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Adolescent substance abuse

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https://www.readbyqxmd.com/read/28622813/evaluation-of-drug-use-and-medication-compliance-in-adolescents-admitted-to-a-psychiatric-facility-from-the-pediatric-emergency-department
#1
George Sam Wang, Genie Roosevelt, Amy Becker, Lina Brou, Jeffrey L Galinkin
OBJECTIVES: Knowledge of drug use and medication compliance during mental health evaluation can help guide evaluation and treatment. The objective was to evaluate drug use and medication compliance in a pediatric emergency department (PED) psychiatric population by comparing medical history, standard urine drug screen (EIA), and expanded urine drug screen (HPLC-MS/MS). METHODS: A prospective cohort study of admitted psychiatric patients ≥13years and ≤18years in a tertiary-care children's hospital psychiatric ED from January 31, 2013 through April 16, 2014...
May 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28621645/patterns-and-factors-of-problematic-marijuana-use-in-the-canadian-population-evidence-from-three-cross-sectional-surveys
#2
W I Andrew Bonner, Mustafa Andkhoie, Charlene Thompson, Marwa Farag, Michael Szafron
OBJECTIVES: The objectives of this study are to describe marijuana use in Canada and explore factors associated with problematic use. METHODS: Data from the 2010-2012 circulations of the Canadian Alcohol and Drug Use Monitoring Survey were used to create three logistic regression models for the purposes of identifying and comparing factors associated with the degree of marijuana use, as determined via the WHO Alcohol, Smoking and Substance Abuse Involvement Screening Test (non-problematic, problematic) and European Monitoring Centre for Drugs and Drug Addiction (experiential, recent, current) methods...
June 16, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28610574/predicting-evidence-based-treatment-sustainment-results-from-a-longitudinal-study-of-the-adolescent-community-reinforcement-approach
#3
Sarah B Hunter, Bing Han, Mary E Slaughter, Susan H Godley, Bryan R Garner
BACKGROUND: Implementation support models are increasingly being used to enhance the delivery of evidence-based treatments (EBTs) in routine care settings. Little is known about the extent to which these models lead to continued EBT use after implementation support ends. Moreover, few empirical studies longitudinally examine the hypothesized factors associated with long-term psychosocial EBT use (i.e., sustainment). In an effort to address this gap, the current study examined sustainment of an EBT called the Adolescent-Community Reinforcement Approach (A-CRA) following the end of implementation support...
June 13, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28606210/impulsivity-as-a-mechanism-linking-child-abuse-and-neglect-with-substance-use-in-adolescence-and-adulthood
#4
Assaf Oshri, Steve M Kogan, Josephine A Kwon, K A S Wickrama, Lauren Vanderbroek, Abraham A Palmer, James MacKillop
Emerging developmental perspectives suggest that adverse rearing environments promote neurocognitive adaptations that heighten impulsivity and increase vulnerability to risky behavior. Although studies document links between harsh rearing environments and impulsive behavior on substance use, the developmental hypothesis that impulsivity acts as mechanism linking adverse rearing environments to downstream substance use remains to be investigated. The present study investigated the role of impulsivity in linking child abuse and neglect with adult substance use using data from (a) a longitudinal sample of youth (Study 1, N = 9,421) and (b) a cross-sectional sample of adults (Study 2, N = 1,011)...
June 13, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28605163/associations-of-bullying-and-cyberbullying-with-substance-use-and-sexual-risk-taking-in-young-adults
#5
George Kritsotakis, Maria Papanikolaou, Emmanouil Androulakis, Anastas E Philalithis
PURPOSE: This study aims at identifying the sex-stratified associations of involvement in traditional bullying during middle and high school years and in cyberbullying during college years with multiple health risk behaviors in undergraduate students. DESIGN: This cross-sectional analysis draws on the data of the second wave of the LATO study (Lifestyle & Attitudes in a Student Population) in Greece. METHODS: During November and December 2013, 812 second-year undergraduate students (mean age = 19...
