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https://www.readbyqxmd.com/read/28230812/urban-pollutant-transport-and-infiltration-into-buildings-using-perfluorocarbon-tracers
#1
James C Matthews, Asan Bacak, M Anwar H Khan, Matthew D Wright, Michael Priestley, Damien Martin, Carl J Percival, Dudley E Shallcross
People spend the majority of their time indoors and therefore the quality of indoor air is worthy of investigation; indoor air quality is affected by indoor sources of pollutants and from pollutants entering buildings from outdoors. In this study, unique perfluorocarbon tracers were released in five experiments at a 100 m and ~2 km distance from a large university building in Manchester, UK and tracer was also released inside the building to measure the amount of outdoor material penetrating into buildings and the flow of material within the building itself...
February 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28229034/comprehensive-review-of-non-operative-management-of-hallux-rigidus
#2
REVIEW
Charles Kon Kam King, James Loh Sy, Qishi Zheng, Kinjal V Mehta
This article aims to provide an evidence-based literature review for the non-operative management of hallux rigidus. Currently, there is very little article on the evidence for the non-operative management of hallux rigidus. A comprehensive evidence-based literature review of the PubMed database conducted in November 2016, identified 11 relevant articles out of 560 articles assessing the efficacy of non-operative modalities for hallux rigidus. The 11 studies were then assigned to a level of evidence (I-IV)...
January 20, 2017: Curēus
https://www.readbyqxmd.com/read/28228852/3d-printed-fluidics-with-embedded-analytic-functionality-for-automated-reaction-optimisation
#3
Andrew J Capel, Andrew Wright, Matthew J Harding, George W Weaver, Yuqi Li, Russell A Harris, Steve Edmondson, Ruth D Goodridge, Steven D R Christie
Additive manufacturing or '3D printing' is being developed as a novel manufacturing process for the production of bespoke micro- and milliscale fluidic devices. When coupled with online monitoring and optimisation software, this offers an advanced, customised method for performing automated chemical synthesis. This paper reports the use of two additive manufacturing processes, stereolithography and selective laser melting, to create multifunctional fluidic devices with embedded reaction monitoring capability...
2017: Beilstein Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28227939/effects-of-coplanar-shielding-for-high-field-mri
#4
Joseph V Rispoli, Matthew D Wilcox, Samantha By, Steven M Wright, Mary P McDougall, Joseph V Rispoli, Matthew D Wilcox, Samantha By, Steven M Wright, Mary P McDougall, Matthew D Wilcox, Steven M Wright, Samantha By, Mary P McDougall, Joseph V Rispoli
This work investigates the efficacy of "coplanar shielding," in which copper shields are oriented concentric and coplanar to the RF coils rather than implemented as a full ground plane behind them. Following FDTD simulations to determine optimal shielding parameters, two coil geometries were constructed: a circular loop surface coil and a half-volume five-element receive array. Each was evaluated using bench measurements with and without coplanar shielding. Imaging, including accelerated SENSE imaging, was performed with the shielded and unshielded receive arrays on a whole-body 7T scanner...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227709/bayesian-gaussian-processes-for-identifying-the-deteriorating-patient
#5
Glen Wright Colopy, Marco A F Pimentel, Stephen J Roberts, David A Clifton, Glen Wright Colopy, Marco A F Pimentel, Stephen J Roberts, David A Clifton, Glen Wright Colopy, Marco A F Pimentel, Stephen J Roberts, David A Clifton
The step-down unit (SDU) is a high-acuity hospital environment, to which patients may be sent after discharge from the intensive care unit (ICU). About 1- in-7 patients will deteriorate in the SDU and require emergency readmission to the ICU. Upon readmission, these patients experience significantly higher mortality risks and lengths of stay. Gaussian process regression (GPR) models are proposed as a flexible, principled, probabilistic method to address the clinical need to monitor continuously patient time-series of vital signs acquired in the SDU...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226593/dynamic-cerebral-autoregulation-in-young-athletes-following-concussion
