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https://www.readbyqxmd.com/read/29787036/reflections-of-a-black-african-insider-researcher
#1
Isaac Tuffour
BACKGROUND: There is a growing body of literature providing reflective accounts and critical examination of the challenges faced by insider researchers. However, there is little research about the specific challenges that black African insider nurse researchers face. AIM: To reflect on the complexities black African insider nurse researchers face in the context of research sites, participants and the interpretation of data. DISCUSSION: Insider researchers are susceptible to various entanglements and dilemmas...
May 22, 2018: Nurse Researcher
https://www.readbyqxmd.com/read/29786728/selenization-of-nimn-layered-double-hydroxide-with-enhanced-electrocatalytic-activity-for-oxygen-evolution
#2
Jing Du, Zehua Zou, Ailing Yu, Cailing Xu
Exploiting highly active oxygen evolution reaction electrocatalysts is of great importance in the cost-effective generation of clean fuels. Herein, the preparation of NiMn-layered double hydroxide with selenization is adopted to reduce the charge transfer resistance of the electrocatalytic oxygen evolution reaction and enhance electrocatalytic performance. As a result, this selenization product of NiMn-layered double hydroxide can reach a current density of 10 mA cm-2 at a low overpotential of 280 mV on glassy carbon electrode in 1...
May 22, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29786695/the-asthma-mobile-health-study-smartphone-data-collected-using-researchkit
#3
Yu-Feng Yvonne Chan, Brian M Bot, Micol Zweig, Nicole Tignor, Weiping Ma, Christine Suver, Rafhael Cedeno, Erick R Scott, Steven Gregory Hershman, Eric E Schadt, Pei Wang
Widespread adoption of smart mobile platforms coupled with a growing ecosystem of sensors including passive location tracking and the ability to leverage external data sources create an opportunity to generate an unprecedented depth of data on individuals. Mobile health technologies could be utilized for chronic disease management as well as research to advance our understanding of common diseases, such as asthma. We conducted a prospective observational asthma study to assess the feasibility of this type of approach, clinical characteristics of cohorts recruited via a mobile platform, the validity of data collected, user retention patterns, and user data sharing preferences...
May 22, 2018: Scientific Data
https://www.readbyqxmd.com/read/29786677/-combined-rehabilitation-in-the-patients-presenting-with-dorsopathies-of-the-lumbar-spine-and-concomitant-irritable-bowel-syndrome-based-at-a-therapeutic-clinic
#4
E V Sevostyanova, Y A Nikolaev, N V Bogdankevich, V G Lusheva, N A Dolgova, V Y Polyakov
BACKGROUND: Comorbidity constitutes a serious challenge for rehabilitative medicine. The comorbidity of the dorsopathy of the lumbar spine and irritable bowel syndrome mutually complicates the clinical course of both conditions, significantly reduces the patients' quality of life. and increases the costs of diagnostic procedures and restoration of the working capacity. The approaches to the non-pharmacological management of the patients presenting with these diseases remain to be developed...
May 21, 2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29786630/effect-of-cadence-on-time-trial-performance-in-recreational-female-cyclists
#5
Patricia L Graham, Robert F Zoeller, Patrick L Jacobs, Michael A Whitehurst
Graham, PL, Zoeller, RF, Jacobs, PL, and Whitehurst, MA. Effect of cadence on time trial performance in recreational female cyclists. J Strength Cond Res 32(6): 1739-1744, 2018-The impact of pedaling cadence on cycling performance remains unresolved especially in female cyclists. The purpose of this study was to determine the effect of cadence on time trial (TT) performance in recreational female cyclists. Ten recreational female cyclists volunteered to participate in this study. Subjects performed 3 exercise sessions: 1 to assess peak oxygen uptake (V[Combining Dot Above]O2peak) and 2 TTs...
