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https://www.readbyqxmd.com/read/29649090/reliability-of-rod-lengthening-thoracic-and-spino-pelvic-measurements-on-biplanar-stereoradiography-in-patients-treated-with-magnetically-controlled-growing-rods
#1
Peter Obid, Karen Kar Lum Yiu, Kenneth Mc Cheung, Kenny Kwan, Michael Ruf, Jason Pui Yin Cheung
STUDY DESIGN: Cross-sectional study. OBJECTIVE: To assess the inter- and intraobserver reliability of thoracic, spino-pelvic and rod lengthening measurements made on biplanar spinal stereoradiography (EOS imaging) in children treated with magnetically controlled growing rod (MCGR). SUMMARY OF BACKGROUND DATA: MCGR treatment aims to gain spine length while gradually correcting the spinal deformity. Monitoring thoracic and spino-pelvic parameters are crucial for successful management...
April 11, 2018: Spine
https://www.readbyqxmd.com/read/29644031/the-use-of-magnetically-controlled-growing-rods-in-paediatric-osteogenesis-imperfecta-with-early-onset-progressive-scoliosis
#2
A Gardner, J Sahota, H Dong, V Saraff, W Högler, N J Shaw
Osteogenesis Imperfecta (OI) is a condition of bone fragility and can present with early onset scoliosis that can cause respiratory complications in later life. The fear of instrumenting the spine in OI is the possibility of fracture either on primary insertion or subsequent lengthening. Magnetically controlled growing rods were inserted to control a scoliosis in a 6-year old with OI type IV. Fixation was obtained using pedicle screws proximally and distally with sublaminar bands around the ribs proximally...
March 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29629587/an-nihr-approved-two-year-observational-study-on-magnetically-controlled-growth-rods-in-the-treatment-of-early-onset-scoliosis
#3
C Nnadi, C Thakar, J Wilson-MacDonald, P Milner, A Rao, D Mayers, J Fairbank, T Subramanian
Aims The primary aim of this study was to evaluate the performance and safety of magnetically controlled growth rods in the treatment of early onset scoliosis. Secondary aims were to evaluate the clinical outcome, the rate of further surgery, the rate of complications, and the durability of correction. Patients and Methods We undertook an observational prospective cohort study of children with early onset scoliosis, who were recruited over a one-year period and followed up for a minimum of two years. Magnetically controlled rods were introduced in a standardized manner with distractions performed three-monthly thereafter...
April 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29622758/lumbar-spine-bone-mineral-density-z-score-discrepancies-by-dual-x-ray-absorptiometry-do-not-predict-vertebral-fractures-in-children
#4
Tasma Harindhanavudhi, Anna Petryk, Richard Jones, Amanda R Wallin, James S Hodges, Sara Van Nortwick, Bradley S Miller, Tara L Holm, Kyriakie Sarafoglou
Dual X-ray absorptiometry (DXA) remains the most common mode of bone mineral density (BMD) evaluation. In adults, presence of a lumbar spine (LS) BMD T-score discrepancy (>1 SD difference between adjacent vertebrae) can indicate a vertebral fracture. In children, however, the clinical significance of such discrepancies is unknown. We conducted a retrospective study to evaluate the association between LS DXA and LS morphology to elucidate the clinical significance of an LS BMD Z-score discrepancy. We identified 360 DXA scans performed between September 2014 and May 2016 in patients 5-18 years of age...
April 4, 2018: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/29619522/solitary-fibrous-tumour-of-the-spine-imaging-features-of-a-commonly-misdiagnosed-entity
#5
Ning Lang, Enlong Zhang, Xiaoying Xing, Huishu Yuan
OBJECTIVE: Solitary fibrous tumours (SFTs) occurring in the spine are rare. Herein, we review the clinical and imaging data of spinal SFT. METHODS: We retrospectively analysed eight cases of pathologically confirmed spinal SFT imaging and clinical data, pathological manifestations, surgical methods, and follow-up results. RESULTS: Five SFTs cases occurred in the cervical spine, two in the thoracic spine, and one in the lumbosacral spine. Five cases showed a dumbbell-shaped or lobulated soft tissue mass that grew across the intervertebral foramen, two cases showed an expansive intraosseous mass formation in the vertebral body and/or posterior element, and one case showed a long-spindle shaped intraspinal canal mass growing along the spinal canal...
