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https://www.readbyqxmd.com/read/28728972/numerical-characterisation-of-one-step-and-three-step-solar-air-heating-collectors-used-for-cocoa-bean-solar-drying
#1
Elder Mendoza Orbegoso, Rafael Saavedra, Daniel Marcelo, Raúl La Madrid
In the northern coastal and jungle areas of Peru, cocoa beans are dried using artisan methods, such as direct exposure to sunlight. This traditional process is time intensive, leading to a reduction in productivity and, therefore, delays in delivery times. The present study was intended to numerically characterise the thermal behaviour of three configurations of solar air heating collectors in order to determine which demonstrated the best thermal performance under several controlled operating conditions. For this purpose, a computational fluid dynamics model was developed to describe the simultaneous convective and radiative heat transfer phenomena under several operation conditions...
July 17, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28726047/dietary-acrylamide-exposure-was-associated-with-increased-cancer-mortality-in-chinese-elderly-men-and-women-a-11-year-prospective-study-of-mr-and-ms-os-hong-kong
#2
Zhao-Min Liu, Lap Ah Tse, Suzanne C Ho, Suyang Wu, Bailing Chen, Dicken Chan, Samuel Yeung-Shan Wong
AIM: Our study aims to investigate the association between dietary acrylamide exposure and cancer mortality among Chinese elderly. METHODS: A prospective cohort of 4000 elderly men and women aged 65 years and above (Mr. and Ms. OS Hong Kong study) was recruited from local communities from 2001 to 2003. Dietary exposure to acrylamide was evaluated at baseline based on a validated food frequency questionnaire and an acrylamide database from the 1st Hong Kong Total Diet Study...
July 19, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28721216/switch-to-restoration-therapy-in-a-testosterone-treated-central-hypogonadism-with-erythrocytosis
#3
B Cangiano, C Cacciatore, L Persani, M Bonomi
We describe a case of severe erythrocytosis caused by testosterone replacement therapy in a 66-year-old man affected with hypogonadotropic hypogonadism (HH) determining osteoporosis, resolved by switching to restoration therapy with clomiphene citrate. The patient complained fatigue, loss of libido and defective erections and a spontaneous vertebral fracture despite bisphosphonate therapy and vitamin D supplementation. The examinations proved isolated HH and he was therefore treated with testosterone gel with regression of specific manifestations but elevated hemoglobin and hematocrit values...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28721055/chitosan-oligosaccharide-improves-the-therapeutic-efficacy-of-sitagliptin-for-the-therapy-of-chinese-elderly-patients-with-type-2-diabetes-mellitus
#4
Lijie Zhao, Tingli Sun, Lina Wang
Sitagliptin improves glycemic control in type 2 diabetes mellitus (T2DM) patients but its side effects are undesirable. Chitosan oligosaccharide (COS) is expected to improve the therapeutic result as a natural product. A total of 200 elderly T2DM patients were evenly assigned into four groups: sitagliptin group (SG), receiving sitagliptin 100 mg/day; COS group (CG), receiving COS 100 mg/day; combination therapy of sitagliptin and COS group (SCG), receiving both sitagliptin and COS 100 mg/day; and placebo group (PG), receiving placebo 100 mg/day...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28716970/prolonged-force-depression-after-mechanically-demanding-contractions-is-largely-independent-of-ca-2-and-reactive-oxygen-species
#5
Sigitas Kamandulis, Felipe de Souza Leite, Andres Hernández, Abram Katz, Marius Brazaitis, Joseph D Bruton, Tomas Venckunas, Nerijus Masiulis, Dalia Mickeviciene, Nerijus Eimantas, Andrejus Subocius, Dilson E Rassier, Albertas Skurvydas, Niklas Ivarsson, Håkan Westerblad
Increased production of reactive oxygen/nitrogen species (ROS) and impaired cellular Ca(2+) handling are implicated in the prolonged low-frequency force depression (PLFFD) observed in skeletal muscle after both metabolically and mechanically demanding exercise. Metabolically demanding high-intensity exercise can induce PLFFD accompanied by ROS-dependent fragmentation of the sarcoplasmic reticulum Ca(2+) release channels, the ryanodine receptor (RyR)-1. We tested whether similar changes occur after mechanically demanding eccentric contractions...
