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https://www.readbyqxmd.com/read/29782670/surface-enhanced-chiroptical-spectroscopy-with-superchiral-surface-waves
#1
Giovanni Pellegrini, Marco Finazzi, Michele Celebrano, Lamberto Duò, Paolo Biagioni
No abstract text is available yet for this article.
May 21, 2018: Chirality
https://www.readbyqxmd.com/read/29779169/-keeping-in-mind-the-gender-stereotype-the-role-of-need-for-closure-in-the-retrieval-induced-forgetting-of-female-managers-qualities
#2
Gennaro Pica, Antonio Pierro, Valerio Pellegrini, Valeria De Cristofaro, Annamaria Giannini, Arie W Kruglanski
The present research addressed the question of whether need for closure (NFC; Kruglanski in The psychology of closed mindedness, Psychology Press, New York, 2004) biases individuals' memory of female leaders. Merging research on role congruity theory of leadership (Koenig et al. in Psychol Bull 4:616-642, 2011. https://doi.org/10.1037/a0023557 ) and research on retrieval-induced forgetting (RIF, Anderson et al. in J Exp Psychol Learn Mem Cognit 20:1063-1087, 1994. https://doi.org/10.1037/0022-3514.65.5.861 ), we hypothesized and found that high-NFC participants show (1) a higher RIF of dimensions commonly associated with the leadership prototype (agentic/masculine) ascribed to female manager targets, when selectively retrieved dimensions commonly associated with the female prototype (communal/feminine) were ascribed to the same target; and (2) a lessened RIF of female stereotypical dimensions ascribed to female manager targets, when selectively retrieved prototypical leadership dimensions were ascribed to the same target...
May 19, 2018: Cognitive Processing
https://www.readbyqxmd.com/read/29777632/predictor-factors-for-long-term-outcomes-stability-of-coronally-advanced-flap-with-or-without-connective-tissue-graft-in-the-treatment-of-single-maxillary-gingival-recessions-9-years-results-of-a-randomised-controlled-clinical-trial
#3
Giulio Rasperini, Raffaele Acunzo, Gaia Pellegrini, Giorgio Pagni, Maurizio Tonetti, Giovan Paolo Pini Prato, Pierpaolo Cortellini
AIM: To assess the clinical outcomes 9 years after the surgical treatment of single maxillary gingival recessions and identify predictors for long-term gingival margin stability. MATERIALS AND METHODS: Twenty-five gingival recession (Miller Class I and II) were randomly treated with CAF plus CTG or CAF alone. Outcomes included Complete Root Coverage (CRC), Recession Reduction (REC), Keratinized Tissue (KT) gain and dentin hypersensitivity, and were evaluated at 6-month, 1-year and 9-year...
May 19, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29770143/a-census-of-tandemly-repeated-polymorphic-loci-in-genic-regions-through-the-comparative-integration-of-human-genome-assemblies
#4
Loredana M Genovese, Filippo Geraci, Lucia Corrado, Eleonora Mangano, Romina D'Aurizio, Roberta Bordoni, Marco Severgnini, Giovanni Manzini, Gianluca De Bellis, Sandra D'Alfonso, Marco Pellegrini
Polymorphic Tandem Repeat (PTR) is a common form of polymorphism in the human genome. A PTR consists in a variation found in an individual (or in a population) of the number of repeating units of a Tandem Repeat (TR) locus of the genome with respect to the reference genome. Several phenotypic traits and diseases have been discovered to be strongly associated with or caused by specific PTR loci. PTR are further distinguished in two main classes: Short Tandem Repeats (STR) when the repeating unit has size up to 6 base pairs, and Variable Number Tandem Repeats (VNTR) for repeating units of size above 6 base pairs...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29768281/ultrasound-cyclo-plasty-in-patients-with-glaucoma-1-year-results-from-a-multicentre-prospective-study
#5
Giuseppe Giannaccare, Aldo Vagge, Stefano Sebastiani, Lara E Urbini, Paolo Corazza, Marco Pellegrini, Luciana Carmassi, Fulvio Bergamini, Carlo E Traverso, Emilio C Campos
PURPOSE: The aim of this study was to evaluate the safety and efficacy of ultrasound cyclo-plasty (UCP) for reducing intraocular pressure (IOP) in patients with glaucoma. METHODS: This is a multicentre prospective study conducted in 3 Italian glaucoma centres. UCP was performed by EyeOP1, which delivers ultrasound beams using 6 piezoelectric transducers activated for 4/6 s (first generation) or 8 s (second generation). Primary outcomes were the mean IOP reduction and the rates of success after 1 year...
