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Recurrent tract infection in women

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https://www.readbyqxmd.com/read/29341034/therapeutic-assessment-of-vulvar-squamous-intraepithelial-lesions-with-co2-laser-vaporization-in-immunosuppressed-patients
#1
Julisa Chamorro Lascasas Ribalta, Mariana Vendramin Mateussi, Neila Maria de Góis Speck
OBJECTIVE:  A vulvar squamous intraepithelial lesion is deemed to be a preceding lesion to vulvar cancer, especially in women aged under 40 years, holders of an acquired or idiopathic immunosuppression. Several treatments have been used to treat these lesions. One of the aesthetically acceptable therapeutic methods is the CO2 laser vaporization. METHODS:  In a transversal study, 46 records of immunosuppressed women bearing a vulvar low grade and/or high grade squamous intraepithelial lesion were selected out of the retrospective analysis, computing age, date of record, date of vulvar lesion treatment with CO2 laser, the time elapsed between the first and the last visit (in months), the number of visits, the presence or absence of condylomatous lesions in other female lower genital tract sites and whether or not recurrences and persistence of intraepithelial lesions have been noticed during the follow-up...
January 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29324795/nanodiamonds-facilitate-killing-of-intracellular-uropathogenic-e-coli-in-an-in-vitro-model-of-urinary-tract-infection-pathogenesis
#2
Janaki Kannan Iyer, Alexia Dickey, Parvaneh Rouhani, Anil Kaul, Nirmal Govindaraju, Raj Narain Singh, Rashmi Kaul
About 25-44% of women will experience at least one episode of recurrent UTI and the causative agent in over 70% of UTI cases is uropathogenic Escherichia coli (UPEC). UPEC cause recurrent UTI by evading the bladder's innate immune system through internalization into the bladder epithelium where antibiotics cannot reach or be effective. Thus, it is important to develop novel therapeutics to eliminate these intracellular pathogens. Nanodiamonds (NDs) are biocompatible nanomaterials that serve as promising candidates for targeted therapeutic applications...
2018: PloS One
https://www.readbyqxmd.com/read/29306096/embryotoxic-cytokines-potential-roles-in-embryo-loss-and-fetal-programming
#3
REVIEW
Sarah A Robertson, Peck-Yin Chin, Joseph G Femia, Hannah M Brown
Cytokines in the reproductive tract environment at conception mediate a dialogue between the embryo and maternal tissues to profoundly influence embryo development and implantation success. Through effects on gene expression and the cell stress response, cytokines elicit an epigenetic impact with consequences for placental development and fetal growth, which in turn affect metabolic phenotype and long-term health of offspring. There is substantial evidence demonstrating that pro-survival cytokines, such as GM-CSF, CSF1, LIF, HB-EGF and IGFII, support embryos to develop optimally...
December 27, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29277046/the-effect-of-intravesical-instillations-with-hyaluronic-acid-on-sexual-dysfunction-in-women-with-recurrent-urinary-tract-infections-ruti
#4
Gemma Nightingale, Qasem Shehab, Chandrakumaran Kandiah, Lorraine Rush, Clare Rowe-Jones, Christian H Phillips
OBJECTIVE: To determine whether sexual dysfunction in women with recurrent urinary tract infections (RUTI) improved following treatment with intravesical Hyaluronic Acid (HA) instillations. STUDY DESIGN: Ethical approval was obtained for a prospective study to be performed. Patients referred for bladder instillations to treat RUTI, and who were sexually active, were recruited to the study. A selection of validated questionnaires (ICIQ-UI, ICIQ-VS, FSDS-R, ICIQ-FLUTS, O'Leary/Sant and PGI-I) were completed at baseline, three, six and 12 months after initiation of treatment with bladder instillations...
