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https://www.readbyqxmd.com/read/27916564/peroral-endoscopic-myotomy-after-gastric-bypass-an-effective-solution-for-de-novo-achalasia
#1
Ran B Luo, Domingo Montalvo, Santiago Horgan
No abstract text is available yet for this article.
October 8, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27913453/movement-patterns-of-cheetahs-acinonyx-jubatus-in-farmlands-in-botswana
#2
L K Van der Weyde, T Y Hubel, J Horgan, J Shotton, R McKenna, A M Wilson
Botswana has the second highest population of cheetah (Acinonyx jubatus) with most living outside protected areas. As a result, many cheetahs are found in farming areas, bringing them into conflict with people. This study aimed to look at movement patterns of cheetahs in farming environments to determine whether cheetahs have adapted their movements in these human-dominated landscapes. We fitted high-time resolution GPS collars to cheetahs in the Ghanzi farmlands of Botswana. GPS locations were used to calculate home range sizes as well as number and duration of visits to landscape features using a time-based local convex hull method...
December 2, 2016: Biology Open
https://www.readbyqxmd.com/read/27911073/reducing-risky-alcohol-use-what-health-care-systems-can-do
#3
Amity E Quinn, Mary Brolin, Maureen T Stewart, Brooke Evans, Constance Horgan
Risky, non-dependent alcohol use is prevalent in the United States, affecting 25% of adults (Centers for Disease Control and Prevention, 2014b). Massachusetts has higher rates of alcohol use and binge drinking than most states (Substance Abuse and Mental Health Services Administration, 2015). Serious physical, social, and economic consequences result. Excessive alcohol use contributes to cancer, cardiovascular disease, sleep disorders, birth defects, motor vehicle injuries, and suicide, and it complicates management of chronic illnesses (Green, McKnight-Eily, Tan, Mejia, & Denny, 2016; Laramee et al...
April 27, 2016: Issue Brief
https://www.readbyqxmd.com/read/27907234/shooting-alone-the-pre-attack-experiences-and-behaviors-of-u-s-solo-mass-murderers
#4
Paul Gill, James Silver, John Horgan, Emily Corner
This paper outlines the sociodemographic, developmental, antecedent attack, attack preparation, and commission properties of 115 mass murderers between 1990 and 2014. The results indicate that mass murderer attacks are usually the culmination of a complex mix of personal, political, and social drivers that crystalize at the same time to drive the individual down the path of violent action. We specifically focus upon areas related to prior criminal engagement, leakage, and attack location familiarity. Whether the violence comes to fruition is usually a combination of the availability and vulnerability of suitable targets that suit the heady mix of personal and political grievances and the individual's capability to engage in an attack from both a psychological and technical capability standpoint...
December 1, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27902483/androgen-receptor-phosphorylation-status-at-serine-578-predicts-poor-outcome-in-prostate-cancer-patients
#5
Patek Sc, Willder Jm, Heng Js, Taylor B, Horgan Pg, Leung Hy, Underwood Ma, Edwards J
PURPOSE: Prostate cancer growth is dependent upon androgen receptor (AR) activation, regulated via phosphorylation. Protein kinase C (PKC) is one kinase that can mediate AR phosphorylation. This study aimed to establish if AR phosphorylation by PKC is of prognostic significance. METHODS: Immunohistochemistry for AR, AR phosphorylated at Ser-81 (pARS81), AR phosphorylated at Ser-578 (pARS578), PKC and phosphorylated PKC (pPKC) was performed on 90 hormone-naïve prostate cancer specimens...