April 4, 2018: European Radiology
https://www.readbyqxmd.com/read/29558021/trunk-rotation-due-to-persistence-of-primitive-reflexes-in-early-school-age-children
#6
Ewa Z Gieysztor, Ludwika Sadowska, Anna M Choińska, Małgorzata Paprocka-Borowicz
BACKGROUND: The angle of trunk rotation (ATR) is a measurement that allows an objective assessment of a growing child's spine. Early detection of trunk rotation prevents the progression of scoliosis. One of the factors that predispose children to the formation of faulty posture may be primitive reflexes, which should be integrated in the central nervous system (CNS) by the age of one year. If retained, primitive reflexes affect children's physical development as well as their development at school...
March 14, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29557873/prophylactic-intrawound-vancomycin-powder-a-fait-accompli-commentary-on-an-article-by-george-h-thompson-md-et-al-does-vancomycin-powder-decrease-surgical-site-infections-in-growing-spine-surgery-a-preliminary-study
#7
Matthew L Webb, Robert M Campbell
No abstract text is available yet for this article.
March 21, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29557862/does-vancomycin-powder-decrease-surgical-site-infections-in-growing-spine-surgery-a-preliminary-study
#8
George H Thompson, Connie Poe-Kochert, Christina K Hardesty, Jochen Son-Hing, R Justin Mistovich
BACKGROUND: Vancomycin powder has been demonstrated to be safe in children, and yet there are no data on its use to reduce surgical site infections (SSIs) in surgery for early-onset scoliosis. METHODS: We performed a retrospective study of our patients treated for early-onset scoliosis in the period of 2010 to 2016. In 2010, we updated our standardized perioperative growing spine care path. The only later change was the gradual introduction of intrawound vancomycin powder...
March 21, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29556745/giant-cell-tumor-of-the-rib-cage-extending-to-the-spine-case-report
#9
Juan Francisco Blanco, Marcelo Jiménez, Diego Rendón, David Pescador, Jorge Hugo Villafañe, Diego Garbossa, Pedro Berjano
PURPOSE: We present the case of a patient with a giant cell tumor of the thoracic wall that invaded the thoracic spine. MATERIAL AND METHODS: A giant cell tumor that affects the spine and the thoracic wall is very rare but can grow to a large size. We report a case of giant cell tumor of the left chest wall extending to the thoracic spine in a 28-year-old man. Positron emission tomography (PET) showed a tumor of 11 × 4 × 13 cm in size and the histopathology specimen of the first surgical procedure diagnosed a giant cell tumor...
March 19, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29540432/impact-of-body-weight-loss-from-maximum-weight-on-fragility-bone-fractures-in-japanese-patients-with-type-2-diabetes-the-fukuoka-diabetes-registry
#10
Yuji Komorita, Masanori Iwase, Hiroki Fujii, Toshiaki Ohkuma, Hitoshi Ide, Tamaki Jodai-Kitamura, Akiko Sumi, Masahito Yoshinari, Udai Nakamura, Dongchon Kang, Takanari Kitazono
OBJECTIVE: There is growing evidence that weight loss is associated with increased fracture risk in the general population. As patients with diabetes often lose weight intentionally or unintentionally, we aimed to investigate prospectively the relationship between weight loss from maximum body weight and fracture risk. RESEARCH DESIGN AND METHODS: A total of 4,706 Japanese participants with type 2 diabetes (mean age 66 years), including 2,755 men and 1,951 postmenopausal women, were followed for a median of 5...
