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https://www.readbyqxmd.com/read/28214702/triploid-atlantic-salmon-shows-similar-performance-fatty-acid-composition-and-proteome-response-to-diploids-during-early-freshwater-rearing
#1
Waldo G Nuez-Ortín, Chris G Carter, Richard Wilson, Ira R Cooke, Gianluca Amoroso, Jennifer M Cobcroft, Peter D Nichols
There is currently renewed interest in farming triploid Atlantic salmon. Improving farming requires identifying triploid specific phenotypic and physiological traits that are uniquely derived from ploidy per se and developed under optimal growing conditions. This study investigated firstly, the impact of ploidy on growth performance and whole body composition of Atlantic salmon at different early freshwater stages [34dph (days post-hatching) alevin, 109dph fry, and 162dph parr] and secondly, whether phenotypic differences at these stages were reflected in protein samples collected from whole fish, white muscle or liver tissue...
February 11, 2017: Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics
https://www.readbyqxmd.com/read/28214041/why-intensity-is-not-a-bad-word-optimizing-health-status-at-any-age
#2
REVIEW
Gary R Hunter, Eric P Plaisance, Stephen J Carter, Gordon Fisher
Age-related declines in health and function make locomotion increasingly difficult leading to reductions in non-exercise activity thermogenesis (NEAT), skeletal muscle size and strength, and increased adiposity. Exercise is an important strategy to attenuate loss of function through the life cycle. Despite claims to the contrary, high-intensity exercise is important for the prevention of obesity and sarcopenia with advancing age. Therefore, the purpose of this mini-review is to present literature supporting the contention that low volume, high-intensity aerobic and/or resistance training can slow sarcopenia, sustain ease of movement, stimulate NEAT, and attenuate the accretion of fat mass...
February 9, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28213837/brief-report-meeting-the-needs-of-medically-hospitalized-adults-with-autism-a-provider-and-patient-toolkit
#3
Jocelyn Carter, Sarabeth Broder-Fingert, Ann Neumeyer, Ann Giauque, Ann Kao, Christiana Iyasere
In an effort to meet the needs of adults with autism spectrum disorder (ASD) while hospitalized, a team of experts and providers from Massachusetts General Hospital (MGH), MGH for Children as well as parents of individuals with ASD was sparked in 2013. This became a multidisciplinary collaborative, the MGH Autism Care Collaborative, to improve adult care for inpatients with ASD. The collaborative was created with three goals in mind: (1) to educate internal medicine adult inpatient providers and staff on the unique needs of adults with ASD when hospitalized; (2) to create ASD specific resources for internal medicine adult inpatient providers; (3) to optimize patient care from admission to discharge among adults with ASD admitted to internal medicine services...
February 17, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28213626/effectiveness-of-screening-for-craniosynostosis-with-ultrasound-a-retrospective-review
#4
Kent M Hall, David A Besachio, Matthew D Moore, Adrian J Mora, William R Carter
BACKGROUND: Minimizing the ionizing radiation dose to children is fundamental to pediatric radiology. The most widely accepted imaging examination for evaluating craniosynostosis is computed tomography (CT) of the head, an examination that involves ionizing radiation. OBJECTIVE: To determine if sonography of the cranial sutures is an adequate screening examination for the diagnosis of craniosynostosis in patients with abnormal skull shape. MATERIALS AND METHODS: A retrospective review of all cranial suture ultrasound (US) examinations performed during the course of a 3-year period (July 2012 - September 2015) was undertaken...
February 17, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28209591/psychosocial-therapies-for-the-adjunctive-treatment-of-bipolar-disorder-in-adults-network-meta-analysis
#5
REVIEW
Mary Lou Chatterton, Emily Stockings, Michael Berk, Jan J Barendregt, Rob Carter, Cathrine Mihalopoulos
BackgroundFew trials have compared psychosocial therapies for people with bipolar affective disorder, and conventional meta-analyses provided limited comparisons between therapies.AimsTo combine evidence for the efficacy of psychosocial interventions used as adjunctive treatment of bipolar disorder in adults, using network meta-analysis (NMA).MethodSystematic review identified studies and NMA was used to pool data on relapse to mania or depression, medication adherence, and symptom scales for mania, depression and Global Assessment of Functioning (GAF)...
