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Spasmodic torticollis

Paola Perozzo, Adriana Salatino, Paolo Cerrato, Raffaella Ricci
Mood, anxiety, and other psychological symptoms are common in dystonic patients suffering from blepharospasm (BSP) and spasmodic torticollis (ST). Since sexual well-being is an important aspect of mental health, here, we investigated whether these patients may also experience a worsening of their sexual life. In particular, quality of sexual life was evaluated in patients suffering from BSP (N = 30), ST (N = 30), and in a control group of patient with Hemifacial spasm (HFS; N = 30), undergoing botulinum toxin type A therapy...
2016: Frontiers in Psychology
Tyler Beals, Lawrence Haines
No abstract text is available yet for this article.
August 7, 2016: American Journal of Emergency Medicine
Cécile Delorme, Emmanuel Roze, David Grabli, Jean-Michel Mayer, Bertrand Degos, Marie Vidailhet, Yulia Worbe
BACKGROUND: Abnormalities in the cognitive processing of movement have been demonstrated in patients with dystonia. The sense of agency, which is the experience of initiating and controlling one's own actions, has never before been studied in these patients. OBJECTIVES: We investigated whether the sense of agency is altered in patients with cervical dystonia. METHODS: We used an explicit metacognitive agency task in which participants had to catch targets with a cursor by moving a computer's mouse...
2016: PloS One
Priya Jagota, Lalita Kaewwilai, Nonglak Boonrod, Surat Singmaneesakulchai, Kamolwan Boonpang, Jirada Sringean, Onanong Jitkritsadakul, Sitthi Petchrutchatachart
BACKGROUND: Cervical dystonia (CD) is a debilitating neurological disorder that may gravely affect a patient's quality of life (QoL). Botulinum toxin treatment has been approved as a first-line treatment for this condition. This study aims to look at the efficacy and impact on the QoL of neu-botulinumtoxinA, a newer and cheaper botulinum toxin type A, in patients with CD. METHODS: This is a prospective, open-label, single-arm study. CD patients were recruited and evaluated for severity of CD using the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), and for QoL using the Craniocervical Dystonia Questionnaire (CDQ-24), and the 36-item Short Form Health Survey questionnaire (SF-36) at baseline and 6 weeks after injection...
2016: Tremor and Other Hyperkinetic Movements
Zheng Ding, Song Zhao, Xiangnan Li, Jia Zhao, Dengyan Zhu, Kai Wu
No abstract text is available yet for this article.
June 2016: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
Raquel E Marques, Gonçalo S Duarte, Filipe B Rodrigues, Mafalda Castelão, Joaquim Ferreira, Cristina Sampaio, A Peter Moore, João Costa
BACKGROUND: This is an update of a Cochrane review first published in 2004, and previously updated in 2009 (no change in conclusions). Cervical dystonia is a frequent and disabling disorder characterised by painful involuntary head posturing. Botulinum toxin type A (BtA) is usually considered the first line therapy for this condition, although botulinum toxin type B (BtB) is an alternative option. OBJECTIVES: To compare the efficacy, safety and tolerability of botulinum toxin type B (BtB) versus placebo in people with cervical dystonia...
May 13, 2016: Cochrane Database of Systematic Reviews
Svetlana Tomic, Ivana Petkovic, Tomislav Pucic, Bojan Resan, Stjepan Juric, Tatjana Rotim
Cervical dystonia is focal dystonia characterized by involuntary movement of the neck muscle, which leads to abnormal head posture. It can be accompanied with pain and tremor. In this study, we evaluated the presence of depression and anxiety in patients with cervical dystonia and the influence of dystonia symptoms on the quality of life. Psychiatric symptoms were evaluated by use of the Beck Depression Inventory (BDI-II) and Beck Anxiety Inventory. Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) was used to evaluate the cervical dystonia symptoms...
