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Cerebral hemorrhage

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https://www.readbyqxmd.com/read/29684516/reconsideration-of-neurogenic-pulmonary-oedema-as-a-source-of-metastatic-cerebral-abscess-following-subarachnoid-hemorrhages-a-preliminary-study
#1
Ahmet Gökyar, Mehmet D Aydın, Sevilay Özmen, Elif Demirci, Abdullah H Marangoz, Enis Kuruoğlu, Cengiz Çokluk
BACKGROUND: Subarachnoid hemorrhage (SAH) may be a cause of neurogenic pulmonary edema (NPE). It is well known that lymphatic fluid draining by thoracic duct to lungs consists of many dangerous metabolites, degraded tissue particles and microbiological pathogens. However, there is no enough study which investigates if NPE cause septicemia or not. In this study, we retrospectively examined our experimental materials whether there is a meaningful relationship between the NPE and cerebral abscess formation...
April 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29683965/effect-of-dexmedetomidine-on-cerebral-vasospasm-and-associated-biomarkers-in-a-rat-subarachnoid-hemorrhage-model
#2
Young Song, Beom Jin Lim, Do-Hyeong Kim, Jin Woo Ju, Dong Woo Han
BACKGROUND: The α2 adrenergic agonist dexmedetomidine (DEX) has huge potential for protecting against cerebral vasospasm, a leading cause of death and disability after subarachnoid hemorrhage (SAH). Biomarker assays for SAH have recently emerged as tools for predicting vasospasm and outcomes. We investigated the effects of DEX on vasospasm and assessed relevant biomarkers in a rat SAH model. METHODS: Male Wistar rats were randomly assigned to sham (n=10), vehicle (n=10), SAH (n=10), or SAH+ DEX (n=10) groups...
April 20, 2018: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/29682077/intracerebral-hemorrhage-with-multiple-intracranial-arterial-stenoses-in-a-synthetic-cannabinoid-spice-user
#3
Seckin Aydin, Odhan Yuksel, Aysegul Esen Aydin, Osman Kizilkilic, Suat Erol Celik
Synthetic cannabinoids (spice), which are used frequently worldwide, are more potent than herbal compounds and also have more side effects in comparison. A 23-year-old male was admitted to the emergency unit with altered consciousness. There was no sign of trauma, and his medical history did not reveal any chronic illness. Computed tomography revealed a large frontal hematoma extending to the ventricular system. The outcomes of cerebral angiography were consistent with multiple intracranial arterial stenoses (MIAS) which can also be seen after cannabis usage...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29682069/ruptured-distal-anterior-choroidal-artery-aneurysm-presenting-as-isolated-intraventricular-hemorrhage-case-report-and-comprehensive-review-of-the-literature
#4
Chi Hau Tan, Leon T Lai, Ronil V Chandra
Distal anterior choroidal artery (AChA) aneurysms are infrequent. We discuss the case of a 59-year-old patient who presented with an isolated intraventricular hemorrhage (IVH) secondary to a ruptured distal AChA aneurysm. Initial noninvasive cerebral computed tomography angiography revealed no evidence of an underlying vascular pathology. The patient underwent further digital subtraction cerebral angiography, which revealed an aneurysm arising from the distal AChA segment. The aneurysm was successfully treated with surgical clip ligation...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29682058/hemispheric-infarct-following-a-cerebellar-hematoma-a-rare-coincidence
#5
R Girish Menon, Vinod Kumar, I K Laskhman, Rajesh P Nair
Concomitant cerebral infarction developing soon after a parenchymal intracerebral hemorrhage is a rare occurrence. Usually, these remote site changes follow tumor decompression and are associated with hemorrhagic changes rather than infarcts. We report a case of a fatal malignant internal carotid territory infarct in a hospitalized patient being conservatively managed for a vermian hematoma and discuss the probable pathophysiology. Stroke physicians need to be aware that spontaneous intracerebral hematoma patients have a potential threat of developing large vessel occlusion with malignant cerebral infarcts, especially after surgical decompression...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29682020/morphometric-analysis-of-dose-dependent-effect-of-progesterone-on-experimental-vasospasm-induced-rat-femoral-arteries
