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https://www.readbyqxmd.com/read/28633531/the-effectiveness-of-aided-augmented-input-techniques-for-persons-with-developmental-disabilities-a-systematic-review
#1
Anna A Allen, Ralf W Schlosser, Kristofer L Brock, Howard C Shane
When working with individuals with little or no functional speech, clinicians often recommend that communication partners use the client's augmentative and alternative communication (AAC) device when speaking to the client. This is broadly known as "augmented input" and is thought to enhance the client's learning of language form and content. The purpose of this systematic review was to determine the effects of augmented input on communication outcomes in persons with developmental disabilities and persons with childhood apraxia of speech who use aided AAC...
June 21, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28620888/design-of-isoniazid-smart-nanogel-by-gamma-radiation-induced-template-polymerization-for-biomedical-application
#2
Samia M Omar, Nabila A Maziad, Nourhan M El-Tantawy
PURPOSE: Preparation of Isoniazid (INH) loaded nanogel particles using gamma radiation as safe, simple, cheap and reproducible technique for promoting mycobacterial killing in a lower-dose system aiming in developing of drug resistance. METHODS: Polymeric pH-sensitive nanogels were prepared by gamma radiation-induced polymerization of Acrylic acid (AAc) or Itaconic acid (IA), in aqueous solution of polyvinylpyrrolidone (PVP), as template polymer. The prepared nanogels were utilized for encapsulation of INH...
June 15, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28619611/an-insight-into-selection-specificity-of-quinolone-resistance-determinants-within-enterobacteriaceae-family
#3
Nivedita Dasgupta, Deepjyoti Paul, Debadatta DharChanda, Birson Ingti, Dibyojyoti Bhattacharjee, Atanu Chakravarty, Amitabha Bhattacharjee
OBJECTIVES: Quinolone antimicrobials are frequently misused due to self-medication and suboptimal dose administration, leading to the development of resistance as well as treatment failure. The present study aimed to characterise plasmid-mediated quinolone resistance (PMQR) determinants and their genetic selection in the presence of quinolone stress within members of the Enterobacteriaceae. METHODS: A total of 209 non-duplicate Enterobacteriaceae isolates were collected from hospital and community health centres over the period July 2013 to June 2014...
June 12, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28619137/determinants-of-virulence-and-of-resistance-to-ceftiofur-gentamicin-and-spectinomycin-in-clinical-escherichia-coli-from-broiler-chickens-in-qu%C3%A3-bec-canada
#4
Gabhan Chalmers, Ashley C Cormier, Marie Nadeau, Geneviève Côté, Richard J Reid-Smith, Patrick Boerlin
Antimicrobials are frequently used for the prevention of avian colibacillosis, with gentamicin used for this purpose in Québec until 2003. Ceftiofur was also used similarly, but voluntarily withdrawn in 2005 due to increasing resistance. Spectinomycin-lincomycin was employed as a replacement, but ceftiofur use was partially reinstated in 2007 until its definitive ban by the poultry industry in 2014. Gentamicin resistance frequency increased during the past decade in clinical Escherichia coli isolates from broiler chickens in Québec, despite this antimicrobial no longer being used...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28617614/effects-of-background-color-and-symbol-arrangement-cues-on-construction-of-multi-symbol-messages-by-young-children-without-disabilities-implications-for-aided-aac-design
#5
Jennifer J Thistle, Krista Wilkinson
Children whose speech does not meet their communication needs often benefit from augmentative and alternative communication (AAC). The design of an AAC display may influence the child's ability to communicate effectively. The current study examined how symbol background color cues and symbol arrangement affected construction of multi-symbol messages using line-drawing symbols, by young children with typical development. Participants (N = 52) heard a spoken phrase matching a photograph and selected line drawings within a 4 × 4 array...
June 15, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28617274/supporting-constructed-wetlands-in-p-removal-efficiency-from-surface-water
#6
Agnieszka Bus, Agnieszka Karczmarczyk
The research investigated the implementation of suspended reactive filters to support the phosphorus (P) removal efficiency of constructed wetlands (CWs). The reactive material (RM) used in this study was autoclaved aerated concrete (AAC). The laboratory experiment consists of four plastic boxes filled with the volume of 10 L of artificial P solution with three variants of RM mass to volume ratio: 1:1 (g:L), 5:1 (g:L), 10:1 (g:L), and the blind probe 0:1 (g:L) as a reference. AAC of different weights (10, 50 and 100 g) was wrapped in a filter bag, put into boxes, and suspended...