December 15, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29259607/associations-between-viral-infection-history-symptoms-granulocyte-reactive-oxygen-species-activity-and-active-rheumatoid-arthritis-disease-in-untreated-women-at-onset-results-from-a-longitudinal-cohort-study-of-tatarstan-women
#5
Marina I Arleevskaya, Albina Z Shafigullina, Yulia V Filina, Julie Lemerle, Yves Renaudineau
To evaluate the effects of infectious episodes at early stages of rheumatoid arthritis (eRA) development, 59 untreated eRA patients, 77 first-degree relatives, from a longitudinal Tatarstan women cohort, were included, and compared to 67 healthy women without rheumatoid arthritis (RA) in their family history. At inclusion, informations were collected regarding both the type and incidence of infectious symptom episodes in the preceding year, and granulocyte reactive oxygen species (ROS) were studied at the basal level and after stimulation with serum-treated zymosan (STZ)...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29258889/association-of-escherichia-coli-st131-lineage-with-risk-of-urinary-tract-infection-recurrence-among-young-women
#6
Miriam D Ismail, Ihsan Ali, Savannah Hatt, Elizabeth A Salzman, Anna W Cronenwett, Carl F Marrs, Alexander H Rickard, Betsy Foxman
OBJECTIVES: Test the hypothesis that urinary tract infections (UTI) caused by Escherichia coli of the ST131 lineage are more likely to recur than UTI cause by other E. coli lineages. METHODS: We used isolates from 221 young women with UTI caused by Escherichia coli participating in a randomized controlled trial. Participants were followed for 6 months or until recurrence. RESULTS: Sequence type was not associated with risk of recurrence. Isolates in the ST131 lineage were more resistant to quinolones (6% vs 1%) than other STs, but not trimethoprim sulfamethoxazole (15% vs 15%)...
December 16, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/29241191/evaluation-of-behavioral-and-susceptibility-patterns-in-premenopausal-women-with-recurrent-urinary-tract-infections-a-case-control-study
#7
Saddam Al Demour, Mera A Ababneh
Recurrent urinary tract infections (UTI) are a major source of morbidity and healthcare costs. Risk factors associated with recurrence rates in premenopausal women can be attributed to patient lifestyle behavior. The aim of this study was to assess hygienic risk factors, determine pathogen distribution, and susceptibility patterns in premenopausal women with recurrent UTI. This was case-control study in which a face-to-face interview was conducted to obtain information from premenopausal women with recurrent UTI...
December 14, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29196069/impact-of-allergy-and-resistance-on-antibiotic-selection-for-recurrent-urinary-tract-infections-in-older-women
#8
Rena D Malik, Yuefeng Rose Wu, Alana L Christie, Feras Alhalabi, Philippe E Zimmern
OBJECTIVES: To review the impact of antibiotic allergy and resistance in older women with recurrent urinary tract infections (RUTIs) as determinants for a suitable oral antibiotic treatment choice. METHODS: A prospectively maintained database of women 65 years old and older with documented RUTIs (≥3 UTI/y) and trigonitis on cystoscopy was reviewed. Demographic data, known drug allergies, renal function, antibiotic susceptibility of most recent urine culture, allergy, or resistance to trimethoprim-sulfamethoxazole (TMP-SMX), fluoroquinolones, and nitrofurantoin were obtained...
November 28, 2017: Urology
https://www.readbyqxmd.com/read/29184412/a-6-year-study-of-complicated-urinary-tract-infections-in-southern-china-prevalence-antibiotic-resistance-clinical-and-economic-outcomes
#9
Xiaoyan Li, Yunqin Chen, Weiguo Gao, Hao Ye, Zhongchao Shen, Zehuai Wen, Jia Wei
Urinary tract infections (UTIs) are common nosocomial infections. This study evaluated the prevalence, pathogens, antibiotic resistances, clinical outcomes, and hospitalization costs associated with complicated UTIs in southern China, and risk factors delaying patient discharge. We retrospectively reviewed electronic medical records of 4,284 (61.4% women) complicated UTI-related hospitalizations from 2008 to 2013. Average patient age was 61.1 years and median hospital stay was 11 days. Pathogens were isolated from 1,071 urine and 148 blood specimens...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29181550/intravesical-hyaluronic-acid-and-chondroitin-sulfate-for-recurrent-urinary-tract-infections-systematic-review-and-meta-analysis
#10
Jonathan Charles Goddard, Dick A W Janssen
INTRODUCTION AND HYPOTHESIS: The objective was to assess the efficacy of intravesical hyaluronic acid (HA) and chondroitin sulfate (CS), alone or in combination, for recurrent urinary tract infections (RUTIs) in adult female patients using a systematic review and meta-analysis. METHODS: English-language articles were obtained from the MEDLINE, Embase, and Cochrane databases through November 2016, by manual searching and cross-referencing. Randomized and nonrandomized trials of adult female patients with a documented history of RUTIs who received HA, CS or HA plus CS were included...
