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https://www.readbyqxmd.com/read/28351023/effect-of-door-locking-policy-on-inpatient-treatment-of-substance-use-and-dual-disorders
#1
Regine Steinauer, Christian G Huber, Sylvie Petitjean, Gerhard A Wiesbeck, Kenneth M Dürsteler, Undine E Lang, Christian Seifert, Katja Andreeff, Michael Krausz, Marc Walter, Marc Vogel
OBJECTIVE: Substance use treatment is often performed inside locked wards. We investigate the effects of adopting a policy of open-door treatment for a substance use treatment and dual diagnosis ward. METHODS: This is a prospective open-label study investigating 3-month study periods before opening (P1), immediately after (P2), and 1 year after the first period (P3). Data on committed patients, coercion (seclusion, forced medication, absconding events with subsequent police search), violence, and substance use was collected daily...
March 29, 2017: European Addiction Research
https://www.readbyqxmd.com/read/28350970/mannheim-peritonitis-index-mpi-and-elderly-population-prognostic-evaluation-in-acute-secondary-peritonitis
#2
G Salamone, L Licari, N Falco, G Augello, R Tutino, S Campanella, G Guercio, G Gulotta
INTRODUCTION: Acute Secondary Peritonitis due to abdominal visceral perforation is characterized by high mortality and morbidity risk. Risk stratification allows prognosis prediction to adopt the best surgical treatment and clinical care support therapy. In Western countries elderly people represent a significant percentage of population Aim. Evaluation of Mannheim Peritonitis Index (MPI) and consideration upon old people. PATIENTS AND METHODS: Retrospective study on 104 patients admitted and operated for "Acute Secondary Peritonitis due to visceral perforation"...
November 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/28350825/antarctica-and-the-strategic-plan-for-biodiversity
#3
Steven L Chown, Cassandra M Brooks, Aleks Terauds, Céline Le Bohec, Céline van Klaveren-Impagliazzo, Jason D Whittington, Stuart H M Butchart, Bernard W T Coetzee, Ben Collen, Peter Convey, Kevin J Gaston, Neil Gilbert, Mike Gill, Robert Höft, Sam Johnston, Mahlon C Kennicutt, Hannah J Kriesell, Yvon Le Maho, Heather J Lynch, Maria Palomares, Roser Puig-Marcó, Peter Stoett, Melodie A McGeoch
The Strategic Plan for Biodiversity, adopted under the auspices of the Convention on Biological Diversity, provides the basis for taking effective action to curb biodiversity loss across the planet by 2020-an urgent imperative. Yet, Antarctica and the Southern Ocean, which encompass 10% of the planet's surface, are excluded from assessments of progress against the Strategic Plan. The situation is a lost opportunity for biodiversity conservation globally. We provide such an assessment. Our evidence suggests, surprisingly, that for a region so remote and apparently pristine as the Antarctic, the biodiversity outlook is similar to that for the rest of the planet...
March 2017: PLoS Biology
https://www.readbyqxmd.com/read/28350714/multiple-transportable-carbohydrate-impact-on-long-distance-triathlon-performance
#4
David S Rowlands, Stuart D Houltham
The ingestion of multiple (2:1 glucose:fructose) transportable carbohydrate in beverages at high rates (>78 g·h) during endurance exercise enhances exogenous carbohydrate oxidation, fluid absorption, gut comfort, and performance, relative to glucose alone. But during long-distance endurance competition, athletes prefer a solid-gel-drink format, and the effect size of multiple-transportable carbohydrate is unknown. PURPOSE: To determine the effect of multiple-transportable carbohydrate on triathlon competition performance when ingested within bars, gels, and drinks...
March 27, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28350637/physician-perception-of-the-role-of-the-patient-portal-in-pediatric-health
#5
Ruth A Bush, Cynthia D Connelly, Alexa Pérez, Neilson Chan, Cynthia Kuelbs, George J Chiang
The patient portal, increasingly available to patients, allows secure electronic communication with physicians. Although physician attitude toward the portal plays a crucial role in patient adoption, little information regarding physician opinion of the portal is available, with almost no information gathered in the pediatric environment. Using a mixed-methods approach, physicians in a large pediatric medical facility and integrated delivery network were surveyed using an online quantitative questionnaire and structured interviews...