May 16, 2018: Ophthalmic Research
https://www.readbyqxmd.com/read/29742391/loss-of-mecp2-leads-to-activation-of-p53-and-neuronal-senescence
#6
Minori Ohashi, Elena Korsakova, Denise Allen, Peiyee Lee, Kai Fu, Benni S Vargas, Jessica Cinkornpumin, Carlos Salas, Jenny C Park, Igal Germanguz, Justin Langerman, Contantinos Chronis, Edward Kuoy, Stephen Tran, Xinshu Xiao, Matteo Pellegrini, Kathrin Plath, William E Lowry
To determine the role for mutations of MECP2 in Rett syndrome, we generated isogenic lines of human induced pluripotent stem cells, neural progenitor cells, and neurons from patient fibroblasts with and without MECP2 expression in an attempt to recapitulate disease phenotypes in vitro. Molecular profiling uncovered neuronal-specific gene expression changes, including induction of a senescence-associated secretory phenotype (SASP) program. Patient-derived neurons made without MECP2 showed signs of stress, including induction of P53, and senescence...
May 8, 2018: Stem Cell Reports
https://www.readbyqxmd.com/read/29739328/a-novel-ultrafast-low-dose-computed-tomography-protocol-allows-concomitant-coronary-artery-evaluation-and-lung-cancer-screening
#7
Carlo Gaudio, Gennaro Petriello, Francesco Pelliccia, Alessandra Tanzilli, Alberto Bandiera, Gaetano Tanzilli, Francesco Barillà, Vincenzo Paravati, Massimo Pellegrini, Enrico Mangieri, Paolo Barillari
BACKGROUND: Cardiac computed tomography (CT) is often performed in patients who are at high risk for lung cancer in whom screening is currently recommended. We tested diagnostic ability and radiation exposure of a novel ultra-low-dose CT protocol that allows concomitant coronary artery evaluation and lung screening. METHODS: We studied 30 current or former heavy smoker subjects with suspected or known coronary artery disease who underwent CT assessment of both coronary arteries and thoracic area (Revolution CT, General Electric)...
May 8, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29737150/pycnogenol%C3%A2-supplementation-improves-the-control-of-irritable-bowel-syndrome-symptoms
#8
Gianni Belcaro, Giuseppe Gizzi, Luciano Pellegrini, Beatrice Feragalli, Roberto Cotellese, Marisa Cacchio, Marcello Corsi
BACKGROUND: The aim of this registry was to evaluate the effects of Pycnogenol® on the main symptoms of irritable bowel syndrome (IBS) in otherwise healthy individuals. METHODS: This study included 77 healthy individuals with symptoms of IBS. The patients were divided into three groups: group 1 was treated with Buscopan (10 mg when needed), group 2 (Antispasmina col forte; 50 mg papaverine hydrochloride+10 mg belladonna extract when needed) and 3 (Pycnogenol® 150 mg/day) for 3 weeks...
