keyword
MENU ▼
Read by QxMD icon Read
search

Elderly, productive

keyword
https://www.readbyqxmd.com/read/28315291/perspectives-of-stem-cell-based-therapy-for-age-related-retinal-degenerative-diseases
#1
Vladimir Holan, Barbora Hermankova, Jan Kossl
Retinal degenerative diseases, which include age-related macular degeneration, retinitis pigmentosa, diabetic retinopathy and glaucoma, mostly affect the elderly population, and are the most common cause of decreased quality of vision or even blindness. So far, there is no satisfactory treatment protocol to prevent, stop or cure these disorders. A great hope and promise for patients suffering from retinal diseases is represented by stem cell-based therapy which could replace diseased or missing retinal cells, and support regeneration...
March 17, 2017: Cell Transplantation
https://www.readbyqxmd.com/read/28302594/a-human-centered-design-methodology-to-enhance-the-usability-human-factors-and-user-experience-of-connected-health-systems-a-three-phase-methodology
#2
Richard Harte, Liam Glynn, Alejandro Rodríguez-Molinero, Paul Ma Baker, Thomas Scharf, Leo R Quinlan, Gearóid ÓLaighin
BACKGROUND: Design processes such as human-centered design, which involve the end user throughout the product development and testing process, can be crucial in ensuring that the product meets the needs and capabilities of the user, particularly in terms of safety and user experience. The structured and iterative nature of human-centered design can often present a challenge when design teams are faced with the necessary, rapid, product development life cycles associated with the competitive connected health industry...
March 16, 2017: JMIR Human Factors
https://www.readbyqxmd.com/read/28300045/-nature-cures-an-alternative-herbal-formulation-as-a-denture-cleanser
#3
R Sushma, Tanuja Tanaji Sathe, Anand Farias, Pronob Kumar Sanyal, Shashi Kiran
BACKGROUND: Candida albicans is one of the microorganisms which harbor the oral cavity, especially in elderly. However, the incidence of existence of this increases in patients using removable dental prosthesis. There is therefore a need to test the anticandidal efficacy of these cost-effective, easily available products to be used as routine denture cleansers. AIM AND OBJECTIVES: (1) To evaluate antifungal properties of triphala churna on the heat cure denture base material...
January 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28299221/endocrine-mucin-producing-sweat-gland-carcinoma-a-histological-challenge
#4
Mary Anne Brett, Samih Salama, Gabriella Gohla, Salem Alowami
Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a rare adnexal tumor of the skin with low-grade cytological features and neuroendocrine differentiation. It has a predilection for the skin of the eyelid, but has also been reported in the face and rarely extra-facial locations. The tumor is seen more frequently in women and on average affects the elderly. It is histologically and immunohistochemically analogous to solid papillary carcinoma of the breast/endocrine ductal carcinoma in situ with a nodular, solid, papillary, and/or cribriforming architecture, neuroendocrine differentiation, and mucin production...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28293192/indole-alkaloids-from-plants-as-potential-leads-for-antidepressant-drugs-a-mini-review
#5
Hazrulrizawati A Hamid, Aizi N M Ramli, Mashitah M Yusoff
Depression is the most common illness observed in the elderly, adults, and children. Antidepressants prescribed are usually synthetic drugs and these can sometimes cause a wide range of unpleasant side effects. Current research is focussed on natural products from plants as they are a rich source of potent new drug leads. Besides Hypericum perforatum (St. John's wort), the plants studied include Passiflora incarnata L. (passion flower), Mitragyna speciosa (kratom), Piper methysticum G. Forst (kava) and Valeriana officinalis L...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28288325/trochanteric-hip-fracture-during-cardioversion-therapy-a-case-report
#6
J Gómez, J Albareda, L Ezquerra
INTRODUCTION: Trochanteric hip fractures in elderly patients with osteoporosis are commonly caused by low energy trauma. The cardioversion therapy is an extremely rare cause of this type of fracture. PRESENTATION OF CASE: We report the case of a woman with hip fracture after cardioversion. DISCUSSION: We discuss the production mechanism of this injury and the importance of the care of the osteoporotic bone under these therapies. CONCLUSION: The propofol sedation should be complemented with skeletal muscle relaxants in the cardioversion therapy to avoid hip fracture in select patients with osteoporosis...