June 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29786593/reproductive-function-the-protection-of-the-rights-of-the-people-which-are-sent-to-the-area-of-the-fighting
#6
Vitalii Pashkov, Nataliya Gutorova, Petro Noha
OBJECTIVE: Introduction: The issues of problems of the legal regulation of posthumous reproduction in Ukraine and foreign countries are analysis in the article. The author substantiates the necessity in the creation and acceptance of the State Program of the retrieval of reproductive cells in people who are sending to the area of the fighting. The aim:the purpose of our work is a comprehensive study of post-mortem (post-mortem) reproduction and substantiation of the possibility and necessity of adopting a state program for the selection of reproductive cells of individuals who are sent to a combat zone to ensure their full social protection and assistance in the realization of the right to fatherhood or motherhood...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786590/hepatitis-c-and-human-rights-comparison-of-legal-experience-of-ukraine-and-georgia
#7
Iryna Y Senyuta
A comparative legal research of human rights provision in Ukraine and Georgia, in the aspect of combating viral HCV, was conducted. Ukrainian advocacy experience and Georgian strategic litigation experience with regard to human rights and HCV was analyzed. Key international instruments, which lay the conceptual foundations as well as outline the measures, which are directed at human rights in patient care provision and fighting viral hepatitis, were elucidated. Attention was paid to the Global health sector strategy...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786469/estimation-versus-falsification-approaches-in-sport-and-exercise-science
#8
Michael Wilkinson, Edward M Winter
There has been a recent resurgence in debate about methods for statistical inference in science. The debate addresses statistical concepts and their impact on the value and meaning of analyses' outcomes. In contrast, philosophical underpinnings of approaches and the extent to which analytical tools match philosophical goals of the scientific method have received less attention. This short piece considers application of the scientific method to "what-is-the-influence-of x-on-y" type questions characteristic of sport and exercise science...
May 22, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29786080/atomic-structures-of-tdp-43-lcd-segments-and-insights-into-reversible-or-pathogenic-aggregation
#9
Elizabeth L Guenther, Qin Cao, Hamilton Trinh, Jiahui Lu, Michael R Sawaya, Duilio Cascio, David R Boyer, Jose A Rodriguez, Michael P Hughes, David S Eisenberg
The normally soluble TAR DNA-binding protein 43 (TDP-43) is found aggregated both in reversible stress granules and in irreversible pathogenic amyloid. In TDP-43, the low-complexity domain (LCD) is believed to be involved in both types of aggregation. To uncover the structural origins of these two modes of β-sheet-rich aggregation, we have determined ten structures of segments of the LCD of human TDP-43. Six of these segments form steric zippers characteristic of the spines of pathogenic amyloid fibrils; four others form LARKS, the labile amyloid-like interactions characteristic of protein hydrogels and proteins found in membraneless organelles, including stress granules...
May 21, 2018: Nature Structural & Molecular Biology
https://www.readbyqxmd.com/read/29786049/lipoxin-a4-ameliorates-lipopolysaccharide-induced-a549-cell-injury-through-upregulation-of-n-myc-downstream-regulated-gene-1
#10
Jun-Zhi Zhang, Zhan-Li Liu, Yao-Xian Zhang, Hai-Jiu Lin, Zhong-Jun Zhang
Background: Lipoxin A4 (LXA4) can alleviate lipopolysaccharide (LPS)-induced acute lung injury (ALI) and acute respiratory distress syndrome through promoting epithelial sodium channel (ENaC) expression in lung epithelial cells. However, how LXA4 promote ENaC expression is still largely elusive. The present study aimed to explore genes and signaling pathway involved in regulating ENaC expression induced by LXA4. Methods: A549 cells were incubated with LPS and LXA4, or in combination, and analyzed by quantitative real-time polymerase chain reaction (qRT-PCR) of ENaC-α/γ...
June 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29786047/establishment-of-a-quantitative-medical-technology-evaluation-system-and-indicators-within-medical-institutions
#11
Suo-Wei Wu, Tong Chen, Qi Pan, Liang-Yu Wei, Qin Wang, Chao Li, Jing-Chen Song, Ji Luo
Background: The development and application of medical technologies reflect the medical quality and clinical capacity of a hospital. It is also an effective approach in upgrading medical service and core competitiveness among medical institutions. This study aimed to build a quantitative medical technology evaluation system through questionnaire survey within medical institutions to perform an assessment to medical technologies more objectively and accurately, and promote the management of medical quality technologies and ensure the medical safety of various operations among the hospitals...