#6
Metin Kasap, Huseyin Canaz, Gokhan Canaz, Mehmet Tokmak, Alper Bingul, Ibrahim Alatas
Objective: Our aim of this study was to determine effective doses of progesterone which has a vasodilatory effect during the early stage of vasospasm. Cerebral vasospasm (CV) is a predominant cause of morbidity and mortality which develops following subarachnoidal hemorrhage (SAH). Etiopathogenesis of CV is multifactorial. Despite many previously performed studies on this issue, the mechanism by which blood and blood products in the subarachnoidal space induce CV has not been clarified yet...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29682015/spinal-cerebrospinal-fluid-drainage-for-prevention-of-vasospasm-in-aneurysmal-subarachnoid-hemorrhage-a-prospective-randomized-controlled-study
#7
Sachin Anil Borkar, Manmohanjit Singh, Shashank Sharad Kale, Ashish Suri, Poodipedi Sarat Chandra, Rajender Kumar, Bhawani Shankar Sharma, Shailesh Gaikwad, Ashok Kumar Mahapatra
Introduction: Cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH) is a major cause of mortality and morbidity. Despite various treatment modalities, the optimal management of vasospasm remains elusive. In this regard; we undertook a prospective, randomized controlled study to evaluate the effectiveness of lumbar cerebrospinal fluid drainage (LCSFD) for prevention of cerebral vasospasm and its sequelae. Materials and Methods: Patients with aneurysmal SAH who met the inclusion criteria were randomized into two groups - Group I (30 patients) underwent LCSFD whereas Group II (30 patients) did not undergo LCSFD...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29681881/factors-associated-with-remote-diffusion-weighted-imaging-lesions-in-spontaneous-intracerebral-hemorrhage
#8
Xiang-Hua Ye, Ting Gao, Xu-Hua Xu, Jin-Song Cai, Jia-Wen Li, Kai-Ming Liu, Shui-Jiang Song, Xin-Zhen Yin, Lu-Sha Tong, Feng Gao
Background and purpose: Remote diffusion-weighted imaging lesions (R-DWILs) have been detected in patients with spontaneous intracerebral hemorrhage (ICH) and may be correlated with clinical outcome. However, the mechanisms and characteristics of R-DWILs have not been fully elucidated. In this study, we sought to demonstrate the clinical characteristics of R-DWILs in spontaneous ICH. Methods: We prospectively collected data with spontaneous ICH patients from November 2016 to December 2017...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29681849/danhong-injection-combined-with-t-pa-improves-thrombolytic-therapy-in-focal-embolic-stroke
#9
Min Li, Jing Zhou, Weifeng Jin, Xiaohong Li, Yuyan Zhang
Background: Hemorrhagic transformation, neurotoxicity, short treatment time windows, and other defects are considered as the major limitations for the thrombolytic therapy. This study is devoted to figure out whether Danhong injection (DHI) combined with tissue-plasminogen activator (t-PA) could extend the treatment time windows and ameliorate brain injury, hemorrhagic complication and BBB disruption after focal embolic stroke. Methods: In vitro , the combined concentrations of DHI and t-PA were added to wells reacted with plasminogen and D-Val-Leu-Lys-AMC...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29681826/frontal-phonological-agraphia-and-acalculia-with-impaired-verbal-short-term-memory-due-to-left-inferior-precentral-gyrus-lesion
#10
Yasuhisa Sakurai, Emi Furukawa, Masanori Kurihara, Izumi Sugimoto
We report a patient with phonological agraphia (selective impairment of kana [Japanese phonetic writing] nonwords) and acalculia (mental arithmetic difficulties) with impaired verbal short-term memory after a cerebral hemorrhage in the opercular part of the left precentral gyrus (Brodmann area 6) and the adjacent postcentral gyrus. The patient showed phonemic paragraphia in five-character kana nonword writing, minimal acalculia, and reduced digit and letter span. Mental arithmetic normalized after 8 months and agraphia recovered to the normal range at 1 year after onset, in parallel with an improvement of the auditory letter span score from 4 to 6 over a period of 14 months and in the digit span score from 6 to 7 over 24 months...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29681825/arterial-spin-labeling-imaging-of-a-giant-aneurysm-leading-to-subarachnoid-hemorrhage-following-cerebral-infarction
