keyword
https://read.qxmd.com/read/38536762/the-impact-of-musculoskeletal-ill-health-on-quality-of-life-and-function-after-critical-care-a-multicentre-prospective-cohort-study
#1
JOURNAL ARTICLE
O D Gustafson, E B King, M M Schlussel, A Arnold, C Wade, P S Nicol, M J Rowland, H Dawes, M A Williams
Physical disability is a common component of post-intensive care syndrome, but the importance of musculoskeletal health in this population is currently unknown. We aimed to determine the musculoskeletal health state of intensive care unit survivors and assess its relationship with health-related quality of life; employment; and psychological and physical function. We conducted a multicentre prospective cohort study of adults admitted to intensive care for > 48 h without musculoskeletal trauma or neurological insult...
March 27, 2024: Anaesthesia
https://read.qxmd.com/read/38536699/adaptive-synaptic-scaling-in-spiking-networks-for-continual-learning-and-enhanced-robustness
#2
JOURNAL ARTICLE
Mingkun Xu, Faqiang Liu, Yifan Hu, Hongyi Li, Yuanyuan Wei, Shuai Zhong, Jing Pei, Lei Deng
Synaptic plasticity plays a critical role in the expression power of brain neural networks. Among diverse plasticity rules, synaptic scaling presents indispensable effects on homeostasis maintenance and synaptic strength regulation. In the current modeling of brain-inspired spiking neural networks (SNN), backpropagation through time is widely adopted because it can achieve high performance using a small number of time steps. Nevertheless, the synaptic scaling mechanism has not yet been well touched. In this work, we propose an experience-dependent adaptive synaptic scaling mechanism (AS-SNN) for spiking neural networks...
March 27, 2024: IEEE Transactions on Neural Networks and Learning Systems
https://read.qxmd.com/read/38536459/association-of-ever-use-of-e-cigarettes-with-health-and-lifestyle-variables-among-young-adults-a-canadian-health-measure-survey-study
#3
JOURNAL ARTICLE
Teresa To, Cornelia M Borkhoff, Chung-Wai Chow, Theo J Moraes, Robert Schwartz, Nick Vozoris, Avtar Lal, Wendy Yen, Kimball Zhang, Emilie Terebessy, Jingqin Zhu
UNLABELLED: Research suggests that vaping raises oxidative stress levels and has been implicated in poor mental health. The objective of this study is to assess cross-sectional associations between quality of life (QOL) indicators and e-cigarette (EC) use in young Canadian adults. We used data from the 2016-2017 Canadian Health Measures Survey. We compared physical activity (daily steps), physiological measurements (high-density lipoprotein for cholesterol level), self-perceived life stress, mental health, and QOL between ever-use EC users and non-users...
March 27, 2024: European Journal of Pediatrics
https://read.qxmd.com/read/38534890/associations-of-mental-health-issues-with-health-literacy-and-vaccination-readiness-against-covid-19-in-long-term-care-facilities-a-cross-sectional-analysis
#4
JOURNAL ARTICLE
Linda Sanftenberg, Maresa Gschwendner, Andreas Grass, Marietta Rottenkolber, Isabel Zöllinger, Maria Sebastiao, Thomas Kühlein, Dagmar Hindenburg, Ildikó Gágyor, Domenika Wildgruber, Anita Hausen, Christian Janke, Michael Hoelscher, Daniel Teupser, Tobias Dreischulte, Jochen Gensichen, On Behalf Of The Bacom Study Group
Vaccinations against COVID-19 are of the utmost importance in long-term care facilities. During the pandemic, mental health issues increased significantly. This cross-sectional analysis aimed to assess the associations of depression and anxiety with health literacy in people in need of care and the association of depression and burnout with vaccination readiness against COVID-19 in health care workers (HCWs). Within our cross-sectional study, people in need of care were assessed for symptoms of depression (PHQ-9), anxiety (GAD-7), and health literacy (HLS-EU-Q16)...
February 20, 2024: European journal of investigation in health, psychology and education
https://read.qxmd.com/read/38533894/long-term-intake-of-thermo-induced-oxidized-oil-results-in-anxiety-like-and-depression-like-behaviors-involvement-of-microglia-and-astrocytes
#5
JOURNAL ARTICLE
Meishan Lu, Jiachen Shi, Xue Li, Yanjun Liu, Yuanfa Liu
Frequent consumption of fried foods has been strongly associated with a higher risk of anxiety and depression, particularly among young individuals. The existing evidence has indicated that acrylamide produced from starchy foods at high temperatures can induce anxious behavior. However, there is limited research on the nerve damage caused by thermo-induced oxidized oil (TIOO). In this study, we conducted behavioral tests on mice and found that prolonged consumption of TIOO led to significant anxiety behavior and a tendency toward depression...