June 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29785933/a-comparison-of-peripheral-imaging-technologies-for-bone-and-muscle-quantification-a-review-of-segmentation-techniques
#12
REVIEW
Andy Kin On Wong, Sarah Lynn Manske
Musculoskeletal science has developed many overlapping branches, necessitating specialists from 1 area of focus to often require the expertise in others. In terms of imaging, this means obtaining a comprehensive illustration of bone, muscle, and fat tissues. There is currently a lack of a reliable resource for end users to learn about these tissues' imaging and quantification techniques together. An improved understanding of these tissues has been an important progression toward better prediction of disease outcomes and better elucidation of their interaction with frailty, aging, and metabolic disorders...
April 17, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29785721/heeding-humanity-in-an-age-of-electronic-health-records-heidegger-levinas-and-healthcare
#13
Casey Rentmeester
The American Recovery and Reinvestment Act of 2009 (ARRA) required healthcare providers in the United States to adopt and demonstrate meaningful use of electronic health records (EHRs) by January 1, 2014. In many ways, EHRs mark a notable improvement over paper medical records as they are more easily accessible and allow for electronic searching and sharing of medical history. However, as EHRs have become mandated by ARRA, many nurses now rely upon computers far more heavily during nurse-patient interactions, thereby decreasing the level of direct interpersonal communication between the two...
May 21, 2018: Nursing Philosophy: An International Journal for Healthcare Professionals
https://www.readbyqxmd.com/read/29785689/the-impact-of-hospital-costing-methods-on-cost-effectiveness-analysis-a-case-study
#14
José Leal, Stefania Manetti, James Buchanan
BACKGROUND: Several methods exist to cost hospital contacts when estimating the cost effectiveness of a new intervention. However, the implications of choosing a particular approach remain unclear. We compare the use of the three main diagnosis-related group (DRG)-based national unit costs in England to determine whether choice of approach can impact on economic evaluation results. METHODS: A cost-utility model was developed to compare secondary fracture prevention models of care for hip fracture patients, using data from large primary and hospital care administrative datasets in England...
May 22, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29785540/use-of-magnetic-resonance-imaging-in-rectal-cancer-patients-society-of-abdominal-radiology-sar-rectal-cancer-disease-focused-panel-dfp-recommendations-2017
#15
Marc J Gollub, Supreeta Arya, Regina Gh Beets-Tan, Gregory dePrisco, Mithat Gonen, Kartik Jhaveri, Zahra Kassam, Harmeet Kaur, David Kim, Andrea Knezevic, Elena Korngold, Chandana Lall, Neeraj Lalwani, D Blair Macdonald, Courtney Moreno, Stephanie Nougaret, Perry Pickhardt, Shannon Sheedy, Mukesh Harisinghani
PURPOSE: To propose guidelines based on an expert-panel-derived unified approach to the technical performance, interpretation, and reporting of MRI for baseline and post-treatment staging of rectal carcinoma. METHODS: A consensus-based questionnaire adopted with permission and modified from the European Society of Gastrointestinal and Abdominal Radiologists was sent to a 17-member expert panel from the Rectal Cancer Disease-Focused Panel of the Society of Abdominal Radiology containing 268 question parts...
May 21, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29785493/mindset-and-communication-barriers-in-the-diffusion-of-bariatric-surgery
#16
REVIEW
Daniel Gero, Bors Hulesch, Marco Bueter
PURPOSE OF REVIEW: Cumulating evidence is available to demonstrate the efficacy of bariatric surgery (BS) in achieving weight loss and optimizing comorbidities. However, currently, only a minority of eligible patients approaches bariatric centers. The underuse of BS can no longer be explained by the lack of evidence supporting its beneficial outcomes along with its favorable safety-profile, rather, by the supporting infrastructure, insurance coverage, and mindset of society, including potential patients and allied healthcare professionals...