March 14, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29534415/-outcome-of-traditional-growing-rods-for-correction-of-apical-vertebra-rotation-in-early-onset-scoliosis
#11
X Sun, L Xu, Z H Chen, X Chen, C Z Du, S Li, Z Liu, B P Qian, B Wang, Z Z Zhu, Y Qiu
Objective: To evaluate the correction result of traditional dual growing rods on apical vertebral rotation. Methods: This study recruited 19 early-onset scoliosis patients (6 boys and 13 girls) who had received traditional dual growing rods treatment at Department of Spine Surgery, Nanjing Drum Tower Hospital from January 2009 to July 2015. The age at initial surgery was (5.7±1.7)years(range, 3 to 9 years). Measurements of primary curve magnitude, height of T(1)-S(1), apical vertebral translation(AVR), apical vertebral body-rib ratio, apical vertebral rotation, thoracic rotation and rib hump were compared between pre-operatively, post-operatively, and at latest follow-up, through a paired- t test...
March 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29503098/the-tetrapartite-synapse-a-key-concept-in-the-pathophysiology-of-schizophrenia
#12
Gabriele Chelini, Harry Pantazopoulos, Peter Durning, Sabina Berretta
Growing evidence points to synaptic pathology as a core component of the pathophysiology of schizophrenia (SZ). Significant reductions of dendritic spine density and altered expression of their structural and molecular components have been reported in several brain regions, suggesting a deficit of synaptic plasticity. Regulation of synaptic plasticity is a complex process, one that requires not only interactions between pre- and post-synaptic terminals, but also glial cells and the extracellular matrix (ECM)...
March 1, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29484249/the-utilization-of-mulligan-concept-thoracic-sustained-natural-apophyseal-glides-on-patients-classified-with-secondary-impingement-syndrome-a-multi-site-case-series
#13
Dawn P Andrews, Kari B Odland-Wolf, James May, Russell Baker, Alan Nasypany
Background and Purpose: Secondary impingement syndrome (SIS) is a common complaint in the sporting population particularly among athletes engaging in overhead activities. While symptoms may be present at the shoulder with patients complaining of SIS, spinal alignment or dysfunction can influence scapular positioning and overall shoulder girdle function. As an adjunct therapy to traditional interventions for SIS, thoracic high-velocity low-amplitude (HVLA) thrusts have been utilized and correlated with patient reported decreases in pain...
February 2018: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/29480409/the-global-spine-care-initiative-a-summary-of-the-global-burden-of-low-back-and-neck-pain-studies
#14
REVIEW
Eric L Hurwitz, Kristi Randhawa, Hainan Yu, Pierre Côté, Scott Haldeman
PURPOSE: This article summarizes relevant findings related to low back and neck pain from the Global Burden of Disease (GBD) reports for the purpose of informing the Global Spine Care Initiative. METHODS: We reviewed and summarized back and neck pain burden data from two studies that were published in Lancet in 2016, namely: "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015" and "Global, regional, and national disability-adjusted life years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015...
February 26, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29471053/morphological-and-functional-evidence-of-increased-excitatory-signaling-in-the-prelimbic-cortex-during-ethanol-withdrawal
#15
Florence P Varodayan, Harpreet Sidhu, Max Kreifeldt, Marisa Roberto, Candice Contet
Excessive alcohol consumption in humans induces deficits in decision making and emotional processing, which indicates a dysfunction of the prefrontal cortex (PFC). The present study aimed to determine the impact of chronic intermittent ethanol (CIE) inhalation on mouse medial PFC pyramidal neurons. Data were collected 6-8 days into withdrawal from 7 weeks of CIE exposure, a time point when mice exhibit behavioral symptoms of withdrawal. We found that spine maturity in prelimbic (PL) layer 2/3 neurons was increased, while dendritic spines in PL layer 5 neurons or infralimbic (IL) neurons were not affected...
