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https://www.readbyqxmd.com/read/28207768/prevalence-of-mdr-pathogens-of-bacterial-meningitis-in-egypt-and-new-synergistic-antibiotic-combinations
#1
Mona M Abdelkader, Khaled M Aboshanab, Marwa A El-Ashry, Mohammad M Aboulwafa
The aim of this study was identifying bacterial pathogens involved in meningitis, studying their antibiotic resistance profiles, investigating the antibiotic resistance genes as well as evaluating the use of various antibiotic combinations. Antibiotic susceptibility tests were evaluated according to CLSI guidelines. Antibiotic combinations were evaluated by calculating the Fractional Inhibitory Concentration (FIC) index. A total of 71 bacterial isolates were recovered from 68 culture positive CSF specimens...
2017: PloS One
https://www.readbyqxmd.com/read/28202637/supplemental-selenium-may-decrease-ovarian-cancer-risk-in-african-american-women
#2
Paul D Terry, Bo Qin, Fabian Camacho, Patricia G Moorman, Anthony J Alberg, Jill S Barnholtz-Sloan, Melissa Bondy, Michele L Cote, Ellen Funkhouser, Kristin A Guertin, Edward S Peters, Ann G Schwartz, Joellen M Schildkraut, Elisa V Bandera
Background: To our knowledge, no previous study has evaluated the associations of antioxidant intake with the risk of ovarian cancer in African-American women, who are known to have high mortality from the disease.Objective: We sought to evaluate these associations among 406 ovarian cancer cases and 632 age- and site-matched controls of African-American descent recruited from AACES (African American Cancer Epidemiology Study), a population-based, case-control study in 11 geographical areas within the United States...
February 15, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28194287/acute-acalculous-cholecystitis-a-rare-presentation-of-primary-epstein-barr-virus-infection-in-adults-case-report-and-review-of-the-literature
#3
Zuhal Yesilbag, Asli Karadeniz, Fatih Oner Kaya
Primary Epstein-Barr virus (EBV) infection is almost always a self-limited disease characterized by sore throat, fever, and lymphadenopathy. Hepatic involvement is usually characterized by mild elevations of aminotransferases and resolves spontaneously. Although isolated gallbladder wall thickness has been reported in these patients, acute acalculous cholecystitis is an atypical presentation of primary EBV infection. We presented a young women admitted with a 10-day history of fever, nausea, malaise who had jaundice and right upper quadrant tenderness on the physical examination...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28193404/influence-of-orange-cultivar-and-mandarin-postharvest-storage-on-polyphenols-ascorbic-acid-and-antioxidant-activity-during-gastrointestinal-digestion
#4
Begoña De Ancos, Antonio Cilla, Reyes Barberá, Concepción Sánchez-Moreno, M Pilar Cano
Polyphenols, ascorbic acid content and antioxidant activity of two sweet oranges (Navel-N and Cara Cara-CC) and mandarin (Clementine-M) as well as their bioaccessibilities were evaluated in pulps and compared to those in fresh juice. Thus, pulps of oranges and mandarins displayed higher hesperidin (HES), narirutin (NAR), total flavonoids (TF), total phenols (TP) and antioxidant activity (AAC) than their corresponding juices. Also, CC products presented higher bioactive compounds content than N ones. Bioaccessibility of bioactive compounds and AAC were higher in pulps of both oranges and mandarin than in their corresponding juices...
June 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28193134/non-coronary-vascular-calcification-bone-mineral-density-and-muscle-mass-in-institutionalized-frail-nonagenarians
#5
Fernando Idoate, Eduardo L Cadore, Alvaro Casas-Herrero, Fabricio Zambom-Ferraresi, Nicolas Martinez-Velilla, Leocadio Rodriguez-Mañas, Pedro M Azkarate, Martim Bottaro, Robison Ramírez-Vélez, Mikel Izquierdo
The purpose of this study was to compare the vascular calcification at thoracic (TAC) and ab-dominal (AAC) aorta, iliac (IAC) and femoral (FAC) arteries, and bone mineral density (BMD) of the lumbar vertebrae between frail and robust nonagenarians, as well as to verify the associations between vascular calcification with BMD, muscle tissue quality and quantity in both groups. Forty-two elderly subjects participated in this study: 29 institutionalized frail (92.0±3.2 years) and 13 ro-bust (89.0±4.0 years) elderly participants...