June 12, 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28600961/uplc-ms-ms-assay-for-identification-and-quantification-of-brivaracetam-in-plasma-sample-application-to-pharmacokinetic-study-in-rats
#6
Muzaffar Iqbal, Essam Ezzeldin, Khalid A Al-Rashood
Brivaracetam (BVR) is a novel antiepileptic drug (AED), approved clinically for the treatment of partial onset seizures in adults and adolescents. It has some abuse potential and assigned to Schedule V category under the Controlled Substance Act by the Drug Enforcement Administration. Being an AED and drug of abuse, a sensitive and robust assay is necessary for determination of BVR in biological fluids. Herein, we report a sensitive and validated UPLC-MS/MS assay for identification and quantification of BVR in plasma samples...
June 4, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28599850/tobacco-and-alcohol-use-during-adolescence-interactive-mechanisms-in-animal-models
#7
REVIEW
Yael Abreu-Villaça, Alex C Manhães, Thomas E Krahe, Claudio C Filgueiras, Anderson Ribeiro-Carvalho
There is a strong association between tobacco smoking and the consumption of alcoholic beverages. When compared to the effects of either drug on its own, the combined use may lead to worsened outcomes, such as less successful quitting attempts and increased likelihood of developing mood disorders. Co-consumption most frequently begins during adolescence, a developmental period that is characterized by an increased risk for substance use disorders. However, to date, most studies that have contributed to the current state of knowledge on the mechanisms that underlie tobacco or alcohol use/abuse, and their consequences, adopted adult animal models...
June 6, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28588361/caffeine-and-cannabis-effects-on-vital-neurotransmitters-and-enzymes-in-the-brain-tissue-of-juvenile-experimental-rats
#8
J O Owolabi, S Y Olatunji, A J Olanrewaju
BACKGROUND: Caffeine and cannabis are globally consumed and abused psychoactive substances. While caffeine is legally used in various forms, including in tea and coffee as beverages, it is also consumed in soda and energy drinks as additives. Cannabis, on the other hand, is considered illegal in most countries; albeit, it is being consumed globally particularly by adolescents. PURPOSE: The adolescent stage marks a critical stage of brain development and maturation...
May 2017: Annals of Neurosciences
https://www.readbyqxmd.com/read/28585740/comparing-trauma-exposure-mental-health-needs-and-service-utilization-across-clinical-samples-of-refugee-immigrant-and-u-s-origin-children
#9
Theresa S Betancourt, Elizabeth A Newnham, Dina Birman, Robert Lee, B Heidi Ellis, Christopher M Layne
Most mental health services for trauma-exposed children and adolescents were not originally developed for refugees. Information is needed to help clinicians design services to address the consequences of trauma in refugee populations. We compared trauma exposure, psychological distress, and mental health service utilization among children and adolescents of refugee-origin, immigrant-origin, and U.S.-origin referred for assessment and treatment by U.S. providers in the National Child Traumatic Stress Network (NCTSN)...
June 6, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28584734/teens-engaged-in-collaborative-health-the-feasibility-and-acceptability-of-an-online-skill-building-intervention-for-adolescents-at-risk-for-depression
#10
Emily G Lattie, Joyce Ho, Elizabeth Sargent, Kathryn N Tomasino, J D Smith, C Hendricks Brown, David C Mohr
BACKGROUND: There is an ongoing need for effective and accessible preventive interventions for adolescent depression and substance abuse. This paper reports on a field trial of an online indicated preventive intervention, ProjectTECH, which is based on cognitive-behavioral therapy (CBT) techniques. The study aims to gather information about the feasibility and acceptability of this program. Secondary aims of this study were to examine the impact of the program on depression symptoms, perceived stress, positive affect, and substance use and to compare differences between groups that were led by a peer versus those that were led by a licensed clinician...