July 17, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28714847/modulation-of-the-transcription-factor-nf-%C3%AE%C2%BAb-in-antigen-presenting-cells-by-bovine-respiratory-syncytial-virus-small-hydrophobic-protein
#6
Nicola Pollock, Geraldine Taylor, Fatoumatta Jobe, Efrain Guzman
Bovine respiratory syncytial virus (BRSV) is an important cause of respiratory disease in young cattle and is closely related to human RSV (HRSV), which causes severe respiratory disease in infants and the elderly. The RSV genome encodes a small hydrophobic (SH) protein with viroporin activity. Previous studies have shown that recombinant BRSV lacking the SH gene (rBRSVΔSH) is attenuated in the lungs, but not in the upper respiratory tract, of calves and mucosal vaccination with rBRSVΔSH induced long-lasting protective immunity...
July 17, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28713500/the-social-network-among-the-elderly-and-its-relationship-with-quality-of-life
#7
Fatemeh Bahramnezhad, Raheleh Chalik, Farideh Bastani, Masoumeh Taherpour, Elham Navab
INTRODUCTION: Attention to the needs of the elderly is a social necessity, and it seems that evaluating the social network and quality of life of the elderly can be useful in a better understanding of their needs. This study was performed to determine the relationship between the social network and the quality of life of the elderly in the city of Bojnoord in Iran. METHODS: In this cross-sectional study, 201 elderly people aged 60 years or more were selected by continuous and consecutive sampling method in Bojnoord, Iran in 2014...
May 2017: Electronic Physician
https://www.readbyqxmd.com/read/28701443/critical-elevation-of-international-normalized-ratio-in-an-elderly-woman-using-a-natural-health-product
#8
Kevin Pottie, Kamila Premji, Sitelle Léonie Cheskey
No abstract text is available yet for this article.
July 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28699240/the-prevalence-of-peripheral-intravenous-cannulae-and-pattern-of-use-a-point-prevalence-in-a-private-hospital-setting
#9
Kelvin Wong, Alannah Cooper, Janie Brown, Leanne Boyd, Michele Levinson
AIMS AND OBJECTIVES: to determine the prevalence and pattern of use of peripheral intravenous cannula (PIVC) in hospital wards. BACKGROUND: PIVC are commonly used in acute health care to directly access the bloodstream for the administration of medications, intravenous fluids (IVF) and blood products. PIVC are associated with multiple adverse events including hospital acquired bloodstream infection, thrombophlebitis, and pain/discomfort. Administration of IVF is associated with impaired mobility and nocturia which may increase falls risk in the elderly...
July 12, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28698988/medication-errors-a-characterisation-of-spontaneously-reported-cases-in-eudravigilance
#10
Victoria Newbould, Steven Le Meur, Thomas Goedecke, Xavier Kurz
INTRODUCTION: Medication errors recently became the focus of regulatory guidance in pharmacovigilance to support reporting, evaluation and prevention of medication errors. OBJECTIVE: This study aims to characterise spontaneously reported cases of medication errors in EudraVigilance over the period 2002-2015 before the release of EU good practice guidance. METHODS: Case reports were identified through the adverse reaction section where a Medical Dictionary for Regulatory Activities (MedDRA(®)) term is reported and included in the Standardised MedDRA(®) Query (SMQ) for medication errors...
July 11, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28697517/-cochlear-implants-in-children-and-adults
#11
Thomas Zahnert, Dirk Mürbe
About 4000 patients receive a cochlear implant in Germany every year. Adults have become the main group for cochlear implantation candidacy.Elderly people with progressive and profound hearing loss experienced high communication restraints due to the limits of conventional hearing aids in the past. Nowadays cochlear implants can be offered as a well-established extension to the supply chain of hearing systems. The option of cochlear implantation for children with profound hearing impairment has led to a paradigm shift in hearing rehabilitation...