March 27, 2017: Journal of Ambulatory Care Management
https://www.readbyqxmd.com/read/28350564/optrust-validity-of-a-tool-assessing-intraoperative-entrustment-behaviors
#6
Gurjit Sandhu, Vahagn C Nikolian, Christopher P Magas, Robert B Stansfield, Danielle C Sutzko, Kaustubh Prabhu, Niki Matusko, Rebecca M Minter
OBJECTIVE: The aim of this study is to establish evidence to support the validity of a novel faculty-resident intraoperative assessment tool for entrustment known as OpTrust. BACKGROUND: Recently, the landscape of surgical training has been altered, in part, because of resident work-hour changes and increased supervision requirements. To address these concerns, a new model for assessment of teaching and learning in surgical residencies must be anchored on progression through milestones and entrustment...
March 27, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28350484/variability-in-radiation-dose-from-repeat-identical-ct-examinations-longitudinal-analysis-of-2851-patients-undergoing-12-635-thoracoabdominal-ct-scans-in-an-academic-health-system
#7
Achille Mileto, Rendon C Nelson, Douglas G Larson, Ehsan Samei, Joshua M Wilson, Olav Christianson, Daniele Marin, Daniel T Boll
OBJECTIVE: The purpose of this study was to conduct longitudinal analyses of radiation dose data from adult patients undergoing clinically indicated, repeat identical thoracoabdominal CT examinations. MATERIALS AND METHODS: Radiation dose data were electronically collected from 2851 subjects undergoing 12,635 repeat identical CT scans (mean number of scans per patient, 4.8; range, 2-33) in one health system. Included CT protocols were chest-abdomen-pelvis with contrast administration (n = 4621 CT studies of 1064 patients), abdomen-pelvis with contrast administration (n = 876 CT studies of 261 patients), renal stone (n = 1053 CT studies of 380 patients), and chest (n = 6085 CT studies of 1146 patients) without contrast administration...
March 28, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28346886/simultaneous-determination-of-amitraz-chlordimeform-formetanate-and-their-main-metabolites-in-human-urine-by-high-performance-liquid-chromatography-tandem-mass-spectrometry
#8
Xue Gao, Yanglan Tan, Hao Guo
A rapid, simple and reliable high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was developed for simultaneous determination of amitraz, chlordimeform, formetanate and their main metabolites, N-(2,4-dimethylphenyl)-N-methyl-formamidine (DMPF), 2,4-dimethylformamidine (DMF), 2,4-dimethylaniline (DMA), 4-chloro-2-methylaniline and 3-hydroxyacetanilide in human urine. The urine samples were mixed with buffer solutions (pH 8) and subsequently cleaned up by solid supported liquid/liquid extraction (SLE)...
March 11, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28346875/helicobacter-pylori-infection-detection-from-gastric-x-ray-images-based-on-feature-fusion-and-decision-fusion
#9
Kenta Ishihara, Takahiro Ogawa, Miki Haseyama
In this paper, a fully automatic method for detection of Helicobacter pylori (H. pylori) infection is presented with the aim of constructing a computer-aided diagnosis (CAD) system. In order to realize a CAD system with good performance for detection of H. pylori infection, we focus on the following characteristic of stomach X-ray examination. The accuracy of X-ray examination differs depending on the symptom of H. pylori infection that is focused on and the position from which X-ray images are taken. Therefore, doctors have to comprehensively assess the symptoms and positions...
March 21, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28346759/commentary-what-s-in-a-word-or-words-on-the-relations-among-self-regulation-self-control-executive-functioning-effortful-control-cognitive-control-impulsivity-risk-taking-and-inhibition-for-developmental-psychopathology-reflections-on-nigg-2017
#10
Nancy Eisenberg
In Nigg's excellent article, he deals with a variety of complex conceptual issues related to the constructs of self-regulation and executive functioning (EF). Overall, I agree that the terminology proposed by Nigg should be adopted; moreover, the conceptual distinctions he provides should help the field to move forward with regard to the understanding of varied constructs related to self-regulation. In the spirit of further clarification, I questioned Nigg's suggestions that (a) working memory should be considered as part of the construct of top-down regulation and (b) planning is a higher level component of EF but not part of effortful control...
