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ultrafiltration, aquapheresis, fluid overload

Maria Rosa Costanzo, Daniel Negoianu, Gregg C Fonarow, Brian E Jaski, Bradley A Bart, J Thomas Heywood, Jose L Nabut, Michael P Schollmeyer
BACKGROUND: In patients hospitalized with acutely decompensated heart failure, unresolved signs and symptoms of fluid overload have been consistently associated with poor outcomes. Regardless of dosing and type of administration, intravenous loop diuretics have not reduced heart failure events or mortality in patients with acutely decompensated heart failure. The results of trials comparing intravenous loop diuretics to mechanical fluid removal by isolated venovenous ultrafiltration have yielded conflicting results...
September 2015: American Heart Journal
C Urso, S Brucculeri, G Caimi
WHAT IS KNOWN AND OBJECTIVE: Hyponatraemia, the most common electrolyte imbalance occurring in hospitalized subjects, is usually classified as hypovolaemic, euvolaemic or hypervolaemic. Hyponatraemia is a predictor of death among subjects with chronic heart failure and cirrhosis. The inappropriate secretion of the antidiuretic hormone (AVP) seems to be of pivotal importance in the decline of serum sodium concentration in these clinical conditions. The objective of this review was to summarize recent progress in management of hyponatraemia in SIADH, cirrhosis and heart failure...
August 2015: Journal of Clinical Pharmacy and Therapeutics
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