May 21, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29785434/integration-of-phospholipid-hyaluronic-acid-methotrexate-nanocarrier-assembly-and-amphiphilic-drug-drug-conjugate-for-synergistic-targeted-delivery-and-combinational-tumor-therapy
#17
Yang Li, Huabing Zhang, Yilin Chen, Jinyuan Ma, Jinyan Lin, Yinying Zhang, Zhongxiong Fan, Guanghao Su, Liya Xie, Xuan Zhu, Zhenqing Hou
Combinational cancer therapy has been considered as a promising strategy to achieve synergetic therapeutic effects and suppression of multidrug resistance. Herein, we adopted a combination of methotrexate (MTX), an antimetabolite acting on cytoplasm, and 10-hydroxycamptothecin (HCPT), an alkaloid acting on nuclei, to treat cancer. Given the different solubilities, membrane permeabilities, and anticancer mechanisms of both drugs, we developed a dual-targeting delivery system based on 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-hyaluronic acid (a principal ligand of CD44 receptors)-MTX (a selective ligand of folate receptors) nanoparticles, which was exploited to carry HCPT-MTX conjugate for synergistically boosting dual-drug co-delivery...
May 22, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29785431/slow-magnetic-relaxation-and-luminescence-properties-in-lanthanide-iii-anil-complexes
#18
Diamantoula Maniaki, Ioannis Mylonas-Margaritis, Julia Mayans, Aikaterini Savvidou, Catherine P Raptopoulou, Vlasoula Bekiari, Vassilis Psycharis, Albert Escuer, Spyros P Perlepes
The initial use of anils, i.e. bidentate Schiff bases derived from the condensation of anilines with salicylaldehyde or its derivatives, in 4f-metal chemistry is described. The 1 : 1 reactions between Ln(NO3)3·xH2O (Ln = lanthanide) or Y(NO3)3·6H2O and N-(5-bromosalicylidene)aniline (5BrsalanH) in MeCN has provided access to complexes [Ln(NO3)3(5BrsalanH)2(H2O)]·MeCN (Ln = Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Yb) and [Y(NO3)3(5BrsalanH)2(H2O)]·MeCN, respectively, in good yields. The structures of the isomorphous complexes with Ln = Pr(1·MeCN), Sm(3·MeCN), Gd(5·MeCN), Dy(7·MeCN) and Er(9·MeCN) have been determined by single-crystal X-ray crystallography...
May 22, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29785411/low-dose-ct-perfusion-of-the-liver-using-reconstruction-of-difference
#19
Saeed Seyyedi, Eleni Liapi, Tobias Lasser, Robert Ivkov, Rajeev Hatwar, J Webster Stayman
Liver CT perfusion (CTP) is used in the detection, staging, and treatment response analysis of hepatic diseases. Unfortunately, CTP radiation exposures is significant, limiting more widespread use. Traditional CTP data processing reconstructs individual temporal samples, ignoring a large amount of shared anatomical information between temporal samples, suggesting opportunities for improved data processing. We adopt a prior-image-based reconstruction approach called Reconstruction of Difference (RoD) to enable low-exposure CTP acquisition...
May 2018: IEEE Transactions on Radiation and Plasma Medical Sciences
https://www.readbyqxmd.com/read/29785408/stroke-prevalence-in-children-with-sickle-cell-disease-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#20
Lianna J Marks, Deogratias Munube, Philip Kasirye, Ezekiel Mupere, Zhezhen Jin, Philip LaRussa, Richard Idro, Nancy S Green
Objectives . The prevalence of stroke among children with sickle cell disease (SCD) in sub-Saharan Africa was systematically reviewed. Methods . Comprehensive searches of PubMed, Embase, and Web of Science were performed for articles published between 1980 and 2016 (English or French) reporting stroke prevalence. Using preselected inclusion criteria, titles and abstracts were screened and full-text articles were reviewed. Results . Ten full-text articles met selection criteria. Cross-sectional clinic-based data reported 2...
2018: Global Pediatric Health
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