June 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28681084/photobiomodulation-therapy-action-in-wound-repair-skin-induced-in-aged-rats-old-time-course-of-biomarkers-inflammatory-and-repair
#12
Franciane Barbieri Fiorio, Solange Almeida Dos Santos, Caroline Sobral de Melo Rambo, Camila Guerra Dalbosco, Andrey Jorge Serra, Brunno Lemes de Melo, Ernesto Cesar Pinto Leal-Junior, Paulo de Tarso Camillo de Carvalho
Previous studies have discussed an inverse correlation between age and wound healing, because it relates to the association of aging with a gradual decrease in healing capacity. Treatment with photobiomodulation therapy (PBMT) improves wound healing by inducing increases in mitotic activity, numbers of fibroblasts, collagen synthesis, and neovascularization. Therefore, this study aimed to evaluate the effects of PBMT in cutaneous wound healing in aged rats. A punch biopsy of 8 mm in diameter was performed to produce a skin wound...
July 5, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28676206/manganese-testing-under-a-clean-air-act-test-rule-and-the-application-of-resultant-data-in-risk-assessments
#13
Darcie Smith, George M Woodall, Annie M Jarabek, William K Boyes
In the 1990's, the proposed use of methylcyclopentadienyl manganese tricarbonyl (MMT) as an octane-enhancing gasoline fuel additive led to concerns for potential public health consequences from exposure to manganese (Mn) combustion products in automotive exhaust. After a series of regulatory/legal actions and negotiations, the U.S. Environmental Protection Agency (EPA) issued under Clean Air Act (CAA) section 211(b) an Alternative Tier 2 Test Rule that required development of scientific information intended to help resolve uncertainties in exposure or health risk estimates associated with MMT use...
July 1, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28675665/effects-of-different-rehabilitation-models-on-erythrocyte-deformability-and-nitrite-plus-nitrate-as-end-products-of-nitric-oxide-levels-in-elderly-women
#14
Katarzyna Filar-Mierzwa, Barbara Wójcik, Anna Marchewka, Zbigniew Dąbrowski, Jerzy Superata, Zdzisław Wiśniowski
AIM: The aim of the present study was to analyze the effects of two rehabilitation protocols, dance movement therapy exercises (DMT) and general rehabilitation exercises (GRE), on erythrocyte deformability and plasma levels of nitrite plus nitrate as end products of nitric oxide (NOx) in elderly women. METHODS: The study included 39 women aged 61-82 years, subjected to either GRE (n = 20) or DMT (n = 19). Women were subjected to 5-months programs of GRE and DMT, with each session lasting no longer than 45-50 min, and the intensity of exercising corresponding to no more than 40-60% of heart rate reserve...
July 4, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28670457/hazards-and-health-problems-in-occupations-dominated-by-aged-workers-in-south-korea
#15
Jungsun Park, Soo Geun Kim, Jong-Shik Park, Boyoung Han, Kab Bae Kim, Yangho Kim
BACKGROUND: South Korea's population is aging more rapidly than any other country. Aging of the productive population will lead to shortage of labor and the decreasing quality of the labor force in South Korea. South Korea needs health care strategies to support the establishment of work environments that are appropriate for elderly workers who have reduced physical capacity. This paper aims to identify occupations that are dominated by aged workers and assess the exposure to hazards and work-related health problems of aged workers in these occupations...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28669821/diet-enrichment-with-a-specific-essential-free-amino-acid-mixture-improves-healing-of-undressed-wounds-in-aged-rats
#16
Giovanni Corsetti, Claudia Romano, Evasio Pasini, Emanuele Marzetti, Riccardo Calvani, Anna Picca, Vincenzo Flati, Francesco S Dioguardi
Chronic wounds are a major, often underestimated, health problem for the elderly. Standard wound care products are not usually manufactured to meet the increased demand of nutrients by skin cells in order to regenerate new tissue and accelerate healing. This work was therefore undertaken to establish whether wound healing could be accelerated by nutritional supplementation with a specific mixture tailored to human need of essential amino acids (EAAs) without topical medication. To this end, using a skin full-thickness excisional model in aged rats, we compared the closure dynamics of undressing wounds in animals fed an EAAs-enriched diet or standard diet...