February 16, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28209138/using-whole-genome-sequencing-to-investigate-transmission-in-a-multi-host-system-bovine-tuberculosis-in-new-zealand
#6
Joseph Crispell, Ruth N Zadoks, Simon R Harris, Brent Paterson, Desmond M Collins, Geoffrey W de-Lisle, Paul Livingstone, Mark A Neill, Roman Biek, Samantha J Lycett, Rowland R Kao, Marian Price-Carter
BACKGROUND: Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is an important livestock disease raising public health and economic concerns around the world. In New Zealand, a number of wildlife species are implicated in the spread and persistence of bTB in cattle populations, most notably the brushtail possum (Trichosurus vulpecula). Whole Genome Sequenced (WGS) M. bovis isolates sourced from infected cattle and wildlife across New Zealand were analysed. Bayesian phylogenetic analyses were conducted to estimate the substitution rate of the sampled population and investigate the role of wildlife...
February 16, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28208726/phenology-of-a-vegetation-barrier-and-resulting-impacts-on-near-highway-particle-number-and-black-carbon-concentrations-on-a-school-campus
#7
Christina H Fuller, David R Carter, Matthew J Hayat, Richard Baldauf, Rebecca Watts Hull
Traffic-related air pollution is a persistent concern especially in urban areas where populations live in close proximity to roadways. Innovative solutions are needed to minimize human exposure and the installation of vegetative barriers shows potential as a method to reduce near-road concentrations. This study investigates the impact of an existing stand of deciduous and evergreen trees on near-road total particle number (PNC) and black carbon (BC) concentrations across three seasons. Measurements were taken during spring, fall and winter on the campus of a middle school in the Atlanta (GA, USA) area at distances of 10 m and 50 m from a major interstate highway...
February 8, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28208496/extension-of-discrete-tribocharging-models-to-continuous-size-distributions
#8
Dylan Carter, Christine Hartzell
Triboelectric charging, the phenomenon by which electrical charge is exchanged during contact between two surfaces, has been known to cause significant charge separation in granular mixtures, even between chemically identical grains. This charging is a stochastic size-dependent process resulting from random collisions between grains. The prevailing models and experimental results suggest that, in most cases, larger grains in a mixture of dielectric grains acquire a positive charge, while smaller grains charge negatively...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28208252/high-confidence-qualitative-identification-of-organophosphorus-nerve-agent-adducts-to-human-butyrylcholinesterase
#9
Thomas P Mathews, Melissa D Carter, Darryl Johnson, Samantha L Isenberg, Leigh Ann Graham, Jerry D Thomas, Rudolph C Johnson
In this study, a data-dependent, high-resolution tandem mass spectrometry (ddHRMS/MS) method capable of detecting all organophosphorus nerve agent (OPNA) adducts to human butyrylcholinesterase (BChE) was developed. After an exposure event, immunoprecipitation from blood with a BChE-specific antibody and digestion with pepsin produces a nine amino acid peptide containing the OPNA adduct. Signature product ions of this peptic BChE nonapeptide (FGES*AGAAS) offer a route to broadly screen for OPNA exposure. Taking this approach on an HRMS instrument identifies biomarkers, including unknowns, with high mass accuracy...
February 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28207410/data-mining-for-age-related-tsh-reference-intervals-in-adulthood
#10
Christopher-John L Farrell, Lan Nguyen, Andrew C Carter
No abstract text is available yet for this article.