June 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28614036/an-individualized-approach-to-the-evaluation-of-cushing-syndrome
#7
Susmeeta T Sharma
Cushing syndrome (CS) is caused by chronic exposure to excess glucocorticoids. Early recognition and treatment of hypercortisolemia can lead to decreased morbidity and mortality. The diagnosis of CS and thereafter, establishing the cause can often be difficult, especially in patients with mild and cyclic hypercortisolism. Surgical excision of the cause of excess glucocorticoids is the optimal treatment for CS. Medical therapy (steroidogenesis inhibitors, medications that decrease adrenocorticotropic hormone [ACTH] levels or glucocorticoid antagonists) and pituitary radiotherapy may be needed as adjunctive treatment modalities in patients with residual, recurrent or metastatic disease, in preparation for surgery, or when surgery is contraindicated...
June 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28614035/personalized-care-of-patients-with-adrenocortical-carcinoma-a-comprehensive-approach
#8
Barbra S Miller, Tobias Else
A concerted effort has been made in the past decade to better differentiate benign from malignant adrenocortical tumors. Of those tumors found to be adrenocortical carcinomas (ACCs) and through the use of multiple modalities including biochemical, radiologic, and genomic analysis, significant strides have been made in understanding what drives ACC development, how various treatments may result in different outcomes, which ACCs are more likely to respond to various treatments, and overall prognosis. While most patients will have recurrence of their ACC and succumb to their disease, the disease course is highly variable; it is therefore imperative that each patient is treated with individualized attention paid to their particular ACC...
June 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28612707/genetic-characteristic-of-class-1-integrons-in-proteus-mirabilis-isolates-from-urine-samples
#9
Chih-Ming Chen, Chih-Ho Lai, Hwa-Jene Wu, Lii-Tzu Wu
BACKGROUND: Proteus mirabilis is an opportunistic pathogen, commonly associated with complicated urinary tract infections (UTIs). UTIs caused by multidrug-resistant Proteus mirabilis have increased worldwide. Multidrug-resistance of Gram-negative enteric bacteria is usually associated with class 1 integrons. PURPOSES: To investigate the prevalence and characterize gene cassettes of class 1 integrons in multidrug-resistant P. mirabilis Methods: From 2006 to 2008, 314 P...
June 2017: BioMedicine
https://www.readbyqxmd.com/read/28605961/species-distribution-antibiotic-resistance-and-virulence-traits-in-canine-and-feline-enterococci-in-tunisia
#10
Leila Ben Said, Raoudha Dziri, Nadia Sassi, Carmen Lozano, Karim Ben Slama, Imen Ouzari, Carmen Torres, Naouel Klibi
In order to investigate the possible role of dogs and cats in the carriage and potential dissemination of resistant enterococci, seventy faecal samples from dogs and cats were tested for enterococci. Fifty-eight enterococci were recovered. Isolates were identified as Enterococcus faecium (n = 31) and E. faecalis (n = 14) E. durans (n = 6), E. casseliflavus (n = 2), E. hirae and E. gallinarum (2 isolates each). Enterococcal isolates showed resistance to ciprofloxacin (n = 35), erythromycin (n = 31), tetracycline (n = 25), kanamycin (n = 15), streptomycin (n = 13), pristinamycin (n = 11), gentamicin (n = 10), chloramphenicol (n = 8), and linezolid (n = 6)...
June 2017: Acta Veterinaria Hungarica
https://www.readbyqxmd.com/read/28605936/vascular-disease-and-kidney-stones-abdominal-aortic-calcifications-are-associated-with-low-urine-ph-and-hypocitraturia
#11
Nishant D Patel, Ryan D Ward, Juan Camilo Calle, Eric Remer, Manoj Monga
OBJECTIVE: Vascular calcifications are associated with nephrolithiasis. While studies have demonstrated correlations with vascular disease and calcium stones in kidney stone formers (KSF), an etiologic link has remained elusive. As a non-contrast CT scan (NCCT) is typically part of a stone evaluation, our objective was to evaluate the association of NCCT-based assessment of abdominal aortic calcifications (AAC) with 24-hour urine parameters and stone composition. MATERIALS AND METHODS: 97 KSF were included with CT imaging and 24-hour urine studies...
