Roya Mokhtarian, Soodeh Rajabi, Setareh Zahedian, Saeideh Jafarinejad-Farsangi, Morteza Hadizadeh, Masoumeh Sadeghinejad
Breast cancer (BC) is the most prevalent malignancy in women and the second most common disease worldwide, affecting approximately one million individuals annually. Despite the efficacy of conventional chemotherapy, medication resistance and adverse effects limit its effectiveness, leading researchers to explore alternative treatments, including herbal remedies. Saffron, a well-known spice derived from the Crocus sativus L. plant, has shown potential as a BC treatment. The active components of saffron exhibit anti-cancer properties by inducing apoptosis, inhibiting cell division, and modulating signaling pathways implicated in cancer development, such as PI3K/AKT, NF-B, and MAPK...
February 15, 2024: Annales Pharmaceutiques Françaises