Tania C Araujo-Jorge, Maria Teresa Rivera, Jean Vanderpas, Luciana R Garzoni, Anna Cristina C Carvalho, Mariana C Waghabi, Marcelo T Holanda, Mauro F F Mediano, Alejandro M Hasslocher-Moreno, Maria da Gloria Bonecini-Almeida, Roberto M Saraiva, Roberto R Ferreira
For over 60 years, selenium (Se) has been known as an essential microelement to many biological functions, including cardiovascular homeostasis. This review presents a compilation of studies conducted in the past 20 years related to chronic Chagas disease cardiomyopathy (CCC), caused by Trypanosoma cruzi infection, a neglected disease that represents a global burden, especially in Latin America. Experimental and clinical data indicate that Se may be used as a complementary therapy to prevent heart failure and improve heart function...
February 23, 2022: Biomolecules