June 12, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28597688/the-availability-and-accessibility-of-basic-concept-vocabulary-in-aac-software-a-preliminary-study
#12
Jillian H McCarthy, Ilsa Schwarz, Morgan Ashworth
Core vocabulary lists obtained through the analyses of children's utterances include a variety of basic concept words. Supporting young children who use augmentative and alternative communication (AAC) to develop their understanding and use of basic concepts is an area of practice that has important ramifications for successful communication in a classroom environment. This study examined the availability of basic concept words across eight frequently used, commercially available AAC language systems, iPad© applications, and symbol libraries used to create communication boards...
June 9, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28586825/typical-toddlers-participation-in-just-in-time-programming-of-vocabulary-for-visual-scene-display-augmentative-and-alternative-communication-apps-on-mobile-technology-a-descriptive-study
#13
Christine Holyfield, Kathryn Drager, Janice Light, Jessica Gosnell Caron
Purpose: Augmentative and alternative communication (AAC) promotes communicative participation and language development for young children with complex communication needs. However, the motor, linguistic, and cognitive demands of many AAC technologies restrict young children's operational use of and influence over these technologies. The purpose of the current study is to better understand young children's participation in programming vocabulary "just in time" on an AAC application with minimized demands...
June 6, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28585523/fusion-of-p300-and-eye-tracker-data-for-spelling-using-bci2000
#14
Dmitry Kalika, Leslie Collins, Kevin Caves, Chandra Throckmorton
OBJECTIVE: Various augmentative and alternative communication (AAC) devices have been developed in order to aid communication for individuals with communication disorders. Recently, there has been interest in combining EEG data and eye-gaze data with the goal of developing a hybrid (or "fused") BCI (hBCI) AAC system. This work explores the effectiveness of a speller that fuses data from an eye-tracker and the P300 speller in order to create a hybrid P300 speller. APPROACH: This hybrid speller collects both eye-tracking and EEG data in parallel, and the user spells characters on the screen in the same way that they would if they were only using the P300 speller...
June 6, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28577932/in-vitro-activity-of-several-antimicrobial-agents-against-methicillin-resistant-staphylococcus-aureus-mrsa-isolates-expressing-aminoglycoside-modifying-enzymes-potency-of-plazomicin-alone-and-in-combination-with-other-agents
#15
María Carmen López-Díaz, Esther Ríos, Iciar Rodríguez-Avial, Rosa Janneth Simaluiza, Juan José Picazo, Esther Culebras
This study investigated the in-vitro activity of clinically relevant aminoglycosides and new antimicrobial agents - plazomicin, ceftobiprole and dalbavancin - against 55 methicillin-resistant Staphylococcus aureus (MRSA) isolates producing aminoglycoside-modifying enzymes (AMEs). The checkerboard method was used to assess synergism between plazomicin and four antibiotics (fosfomycin, ceftobiprole, cefoxitin and meropenem), and time-kill assays were performed for the most active combinations. Among the aminoglycosides tested, plazomicin was the most active agent against MRSA, with >90% of isolates being inhibited at a minimum inhibitory concentration (MIC) of ≤1 mg/L...
May 31, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28575064/antimicrobial-resistance-of-klebsiella-pneumoniae-stool-isolates-circulating-in-kenya
#16
Chris Rowe Taitt, Tomasz A Leski, Daniel P Erwin, Elizabeth A Odundo, Nancy C Kipkemoi, Janet N Ndonye, Ronald K Kirera, Abigael N Ombogo, Judd L Walson, Patricia B Pavlinac, Christine Hulseberg, Gary J Vora
We sought to determine the genetic and phenotypic antimicrobial resistance (AMR) profiles of commensal Klebsiella spp. circulating in Kenya by testing human stool isolates of 87 K. pneumoniae and three K. oxytoca collected at eight locations. Over one-third of the isolates were resistant to ≥3 categories of antimicrobials and were considered multidrug-resistant (MDR). We then compared the resistance phenotype to the presence/absence of 238 AMR genes determined by a broad-spectrum microarray and PCR. Forty-six genes/gene families were identified conferring resistance to β-lactams (ampC/blaDHA, blaCMY/LAT, blaLEN-1, blaOKP-A/OKP-B1, blaOXA-1-like family, blaOXY-1, blaSHV, blaTEM, blaCTX-M-1 and blaCTX-M-2 families), aminoglycosides (aac(3)-III, aac(6)-Ib, aad(A1/A2), aad(A4), aph(AI), aph3/str(A), aph6/str(B), and rmtB), macrolides (mac(A), mac(B), mph(A)/mph(K)), tetracyclines (tet(A), tet(B), tet(D), tet(G)), ansamycins (arr), phenicols (catA1/cat4, floR, cmlA, cmr), fluoroquinolones (qnrS), quaternary amines (qacEΔ1), streptothricin (sat2), sulfonamides (sul1, sul2, sul3), and diaminopyrimidines (dfrA1, dfrA5, dfrA7, dfrA8, dfrA12, dfrA13/21/22/23 family, dfrA14, dfrA15, dfrA16, dfrA17)...