#11
Tatsuya Ueno, Tatsuya Sasaki, Masatoshi Iwamura, Tomoya Kon, Jin-Ichi Nunomura, Hiroshi Midorikawa, Masahiko Tomiyama
An 83-year-old Japanese man was admitted with dysarthria and right hemiparesis. He had had a large intracranial aneurysm on the left internal carotid artery 5 years before admission and had been followed up under conservative treatment. On admission, diffusion-weighted imaging revealed a hyperintense signal on the left anterior choroidal artery territory. Time-of-flight magnetic resonance angiography demonstrated poor visibility of the middle and anterior cerebral arteries and the inferior giant aneurysm, suggesting distal emboli from aneurysm thrombosis or a reduction of blood outflow due to aneurysm thrombosis...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29680471/the-neu-prem-trial-neuromonitoring-of-brains-of-infants-born-preterm-during-resuscitation-a-prospective-observational-cohort-study
#12
Anup C Katheria, M J Harbert, Sunil B Nagaraj, Kathy Arnell, Debra M Poeltler, Melissa K Brown, Wade Rich, Kasim O Hassen, Neil Finer
OBJECTIVE: To determine whether monitoring cerebral oxygen tissue saturation (StO2 ) with near-infrared spectroscopy (NIRS) and brain activity with amplitude-integrated electroencephalography (aEEG) can predict infants at risk for intraventricular hemorrhage (IVH) and death in the first 72 hours of life. STUDY DESIGN: A NIRS sensor and electroencephalography leads were placed on 127 newborns <32 weeks of gestational age at birth. Ten minutes of continuous NIRS and aEEG along with heart rate, peripheral arterial oxygen saturation, fraction of inspired oxygen, and mean airway pressure measurements were obtained in the delivery room...
April 16, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29680304/spinal-dural-arteriovenous-fistula-assumed-to-be-symptomatic-after-placement-of-lumbar-cerebrospinal-fluid-drain
#13
Senshu Nonaka, Hidenori Oishi, Satoshi Tsutsumi, Koichiro Sakamoto, Hidehiro Okura, Takamoto Suzuki, Hisato Ishii, Yukimasa Yasumoto
A 69-year-old man presented with severe headache. Cranial computed tomography revealed diffuse subarachnoid hemorrhage. An anterior communicating artery aneurysm was identified and successfully obliterated by open microsurgery on the same day. Following placement of a continuous lumbar cerebrospinal fluid drain on hospitalization day 7, the patient developed a severe paraplegia and sensory loss below T6. Cerebral magnetic resonance imaging did not identify a responsible lesion. Spinal magnetic resonance imaging, however, showed extensive intramedullary hyperintensity on T2-weighted sequences...
April 18, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29679001/nonaneurysmal-perimesencephalic-subarachnoid-hemorrhage-as-an-atypical-initial-presentation-of-cerebral-venous-sinus-thrombosis-a-case-report
#14
Roaa R Amer, Eman A Bakhsh
BACKGROUND Subarachnoid hemorrhage is rarely the first presentation of cerebral venous sinus thrombosis. This case study emphasizes the presentation of perimesencephalic subarachnoid hemorrhage due to cerebral venous sinus thrombosis and the importance of neurovascular imaging for reliable diagnosis of nonaneurysmal perimesencephalic subarachnoid hemorrhage due to cerebral venous sinus thrombosis. CASE REPORT We describe a case of cerebral venous sinus thrombosis manifesting initially as subarachnoid hemorrhage...
April 21, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29678701/seeing-floaters-a-case-report-and-literature-review-of-intraventricular-migration-of-silicone-oil-tamponade-material-for-retinal-detachment
#15
Matthew B Potts, Alex C Wu, David J Rusinak, Kartik Kesavabhotla, Babak S Jahromi
BACKGROUND: Intraocular injection of silicone oil is commonly performed during vitrectomy to tamponade the retina in place for treatment of retinal detachment. Although rare, this intravitreal silicone can migrate through the optic nerve and chiasm and enter the cerebral ventricles. CASE DESCRIPTION: Here we present a case report of a patient presenting with headache and intraventricular hyperdensities on computed tomography imaging raising concern for intraventricular hemorrhage...