May 2, 2016: Acta Neurologica Belgica
Cynthia L Comella, Susan H Fox, Kailash P Bhatia, Joel S Perlmutter, Hyder A Jinnah, Mateusz Zurowski, William M McDonald, Laura Marsh, Ami R Rosen, Tracy Waliczek, Laura J Wright, Wendy R Galpern, Glenn T Stebbins
We present the methodology utilized for development and clinimetric testing of the Comprehensive Cervical Dystonia (CD) Rating scale, or CCDRS. The CCDRS includes a revision of the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS-2), a newly developed psychiatric screening tool (TWSTRS-PSYCH), and the previously validated Cervical Dystonia Impact Profile (CDIP-58). For the revision of the TWSTRS, the original TWSTRS was examined by a committee of dystonia experts at a dystonia rating scales workshop organized by the Dystonia Medical Research Foundation...
June 2015: Movement Disorders Clinical Practice
Vitalyy I Tsymbaliuk, Ihor B Tretyak, Mark Yu Freidman, Alexander A Gatskiy
BACKGROUND: The main objective of this study was to analyze the outcomes of denervation and myotomy of the muscles of the omotrapezoid triangle of the neck in the treatment of 58 patients with the laterocollis and torticollis subtypes of spasmodic torticollis. METHODS: Fifty-eight patients with the laterocollis and torticollis subtypes of spasmodic torticollis underwent 135 staged microsurgical denervations, including 25 denervation and myotomy procedures on the dystonic muscles of the omotrapezoid triangle (Tretyak's procedure)...
June 2016: Acta Neurochirurgica
Cynthia L Comella, Joel S Perlmutter, Hyder A Jinnah, Tracy A Waliczek, Ami R Rosen, Wendy R Galpern, Charles A Adler, Richard L Barbano, Stewart A Factor, Christopher G Goetz, Joseph Jankovic, Stephen G Reich, Ramon L Rodriguez, William L Severt, Mateusz Zurowski, Susan H Fox, Glenn T Stebbins
INTRODUCTION: The aim of this study was to test the clinimetric properties of the Comprehensive Cervical Dystonia Rating Scale. This is a modular scale with modifications of the Toronto Western Spasmodic Torticollis Rating Scale (composed of three subscales assessing motor severity, disability, and pain) now referred to as the revised Toronto Western Spasmodic Torticollis Scale-2; a newly developed psychiatric screening instrument; and the Cervical Dystonia Impact Profile-58 as a quality of life measure...
April 2016: Movement Disorders: Official Journal of the Movement Disorder Society
Yi Han, Andrea L Stevens, Khashayar Dashtipour, Robert A Hauser, Zoltan Mari
A systematic pair-wise comparison of all available botulinum toxin serotype A and B treatments for cervical dystonia (CD) was conducted, as direct head-to-head clinical trial comparisons are lacking. Five botulinum toxin products: Dysport(®) (abobotulinumtoxinA), Botox(®) (onabotulinumtoxinA), Xeomin(®) (incobotulinumtoxinA), Prosigne(®) (Chinese botulinum toxin serotype A) and Myobloc(®) (rimabotulinumtoxinB) have demonstrated efficacy for managing CD. A pair-wise efficacy and safety comparison was performed for all toxins based on literature-reported clinical outcomes...
April 2016: Journal of Neurology
P David Charles, Aubrey Manack Adams, Thomas Davis, Kathryn Bradley, Marc Schwartz, Mitchell F Brin, Atul T Patel
BACKGROUND: Pain is a prevailing feature of cervical dystonia (CD), the most common form of focal dystonia. This analysis examined pain relief after onabotulinumtoxinA treatment in CD subjects with moderate/severe pain from the Cervical Dystonia Patient Registry for Observation of OnabotulinumtoxinA Efficacy (CD PROBE). METHODS: CD PROBE was a prospective, multicenter, observational registry of CD subjects who were naïve to botulinum toxin (BoNT), new to physician, or had not received BoNT within ≥ 16 weeks if in a clinical trial...