February 14, 2017: Rejuvenation Research
https://www.readbyqxmd.com/read/28167856/prevalence-of-high-level-gentamicin-resistant-enterococcus-faecalis-and-enterococcus-faecium-in-an-iranian-hospital
#6
M Emaneini, B Khoramian, F Jabalameli, R Beigverdi, K Asadollahi, M Taherikalani, A R Lari
This study was designed to determine the molecular characteristics and antimicrobial resistance of enterococcal strains isolated from patients admitted to an Iranian Hospital. Enterococcal strains were isolated from the burn patients. All strains were screened for genes encoding resistance to aminoglycoside [aac(6')-Ie-aph(2'')-Ia, aph (3'), ant (4')], resistance to vancomycin (vanA, vanB), resistance to tetracycline (tetK, tetL, tetM, tetO), and resistance to erythromycin (ermA, ermB, ermC) by PCR and multiplex PCR-based methods...
December 2016: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/28167530/mutational-analysis-of-the-qrrq-motif-in-the-yeast-hig1-type-2-protein-rcf1-reveals-a-regulatory-role-for-the-cytochrome-c-oxidase-complex
#7
Joshua Garlich, Valentina Strecker, Ilka Wittig, Rosemary A Stuart
The yeast Rcf1 protein is a member of the conserved family of proteins termed the hypoxia induced gene (domain) 1 (Hig1 or HIGD1) family. Rcf1 interacts with components of the mitochondrial oxidative phosphorylation system in particular the cytochrome bc1 (complex III)-cytochrome c oxidase (complex IV) supercomplex (termed III-IV) and the ADP/ATP carrier proteins (AAC). Rcf1 plays a role in the assembly and modulation of the activity of complex IV, however, the molecular basis for how Rcf1 influences the activity of complex IV is currently unknown...
February 6, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28166652/language-learning-recasts-and-interaction-involving-aac-background-and-potential-for-intervention
#8
Michael T Clarke, Gloria Soto, Keith Nelson
For children with typical development, language is learned through everyday discursive interaction. Adults mediate child participation in such interactions through the deployment of a range of co-constructive strategies, including repeating, questioning, prompting, expanding, and reformulating the child's utterances. Adult reformulations of child utterances, also known as recasts, have also been shown to relate to the acquisition of linguistic structures in children with language and learning disabilities and children and adults learning a foreign language...
February 6, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28162903/the-relationship-between-neutrophil-to-lymphocyte-ratio-and-aortic-arch-calcification-in-ischemic-stroke-patients
#9
Shuyu Zhou, Biyang Cai, Yumeng Zhang, Li Wang, Xinfeng Liu, Gelin Xu
BACKGROUND: Inflammation plays a central role in atherogenesis and artery calcification. Although neutrophil-to-lymphocyte ratio (NLR) has been introduced as an inflammatory marker for atherosclerosis, the relationship between NLR and aortic arch calcification (AAC) has not been studied. This study aimed to determine the association between NLR and AAC. METHODS: A total of 749 participants were enrolled. Demographic and clinical data were collected. Degree of AAC in each enrolled patient was determined with Agatston method based on a neck computed tomography angiography...