#6
Kyriaki Kostoglou, Alexander D Wright, Jonathan D Smirl, Kelsey Bryk, Paul van Donkelaar, Georgios D Mitsis, Kyriaki Kostoglou, Alexander D Wright, Jonathan D Smirl, Kelsey Bryk, Paul van Donkelaar, Georgios D Mitsis, Paul van Donkelaar, Alexander D Wright, Kyriaki Kostoglou, Jonathan D Smirl, Kelsey Bryk, Georgios D Mitsis
The purpose of this study was to examine cerebral autoregulation (CA) in young athletes experiencing concussion. The subjects were monitored and repeatedly tested 72 hours, 2 weeks and 1 month post-injury. Mean arterial blood pressure (MABP), end-tidal partial pressure of carbon dioxide (PETCO2) and cerebral blood flow velocity (CBFV) in the middle and posterior cerebral arteries were monitored during mental activation paradigms. In order to characterize CA we employed autoregressive models with exogenous inputs (ARX) and impulse response models based on the Laguerre expansion technique (LET)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225656/school-nurse-evaluation
#7
Vickie H Southall, Janet B Wright, Tia Campbell, Margaret K Bassett, Julie A Strunk, Suzanne E Trotter
Evaluation of one's school nurse practice is one standard in the school nurse's scope and standards of professional practice. The Virginia School Nurse Institute Partnership (SNIP) identified the need to develop a concise self-evaluation tool that school nurses and their nurse and non-nurse employers could use to appropriately document a school nurse's practice. The purpose of this article is to provide a self-evaluation tool that the school nurse and his or her employers can use to evaluate professional school nurse practice...
March 2017: NASN School Nurse
https://www.readbyqxmd.com/read/28225466/the-use-of-social-media-in-graduate-medical-education-a-systematic-review
#8
Madeline Sterling, Peggy Leung, Drew Wright, Tara F Bishop
PURPOSE: Despite the growing presence of social media in graduate medical education (GME), few studies have attempted to characterize their effect on residents and their training. The authors conducted a systematic review of the peer-reviewed literature to understand the effect of social media on resident (1) education, (2) recruitment, and (3) professionalism. METHOD: The authors identified English-language peer-reviewed articles published through November 2015 using Medline, Embase, Cochrane, PubMed, Scopus, and ERIC...
February 21, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28225443/bringing-big-data-to-the-forefront-of-healthcare-delivery-the-experience-of-carolinas-healthcare-system
#9
Michael F Dulin, Carol A Lovin, Jean A Wright
The use of big data to transform care delivery is rapidly becoming a reality. To deliver on the promise of value-based care, providers must know the key drivers of wellness at the patient and community levels, as well as understand resource constraints and opportunities to improve efficiency in the health-care system itself. Data are the linchpin. By gathering the right data and finding innovative ways to glean knowledge, we can improve clinical care, advance the health of our communities, improve the lives of our patients, and operate more efficiently...
January 2017: Frontiers of Health Services Management
https://www.readbyqxmd.com/read/28222836/presumptive-spontaneous-lysosomal-storage-like-disease-in-a-crl-cd1-icr-mouse
#10
Krista M Hernon, Tiffany L Whitcomb, Lori Davis, Timothy K Cooper
A clinically unremarkable 4.5-mo-old female Crl:CD1(ICR) VAF/Elite mouse was euthanized for scheduled sentinel processing. Gross necropsy findings included significant hepatosplenomegaly and visceral lymphadenomegaly, resulting in a preliminary gross diagnosis of lymphoma. Histology revealed florid accumulations of large, 'foamy' macrophages present in the bone marrow, small intestines, and viscera including liver, spleen, lymph nodes, thymus, uterus, and ovaries. The cytoplasm of these cells was abundant, stained pale blue with Wright-Giemsa and was periodic acid-Schiff positive...