February 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28282401/nudging-to-prevent-the-purchase-of-incompatible-digital-products-online-an-experimental-study
#7
Gabriele Esposito, Penélope Hernández, René van Bavel, José Vila
Ensuring safe and satisfactory online shopping activity, especially among vulnerable consumers such as elderly and less educated citizens, is part of a larger set of consumer policy objectives seeking to strengthen trust in the electronic marketplace. This article contributes to that goal by testing the effectiveness of nudges intended to prevent the purchase of 'incompatible' digital products (i.e., those which cannot be used with the devices owned by consumers or the systems they operate). We ran a computerised lab experiment (n = 626) examining three types of nudges, the effects of age and education, and interaction effects between these variables and the nudges...
2017: PloS One
https://www.readbyqxmd.com/read/28269770/psychosocial-risk-and-protective-factors-and-incident-mild-cognitive-impairment-and-dementia-in-community-dwelling-elderly-findings-from-the-singapore-longitudinal-ageing-study
#8
Iris Rawtaer, Qi Gao, Ma Shwe Zin Nyunt, Lei Feng, Mei Sian Chong, Wee Shiong Lim, Tih-Shih Lee, Philip Yap, Keng Bee Yap, Tze Pin Ng
BACKGROUND: Indicators of social isolation or support such as living alone, loneliness, being married, and life satisfaction are possible psychosocial risk and protective factors for dementia. OBJECTIVE: We investigate the associations of these overlapping psychosocial factors with incident MCI-dementia (neurocognitive disorder) in a population cohort. METHODS: Using data from 1601 participants of the Singapore Longitudinal Ageing Study (SLAS) who were free of MCI or dementia at baseline and followed up to 8 years, we estimated hazards ratio (HR) of association of living alone, loneliness, being married, and high life satisfaction with incident MCI-dementia...
February 28, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28269347/uhf-wearable-battery-free-sensor-module-for-activity-and-falling-detection
#9
Nam Trung Dang, Thang Viet Tran, Wan-Young Chung
Falling is one of the most serious medical and social problems in aging population. Therefore taking care of the elderly by detecting activity and falling for preventing and mitigating the injuries caused by falls needs to be concerned. This study proposes a wearable, wireless, battery free ultra-high frequency (UHF) smart sensor tag module for falling and activity detection. The proposed tag is powered by UHF RF wave from reader and read by a standard UHF Electronic Product Code (EPC) Class-1 Generation-2 reader...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268967/two-threshold-energy-based-fall-detection-using-a-triaxial-accelerometer
#10
Angela Sucerquia, Jose D Lopez, Francisco Vargas
Elderly fall detection based on accelerometers is an active research area. Nowadays authors are addressing specific problems such as failure rates and energy consumption, but in most cases their strategies do not conciliate these objectives. In this paper we propose a double threshold based methodology with two novel detection features, a product between the sum vector magnitude and the signal magnitude area, and a normalization of the signal magnitude area over five 1 s windows. The methodology was validated using the public Mobifall dataset, and one developed for this work...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28262332/report-from-the-world-health-organization-s-third-product-development-for-vaccines-advisory-committee-pdvac-meeting-geneva-8-10th-june-2016
#11
Birgitte K Giersing, Johan Vekemans, Samantha Nava, David C Kaslow, Vasee Moorthy
The third meeting of WHO's Product Development for Vaccines Advisory Committee (PDVAC) was held in June 2016, with a remit to revisit the pathogen areas for which significant progress has occurred since recommendations from the 2015 meeting, as well as to consider new advances in the development of vaccines against other pathogens. Since the previous meeting, significant progress has been made with regulatory approvals of the first malaria and dengue vaccines, and the first phase III trials of a respiratory syncytial virus (RSV) vaccine candidate has started in the elderly and pregnant women...