November 27, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29171130/first-experience-in-the-uk-of-treating-women-with-recurrent-urinary-tract-infections-with-the-bacterial-vaccine-uromune-%C3%A2
#11
Bob Yang, Stephen Foley
OBJECTIVES: To determine the effectiveness of Uromune(®) in preventing recurrent urinary tract infections (UTIs) in women. PATIENTS AND METHODS: A total of 77 women with microbiology-proven recurrent UTIs were given Uromune sublingual vaccine for a period of 3 months. Time to first UTI recurrence since treatment and adverse events were prospectively recorded in a follow-up period of up to 12 months. RESULTS: Of the 77 women, 75 completed the treatment...
November 23, 2017: BJU International
https://www.readbyqxmd.com/read/29170359/non-antibiotic-options-for-recurrent-urinary-tract-infections-in-women
#12
Jonathan Barclay, Rajan Veeratterapillay, Chris Harding
No abstract text is available yet for this article.
November 23, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29135809/definition-of-recurrent-urinary-tract-infections-in-women-which-one-to-adopt
#13
Rena D Malik, Yuefeng Rose Wu, Philippe E Zimmern
OBJECTIVES: The aim of this study was to systematically review the various definitions of recurrent urinary tract infection (RUTI) recommended by experts and specialty societies cited in biomedical literature. METHODS: A systematic review of RUTI in women was conducted using MEDLINE, EMBASE, and PubMed between 1966 and 2016 according to the Preferred Reporting Items for Systematic Review and Meta-Analyses Statement. Twenty-five publications were selected for inclusion in this analysis...
November 13, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29111902/the-effect-of-cranberry-juice-consumption-on-the-recurrence-of-urinary-tract-infection-relationship-to-baseline-risk-factors
#14
Kevin C Maki, Kristin M Nieman, Arianne L Schild, Kerrie L Kaspar, Christina Khoo
OBJECTIVE: The objective of this study was to assess relationships between clinical predictors of urinary tract infection (UTI) and effects of cranberry juice consumption on recurrence in a post hoc analysis of a 24-week, randomized, double-blind, placebo-controlled, multicenter clinical trial in women with a recent history of UTI. METHODS: Participants consumed a cranberry (n = 185) or placebo (n = 188) beverage (240 mL) daily. Odds ratios (OR) from 20 candidate predictor variables were evaluated in univariate analyses to assess clinical UTI incidence relationships in the placebo group...
November 7, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29077711/prenatal-vitamin-d-supplementation-reduces-risk-of-asthma-recurrent-wheeze-in-early-childhood-a-combined-analysis-of-two-randomized-controlled-trials
#15
Helene M Wolsk, Bo L Chawes, Augusto A Litonjua, Bruce W Hollis, Johannes Waage, Jakob Stokholm, Klaus Bønnelykke, Hans Bisgaard, Scott T Weiss
BACKGROUND: We recently published two independent randomized controlled trials of vitamin D supplementation during pregnancy, both indicating a >20% reduced risk of asthma/recurrent wheeze in the offspring by 3 years of age. However, neither reached statistical significance. OBJECTIVE: To perform a combined analysis of the two trials and investigate whether maternal 25-hydroxy-vitamin D (25(OH)D) level at trial entry modified the intervention effect. METHODS: VDAART (N = 806) and COPSAC2010...