April 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28346691/reproductive-status-affects-the-feeding-ecology-and-social-association-patterns-of-female-squirrel-monkeys-saimiri-collinsi-in-an-amazonian-rainforest
#11
Luana V P Ruivo, Anita I Stone, Matthew Fienup
When making foraging decisions, female primates may follow specific behavioral strategies that reflect their reproductive state. Lactation is considered the most energetically costly phase for females, but we argue that gestation is also energetically expensive for squirrel monkeys. In this study, we examined whether female squirrel monkeys (a seasonally breeding primate) in different reproductive phases showed significant differences in their foraging ecology. We sampled two wild groups of squirrel monkeys (Saimiri collinsi) using the focal animal method, during 12 months (June 2014 to May 2015)...
March 27, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28346425/chip-stub1-regulates-the-warburg-effect-by-promoting-degradation-of-pkm2-in-ovarian-carcinoma
#12
Y Shang, J He, Y Wang, Q Feng, Y Zhang, J Guo, J Li, S Li, Y Wang, G Yan, F Ren, Y Shi, J Xu, N Zeps, Y Zhai, D He, Z Chang
Tumor cells preferentially adopt aerobic glycolysis for their energy supply, a phenomenon known as the Warburg effect. It remains a matter of debate as to how the Warburg effect is regulated during tumor progression. Here, we show that CHIP (carboxyl terminus of Hsc70-interacting protein), a U-box E3 ligase, suppresses tumor progression in ovarian carcinomas by inhibiting aerobic glycolysis. While CHIP is downregulated in ovarian carcinoma, induced expression of CHIP results in significant inhibition of the tumor growth examined by in vitro and in vivo experiments...
March 27, 2017: Oncogene
https://www.readbyqxmd.com/read/28346400/t-lymphocyte-homing-an-underappreciated-yet-critical-hurdle-for-successful-cancer-immunotherapy
#13
Robert Sackstein, Tobias Schatton, Steven R Barthel
Advances in cancer immunotherapy have offered new hope for patients with metastatic disease. This unfolding success story has been exemplified by a growing arsenal of novel immunotherapeutics, including blocking antibodies targeting immune checkpoint pathways, cancer vaccines, and adoptive cell therapy (ACT). Nonetheless, clinical benefit remains highly variable and patient-specific, in part, because all immunotherapeutic regimens vitally hinge on the capacity of endogenous and/or adoptively transferred T-effector (Teff) cells, including chimeric antigen receptor (CAR) T cells, to home efficiently into tumor target tissue...
March 27, 2017: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/28346385/intelligent-diagnosis-method-for-rotating-machinery-using-dictionary-learning-and-singular-value-decomposition
#14
Te Han, Dongxiang Jiang, Xiaochen Zhang, Yankui Sun
Rotating machinery is widely used in industrial applications. With the trend towards more precise and more critical operating conditions, mechanical failures may easily occur. Condition monitoring and fault diagnosis (CMFD) technology is an effective tool to enhance the reliability and security of rotating machinery. In this paper, an intelligent fault diagnosis method based on dictionary learning and singular value decomposition (SVD) is proposed. First, the dictionary learning scheme is capable of generating an adaptive dictionary whose atoms reveal the underlying structure of raw signals...