June 2018: Panminerva Medica
https://www.readbyqxmd.com/read/29730330/water-based-aerobic-training-improves-strength-parameters-and-cardiorespiratory-outcomes-in-elderly-women
#9
Rochelle Rocha Costa, Ana Carolina Kanitz, Thais Reichert, Alexandre Konig Garcia Prado, Leandro Coconcelli, Adriana Cristine Koch Buttelli, Laura Frances Pereira, Marcos Paulo Bienert Masiero, Andressa Pellegrini Meinerz, Matheus Oliveira Conceição, Isadora Loch Sbeghen, Luiz Fernando Martins Kruel
The aim of the present study was to compare the effects of water-based aerobic training and water-based resistance training on muscular strength and cardiorespiratory fitness in older women. Sixty-nine individuals were randomized into the following three groups: the water-based aerobic training (WA, n = 23) group, the water-based resistance training (WR, n = 23) group, and the control group (CG, n = 23). Participants were trained two times per week for 10 weeks. The trainings presented a linear periodization with an increase in the volume-intensity relation...
May 3, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29719051/preliminary-approach-for-the-surface-electromyographical-evaluation-of-the-oral-phase-of-swallowing
#10
C Dellavia, R Rosati, F Musto, G Pellegrini, G Begnoni, V F Ferrario
BACKGROUND: Swallowing is a muscular activity that occurs both after mastication and spontaneously as a result of saliva accumulation. Spontaneous saliva swallowing occurs about every 2 min. Comprehension of its functional mechanisms is relevant to assess their modification in clinical situations. A standardized surface electromyographical (ssEMG) protocol for the evaluation of this muscle activity is lacking. OBJECTIVES: i)to determine the reproducibility of a ssEMG protocol for the evaluation of the oral phase of saliva swallowing, ii)to evaluate the activity of masseter(MM), anterior temporalis(TA), submental muscles(SM) to draw a reference model of swallowing...
May 2, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29700325/kh176-safeguards-mitochondrial-diseased-cells-from-redox-stress-induced-cell-death-by-interacting-with-the-thioredoxin-system-peroxiredoxin-enzyme-machinery
#11
Julien Beyrath, Mina Pellegrini, Herma Renkema, Lisanne Houben, Svetlana Pecheritsyna, Peter van Zandvoort, Petra van den Broek, Akkiz Bekel, Pierre Eftekhari, Jan A M Smeitink
A deficient activity of one or more of the mitochondrial oxidative phosphorylation (OXPHOS) enzyme complexes leads to devastating diseases, with high unmet medical needs. Mitochondria, and more specifically the OXPHOS system, are the main cellular production sites of Reactive Oxygen Species (ROS). Increased ROS production, ultimately leading to irreversible oxidative damage of macromolecules or to more selective and reversible redox modulation of cell signalling, is a causative hallmark of mitochondrial diseases...
April 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29699866/effects-of-practice-on-visual-finger-force-control-in-children-at-risk-of-developmental-coordination-disorder
#12
Maria Angélica da Rocha Diz, Marcela de Castro Ferracioli, Cynthia Yukiko Hiraga, Marcio Alves de Oliveira, Ana Maria Pellegrini
BACKGROUND: The production of finger force control is essential for a large number of daily activities. There is evidence that deficits in the mechanisms of accuracy and control of finger force tasks are associated with children's motor difficulties. OBJECTIVE: To compare the effect of practice of an isometric finger force/torque task between children with significant movement difficulty and those with no difficulty movement. METHODS: Twenty-four children aged between 9 and 10 years (12 at risk of developmental coordination disorder and 12 with no movement difficulty - typically developing children) were asked to produce finger force/torque control in a continuous and constant 25% of maximum voluntary torque with visual feedback during 15s...
April 14, 2018: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/29691797/designing-a-score-based-method-for-the-evaluation-of-the-nutritional-quality-of-the-gluten-free-bakery-products-and-their-gluten-containing-counterparts
#13
Federico Morreale, Donato Angelino, Nicoletta Pellegrini
Gluten-free (GF) products are consumed both by individuals with celiac disease and by an increasing number of people with no specific medical needs. Although the technological quality of GF products has been recently improved, their nutritional quality is still scarcely addressed. Moreover, the few published studies report conflicting results, mostly because the information from product nutrition facts is the only considered factor. The aim of the present study was to develop a score-based method for the nutritional evaluation of 134 packaged Italian GF bakery products and to compare it with that of 162 matched gluten-containing (GC) food items...