2017: PloS One
https://www.readbyqxmd.com/read/28567445/unique-features-of-aeromonas-plasmid-pac3-and-expression-of-the-plasmid-mediated-quinolone-resistance-genes
#17
Dae-Wi Kim, Cung Nawl Thawng, Sang Hee Lee, Chang-Jun Cha
A highly fluoroquinolone-resistant isolate of Aeromonas species was isolated from a wastewater treatment plant and found to possess multiple resistance mechanisms, including mutations in gyrA and parC, efflux pumps, and plasmid-mediated quinolone resistance (PMQR) genes. Complete sequencing of the IncU-type plasmid, pAC3, present in the strain revealed a circular plasmid DNA 15,872 bp long containing two PMQR genes [qnrS2 and aac(6')-Ib-cr]. A mobile insertion cassette element containing the qnrS2 gene and a typical miniature inverted-repeat transposable element (MITE) structure was identified in the plasmid...
May 2017: MSphere
https://www.readbyqxmd.com/read/28560738/evaluation-of-ultrasound-reporting-for-thyroid-cancer-diagnosis-and-surveillance
#18
Meghan E Rowe, Marcela Osorio, Ilya Likhterov, Mark L Urken
BACKGROUND: Despite the importance of ultrasound imaging in thyroid disease care, ultrasound reports vary greatly in the features described. It is essential that ultrasound reports contain and present all components necessary for a clinical decision in a reader-friendly format. METHODS: One hundred ninety thyroid and neck ultrasound reports were scored using the universal ultrasound report template developed by Su et al, along with the American Thyroid Association (ATA) and the American Association of Clinical Endocrinologists/Associazione Medici Endocrinologi/European Thyroid Association (AACE/AME/ETA) guidelines...
May 31, 2017: Head & Neck
https://www.readbyqxmd.com/read/28560501/relationship-of-bone-mineral-density-with-valvular-and-annular-calcification-in-community-dwelling-older-people-the-cardiovascular-health-study
#19
Daniele Massera, Shuo Xu, Traci M Bartz, Anna E Bortnick, Joachim H Ix, Michel Chonchol, David S Owens, Eddy Barasch, Julius M Gardin, John S Gottdiener, John R Robbins, David S Siscovick, Jorge R Kizer
Associations between bone mineral density and aortic valvular, aortic annular, and mitral annular calcification were investigated in a cross-sectional analysis of a population-based cohort of 1497 older adults. Although there was no association between continuous bone mineral density and outcomes, a significant association between osteoporosis and aortic valvular calcification in men was found. INTRODUCTION: The process of cardiac calcification bears a resemblance to skeletal bone metabolism and its regulation...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28559654/aortic-arch-calcification-associated-with-cardiovascular-events-and-death-among-patients-with-acute-coronary-syndrome
#20
Tsung-Lin Yang, Chin-Chou Huang, Shao-Sung Huang, Chun-Chih Chiu, Hsin-Bang Leu, Shing-Jong Lin
BACKGROUND: To date, it remains unsettled whether aortic arch calcification (AAC) has prognostic value in patients with acute coronary syndrome. METHODS: From January 1 to December 31, 2013, a total of 225 patients with acute coronary syndrome (mean age 72 ± 26 years, 75% male) were enrolled in this study. Patients admitted to the coronary care unit of a tertiary referral medical center under the preliminary diagnosis of acute coronary syndrome were retrospectively investigated...
May 2017: Acta Cardiologica Sinica
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