June 2017: Internet Interventions: the Application of Information Technology in Mental and Behavioural Health
https://www.readbyqxmd.com/read/28582719/is-adolescent-alcohol-use-associated-with-self-reported-hypomanic-symptoms-in-adulthood-findings-from-a-prospective-birth-cohort
#11
Melissa Fasteau, Daniel Mackay, Daniel J Smith, Thomas D Meyer
High rates of alcohol use disorder (AUD) are reported in people with major depression (MD) and bipolar disorder (BD). Substance abuse problems in adolescence may also indicate risk for future onset of mood disorders, especially BD. Data collected from the Avon Longitudinal Study of Parents and Children (ALSPAC), a large UK birth cohort, allowed information to be collected over several different time points and to test whether problematic alcohol use at age 16 was predictive of vulnerability to hypomanic symptoms at age 23...
May 22, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28582353/effectiveness-of-the-sexual-health-reproductive-health-education-given-to-turkey-adolescents-who-use-alcohol-or-substance
#12
Hacer Ataman, Nuran Kömürcü
OBJECTIVE: The research was conducted experimentally to evaluate the effectiveness of the sexual health/reproductive health (SH/RH) education given to Turkish adolescents who use alcohol or illicit substances. METHODS: The population was adolescents who use alcohol and substances and were inpatients at the Child and Adolescent Substance Addiction Research, Treatment and Education Center. The adolescents were grouped into the following three groups: Group 1 (control group), Group 2 (those who have received training once), and Group 3 (those who have received training twice)...
April 2017: Journal of Addictions Nursing
https://www.readbyqxmd.com/read/28581532/outcome-comorbidity-and-prognosis-in-anorexia-nervosa
#13
REVIEW
Gabriela Jagielska, Iwona Kacperska
Anorexia nervosa (AN) is a relatively common disorder, especially in adolescent and young adult women. The lifetime prevalence of AN in females ranges from 1.2 to 2.2%. The prevalence in males is 10-times lower. The condition is associated with a high risk of chronic course and poor prognosis in terms of treatment and the risk of death. Longer follow-up periods seemed to correspond with increased improvement rates and increased mortality. Onset of the disorder during adolescence is associated with better prognosis...
April 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/28578671/serious-child-and-adolescent-behaviour-disorders-a-valuation-study-by-professionals-youth-and-parents
#14
Karin M Vermeulen, Daniëlle E M C Jansen, Erik Buskens, Erik J Knorth, Sijmen A Reijneveld
BACKGROUND: In child and youth care, quantitative estimates of the impact of serious behaviour problems have not yet been made. Such input is needed to support decision making on investments in treatment. The aim of this paper was to elicit valuations of social and conduct disorders in children and adolescents from three different perspectives: professionals, youth, and parents. METHODS: We obtained valuations from 25 youth care professionals, 50 children (age 9-10) without serious behaviour problems and 36 adolescents (age 16-17) with and without serious behaviour disorders, and 46 parents with children in the aforementioned age categories...
June 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28559549/re-exposure-to-nicotine-associated-context-from-adolescence-enhances-alcohol-intake-in-adulthood
#15
Dor Zipori, Yossi Sadot-Sogrin, Koral Goltseker, Oren Even-Chen, Nofar Rahamim, Ohad Shaham, Segev Barak
Alcohol and nicotine are the two most commonly-abused substances and are often used together. Nicotine enhances alcohol-drinking behaviors in humans and in animals, and was suggested to enhance the reinforcing properties of other reinforcers. Here, we show that nicotine-associated environment, rather than nicotine itself, enhances alcohol intake in rats. Adolescent rats received repeated intermittent injections of nicotine (0.4 mg/kg, i.p., 5 injections, every 3(rd) day) or saline. The injection was paired with their home cage, or with the subsequent alcohol self-administration context...