March 2, 2017: Vaccine
https://www.readbyqxmd.com/read/28260511/clinically-relevant-drug-interactions-with-anti-alzheimer-s-drugs
#12
Filippo Caraci, Janet Sultana, Filippo Drago, Edoardo Spina
The aging world population had led to an increase in the prevalence of Alzheimer's disease (AD). The drugs used to slow down the onset of AD, galantamine, donepezil, rivastigmine and memantine, are generally well-tolerated. However, drug interactions between these drugs and other drugs are an important aspect of patient safety that should be borne in mind, particularly given the high burden of polypharmacy in the elderly. The aim of this review is to provide an updated review of clinically significant drug-drug interactions concerning drugs approved for AD...
March 3, 2017: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/28253985/mitochondria-targeted-molecules-as-potential-drugs-to-treat-patients-with-alzheimer-s-disease
#13
A P Reddy, P H Reddy
Alzheimer's disease (AD) is the most common multifactorial mental illness affecting the elderly population in the world. Its prevalence increases as person ages. There is no known drug or agent that can delay or prevent the AD and its progression. Extensive research has revealed that multiple cellular pathways involved, including amyloid beta production, mitochondrial structural and functional changes, hyperphosphorylation of Tau and NFT formation, inflammatory responses, and neuronal loss in AD pathogenesis...
2017: Progress in Molecular Biology and Translational Science
https://www.readbyqxmd.com/read/28250797/changes-in-peripheral-immune-cell-numbers-and-functions-in-octogenarian-walkers-an-acute-exercise-study
#14
Kornelis S M van der Geest, Qi Wang, Thijs M H Eijsvogels, Hans J P Koenen, Irma Joosten, Elisabeth Brouwer, Maria T E Hopman, Joannes F M Jacobs, Annemieke M H Boots
BACKGROUND: Age-related changes of the immune system, termed immunosenescence, may underlie the increased risk of infections and morbidity in the elderly. Little is known about the effects of acute exercise on peripheral immune parameters in octogenarians. Therefore, we investigated acute exercise-induced changes in phenotype and function of the immune system in octogenarians participating in the 2013 edition of the Nijmegen Four Days Marches. Blood sampling was performed at baseline and immediately after 4 days of the walking exercise (30 km/day)...
2017: Immunity & Ageing: I & A
https://www.readbyqxmd.com/read/28247317/adverse-health-events-related-to-self-medication-practices-among-elderly-a-systematic-review
#15
REVIEW
Médéa Locquet, Germain Honvo, Véronique Rabenda, Thierry Van Hees, Jean Petermans, Jean-Yves Reginster, Olivier Bruyère
BACKGROUND: Older adults often resort to self-medication to relieve symptoms of their current illnesses; however, the risks of this practice are multiplied in old age. In particular, this age group is more vulnerable to adverse drug events because of the physiological changes that occur due to senescence. OBJECTIVE: The aim of the study was to obtain an overview of the adverse health events related to self-medication among subjects aged 60 years and over through a systematic review of the literature...
February 28, 2017: Drugs & Aging
https://www.readbyqxmd.com/read/28247210/age-related-effects-on-maximal-and-rapid-hamstrings-quadriceps-strength-capacities-and-vertical-jump-power-in-young-and-older-females
#16
Ty B Palmer, Brittany N Followay, Brennan J Thompson
BACKGROUND AND AIMS: Declines in hamstrings and quadriceps maximal and rapid strength are commonly reported as a consequence of aging; however, few studies have investigated the influence of age on maximal and rapid hamstrings to quadriceps (H/Q) strength ratios. This study aimed to examine the effects of age on leg extension and flexion maximal and rapid torque production, H/Q strength ratios, and muscle power in healthy, young and old females. METHODS: Fifteen young (21 ± 2 years) and 15 old (69 ± 7 years) females performed 3 isometric leg extension and flexion maximal voluntary contractions (MVCs), from which peak torque (PT), early (0-30 ms) and late (0-200 ms) phase rate of torque development (RTD), and PT and RTD H/Q strength ratios were extracted...