February 19, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29465475/physical-activity-and-bone-accretion-isotemporal-modeling-and-genetic-interactions
#16
Jonathan A Mitchell, Alessandra Chesi, Shana E McCormack, Diana L Cousminer, Heidi J Kalkwarf, Joan M Lappe, Vicente Gilsanz, Sharon E Oberfield, John A Shepherd, Andrea Kelly, Struan F A Grant, Babette S Zemel
PURPOSE: To determine if replacing time spent in high and low impact physical activity (PA) predicts changes in pediatric bone mineral density (BMD) and content (BMC). METHODS: We analyzed data from the longitudinal Bone Mineral Density in Childhood Study (N=2,337 with up to 7 visits). The participants were aged 5-19 years at baseline, 51.2% were female and 80.6% were non-Black. Spine, total hip, and femoral neck areal BMD (aBMD) and total body less head (TBLH) BMC Z-scores were calculated...
February 20, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29464369/bibliometric-study-of-the-orthopaedic-publications-from-china
#17
REVIEW
Jing Sun, Yan Guo, Marius M Scarlat, Guang Lv, Xiong-Gang Yang, Yong-Cheng Hu
PURPOSE: We aimed to investigate the status quo of orthopaedic publications from China and characterize the most-cited articles to provide valuable insights for orthopaedists. METHODS: PubMed and Embase databases were used to search for Chinese orthopaedic publications from 1997 to 2017 to determine the growing pattern of Chinese research globally. Then Web of Science database was searched for articles with most citations in all journals included in the Journal Citation Report 2016 under the category of "orthopaedics" for the last five years, and the total numbers of articles in the last three respective years were also analyzed...
February 20, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29410774/peritraumatic-distress-fully-mediates-the-relationship-between-posttraumatic-stress-symptoms-preoperative-and-three-months-postoperative-in-patients-undergoing-spine-surgery
#18
Ehab Shiban, Jens Lehmberg, Ute Hoffmann, Jeff Thiel, Thomas Probst, Margret Friedl, Andreas Mühlberger, Bernhard Meyer, Youssef Shiban
Background: Growing evidence shows the significance of illness and surgical procedures as traumatizing stressors. Risk factors are widely investigated in various settings and samples, using numerous measures of posttraumatic stress and posttraumatic stress disorder (PTSD). While pretrauma psychological distress is acknowledged as an influential factor, peritraumatic experiences are controversially still being discussed as relevant to the development of PTSD. Objective: In a group of patients consecutively undergoing elective spine surgery (N = 89) in a German hospital, this longitudinal study addressed the question of how pretrauma PTSD symptoms and peritrauma distress interact with one another in regard to the amount of posttrauma symptoms of PTSD...
2018: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29405381/intracerebroventricular-administration-of-growth-hormone-induces-morphological-changes-in-pyramidal-neurons-of-the-hippocampus-and-prefrontal-cortex-in-adult-rats
#19
Juan David Olivares Hernández, Fabio García-García, Israel Camacho-Abrego, Gonzalo Flores, Enrique Juárez-Aguilar
A growing body of evidence suggests that growth hormone (GH) affects synaptic plasticity at both the molecular and electrophysiological levels. However, unclear is whether plasticity that is stimulated by GH is associated with changes in neuron structure. The present study investigated the effect of intracerebroventricular (ICV) administration of GH on the morphology of pyramidal neurons of the CA1 region of the dorsal hippocampus and layer III of the prefrontal cortex. Male Wistar rats received daily ICV injections of GH (120 ng) for 7 days, and they were euthanized 21 days later...
February 5, 2018: Synapse
https://www.readbyqxmd.com/read/29403256/langerhans-cell-histiocytosis-as-an-unusual-cause-of-back-pain-in-a-child-a-case-report-and-review-of-literature
#20
Hemaswetha Balachandran, Latha M Sneha, Gopinath Menon, Julius Scott
Low back pain in children and adolescents are usually attributed to mechanical causes and faulty positions. Although most of them are self-limiting, physicians should be aware of the red flag signs that warrant complete evaluation to rule out malignant causes of back pain. As delay in the diagnosis of vertebral lytic lesion may have sequelae in the growing children, pain disproportionate to the signs should have low threshold levels for evaluation. We report a case of 6-year-old boy who presented with worsening back pain...
October 2017: Journal of Craniovertebral Junction and Spine
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