February 2, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28156151/american-association-of-clinical-endocrinologists-and-american-college-of-endocrinology-guidelines-for-management-of-dyslipidemia-and-prevention-of-atherosclerosis
#10
Paul S Jellinger, Yehuda Handelsman, Paul D Rosenblit, Zachary T Bloomgarden, Vivian A Fonseca, Alan J Garber, George Grunberger, Chris K Guerin, David S H Bell, Jeffrey I Mechanick, Rachel Pessah-Pollack, Kathleen Wyne, Donald Smith, Eliot A Brinton, Sergio Fazio, Michael Davidson
OBJECTIVE: The development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees and adheres with published AACE protocols for the standardized production of clinical practice guidelines (CPGs). METHODS: Each Recommendation is based on a diligent review of the clinical evidence with transparent incorporation of subjective factors. RESULTS: The Executive Summary of this document contains 87 Recommendations of which 45 are Grade A (51...
February 3, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28152610/evidence-and-innovation-in-aac-research-expanding-borders-and-boundaries-for-a-global-audience
#11
Bronwyn Hemsley, Susan Balandin
No abstract text is available yet for this article.
February 3, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28148544/advanced-glycation-end-products-oxidation-products-and-the-extent-of-atherosclerosis-during-the-va-diabetes-trial-and-follow-up-study
#12
Aramesh Saremi, Scott Howell, Dawn C Schwenke, Gideon Bahn, Paul J Beisswenger, Peter D Reaven
OBJECTIVE: To determine whether plasma levels of advanced glycation end products and oxidation products play a role in the development of atherosclerosis in patients with type 2 diabetes (T2D) over nearly 10 years of the VA Diabetes Trial and Follow-up Study. RESEARCH DESIGN AND METHODS: Baseline plasma levels of methylglyoxal hydroimidazolone, Nε-carboxymethyl lysine, Nε-carboxyethyl lysine (CEL), 3-deoxyglucosone hydroimidazolone and glyoxal hydroimidazolone (G-H1), 2-aminoadipic acid (2-AAA), and methionine sulfoxide were measured in a total of 411 participants, who underwent ultrasound assessment of carotid intima-media thickness (CIMT), and computed tomography scanning of coronary artery calcification (CAC) and abdominal aortic artery calcification (AAC) after an average of 10 years of follow-up...
February 1, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28135647/spread-of-esbl-ampc-producing-escherichia-coli-and-klebsiella-pneumoniae-in-the-community-through-ready-to-eat-sandwiches-in-algeria
#13
Lydia Yaici, Marisa Haenni, Véronique Métayer, Estelle Saras, Ferielle Mesbah Zekar, Meriem Ayad, Abdelaziz Touati, Jean-Yves Madec
The spread of Extended-Spectrum β-Lactamases (ESBLs) or AmpC β-Lactamases (AmpC) encoding genes in healthy human populations is of major concern. The role of the food chain has been questioned since numerous studies reported surface contamination of retail meat or crude vegetables with ESBL/AmpC-producing Enterobacteriaceae (ESBL/AmpC-E). Nonetheless, these food products are intended to be cooked or washed before consumption so that the risk of human transfer might be low. Here, the presence of ESBL/AmpC-E was investigated in ready-to-eat (RTE) sandwiches purchased in the street in the city of Bejaia, Algeria...
January 22, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28126271/antibody-antibiotic-conjugates-a-novel-therapeutic-platform-against-bacterial-infections
#14
REVIEW
Sanjeev Mariathasan, Man-Wah Tan
Antibodies are potent components of the immune repertoire and have been successfully exploited to treat bacterial infections. Recently an antibody-antibiotic conjugate (AAC) that combines key attributes of an antibody and antibiotic has been shown to be efficacious against Staphylococcus aureus infection. An AAC has three components: an antibiotic payload to kill bacteria, an antibody to target delivery of the payload to bacteria, and a linker attaching the payload to the antibody. With increasing understanding of the biology and pathophysiology of S...
January 23, 2017: Trends in Molecular Medicine
https://www.readbyqxmd.com/read/28125045/single-step-purification-of-monomeric-l-selectin-via-aptamer-affinity-chromatography
#15
Christian Kuehne, Stefanie Wedepohl, Jens Dernedde
l-selectin is a transmembrane receptor expressed on the surface of white blood cells and responsible for the tethering of leukocytes to vascular endothelial cells. This initial intercellular contact is the first step of the complex leukocyte adhesion cascade that ultimately permits extravasation of leukocytes into the surrounding tissue in case of inflammation. Here we show the binding of a soluble histidine tagged l-selectin to a recently described shortened variant of an l-selectin specific DNA aptamer with surface plasmon resonance...