March 27, 2024: Food & Function
https://read.qxmd.com/read/38532902/anxiety-and-school-avoidance-in-an-8-year-old-child-with-epilepsy
#6
JOURNAL ARTICLE
Jay Salpekar, D Dilara Ertenu
Anxiety is ubiquitous in school age children. Co-occurring medical illness adds to the complexity of identifying pathologic anxiety as opposed to that of typical development such as with social interactions or academic pressures. Anxiety may also occur in the context of cognitive difficulties or inattention, both of which may be exacerbated by epilepsy or by anti-seizure medicines themselves. Treatment strategies may require patience and long-term observations to account for the typical range of stressors that may be expected with disease progression or with development through childhood...
2024: Epilepsy & behavior reports
https://read.qxmd.com/read/38532731/long-term-depressive-symptom-trajectories-and-related-baseline-characteristics-in-primary-care-patients-analysis-of-the-psicap-clinical-trial
#7
JOURNAL ARTICLE
Maider Prieto-Vila, César González-Blanch, Francisco José Estupiñá Puig, Joshua E J Buckman, Rob Saunders, Roger Muñoz-Navarro, Juan Antonio Moriana, Paloma Rodríguez-Ruiz, Sara Barrio-Martínez, María Carpallo-González, Antonio Cano-Vindel
No abstract text is available yet for this article.
March 27, 2024: European Psychiatry: the Journal of the Association of European Psychiatrists
https://read.qxmd.com/read/38532577/just-a-gut-feeling-faecal-microbiota-transplant-for-treatment-of-depression-a-mini-review
#8
REVIEW
Minna Chang, Kai Tuomas Chang, Fuju Chang
BACKGROUND: The microbiota-gut-brain axis (MGBA) allows bidirectional crosstalk between the brain and gut microbiota (GM) and is believed to contribute to regulating mood/cognition/behaviour/metabolism/health and homeostasis. Manipulation of GM through faecal microbiota transplant (FMT) is a new, exciting and promising treatment for major depressive disorder (MDD). AIMS: This mini-review examines current research into GM and FMT as a therapy for depression. METHODS: Original research articles published in Medline/Cochrane Library/PubMed/EMBASE/PsycINFO databases/National Institute of Health website Clinicaltrials...
March 26, 2024: Journal of Psychopharmacology
https://read.qxmd.com/read/38532374/12-month-follow-up-of-intensive-outpatient-treatment-for-ptsd-combining-prolonged-exposure-therapy-emdr-and-physical-activity
#9
JOURNAL ARTICLE
Julie Rendum Klaeth, Andreas Gjerde Jensen, Trude Julie Brynhildsvoll Auren, Stian Solem
BACKGROUND: Preliminary evidence shows promising treatment outcomes at short-term follow-up for intensive posttraumatic stress disorder (PTSD) treatment, but long-term follow-up studies are sparse. This study is a sequel to a previous pilot study and open trial, set out to investigate treatment outcomes at 12-month follow-up for outpatients completing an 8-day intensive treatment for PTSD. METHODS: All patients were diagnosed with PTSD and had multiple previous psychotherapy attempts (M = 3...
March 26, 2024: BMC Psychiatry
https://read.qxmd.com/read/38531240/neurodevelopmental-profile-in-children-born-to-mothers-affected-by-systemic-sclerosis
#10
JOURNAL ARTICLE
Jessica Galli, Erika Loi, Maria Grazia Lazzaroni, Anna Molinaro, Laura Andreoli, Marzia Bendoni, Liala Moschetti, Eleonora Pedretti, Lucrezia Maria Visconti, Paolo Airò, Franco Franceschini, Angela Tincani, Elisa Fazzi
BACKGROUND: Systemic sclerosis (SSc) is a chronic immune-mediated connective tissue disease that can affect women of childbearing age. The long-term outcomes of their offspring remain poorly explored. Aim of this study was to detail the neurodevelopmental profile of children born to SSc mothers. METHODS: Twenty children (mean age: 96 ± 4.32 months; 10 males) born to SSc mothers were enrolled. We collected data on clinical history, neurological examination, cognitive profile and adaptive behavior in all subjects...