February 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28222517/association-of-central-arterial-stiffness-and-pressure-pulsatility-with-mild-cognitive-impairment-and-dementia-the-atherosclerosis-risk-in-communities-study-neurocognitive-study-aric-ncs
#11
Michelle L Meyer, Priya Palta, Hirofumi Tanaka, Jennifer A Deal, Jacqueline Wright, David S Knopman, Michael Griswold, Thomas H Mosley, Gerardo Heiss
BACKGROUND: The association of central arterial stiffness and pressure pulsatility with mild cognitive impairment (MCI) and dementia is not well characterized in the population-based setting. OBJECTIVE: The aim of this study was to quantify the cross-sectional association of arterial stiffness and pressure pulsatility with MCI and dementia among 4,461 older white and black adults from the population-based Atherosclerosis Risk in Communities Study-Neurocognitive Study...
February 10, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28222254/pushing-the-boundaries-of-high-content-imaging
#12
EDITORIAL
Graham D Wright, Alex M Ward, Frederic Bard, Meredith E K Calvert
No abstract text is available yet for this article.
February 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/28221824/surviving-in-a-cosexual-world-a-cost-benefit-analysis-of-dioecy-in-tropical-trees
#13
Marjolein Bruijning, Marco D Visser, Helene C Muller-Landau, S Joseph Wright, Liza S Comita, Stephen P Hubbell, Hans de Kroon, Eelke Jongejans
Dioecy has a demographic disadvantage compared with hermaphroditism: only about half of reproductive adults produce seeds. Dioecious species must therefore have fitness advantages to compensate for this cost through increased survival, growth, and/or reproduction. We used a full life cycle approach to quantify the demographic costs and benefits associated with dioecy while controlling for demographic differences between dioecious and hermaphroditic species related to other functional traits. The advantage of this novel approach is that we can focus on the effect of breeding system across a diverse tree community...
March 2017: American Naturalist
https://www.readbyqxmd.com/read/28221755/multilevel-ultra-fast-flexible-nanoscale-non-volatile-hybrid-graphene-oxide-titanium-oxide-memories
#14
V Karthik Nagareddy, Matthew D Barnes, Federico Zipoli, Khue T Lai, Arseny M Alexeev, Monica Felicia Craciun, C David Wright
Graphene oxide (GO) resistive memories offer the promise of low-cost environmentally-sustainable fabrication, high mechanical flexibility and high optical transparency, making them ideally suited to future flexible and transparent electronics applications. However, the dimensional and temporal scalability of GO memories, i.e. how small they can be made and how fast they can be switched, is an area that has received scant attention. Moreover, a plethora of GO resistive switching characteristics and mechanisms has been reported in the literature, sometimes leading to a confusing and conflicting picture...
February 21, 2017: ACS Nano
https://www.readbyqxmd.com/read/28220738/the-influence-of-hiv-infection-on-the-age-dependence-of-squamous-cell-carcinoma-of-the-skin-in-south-africa
#15
B L Diffey, M Norval, P N Albers, C Y Wright
BACKGROUND: Cancer incidence typically increases with age, but it is not known whether ethnic characteristics influence the age dependence of squamous cell carcinoma of the skin (SCC). OBJECTIVES: (i) To determine the age dependence of SCC in the black African, coloured and white population groups of South Africa (SA); and (ii) to show whether any differences in the rate of change of age dependence could be influenced by diversity in behaviour and lifestyle, especially with regard to the prevalence of HIV infection, rather than by a fundamental variation in cancer biology between the populations...
January 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28220043/partitioning-heritability-analysis-reveals-a-shared-genetic-basis-of-brain-anatomy-and-schizophrenia
#16
P H Lee, J T Baker, A J Holmes, N Jahanshad, T Ge, J-Y Jung, Y Cruz, D S Manoach, D P Hibar, J Faskowitz, K L McMahon, G I de Zubicaray, N H Martin, M J Wright, D Öngür, R Buckner, J Roffman, P M Thompson, J W Smoller
No abstract text is available yet for this article.