November 25, 2016: Oncotarget
https://www.readbyqxmd.com/read/27876806/a-randomised-controlled-trial-comparing-a-dietary-antiplatelet-the-water-soluble-tomato-extract-fruitflow-with-75%C3%A2-mg-aspirin-in-healthy-subjects
#6
N O'Kennedy, L Crosbie, H-J Song, X Zhang, G Horgan, A K Duttaroy
BACKGROUND/OBJECTIVES: Increasing numbers of food ingredients are gaining acknowledgement, via regulated health claims, of benefits to human health. One such is a water-soluble tomato extract, Fruitflow (FF), a dietary antiplatelet. We examined relative platelet responses to FF and to 75 mg aspirin (ASA) in healthy subjects. SUBJECTS/METHODS: A total of 47 healthy subjects completed a double-blinded randomised controlled trial following a crossover design. Acute and 7-day treatments with 75 mg ASA were compared with control with and without concomitant FF, over a 5-h timecourse...
November 23, 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27873459/bedside-rounds
#7
Fiona C Horgan
No abstract text is available yet for this article.
November 22, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27873100/the-pretreatment-systemic-inflammatory-response-is-an-important-determinant-of-poor-pathologic-response-for-patients-undergoing-neoadjuvant-therapy-for-rectal-cancer
#8
Stephan B Dreyer, Arfon G M T Powell, Stephen T McSorley, Ashita Waterston, James J Going, Joanne Edwards, Donald C McMillan, Paul G Horgan
BACKGROUND: Not all patients respond equally to neoadjuvant chemoradiotherapy (nCRT), with subsequent effects on survival. The systemic inflammatory response has been shown to predict long-term outcomes in colorectal cancer. The current study examined the association between systemic inflammation and nCRT in patients with rectal cancer. METHODS: Between 1999 and 2010, patients who underwent nCRT were identified. Serum measurements of hemoglobin, C-reactive protein, albumin, modified Glasgow prognostic score (mGPS), and differential white cell counts were obtained before and after nCRT...
November 21, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27826775/analysis-of-lesion-localisation-at-colonoscopy-outcomes-from-a-multi-centre-u-k-study
#9
Susan J Moug, Spyridon Fountas, Mark S Johnstone, Adam S Bryce, Andrew Renwick, Lindsey J Chisholm, Kathryn McCarthy, Amy Hung, Robert H Diament, John R McGregor, Myo Khine, James D Saldanha, Khurram Khan, Graham Mackay, E Fiona Leitch, Ruth F McKee, John H Anderson, Ben Griffiths, Alan Horgan, Sonia Lockwood, Carly Bisset, Richard Molloy, Mark Vella
BACKGROUND: Colonoscopy is currently the gold standard for detection of colorectal lesions, but may be limited in anatomically localising lesions. This audit aimed to determine the accuracy of colonoscopy lesion localisation, any subsequent changes in surgical management and any potentially influencing factors. METHODS: Patients undergoing colonoscopy prior to elective curative surgery for colorectal lesion/s were included from 8 registered U.K. sites (2012-2014)...
November 8, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27822634/a-postoperative-systemic-inflammation-score-predicts-short-and-long-term-outcomes-in-patients-undergoing-surgery-for-colorectal-cancer
#10
David G Watt, Stephen T McSorley, James H Park, Paul G Horgan, Donald C McMillan
BACKGROUND: Following surgery, a significant proportion of patients develop postoperative complications that are associated with poorer long-term survival. Stereotypical markers of the systemic inflammatory response (SIR) have been shown to identify patients at increased risk of developing such complications. The aim of the present study was to examine the prognostic value of a postoperative systemic inflammation-based score in patients undergoing potentially curative surgery for colorectal cancer...
November 7, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27812236/effects-of-nitrogen-on-egg-laying-inhibition-and-ovicidal-response-in-planthopper-resistant-rice-varieties
#11
Finbarr G Horgan, Thanga Suja Srinivasan, Bhaskar S Naik, Angelee Fame Ramal, Carmencita C Bernal, Maria Liberty P Almazan
A series of experiments was set up to examine the effects of nitrogen on rice (Oryza sativa L.) resistance against Nilaparvata lugens (Stål) and Sogatella furcifera (Horváth). Egg laying by N. lugens was reduced on the indica variety IR60. Nymph biomass (N. lugens and S. furcifera) was also lower on IR60: this was associated with low honeydew production and a high proportion of xylem-derived honeydew in N. lugens but not in S. furcifera. Nitrogen increased egg-laying by S. furcifera and increased N...