March 19, 2024: Early Human Development
https://read.qxmd.com/read/38529874/-functional-hypercortisolism-in-mental-disorder-association-with-psychopathological-manifestations-and-course-of-the-disease
#11
JOURNAL ARTICLE
O A Yunilaynen, P A Baranov, E G Starostina, E G Przhiyalkovskaya, S A Zozulya, I N Ottman, I V Oleychik
The article presents a case of a long-term mental disorder in a 35-year-old woman with a persistent laboratory-confirmed increase in cortisol levels, without clinical manifestations of hypercortisolism. The first signs of mental illness appeared at the age of 14; over the past 8 years, the disease has been continuous and manifests itself in the form of a predominantly depressive state with increasing severity and complication of symptoms. Throughout all the years of the disease, active psychopharmacotherapy was carried out, combinations of antidepressants with antipsychotics and mood stabilizers were used, but no pronounced effect was achieved...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://read.qxmd.com/read/38529873/-a-clinical-case-of-the-new-onset-bipolar-affective-disorder-in-the-postcovid-period
#12
JOURNAL ARTICLE
M N Dmitriev, D O Baeva, M S Slavgorodskaya
A large number of people who have had COVID-19 have developed mental symptoms and mood disorders. Anxiety and depression prevail among affective pathology. Evidence is accumulating that the Sars-CoV-2 virus can induce mania or hypomania in people with no personal psychopathological history. Some clinical, anamnestic and paraclinical patterns of new-onset mania and hypomania have been found. In cases of severe manic symptoms, it is possible to quickly assume the occurrence of bipolar affective disorder. The predominance of depressive and anxiety syndromes in the long-term disease and the presence of vivid vegetative symptoms can mask brief and syndromally incomplete episodes of hypomania, which distorts the understanding of the disease as a bipolar disorder...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://read.qxmd.com/read/38528589/pain-trajectories-and-neuropathic-pain-symptoms-following-lung-cancer-surgery-a-prospective-cohort-study
#13
JOURNAL ARTICLE
A V Danielsen, J J Andreasen, B Dinesen, J Hansen, K K Petersen, K S Duch, J Bisgaard, C Simonsen, L Arendt-Nielsen
BACKGROUND: Persistent postsurgical pain (PPSP) after lung cancer surgery is common and current definitions are based on evaluations at a single time point after surgery. Pain intensity and symptoms may however fluctuate and change over time, and be impacted by multiple and shifting factors. Studies of postoperative recovery patterns and transition from acute to chronic pain are needed for further investigation of preventive measures and treatments to modify unfavourable recovery paths...
March 25, 2024: European Journal of Pain: EJP
https://read.qxmd.com/read/38527688/relationships-of-self-reported-opioid-use-and-misuse-and-pain-severity-with-probable-major-depression-among-participants-with-spinal-cord-injury
#14
JOURNAL ARTICLE
James S Krause, Clara E Dismuke-Greer, Nicole D DiPiro, Jillian M R Clark, Jon Laursen-Roesler
OBJECTIVES: To examine the relationships of pain intensity, opioid use, and opioid misuse with depressive symptom severity and probable major depression (PMD) among participants with spinal cord injuries (SCI), controlling for demographic, injury, and socioeconomic characteristics. STUDY DESIGN: Cohort Study SETTING: Medical University in the Southeastern United States (US). PARTICIPANTS: Participants (n = 918) were identified from one of two sources including a specialty hospital and a state-based surveillance system in the Southeastern US...
March 23, 2024: Archives of Physical Medicine and Rehabilitation
https://read.qxmd.com/read/38526313/social-isolation-and-post-weaning-environmental-enrichment-effects-on-rat-emotional-behavior-and-serotonergic-system
#15
REVIEW
Roxana Patrícia Bezerra da Silva, Isabeli Lins Pinheiro, Regina Katiuska Bezerra da Silva, Eduarda Correia Moretti, Olavo Barbosa de Oliveira Neto, Kelli Ferraz-Pereira, Lígia Cristina Monteiro Galindo
Social isolation (SI) is related to adverse neurobehavioral effects and neurochemical changes when it occurs early in development. On the other hand, environmental enrichment (EE) is associated with a reduction in anxiety-like and depression-like behavior, as well as an increase in serotonin (5-HT) levels in the prefrontal cortex and hippocampus in rodents. This study systematically reviewed the effects of SI and EE on emotional behavior and serotonergic system components in rats after weaning. Primary experimental studies that used subgroups of rats subjected to SI, EE, and normal social conditions after weaning were considered eligible...