February 28, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28245449/inflammation-and-thymus-ageing
#17
A Lepletier, A Alsharif, Ann P Chidgey
The thymus is primarily responsible for T cell production. However, it begins to recede in size and function, from early in life. This decreased generation of naive T cells during normal thymus ageing, or linked with pathology (i.e. chronic inflammation), leads to reduced T cell specificities, peripheral T cell imbalances, and higher susceptibilities to infections. Various clinical strategies for thymus and T cell recovery have been investigated, although no effective clinical treatments for the reconstitution of peripheral T cell diversity in severe immune deficiencies are available...
2017: Frontiers of Hormone Research
https://www.readbyqxmd.com/read/28244775/a-new-fructose-free-resistant-starch-type-iv-enriched-enteral-formula-improves-glycaemic-control-and-cardiovascular-risk-biomarkers-when-administered-for-six-weeks-to-elderly-diabetic-patients
#18
María Dolores Mesa García, Cruz Erika García-Rodríguez, María de la Cruz Rico, Concepción María Aguilera, Milagros Pérez-Rodríguez, Antonio Jesús Pérez-de-la-Cruz, Ángel Gil
BACKGROUND: Reducing the dietary glycaemic response has been proposed as a way to reduce the risk of diabetes complications. OBJECTIVE: The aim of the present study was to evaluate the glycaemic control and cardiovascular risk biomarkers in fragile, elderly type 2 diabetes patients after the intake of a new fructose-free diabetes-specific formula enriched with resistant-starch type IV and high in monounsaturated fatty acids. METHODS: Forty-one type 2 diabetes patients aged 78...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28242474/antiseizure-antidepressant-and-antipsychotic-medication-prescribing-in-elderly-nursing-home-residents
#19
Sai Praneeth R Bathena, Ilo E Leppik, Andres M Kanner, Angela K Birnbaum
OBJECTIVE: The incidence of epilepsy is highest in the elderly and the prevalence of epilepsy is higher in nursing home residents than in other cohorts. Co-medications that act in the central nervous system (CNS) are frequently prescribed in this population. The objective was to identify the most commonly prescribed antiseizure drugs (ASDs) and determine the frequency of use of antipsychotic and antidepressant medications in elderly nursing home residents receiving ASDs. METHODS: Data were obtained from a pharmacy database serving 18,752 patients in Minnesota and Wisconsin nursing homes...
February 24, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28236268/production-of-electrospun-fast-dissolving-drug-delivery-systems-with-therapeutic-eutectic-systems-encapsulated-in-gelatin
#20
Francisca Mano, Marta Martins, Isabel Sá-Nogueira, Susana Barreiros, João Paulo Borges, Rui L Reis, Ana Rita C Duarte, Alexandre Paiva
Fast-dissolving delivery systems (FDDS) have received increasing attention in the last years. Oral drug delivery is still the preferred route for the administration of pharmaceutical ingredients. Nevertheless, some patients, e.g. children or elderly people, have difficulties in swallowing solid tablets. In this work, gelatin membranes were produced by electrospinning, containing an encapsulated therapeutic deep-eutectic solvent (THEDES) composed by choline chloride/mandelic acid, in a 1:2 molar ratio. A gelatin solution (30% w/v) with 2% (v/v) of THEDES was used to produce electrospun fibers and the experimental parameters were optimized...
February 24, 2017: AAPS PharmSciTech
keyword
keyword
60300
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"