-based study. A total of 950 questionnaires were sent to French Britain children and adults with CP...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676793/assessment-of-intrathecal-baclofen-pump-malfunction-a-new-algorithm-including-nuclear-medicine-investigation
#8
Flavie Frémondière, Franck Lacoeuille, Avigaëlle Sher, Olivier Couturier, Philippe Menei, Isabelle Richard, Mickaël Dinomais
Intrathecal baclofen is now an admitted treatment of generalized and disabling spasticity. Technical incidents of the device remain frequent, mainly due to catheter problems. Consequences can be abrupt with life-threatening withdrawal syndrome or progressive with spasticity reappearance. In case of progressive withdrawal syndrome, the assessment process has to be meticulous to find the cause of inefficiency and to avoid useless revision surgery. This assessment includes medical examination, radiographs, intrathecal baclofen bolus, after what, if no conclusion can be drawn, a more invasive imaging exam has to be performed...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27673125/poster-373-paradoxically-increased-rigidity-after-intrathecal-baclofen-injection-in-a-patient-with-multiple-sclerosis-a-case-report
#9
Diana L Marchese
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673124/poster-372-long-term-intrathecal-baclofen-treatment-for-spasticity-after-acquired-brain-injury-does-diagnosis-affect-dosing
#10
Mithra B Maneyapanda, Zachary McCormick, Christina M Marciniak, Christopher D Reger
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673103/poster-352-management-of-acute-baclofen-withdrawal-in-the-setting-of-intrathecal-pump-infection-a-case-report
#11
Neil V Mandalaywala, Young Il Seo, Heidi N Fusco
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673050/poster-291-improved-upper-extremity-spasticity-during-continuous-intrathecal-baclofen-trial-with-high-cervical-catheter-placement-a-case-report
#12
Melissa Roscher, Michael C Munin
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673034/poster-277-maternal-intrathecal-baclofen-therapy-conveys-no-added-risk-to-the-child-during-years-0-3-a-case-report
#13
Reza Farid, Liz Barton
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27673007/poster-248-a-novel-infusion-method-of-intrathecal-baclofen-using-personal-therapy-manager-a-case-series
#14
Armen Derian, Seema Khurana, Brianna L Hoffmann, Charles A Plumlee
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27672968/poster-207-malpositioned-intrathecal-baclofen-pump-catheter-penetrating-the-colon-a-case-report
#15
Samantha A Benjamin, Henry S York
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27642571/intrathecal-baclofen-pump-migration-into-the-peritoneal-cavity-a-case-report
#16
Timothy J Kovanda, Ecaterina Pestereva, Albert Lee
INTRODUCTION: Intrathecal baclofen pumps are valuable treatment options for those with cerebral palsy. Although subfascial baclofen pump placement is generally preferred over a subcutaneous pump placement due to lower infection rates, rare complications can occur with the subfascial approach such as pump migration. CASE PRESENTATION: The authors here describe a case of baclofen pump migration into the peritoneal cavity of a 26-year-old male patient with cerebral palsy, shunted hydrocephalus, and epilepsy...
June 2016: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/27602250/intrathecal-baclofen-therapy-for-spasticity-a-compliance-based-study-to-indicate-effectiveness
#17
Hussam Abou Al-Shaar, Ahmed Alkhani
BACKGROUND: Intrathecal baclofen (ITB) therapy using a programmable battery-based pump is a well-recognized option in the treatment of patients with refractory spasticity. Improvements in clinical scale scores for muscle spasticity among this heterogeneous group of patients may not reflect the functional benefits of this therapeutic option. The aim of our study is to report the efficacy of ITB therapy by setting the patient's compliance at the 2-year follow-up after pump implantation as an indicator of treatment efficacy, as appreciated by the patients or their caregivers...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27579582/assessing-and-treating-pain-in-movement-disorders-amyotrophic-lateral-sclerosis-severe-acquired-brain-injury-disorders-of-consciousness-dementia-oncology-and-neuroinfectivology-evidence-and-recommendations-from-the-italian-consensus-conference-on-pain-in-neurorehabilitation
#18
Michelangelo Bartolo, Adriano CHIò, Sergio Ferrari, Cristina Tassorelli, Stefano Tamburin, Micol Avenali, Eva Azicnuda, Andrea Calvo, Augusto T Caraceni, Giovanni Defazio, Roberto DE Icco, Rita Formisano, Simone Franzoni, Elena Greco, Iwona Jedrychowska, Francesca Magrinelli, Umberto Manera, Enrico Marchioni, Sara Mariotto, Salvatore Monaco, Andrea Pace, Donatella Saviola, Isabella Springhetti, Michele Tinazzi, Antonio DE Tanti
BACKGROUND: Pain is an important non-motor symptom in several neurological diseases, such as Parkinson's disease, cervical dystonia, amyotrophic lateral sclerosis, severe acquired brain injury, disorders of consciousness and dementia, as well as in oncology and neuroinfectivology. AIMS: To overcome the lack of evidence-based data on pain management in these diseases, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) defined criteria for good clinical practice among Italian neurorehabilitation professionals...
August 31, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27543991/does-every-patient-require-an-intrathecal-baclofen-trial-before-pump-placement
#19
EDITORIAL
Gerald S Bilsky, Michael Saulino, Michael W O'Dell
No abstract text is available yet for this article.
August 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27477589/can-cerebrospinal-fluid-pressure-detect-catheter-complications-in-patients-who-experience-loss-of-effectiveness-with-intrathecal-baclofen-therapy
#20
Michael Saulino, Michael Turner, Keith Miesel, Felicia R Cochran, Katherine Stromberg, Elizabeth Fehrmann, Mary Markert, Robert Spencer
OBJECTIVE: The catheter status of patients who presented with loss of intrathecal baclofen (ITB) therapy effectiveness was investigated using measurements of cerebrospinal fluid (CSF) pressure transmitted through the catheter fluid path to the pump. The aim of the study was to estimate the appropriate threshold separating catheter complications from "normal" catheter function, and to compare catheter status based on CSF pressure with the clinical diagnosis. METHODS: This was a prospective, masked nonsignificant risk, research study...
August 1, 2016: Neuromodulation: Journal of the International Neuromodulation Society
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