June 29, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28667496/skin-health-connected-to-the-use-of-absorbent-hygiene-products-a-review
#17
REVIEW
Johanna Karlsson Bender, Jan Faergemann, Maria Sköld
Over the past 50 years, absorbent hygiene products such as baby diapers and incontinence products have become essential features of modern day life. Through innovation and enhanced technology, their design, composition and performance have been dramatically upgraded from their early forms, and they have transformed the lives of millions of people, improving their quality of life. Skin health related to the use of absorbent hygiene products has accordingly also greatly improved. Still, the wearing of absorbent hygiene products will affect the skin, and for some users the changes in microclimate, mechanical interactions and the exposure to urine and faeces may result in irritant contact dermatitis, i...
June 30, 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/28664593/clinical-surrogate-markers-for-predicting-metabolic-syndrome-in-middle-aged-and-elderly-chinese
#18
Rui Li, Qi Li, Min Cui, Zegang Yin, Ling Li, Tingting Zhong, Yingchao Huo, Peng Xie
AIMS/INTRODUCTION: This study evaluated the ability of lipid accumulation product (LAP), visceral adiposity index (VAI) and the product of triglycerides and glucose (TyG), three novel markers, in identifying metabolic syndrome (MetS) with different criteria in middle-aged and elderly Chinese. MATERIALS AND METHODS: During June 2012-January 2013, 992 consecutive patients (age≥40 years) were enrolled in Daping Hospital. The criteria of MetS were based on the International Diabetes Federation (IDF) and the modified National Cholesterol Education Program's Adult Treatment Panel III (ATPIII)...
June 30, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28656108/home-features-and-assistive-technology-for-the-home-bound-elderly-in-a-thai-suburban-community-by-applying-the-international-classification-of-functioning-disability-and-health
#19
Supawadee Putthinoi, Suchitporn Lersilp, Nopasit Chakpitak
The ageing population is having an impact worldwide and has created a serious challenge in Thailand's healthcare systems, whereby healthcare practitioners play a major role in promoting independent interaction of their client's abilities, as well as environmental factors. The purpose of this study was to survey features of the home and assistive technology (AT) for the home-bound elderly in the community of Chiang Mai, Thailand. Home evaluation included features inside and outside the home, and AT was based on the International Classification of Functioning, Disability, and Health (ICF) concept...
2017: Journal of Aging Research
https://www.readbyqxmd.com/read/28654954/bioequivalence-between-generic-and-branded-lamotrigine-in-people-with-epilepsy-the-equigen-randomized-clinical-trial
#20
Michel Berg, Timothy E Welty, Barry E Gidal, Francisco J Diaz, Ron Krebill, Jerzy P Szaflarski, Barbara A Dworetzky, John R Pollard, Edmund J Elder, Wenlei Jiang, Xiaohui Jiang, Regina D Switzer, Michael D Privitera
Importance: Switching between generic antiepileptic drugs is a highly debated issue that affects both clinical care and overall health care costs. Objective: To evaluate the single-dose pharmacokinetic bioequivalence of 3 (1 branded and 2 generic drugs) on-market, immediate-release lamotrigine drug products. Design, Setting, and Participants: The Equivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy (EQUIGEN) single-dose study is a crossover, prospective, sequence-randomized, replicate pharmacokinetic study conducted at 5 US academic epilepsy centers...
June 26, 2017: JAMA Neurology
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