November 2016: Crop Protection
https://www.readbyqxmd.com/read/27787481/complications-of-robotic-foregut-surgery-risks-and-advantages
#12
Ran B Luo, Domingo Montalvo, Toshiaki Suzuki, Bryan J Sandler, Garth R Jacobsen, Santiago Horgan
INTRODUCTION: Laparoscopic foregut surgeries are highly complex procedures that carry a high potential for morbidity and mortality should complications should occur. The robotic-assisted platform offers improved visualization of anatomy, optimal fine motor control, and a higher degree of instrumentation range of motion, which may potentially lead to better outcomes. This paper reviews the risks and benefits of the robotic platform in foregut procedures. EVIDENCE ACQUISITION: A web-based literature search was performed, in August 2016 using Pubmed, EMBASE, and Google Scholar from cited English publications from 1996 to 2016...
October 27, 2016: Minerva Chirurgica
https://www.readbyqxmd.com/read/27780193/short-term-breast-cancer-survival-in-relation-to-ethnicity-stage-grade-and-receptor-status-national-cohort-study-in-england
#13
Henrik Møller, Katherine Henson, Margreet Lüchtenborg, John Broggio, Jackie Charman, Victoria H Coupland, Elizabeth Davies, Ruth H Jack, Richard Sullivan, Peter Vedsted, Kieran Horgan, Neil Pearce, Arnie Purushotham
BACKGROUND: In the re-organisation of cancer registration in England in 2012, a high priority was given to the recording of cancer stage and other prognostic clinical data items. METHODS: We extracted 86 852 breast cancer records for women resident in England and diagnosed during 2012-2013. Information on age, ethnicity, socio-economic status, comorbidity, tumour stage, grade, morphology and oestrogen, progesterone and HER2 receptor status was included. The two-year cumulative risk of death from any cause was estimated with the Kaplan-Meier method, and univariate and multivariate Cox proportional hazards regressions were used to estimate hazard ratios (HR) and their 95% confidence intervals (95% CI)...
November 22, 2016: British Journal of Cancer
https://www.readbyqxmd.com/read/27759622/comment-on-the-important-role-for-intravenous-iron-in-perioperative-patient-blood-management-in-major-abdominal-surgery-a-randomized-controlled-trial
#14
Stephen T McSorley, David Mansouri, Paul G Horgan, Donald C McMillan
No abstract text is available yet for this article.
October 17, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27711949/advanced-endoscopic-imaging-european-society-of-gastrointestinal-endoscopy-esge-technology-review
#15
James E East, Jasper L Vleugels, Philip Roelandt, Pradeep Bhandari, Raf Bisschops, Evelien Dekker, Cesare Hassan, Gareth Horgan, Ralf Kiesslich, Gaius Longcroft-Wheaton, Ana Wilson, Jean-Marc Dumonceau
Background and aim: This technical review is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the utilization of advanced endoscopic imaging in gastrointestinal (GI) endoscopy. Methods: This technical review is based on a systematic literature search to evaluate the evidence supporting the use of advanced endoscopic imaging throughout the GI tract. Technologies considered include narrowed-spectrum endoscopy (narrow band imaging [NBI]; flexible spectral imaging color enhancement [FICE]; i-Scan digital contrast [I-SCAN]), autofluorescence imaging (AFI), and confocal laser endomicroscopy (CLE)...