May 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28559209/short-post-weaning-social-isolation-induces-long-term-changes-in-the-dopaminergic-system-and-increases-susceptibility-to-psychostimulants-in-female-rats
#16
Carine Lampert, Danusa Mar Arcego, Natividade de Sá Couto-Pereira, Aline Dos Santos Vieira, Ana Paula Toniazzo, Rachel Krolow, Emily Garcia, Deusa Aparecida Vendite, Maria Elisa Calcagnotto, Carla Dalmaz
Childhood and adolescence are sensitive periods of development, marked by high brain maturation and plasticity. Exposure to early life stress, such as social isolation, is able to prompt changes in sensitive brain circuitries, essentially in the mesolimbic dopaminergic system and increase the risk for addictive behaviors later in life. Post-weaning social isolation can stimulate the consumption of rewarding substances, like drugs of abuse and palatable foods. However, most studies analyze long periods of social isolation and very little is known about the effects of a brief social isolation in a sensitive period of development and its association with palatable food on the reward system sensitization...
May 27, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28558858/adolescents-from-upper-middle-class-communities-substance-misuse-and-addiction-across-early-adulthood
#17
Suniya S Luthar, Phillip J Small, Lucia Ciciolla
In this prospective study of upper middle class youth, we document frequency of alcohol and drug use, as well as diagnoses of abuse and dependence, during early adulthood. Two cohorts were assessed as high school seniors and then annually across 4 college years (New England Study of Suburban Youth younger cohort [NESSY-Y]), and across ages 23-27 (NESSY older cohort [NESSY-O]; ns = 152 and 183 at final assessments, respectively). Across gender and annual assessments, results showed substantial elevations, relative to norms, for frequency of drunkenness and using marijuana, stimulants, and cocaine...
May 31, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28557547/readiness-to-use-psychoactive-substances-among-second-generation-adolescent-immigrants-and-perceptions-of-parental-immigration-related-trauma
#18
Yael Aviad-Wilchek, Inna Levy, Sarah Ben-David
OBJECTIVES: This research explores the relationship between parental immigration-related trauma and second-generation adolescent substance abuse. To examine this relationship, we focused on Ethiopian adolescents in Israel who are at risk for substance abuse. Many immigrants from Ethiopia experienced severe immigration trauma and research indicates the existence of transgenerational trauma transmission. The current research focuses on the connection between Ethiopian adolescents' perceptions of their parents' immigration trauma and their readiness to use psychoactive substances...
May 30, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28557437/differentiating-physicochemical-properties-between-addictive-and-nonaddictive-adhd-drugs-revealed-by-molecular-dynamics-simulation-studies
#19
Panpan Wang, Xiaoyu Zhang, Tingting Fu, Shuang Li, Bo Li, Weiwei Xue, Xiaojun Yao, Yuzong Chen, Feng Zhu
Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed mental disorder of children and adolescents. Although psychostimulants are currently the first-line drugs for ADHD, their highly addictive profile raises great abuse concerns. It is known that psychostimulants' addictiveness is largely attributed to their interaction with dopamine transporter (DAT) and their binding modes in DAT can thus facilitate the understanding of the mechanism underlining drugs' addictiveness. However, no DAT residue able to discriminate ADHD drugs' addictiveness is identified, and the way how different drug structures affect their abuse liability is still elusive...
June 21, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28544955/associations-of-anxiety-sensitivity-and-emotional-symptoms-with-the-subjective-effects-of-alcohol-cigarettes-and-cannabis-in-adolescents
#20
Raina D Pang, Casey R Guillot, Michael J Zvolensky, Marcel O Bonn-Miller, Adam M Leventhal
Maladaptive emotional traits (anxiety sensitivity [AS], fear of anxiety-related sensations and consequences) and symptoms (major depressive disorder [MDD] and generalized anxiety disorder [GAD] symptoms) could play a role in altering sensitivity to the subjective effects of drugs of abuse in adolescents. Data were drawn from a longitudinal study of high school students in Los Angeles, CA, USA who completed surveys and reported past six-month use of alcohol (n=1054), cigarettes (n=297), or cannabis (n=706). At each of the four semi-annual waves during mid-adolescence (14-16years old), students reported positive and negative subjective drug effects experienced in the prior six-months...
May 18, 2017: Addictive Behaviors
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