2017: PloS One
https://www.readbyqxmd.com/read/29077290/-effectiveness-of-a-home-hospitalization-program-for-patients-with-urinary-tract-infection-after-discharge-from-an-emergency-department
#16
María Soledad Gallardo, Ane Antón, Esther Pulido Herrero, Miren Itziar Larruscain, Rocío Guinea Suárez, Susana García Gutiérrez, Julio César Sandoval Negral
OBJECTIVES: To compare outcomes of urinary tract infections (UTIs) in patients referred to a home hospitalization program or admitted to a conventional ward after initial management in the emergency department. MATERIAL AND METHODS: Prospective, quasi-experimental study of patients with UTIs attended in 3 hospital emergency departments in the public health system of the Basque Country, Spain, between January 2012 and June 2013. Patients were assigned to 2 groups according to site of treatment (home or hospital ward) after discharge from the emergency department...
October 2017: Emergencias: Revista de la Sociedad Española de Medicina de Emergencias
https://www.readbyqxmd.com/read/29063878/recurrent-urinary-tract-infections-in-women-how-promising-is-the-use-of-probiotics
#17
REVIEW
Varsha Gupta, Deepika Nag, Pratibha Garg
Urinary tract infections (UTIs) currently rank amongst the most prevalent bacterial infections, representing a major health hazard. UTIs in females usually start as vaginal infections and ascend to the urethra and bladder. Recurrent UTIs (rUTIs) can be defined as at least three episodes of UTI in 1 year or two episodes in 6 months. Various antibiotics have been the mainstay of therapy in ameliorating the incidence of UTIs, but recurrent infections continue to afflict many women. It necessitates the exploitation of alternative antimicrobial therapy...
July 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29054298/antimicrobial-resistance-in-community-acquired-urinary-tract-infections-in-paris-in-2015
#18
D Chervet, O Lortholary, J-R Zahar, A Dufougeray, B Pilmis, H Partouche
BACKGROUND: Urinary tract infection (UTI) is one of the most frequent community-acquired infection. Escherichia coli resistance has been on the rise since 2000s. METHODS: We conducted a prospective multicenter cohort study including adults who had a positive urine cytobacteriological examination (UCBE) performed in our Parisian suburb laboratory platform from October 2014 to March 2015. RESULTS: A total of 1223 patients were included: 995 (81...
October 17, 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/29046404/cranberry-reduces-the-risk-of-urinary-tract-infection-recurrence-in-otherwise-healthy-women-a-systematic-review-and-meta-analysis
#19
REVIEW
Zhuxuan Fu, DeAnn Liska, David Talan, Mei Chung
Background: Cranberry (Vaccinium spp.) has been advocated for treatment of urinary tract infection (UTI); however, its efficacy is controversial. Women have a 50% risk of UTI over their lifetime, and ∼20-30% experience a subsequent UTI recurrence.Objective: We conducted this meta-analysis to assess the effect of cranberry on the risk of UTI recurrence in otherwise healthy women.Methods: Literature published before January 2011 was obtained from 2 published systematic reviews, and we conducted updated searches in EMBASE and MEDLINE (through July 2017)...
December 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/29042485/maternal-stress-during-pregnancy-and-allergic-diseases-in-children-during-the-first-year-of-life
#20
Katarzyna Smejda, Kinga Polanska, Dorota Merecz-Kot, Anna Krol, Wojciech Hanke, Joanna Jerzynska, Wlodzimierz Stelmach, Paweł Majak, Iwona Stelmach
BACKGROUND: Many recent studies indicate that prenatal maternal distress increases the risk of allergic diseases in children. The mechanisms that favor it are still unclear. OBJECTIVES: We aimed to assess the association between exposure to different kinds of prenatal stress and the occurrence of atopic dermatitis, food allergy, wheezing, and recurrent respiratory tract infections in children. METHODS: The study population consisted of 370 mother-child pairs from a Polish Mother and Child Cohort (REPRO_PL)...
October 17, 2017: Respiratory Care
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