October 6, 2016: Endoscopy
https://www.readbyqxmd.com/read/27698281/why-do-transient-ischemic-attack-patients-have-higher-early-stroke-recurrence-risk-than-those-with-ischemic-stroke-influence-of-patient-behavior-and-other-risk-factors-in-the-north-dublin-population-stroke-study
#16
Layan Akijian, Danielle Ní Chróinín, Elizabeth Callaly, Niamh Hannon, Michael Marnane, Áine Merwick, Órla Sheehan, Derek Hayden, Gillian Horgan, Joseph Duggan, Lorraine Kyne, Killian O'Rourke, Sean Murphy, Eamon Dolan, David Williams, Peter J Kelly
BACKGROUND: Few studies have directly compared stroke recurrence rates after stroke and transient ischemic attack, and the risk factors underlying early recurrence are poorly understood. We aimed to investigate risk factors for recurrent stroke after first stroke and transient ischemic attack in a population-based study. METHODS: The North Dublin Population Stroke Study applied multiple overlapping hot and cold pursuit methods, to ascertain hospital- and community-treated stroke and transient ischemic attack patients over a 12-month period...
October 3, 2016: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/27693865/help-seeking-behaviors-and-mental-well-being-of-first-year-undergraduate-university-students
#17
John Goodwin, Laura Behan, Peter Kelly, Karen McCarthy, Aine Horgan
University students demonstrate poor help-seeking behatabviors for their mental health, despite often reporting low levels of mental well-being. The aims of this study were to examine the help-seeking intentions and experiences of first year university students in terms of their mental well-betabing, and to extaplore these students' views on formal (e.g. psychiatrists) and informal (e.g. friends) help-seeking. Students from a universitytab in the Republic of Ireland (n=220) completed an online questionnaire which focused on mental well-being and help-seeking behaviors...
September 17, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27682892/implementation-of-client-incentives-within-a-recovery-navigation-program
#18
Mary Brolin, Maria Torres, Dominic Hodgkin, Constance Horgan, Margaret Lee, Elizabeth Merrick, Grant Ritter, Lee Panas, Natasha DeMarco, Jonna Hopwood, Andrea Gewirtz, John Straus, Janice Harrington, Nancy Lane
OBJECTIVE: Multiple detoxification admissions among clients with substance use disorders (SUD) are costly to the health care system. This study explored the impact on behavior and cost outcomes of recovery support navigator (RSN) services delivered with and without a contingent incentive intervention. METHODS: New intakes at four detoxification programs were offered RSN-only (N=1116) or RSN plus incentive (RSN+I; N=1551) services. The study used a group-level cross-over design with the intervention in place at each clinic reversed halfway through the enrollment period...
September 12, 2016: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/27678454/signal-transduction-and-activator-of-transcription-3-stat3-in-patients-with-colorectal-cancer-associations-with-the-phenotypic-features-of-the-tumour-and-host
#19
James H Park, Hester C Van Wyk, Donald C McMillan, Jean A Quinn, Dr Jennifer Clark, Campbell Sd Roxburgh, Paul G Horgan, Joanne Edwards
PURPOSE: In patients with colorectal cancer (CRC), a high-density local inflammatory infiltrate response is associated with improved survival, whereas elevated systemic inflammatory responses are associated with poor survival. One potential unifying mechanism is the IL-6/JAK/STAT3 pathway. The present study examines the relationship between tumour total STAT3 and phosphorylated STAT3Tyr705 (pSTAT3) expression, host inflammatory responses and survival in patients undergoing resection of stage I-III CRC...
September 27, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/27666157/step-count-accuracy-of-three-motion-sensors-for-older-and-frail-medical-inpatients
#20
Ruth McCullagh, Christina Dillon, Ann Marie O'Connell, N Frances Horgan, Suzanne Timmons
OBJECTIVES: To measure the step-count accuracy of an ankle-worn accelerometer, a thigh-worn accelerometer and one pedometer in older and frail inpatients. DESIGN: Cross-sectional design study. SETTING: Research room within a hospital. PARTICIPANTS: Convenience sample of inpatients aged ≥65 years, able to walk 20 metres unassisted, with or without a walking-aid. INTERVENTION: Patients completed a 40-minute programme of predetermined tasks while wearing the three motion sensors simultaneously...
September 22, 2016: Archives of Physical Medicine and Rehabilitation
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