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Stem cells chondromalacia

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https://www.readbyqxmd.com/read/23700485/a-novel-biological-approach-to-treat-chondromalacia-patellae
#1
Jaewoo Pak, Jung Hun Lee, Sang Hee Lee
Mesenchymal stem cells from several sources (bone marrow, synovial tissue, cord blood, and adipose tissue) can differentiate into variable parts (bones, cartilage, muscle, and adipose tissue), representing a promising new therapy in regenerative medicine. In animal models, mesenchymal stem cells have been used successfully to regenerate cartilage and bones. However, there have been no follow-up studies on humans treated with adipose-tissue-derived stem cells (ADSCs) for the chondromalacia patellae. To obtain ADSCs, lipoaspirates were obtained from lower abdominal subcutaneous adipose tissue...
2013: PloS One
https://www.readbyqxmd.com/read/21607740/patellar-chondral-defects-a-review-of-a-challenging-entity
#2
REVIEW
George Mouzopoulos, Carlo Borbon, Rainer Siebold
PURPOSE: The aim of this study was to perform a review of the management of patellar cartilage defects, identify prognostic factors for better clinical outcomes, and propose a treatment algorithm of this challenging entity. METHODS: We conducted a review of multiple databases, evaluating the clinical outcomes after patellar cartilage lesion treatment. Because of the heterogeneity of data, a meta-analysis could not be performed. RESULTS: Twelve studies were identified for inclusion...
December 2011: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
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