April 17, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29673456/-intracerebroventricular-injection-of-mir-7-inhibits-secondary-brain-injury-induced-by-intracerebral-hemorrhage-via-egfr-stat3-pathway-in-rats
#16
Hong Qian, Ke Hu, Ming Xie, Heng Wu, Wenjun Li, Bin Wu, Rongyong Man, Meng Nie
Objective To observe the effects of microRNA-7 (miR-7) on intracerebral hemorrhage-induced brain injury in rats and explore the underlying mechanism. Methods Seventy-five SD rats were used to establish intracerebral hemorrhage model through injection of VII collagenase into the pallidum. These rats were then divided into control, miR-7 agomir, agomir control, miR-7 antagomir and antagomir control groups, containing 15 animals in each group. On day 2 after modeling, rats were injected with 10 μL of physiological saline, miR-7 agomir, agomir control, miR-7 antagomir and antagomir control via the lateral ventricle, respectively...
February 2018: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/29672624/anatomical-distribution-of-cerebral-microbleeds-and-intracerebral-hemorrhage-in-vertebrobasilar-dolichoectasia
#17
Alex Förster, Ralf Wenz, Máté Elöd Maros, Johannes Böhme, Mansour Al-Zghloul, Angelika Alonso, Christoph Groden, Holger Wenz
OBJECTIVES: Vertebrobasilar dolichoectasia (VBD) is a dilatative arteriopathy associated with intracerebral hemorrhage. In the present study, we sought to evaluate the frequency and anatomical distribution of cerebral microbleeds (cMBs) and intracerebral hemorrhage (ICH) in VBD. METHODS: From a MRI database 94 VBD patients were identified and analyzed with special emphasis on cMBs and ICH on T2*-weighted gradient echo images (GRE) in relation to the established diagnostic MRI criteria of VBD (diameter, height, and lateral position)...
2018: PloS One
https://www.readbyqxmd.com/read/29672312/impact-of-brain-atrophy-on-early-neurological-deterioration-and-outcome-in-severe-ischemic-stroke-treated-by-intravenous-thrombolysis
#18
Olivier Tschirret, Gabriela Moreno Legast, Adeline Mansuy, Nathan Mewton, Marielle Buisson, Salem Hannoun, Leila Chamard, Dominique Sappey-Marinier, Carlos El Khoury, Magali Bischoff, Audrey de Parisot, Laurent Derex, Norbert Nighoghossian, Yves Berthezène, Laura Mechtouff
BACKGROUND: Brain atrophy has shown a protective effect on the risk of early neurological deterioration (END) related to malignant edema in patients with hemispheric infarction but could be deleterious on the outcome. AIMS: We aimed to assess whether brain atrophy has an impact on the risk of END and on the outcome in severe ischemic strokes after intravenous (IV) thrombolysis. METHODS: From a prospective thrombolysis registry, 137 patients who had a National Institutes of Health Stroke Scale (NIHSS) ≥15, MRI at admission, and IV thrombolysis were included...
April 19, 2018: European Neurology
https://www.readbyqxmd.com/read/29671828/nf-%C3%AE%C2%BAb-mediated-inflammation-in-the-pathogenesis-of-intracranial-aneurysm-and-subarachnoid-hemorrhage-does-autophagy-play-a-role
#19
REVIEW
Elzbieta Pawlowska, Joanna Szczepanska, Karol Wisniewski, Paulina Tokarz, Dariusz J Jaskólski, Janusz Blasiak
The rupture of saccular intracranial aneurysms (IA) is the commonest cause of non-traumatic subarachnoid hemorrhage (SAH)&mdash;the most serious form of stroke with a high mortality rate. Aneurysm walls are usually characterized by an active inflammatory response, and NF-&kappa;B (nuclear factor kappa-light-chain-enhancer of activated B cells) has been identified as the main transcription factor regulating the induction of inflammation-related genes in IA lesions. This transcription factor has also been related to IA rupture and resulting SAH...
April 19, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29670570/mexican-national-institute-of-neurology-and-neurosurgery-stroke-registry-results-of-a-25-year-hospital-based-study
#20
Antonio Arauz, Juan Manuel Marquez-Romero, Miguel A Barboza, Fabiola Serrano, Carol Artigas, Luis Manuel Murillo-Bonilla, Carlos Cantú-Brito, José Luis Ruiz-Sandoval, Fernando Barinagarrementeria
Background and purpose: Stroke has been scarcely studied in Latin America (LA). The Mexican Institute of Neurology Stroke Registry was established in 1990 as a prospective computer-based database to register data obtained from patients admitted with stroke. Using this data, we attempted to define the profile of risk factors and outcomes. Methods: The demographic data, stroke description, ancillary tests, vascular risk factors, and modified Rankin scale (mRs) were registered...
2018: Frontiers in Neurology
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