January 24, 2017: Sensors
https://www.readbyqxmd.com/read/28121175/experiences-from-a-support-group-for-families-of-preschool-children-in-the-expressive-aac-user-group
#16
Kristine Stadskleiv
Children using aided language need communication partners who are competent in modeling language, but most parents of children who use AAC will not have extensive experience with aided communication and will therefore need support to become competent language models. In this participatory observational study the experiences of a support group for parents of young children with age-expected language comprehension who use aided communication expressively are outlined. The group was established in 2012 at a habilitation unit in a hospital, and involved five families of children who use AAC...
January 25, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28121173/a-call-for-innovative-social-media-research-in-the-field-of-augmentative-and-alternative-communication
#17
Bronwyn Hemsley, Susan Balandin, Stuart Palmer, Stephen Dann
Augmentative and alternative communication (AAC) social media research is relatively new, and is built on a foundation of research on use of the Internet and social media by people with communication disabilities. Although the field is expanding to include a range of people who use AAC, there are limitations and gaps in research that will need to be addressed in order to keep pace with the rapid evolution of social media connectivity in assistive communication technologies. In this paper, we consider the aims, scope, and methodologies of AAC social media research, with a focus on social network sites...
January 25, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28119178/abdominal-aortic-calcification-on-dual-energy-x-ray-absorptiometry-methods-of-assessment-and-clinical-significance
#18
John T Schousboe, Joshua R Lewis, Douglas P Kiel
Abdominal aortic calcification (AAC) can be accurately recognized on lateral spine images intended for vertebral fracture assessment, that are obtained with dual-energy X-ray absorptiometry (DXA). Greater amounts of AAC are common in the older population for whom DXA is routinely done, and have been consistently associated with incident atherosclerotic cardiovascular disease (ASCVD) events. AAC has also been associated with incident fractures in some prospective studies, but not in others. However, further research is needed to quantify the extent to which measurement of AAC improves prediction of ASCVD events and its impact on physician and patient ASCVD risk management...
January 22, 2017: Bone
https://www.readbyqxmd.com/read/28114681/assessment-with-children-who-need-augmentative-and-alternative-communication-aac-clinical-decisions-of-aac-specialists
#19
Shelley K Lund, Wendy Quach, Kristy Weissling, Miechelle McKelvey, Aimee Dietz
Purpose: The purpose of this study was to explore how speech-language pathologists (SLPs) who are augmentative and alternative communication (AAC) specialists approach the assessment process for 2 case studies, 1 child with cerebral palsy and 1 with autism spectrum disorder. The aim of the study was to answer the following questions: (a) How do clinicians with expertise approach the AAC assessment process for children with developmental disabilities? (b) Can any initial hypothesis be drawn about how SLPs approach the assessment of children with motor versus social interactive deficits? Method: This study used a phenomenological qualitative design...
January 1, 2017: Language, Speech, and Hearing Services in Schools
https://www.readbyqxmd.com/read/28112768/dietary-quality-is-associated-with-abdominal-aortic-calcification-a-mean-of-18-year-longitudinal-study-in-community-dwelling-older-adults
#20
X Shang, D Scott, A Hodge, B Khan, N Khan, D R English, G G Giles, P R Ebeling, K M Sanders
OBJECTIVE: This study aimed to examine the association between baseline and changes in dietary quality assessed by the Alternative Healthy Eating Index-2010 (AHEI-2010) and abdominal aortic calcification (AAC) among community-dwelling older adults. DESIGN: Population-based longitudinal study. SETTING: A subset of the Melbourne Collaborative Cohort Study (MCCS). PARTICIPANTS: 262 community-dwelling adults (60% female) aged 53 ± 5 years at baseline...
2017: Journal of Nutrition, Health & Aging
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