April 25, 2018: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/29691298/enhanced-therapeutic-activity-of-non-internalizing-small-molecule-drug-conjugates-targeting-carbonic-anhydrase-ix-in-combination-with-targeted-interleukin-2
#14
Samuele Cazzamalli, Barbara Ziffels, Fontaine Widmayer, Patrizia Murer, Giovanni Pellegrini, Francesca Pretto, Sarah Wulhfard, Dario Neri
PURPOSE: Antibody-drug conjugates and small molecule-drug conjugates have been proposed as alternatives to conventional anti-cancer cytotoxic agents, with the potential to deliver bioactive payloads to the site of disease, helping spare normal tissues. Experimental Design: Here we describe a novel small molecule-drug conjugate, based on a high-affinity ligand specific to carbonic anhydrase IX. The product featured a peptidic linker, suitable for cleavage in the tumor extracellular environment, and monomethyl auristatin E as cytotoxic payload...
April 24, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29691232/topological-arrangement-of-cardiac-fibroblasts-regulates-cellular-plasticity
#15
Jingyi Yu, Marcus M Seldin, Kai Fu, Shen Li, Larry Lam, Ping Wang, Yijie Wang, Dian Huang, Thang L Nguyen, Bowen Wei, Rajan P Kulkarni, Dino Di Carlo, Michael Teitell, Matteo Pellegrini, Aldons J Lusis, Arjun Deb
<u>Rationale:</u> Cardiac fibroblasts do not form a syncytium but reside in the interstitium between myocytes. This topological relationship between fibroblasts and myocytes is maintained throughout post-natal life until acute myocardial injury occurs, when fibroblasts are recruited to, proliferate and aggregate in the region of myocyte necrosis. The accumulation or aggregation of fibroblasts in the area of injury thus represents a unique event in the life cycle of the fibroblast but little is known about how changes in the topological arrangement of fibroblasts following cardiac injury affect fibroblast function...
April 24, 2018: Circulation Research
https://www.readbyqxmd.com/read/29690398/revisiting-the-disjunct-distribution-of-conopleura-hinds-1844-mollusca-gastropoda-drilliidae
#16
Andrea Nappo, Xabier Rey, Daniel Pellegrini, Giuseppe Bonomolo, Fabio Crocetta
The family Drilliidae includes approximately 30 genera and 500 recent species. Among them, the genus Conopleura includes three recent species and shows a disjunct distribution in the central Indo-Pacific and the temperate northern Atlantic (Mediterranean Sea). Here, we review the genus, redescribe it, and investigate the validity of its accepted taxa by shell morphology and geometric morphometry. Conopleura striata and C. latiaxisa are considered as valid species. Their distribution has been enlarged to Taiwan and India for C...
March 11, 2018: Zootaxa
https://www.readbyqxmd.com/read/29674440/lenalidomide-in-pretreated-mantle-cell-lymphoma-patients-an-italian-observational-multicenter-retrospective-study-in-daily-clinical-practice-the-lenamant-study
#17
Vittorio Stefoni, Cinzia Pellegrini, Alessandro Broccoli, Luca Baldini, Monica Tani, Emanuele Cencini, Amalia Figuera, Michela Ansuinelli, Elisa Bernocco, Maria Cantonetti, Maria Christina Cox, Filippo Ballerini, Chiara Rusconi, Carlo Visco, Luca Arcaini, Angelo Fama, Roberto Marasca, Stefano Volpetti, Alessia Castellino, Catello Califano, Marina Cavaliere, Guido Gini, Anna Marina Liberati, Gerardo Musuraca, Anna Lucania, Giuseppina Ricciuti, Lisa Argnani, Pier Luigi Zinzani
BACKGROUND: Mantle cell lymphoma (MCL) has the worst prognosis of B-cell subtypes owing to its aggressive clinical disease course and incurability with standard chemo-immunotherapy. Options for relapsed MCL are limited, although several single agents have been studied. Lenalidomide is available in Italy for patients with MCL based on a local disposition of the Italian Drug Agency. SUBJECTS, MATERIALS, AND METHODS: An observational retrospective study was conducted in 24 Italian hematology centers with the aim to improve information on effectiveness and safety of lenalidomide use in real practice...