February 16, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28203676/selective-separation-of-americium-from-europium-using-2-9-bis-triazine-1-10-phenanthrolines-in-ionic-liquids-a-new-twist-on-an-old-story
#11
Neil J Williams, Jérémy Dehaudt, Vyacheslav S Bryantsev, Huimin Luo, Carter W Abney, Sheng Dai
Bis-triazine phenanthrolines have shown great promise for f-block metal separations, attributable to their highly preorganized structure, nitrogen donors, and more enhanced covalent bonding with actinides over lanthanides. However, their limited solubility in traditional solvents remains a technological bottleneck. Herein we report our recent work using a simple 2,9-bis(triazine)-1,10-phenanthroline (Me-BTPhen) dissolved in an ionic liquid (IL), demonstrating the efficacy of IL extraction systems for the selective separation of americium from europium, achieving separation factors in excess of 7500 and selectively removing up to 99% of the americium...
February 16, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28203622/a-case-of-eczema-coxsackium-with-erythema-multiforme-like-histopathology-in-a-14-year-old-boy-with-chronic-graft-versus-host-disease
#12
Patricia K Miller, Muhammad Zain-Ul-Abideen, Joan Paul, Ann E Perry, Konstantinos Linos, Joi B Carter, Joanne Kurtzberg, Julianne A Mann
No abstract text is available yet for this article.
January 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/28202494/fumarate-hydratase-is-a-critical-metabolic-regulator-of-hematopoietic-stem-cell-functions
#13
Amelie V Guitart, Theano I Panagopoulou, Arnaud Villacreces, Milica Vukovic, Catarina Sepulveda, Lewis Allen, Roderick N Carter, Louie N van de Lagemaat, Marcos Morgan, Peter Giles, Zuzanna Sas, Marta Vila Gonzalez, Hannah Lawson, Jasmin Paris, Joy Edwards-Hicks, Katrin Schaak, Chithra Subramani, Deniz Gezer, Alejandro Armesilla-Diaz, Jimi Wills, Aaron Easterbrook, David Coman, Chi Wai Eric So, Donal O'Carroll, Douglas Vernimmen, Neil P Rodrigues, Patrick J Pollard, Nicholas M Morton, Andrew Finch, Kamil R Kranc
Strict regulation of stem cell metabolism is essential for tissue functions and tumor suppression. In this study, we investigated the role of fumarate hydratase (Fh1), a key component of the mitochondrial tricarboxylic acid (TCA) cycle and cytosolic fumarate metabolism, in normal and leukemic hematopoiesis. Hematopoiesis-specific Fh1 deletion (resulting in endogenous fumarate accumulation and a genetic TCA cycle block reflected by decreased maximal mitochondrial respiration) caused lethal fetal liver hematopoietic defects and hematopoietic stem cell (HSC) failure...
February 15, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28201956/hiv-screening-and-the-affordable-care-act
#14
Greg Carter, Christopher Owens, Hsien-Chang Lin
Men continue to bear disproportionate accounts of HIV diagnoses. The Patient Protection and Affordable Care act aims to address health care disparities by recommending preventative services, including HIV screening, expanding community health centers, and increasing the healthcare workforce. This study examined the decision making of physician and primary care health providers to provide HIV screenings. A quasi-experimental design was used to estimate the effects of the Affordable Care Act on provider-initiated HIV screening...
March 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/28199679/higher-t-cell-responses-induced-by-dna-rad5-hiv-1-preventive-vaccine-are-associated-with-lower-hiv-1-infection-risk-in-an-efficacy-trial
#15
Holly E Janes, Kristen W Cohen, Nicole Frahm, Stephen C De Rosa, Brittany Sanchez, John Hural, Craig A Magaret, Shelly Karuna, Carter Bentley, Raphael Gottardo, Greg Finak, Douglas Grove, Mingchao Shen, Barney S Graham, Richard A Koup, Mark J Mulligan, Beryl Koblin, Susan P Buchbinder, Michael C Keefer, Elizabeth Adams, Chuka Anude, Lawrence Corey, Magdalena Sobieszczyk, Scott M Hammer, Peter B Gilbert, M Juliana McElrath
No abstract text is available yet for this article.
