Anna Michalczyk, Ernest Tyburski, Piotr Podwalski, Katarzyna Waszczuk, Krzysztof Rudkowski, Jolanta Kucharska-Mazur, Monika Mak, Katarzyna Rek-Owodziń, Piotr Plichta, Maksymilian Bielecki, Wojciech Andrusewicz, Elżbieta Cecerska-Heryć, Agnieszka Samochowiec, Błażej Misiak, Leszek Sagan, Jerzy Samochowiec
Peripheral cytokines may affect the brain through chronic activation of microglia and, as a result, can potentially lead to decreased integrity of white matter of cingulum bundle (CB). Therefore, the aim of the study was to analyze the relationships between peripheral inflammatory markers and the integrity of the CB in various states: from healthy controls, through prodromal states and first-episode psychosis, to long-term schizophrenia. The integrity of the CB was measured using diffusion tensor imaging. We analyzed six parameters: CRP, IL-6, IL-8, IL-10, TNF-α, and IFN-γ...
October 27, 2022: Journal of Clinical Medicine