February 23, 2016: Pain Practice: the Official Journal of World Institute of Pain
Stephen K Allison, Ib R Odderson
Cervical dystonia, also called spasmodic torticollis, is a painful condition in which neck muscles contract involuntarily, and may cause abnormal head position or movements. The primary (or first line of) treatment of cervical dystonia is chemodenervation with injection of botulinum toxin into the affected muscles. We report a case of a young man with idiopathic cervical dystonia who developed anterocollis (forward flexion of the neck) not responsive to prior scalene and sternocleidomastoid muscle injections...
September 2016: Ultrasound Quarterly
Ming-Xiang Zou, Jing Li, Guo-Hua Lv, Xiao-Bin Wang, Bing Wang
No abstract text is available yet for this article.
August 2016: Spine Journal: Official Journal of the North American Spine Society
Sirpa Mustalampi, Jari Ylinen, Katariina Korniloff, Adam Weir, Arja Häkkinen
OBJECTIVE: To evaluate changes in the strength and mechanical properties of neck muscles and disability in patients with cervical dystonia (CD) during a 12-week period following botulinum neurotoxin (BoNT) injections. METHODS: Eight patients with CD volunteered for this prospective clinical cohort study. Patients had received BoNT injections regularly in neck muscles at three-month intervals for several years. Maximal isometric neck strength was measured by a dynamometer, and the mechanical properties of the splenius capitis were evaluated using two myotonometers...
January 2016: Journal of Movement Disorders
Hamza Ayaydın, Hasan Bozkurt
Movement disorders or extrapyramidal symptoms (EPS) associated with selective serotonin reuptake inhibitors (SSRIs) have been reported. Although akathisia was found to be the most common EPS, and fluoxetine was implicated in the majority of the adverse reactions, there were also cases with EPS due to sertraline treatment. We present a child and an adolescent who developed torticollis (cervical dystonia) after using sertraline. To our knowledge, the child case is the first such report of sertraline-induced torticollis, and the adolescent case is the third in the literature...
January 2015: Turkish Journal of Pediatrics
Mengmeng Wang, Shuai Ma, Dianhui Yang
No abstract text is available yet for this article.
August 2015: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Pedro Melo Barbosa, Guilherme Ricciopo Rodrigues, Daniel Sabino de Oliveira, Carolina Pinto de Souza, Vitor Tumas
UNLABELLED: Cervical dystonia is the most frequent type of primary focal dystonia and treatment with botulinum toxin (BTX) is currently the criterion standard. OBJECTIVE: In this study, we compared the safety and efficacy of the following 2 formulations of BTXs available in Brazil: abobotulinumtoxin A (Dysport) and Lanzhou BTX type A (Prosigne), during a follow-up of 13 months. METHODS: We conducted a prospective, randomized, double blind trial with 1 group being treated with Dysport and the other with Prosigne...
November 2015: Clinical Neuropharmacology
Alma Rystedt, Lena Zetterberg, Joachim Burman, Dag Nyholm, Anders Johansson
OBJECTIVES: Intramuscular injections of botulinum toxin (BTX) are used as symptomatic treatment for cervical dystonia. Botox and Dysport are commercial products containing BTX; however, dosage and concentration of the prepared solution vary considerably among studies. The concentration of BTX in the prepared solution affects clinical outcome. This double-blind, randomized crossover trial compares Botox and Dysport in 2 different dose conversion ratios (1:3 and 1:1.7) when diluted to the same concentration (100 U/mL)...
September 2015: Clinical Neuropharmacology
D A Devetiarov, U N Semenova, L I Butiaeva, A S Sedov
Neuronal activity of 50 neurons in nonspecific (Rt, MD) and relay (Voi, Voa) thalamic nuclei was analyzed. Data were obtained by microelectrode technique during 14 stereotactic operations in patients with spasmodic torticollis. Application of Poincare maps and Gap-statistics allowed to reveal 3 main patterns of neuronal activity: irregular single spikes, low-threshold Ca(2+)-dependent rhythmic (3-5 Hz) bursts and combination of bursts and single spikes. In some cases, grouping (in Voi and Rt nuclei) and long burst (in Voa nucleus) patterns were observed...
May 2015: Fiziologiia Cheloveka
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