February 21, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28220035/case-report-modified-laparoscopic-subtotal-cholecystectomy-an-alternative-approach-to-the-difficult-gallbladder
#17
Michael S Segal, Richard H Huynh, George O Wright
BACKGROUND Laparoscopic cholecystectomy is a commonly performed surgical procedure. In certain situations visualization of the Callot triangle can become difficult due to inflammation, adhesions, and sclerosing of the anatomy. Without being able to obtain the "critical view of safety" (CVS), there is increased risk of damage to vital structures. An alternative approach to the conventional conversion to an open cholecystectomy (OC) would be a laparoscopic subtotal cholecystectomy (LSC). CASE REPORT We present a case of a 56-year-old male patient with acute cholecystitis with a "difficult gallbladder" managed with LSC...
February 21, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28219708/novel-technique-to-determine-the-pka-of-clonidine-at-prejunctional-%C3%AE-2-adrenoceptors-in-cardiac-and-vascular-sympathetic-transmission
#18
James A Angus, Pravin Rajasekaran, Christine E Wright
Analytical pharmacology draws heavily on the concept of equilibrium of agonist and silent antagonist concentrations competing at a specific receptor site. This condition breaks down in nerve transmission when transmitter release is inhibited by prejunctional α2-adrenoceptors activated by an agonist such as clonidine. We have developed a method that allows the agonist dissociation constant KA of clonidine to be determined in a robust isolated right atrial assay of mouse, rat and guinea pig. By applying low numbers of field pulses 1-4 to prevent autoinhibitory feedback, clonidine shifted the nerve pulse stimulation-tachycardia curves to the right...
February 17, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28218233/multi-institutional-study-of-nuclear-kifc1-as-a-biomarker-of-poor-prognosis-in-african-american-women-with-triple-negative-breast-cancer
#19
Angela Ogden, Chakravarthy Garlapati, Xiaoxian Bill Li, Ravi Chakra Turaga, Gabriela Oprea-Ilies, Nikita Wright, Shristi Bhattarai, Karuna Mittal, Ceyda Sönmez Wetherilt, Uma Krishnamurti, Michelle D Reid, Mildred Jones, Meenakshi Gupta, Remus Osan, Sonal Pattni, Ansa Riaz, Sergey Klimov, Arundhati Rao, Guilherme Cantuaria, Padmashree C G Rida, Ritu Aneja
Nuclear KIFC1 (nKIFC1) predicts worse outcomes in breast cancer, but its prognostic value within racially distinct triple-negative breast cancer (TNBC) patients is unknown. Thus, nKIFC1 expression was assessed by immunohistochemistry in 163 African American (AA) and 144 White TNBC tissue microarrays (TMAs) pooled from four hospitals. nKIFC1 correlated significantly with Ki67 in White TNBCs but not in AA TNBCs, suggesting that nKIFC1 is not merely a surrogate for proliferation in AA TNBCs. High nKIFC1 weighted index (WI) was associated with significantly worse overall survival (OS), progression-free survival (PFS), and distant metastasis-free survival (DMFS) (Hazard Ratios [HRs] = 3...
February 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28217660/reverse-total-shoulder-arthroplasty-research-models
#20
Stefano Petrillo, Umile Giuseppe Longo, Lawrence V Gulotta, Alessandra Berton, Andreas Kontaxis, Timothy Wright, Vincenzo Denaro
PURPOSE: the past decade has seen a considerable increase in the use of research models to study reverse total shoulder arthroplasty (RTSA). Nevertheless, none of these models has been shown to completely reflect real in vivo conditions. METHODS: we performed a systematic review of the literature matching the following key words: "reverse total shoulder arthroplasty" or "reverse total shoulder replacement" or "reverse total shoulder prosthesis" and "research models" or "biomechanical models" or "physical simulators" or "virtual simulators"...
October 2016: Joints
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