February 12, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28199324/establishing-a-reliable-framework-for-harnessing-the-creative-power-of-the-scientific-crowd
#16
Adrian J Carter, Amy Donner, Wen Hwa Lee, Chas Bountra
Discovering new medicines is difficult and increasingly expensive. The pharmaceutical industry has responded to this challenge by embracing open innovation to access external ideas. Historically, partnerships were usually bilateral, and the drug discovery process was shrouded in secrecy. This model is rapidly changing. With the advent of the Internet, drug discovery has become more decentralised, bottom-up, and scalable than ever before. The term open innovation is now accepted as just one of many terms that capture different but overlapping levels of openness in the drug discovery process...
February 2017: PLoS Biology
https://www.readbyqxmd.com/read/28198649/fatal-drownings-in-fiji
#17
Kathryn Murray, Peter Carter
Drowning is a newly comprehended public health concern in Fiji. Defined as "the process of experiencing respiratory impairment from submersions or immersion in liquid," drowning has been identified as one of Fiji's 5 leading causes of death for those aged 1 to 29 years. The aim of this article was to develop the most parsimonious model that can be used to explain the number of monthly fatal drowning cases in Fiji. Based on a cross-section of 187 drowning incidents from January 2012 to April 2015, this observational study found the number of monthly drownings in Fiji was significantly affected by monthly rainfall ( P = ...
January 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28197597/the-effect-of-sodium-species-on-methanol-synthesis-and-water-gas-shift-cu-zno-catalysts-utilising-high-purity-zincian-georgeite
#18
Simon A Kondrat, Paul J Smith, James H Carter, James S Hayward, Geoffrey J Pudge, Greg Shaw, Michael S Spencer, Jonathan K Bartley, Stuart H Taylor, Graham J Hutchings
The effect of sodium species on the physical and catalytic properties of Cu/ZnO catalysts derived from zincian georgeite has been investigated. Catalysts prepared with <100 ppm to 2.1 wt% Na(+), using a supercritical CO2 antisolvent technique, were characterised and tested for the low temperature water-gas shift reaction and also CO2 hydrogenation to methanol. It was found that zincian georgeite catalyst precursor stability was dependent on the Na(+) concentration, with the 2.1 wt% Na(+)-containing sample uncontrollably ageing to malachite and sodium zinc carbonate...
February 15, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28196890/dync1h1-mutations-associated-with-neurological-diseases-compromise-processivity-of-dynein-dynactin-cargo-adaptor-complexes
#19
Ha Thi Hoang, Max A Schlager, Andrew P Carter, Simon L Bullock
Mutations in the human DYNC1H1 gene are associated with neurological diseases. DYNC1H1 encodes the heavy chain of cytoplasmic dynein-1, a 1.4-MDa motor complex that traffics organelles, vesicles, and macromolecules toward microtubule minus ends. The effects of the DYNC1H1 mutations on dynein motility, and consequently their links to neuropathology, are not understood. Here, we address this issue using a recombinant expression system for human dynein coupled to single-molecule resolution in vitro motility assays...
February 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28195872/rethinking-our-definition-of-postoperative-success-a-comparative-analysis-of-three-upper-eyelid-retraction-repair-techniques-using-novel-metrics-to-capture-functional-and-aesthetic-outcomes
#20
Jacob A Evans, Thomas J E Clark, M Bridget Zimmerman, Richard C Allen, Jeffrey A Nerad, Keith D Carter, Erin M Shriver
PURPOSE: To compare 3 upper eyelid retraction repair techniques and introduce novel metrics, which enhance the analysis of postoperative aesthetic outcomes. METHODS: Retrospective review with Image J 1.48 digital analysis of patients who underwent repair of thyroid-related upper eyelid retraction at the University of Iowa from 1996 to 2014 via 1 of 3 surgical techniques, septum-opening levator recession with Muellerectomy, modified septum-preserving levator recession with Muellerectomy, and modified septum-preserving full-thickness blepharotomy, was conducted...
February 10, 2017: Ophthalmic Plastic and Reconstructive Surgery
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