March 25, 2024: International Journal of Developmental Neuroscience
https://read.qxmd.com/read/38525592/udp-glucose-p2y14-receptor-signaling-exacerbates-neuronal-apoptosis-after-subarachnoid-hemorrhage-in-rats
#16
JOURNAL ARTICLE
Hideki Kanamaru, Shiyi Zhu, Siyuan Dong, Yushin Takemoto, Lei Huang, Prativa Sherchan, Hidenori Suzuki, Jiping Tang, John H Zhang
BACKGROUND: Subarachnoid hemorrhage (SAH) is a severe subtype of stroke with poor outcomes. Abnormal glucose metabolism often occurs after SAH, but the strict control of blood glucose levels is not always beneficial. This study aimed to investigate the contribution of uridine diphosphate glucose (UDP-G), an intermediate of glucose/glycogen metabolism, and its receptor P2Y14 (P2Y purinoceptor 14) to SAH pathology and explored the potential targeted treatments in rats. METHODS: A total of 218 Sprague-Dawley male rats were used...
March 25, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38525445/a-difference-in-difference-analysis-of-the-south-carolina-2015-extreme-floods-and-the-association-with-maternal-health
#17
JOURNAL ARTICLE
Maggie M Sugg, Jennifer D Runkle, Sophie Ryan, Luke Wertis
Research documenting the public health impacts of natural disasters often focuses on adults and children. Little research has examined the influence of extreme events, like floods, on maternal health, and less has examined the effect of disasters on maternal indicators like severe maternal morbidity (SMM) or unexpected outcomes of labor and delivery that result in significant short-or long-term consequences to a woman's health. The aim of this study is to identify the impacts of the 2015 flood events on maternal health outcomes in South Carolina, USA...
October 15, 2023: International Journal of Disaster Risk Reduction: IJDRR
https://read.qxmd.com/read/38525260/associations-between-pregnancy-loss-and-common-mental-disorders-in-women-a-large-prospective-cohort-study
#18
JOURNAL ARTICLE
Qiaoqiao Shen, Wenfang Zhong, Xiaomeng Wang, Qi Fu, Chen Mao
BACKGROUND: Increasing evidence suggests that pregnancy loss can lead to negative emotional outcomes, such as anxiety and depression, for women. However, limited knowledge exists regarding the long-term risk of mental disorders among individuals who have experienced pregnancy loss. OBJECTIVE: To investigate the associations between pregnancy loss and the risk of common mental disorders. METHODS: In the UK Biobank, a total of 218,990 women without any mental disorder at baseline were enrolled between 2006 and 2010 and followed until October 2022...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38524766/assessing-the-real-world-long-term-impact-of-lemborexant-on-sleep-quality-in-a-home-based-clinical-study
#19
Seiko Miyata, Kunihiro Iwamoto, Ippei Okada, Akihiro Fujimoto, Yuki Kogo, Daisuke Mori, Manabu Amano, Nao Matsuyama, Kazuki Nishida, Masahiko Ando, Toshiaki Taoka, Shinji Naganawa, Norio Ozaki
PURPOSE: Both subjective and objective evaluations are essential for the treatment of insomnia. Lemborexant has been shown to be effective in the long-term based solely on a subjective basis, and no long-term objective measures have been evaluated under natural sleep conditions. Small, lightweight sleep electroencephalogram (EEG) monitor was used, instead of polysomnography, to objectively evaluate sleep at home 4 and 12 weeks after lemborexant treatment. PATIENTS AND METHODS: Adults and elderly subjects with insomnia disorder, per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, were enrolled in this open-label, single-arm, single-center trial...
2024: Nature and Science of Sleep
https://read.qxmd.com/read/38523835/dietary-habits-depression-and-obesity-an-intricate-relationship-to-explore-in-pediatric-preventive-strategies
#20
REVIEW
Valeria Calcaterra, Virginia Rossi, Vittoria Carlotta Magenes, Paola Baldassarre, Roberta Grazi, Martina Loiodice, Valentina Fabiano, Gianvincenzo Zuccotti
Obesity and depression represent major health problems due to their high prevalence and morbidity rates. Numerous evidences elucidated the connections between dietary habits and the incidence or severity of depression. This overview aims to investigate the intricate relationship between dietary patterns and depression with the objective of elaborating preventive strategies for childhood obesity. Literature data recognized that there is a link between mood and food choices, with certain foods selected for their impact on the brain's reward centers...
2024: Frontiers in Pediatrics
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