April 19, 2018: Oncologist
https://www.readbyqxmd.com/read/29669664/evaluating-children-with-suspected-allergic-reactions-to-vaccines-for-infectious-diseases
#18
Fabrizio Franceschini, Paolo Bottau, Silvia Caimmi, Fabio Cardinale, Giuseppe Crisafulli, Lucia Liotti, Guido Pellegrini, Diego Peroni, Francesca Saretta, Carla Mastrorilli, Carlo Caffarelli
BACKGROUND: Vaccines often contain potentially allergenic material in addition to pathogen-specific immunogens that may induce allergic reactions. Parents and physicians often suspect that adverse reactions to vaccines are allergic in etiology. The concern that some of the substances contained in vaccines may trigger an anaphylactic reaction may lead to a low vaccination adherence with emergence of infectious disease epidemics. OBJECTIVE: To provide practical suggestions for managing children suspected to have an allergic reaction to a vaccine...
May 1, 2018: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/29658029/in-vitro-lipid-digestion-in-raw-and-roasted-hazelnut-particles-and-oil-bodies
#19
Edoardo Capuano, Nicoletta Pellegrini, Eleni Ntone, Constantinos V Nikiforidis
Previous studies have proved that the physical encapsulation of nutrients by the cell walls of plant foods modulates macronutrient bioaccessibility during human digestion. In this study, we investigated structural factors that modulate lipid hydrolysis during in vitro digestion of raw and roasted hazelnut particles and isolated oil bodies. Isolated oil bodies exhibited a significantly higher lipid hydrolysis compared to hazelnut particles. Moreover, roasting had an impact on the structure of hazelnut cell walls implying a more efficient diffusion of digestive fluids and enzymes into the hazelnut cells...
April 16, 2018: Food & Function
https://www.readbyqxmd.com/read/29657586/european-heart-rhythm-association-ehra-heart-rhythm-society-hrs-asia-pacific-heart-rhythm-society-aphrs-latin-american-heart-rhythm-society-lahrs-expert-consensus-on-arrhythmias-and-cognitive-function-what-is-the-best-practice
#20
Nikolaos Dagres, Tze-Fan Chao, Guilherme Fenelon, Luis Aguinaga, Daniel Benhayon, Emelia J Benjamin, T Jared Bunch, Lin Yee Chen, Shih-Ann Chen, Francisco Darrieux, Angelo de Paola, Laurent Fauchier, Andreas Goette, Jonathan Kalman, Lalit Kalra, Young-Hoon Kim, Deirdre A Lane, Gregory Y H Lip, Steven A Lubitz, Manlio F Márquez, Tatjana Potpara, Domingo Luis Pozzer, Jeremy N Ruskin, Irina Savelieva, Wee Siong Teo, Hung-Fat Tse, Atul Verma, Shu Zhang, Mina K Chung, William-Fernando Bautista-Vargas, Chern-En Chiang, Alejandro Cuesta, Gheorghe-Andrei Dan, David S Frankel, Yutao Guo, Robert Hatala, Young Soo Lee, Yuji Murakawa, Cara N Pellegrini, Claudio Pinho, David J Milan, Daniel P Morin, Elenir Nadalin, George Ntaios, Mukund A Prabhu, Marco Proietti, Lena Rivard, Mariana Valentino, Alena Shantsila
No abstract text is available yet for this article.
April 2018: Journal of Arrhythmia
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