March 27, 2017: Sensors
https://www.readbyqxmd.com/read/28346373/harmful-use-of-alcohol-a-shadow-over-sub-saharan-africa-in-need-of-workable-solutions
#15
Carina Ferreira-Borges, Charles D H Parry, Thomas F Babor
Alcohol consumption and alcohol-attributable burden of disease in Africa are expected to rise in the near future, yet. increasing alcohol-related harm receives little attention from policymakers and from the population in general. Even where new legislation is proposed it is rarely enacted into law. Being at the center of social and cultural activities in many countries, alcohol's negative role in society and contribution to countries' burden of disease are rarely questioned. After the momentum created by the adoption in 2010 of the WHO Global Strategy and the WHO Regional Strategy (for Africa) to Reduce the Harmful Use of Alcohol, and the WHO Global Action Plan for the Prevention and Control of Non-Communicable Diseases, in 2013, little seems to have been done to address the increasing use of alcohol, its associated burden and the new challenges that derive from the growing influence of the alcohol industry in Africa...
March 27, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28346336/enzymatic-processes-in-marine-biotechnology
#16
REVIEW
Antonio Trincone
In previous review articles the attention of the biocatalytically oriented scientific community towards the marine environment as a source of biocatalysts focused on the habitat-related properties of marine enzymes. Updates have already appeared in the literature, including marine examples of oxidoreductases, hydrolases, transferases, isomerases, ligases, and lyases ready for food and pharmaceutical applications. Here a new approach for searching the literature and presenting a more refined analysis is adopted with respect to previous surveys, centering the attention on the enzymatic process rather than on a single novel activity...
March 25, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28346133/creating-a-climate-that-catalyses-healthcare-innovation-in-the-united-kingdom-learning-lessons-from-international-innovators
#17
Kathrin Cresswell, Sarah Cunningham-Burley, Aziz Sheikh
BACKGROUND: The United Kingdom (UK) lags behind other high-income countries in relation to technological innovation in healthcare. In order to inform UK strategy on how to catalyse innovation, we sought to understand what national strategies can help to promote a climate for innovation in healthcare settings by extracting lessons for the UK from international innovators. METHODS: We undertook a series of qualitative semi-structured interviews with senior international innovators from a range of health related policy, care/service delivery, commercial and academic backgrounds...
January 25, 2017: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28346131/lack-of-diversity-in-personal-health-record-evaluations-with-older-adult-participants-a-systematic-review-of-literature
#18
Laura Kneale, George Demiris
BACKGROUND: Older adults are not adopting personal health records (PHRs) at the same rates as other adult populations. Disparities in adoption rates are also reported in older adult subgroups. The variability in adoption may be because PHRs are not designed to meet older adult users. OBJECTIVE: We analyzed PHR evaluation studies to examine the characteristics and perspectives of older adult study participants to identify their self-reported needs. METHOD: We searched Medline, CINAHL, PsycINFO, and Embase for PHR evaluation studies that involved older adult participants...
January 15, 2017: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28346109/assessing-process-of-paediatric-care-in-a-resource-limited-setting-a-cross-sectional-audit-of-district-hospitals-in-rwanda
#19
Celestin Hategeka, Jeannie Shoveller, Lisine Tuyisenge, Larry D Lynd
BACKGROUND: Routine assessment of quality of care helps identify deficiencies which need to be improved. While gaps in the emergency care of children have been documented across sub-Saharan Africa, data from Rwanda are lacking. OBJECTIVE: To assess the care of sick infants and children admitted to Rwandan district hospitals and the extent to which it follows currently recommended clinical practice guidelines in Rwanda. METHODS: Data were gathered during a retrospective cross-sectional audit of eight district hospitals across Rwanda in 2012/2013...
March 27, 2017: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/28345927/stable-superwetting-meshes-for-on-demand-separation-of-immiscible-oil-water-mixtures-and-emulsions
#20
Mingming Liu, Yuanyuan Hou, Jing Li, Zhiguang Guo
Oil-water separation is of great importance for the treatment of oily wastewater, including immiscible light/heavy oil-water mixtures, oil-in-water or water-in-oil emulsions. Recently, interfacial materials (especially filtration membranes) with special wettability have been broadly developed to solve the environmental problems by virtue of their advantages in energy saving, high flux and good selectivity. However, the given wetting property (superhydrophilicity or superhydrophobicity) and pore size and poor stability of filtration membranes limit their widespread applications, which is far from meeting a wide variety of oil polluted water...
March 27, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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