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https://www.readbyqxmd.com/read/29783262/-analysis-of-final-judgements-in-cases-of-medical-negligence-occurred-in-ukraine
#1
Valentyn V Franchuk, Svitlana V Trach Rosolovska, Petro R Selskyy, Anna Z Mykolenko, Petro Ya Bodnar
OBJECTIVE: Introduction: The peculiarities of the disadvantages of providing medical care in Ukraine are not well-known abroad. The aim: To study the peculiarities of court decisions in cases of unfavorable consequences of medical activity. PATIENTS AND METHODS: Materials and methods: The article analyzes the official data of the General Prosecutor's Office of Ukraine and the website of court decisions regarding criminal cases against medical practitioners. RESULTS: Review: Approximately 600 cases of alleged medical malpractice cases are registered annually in Ukraine...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783240/-effect-of-preventive-treatment-on-cognitive-performance-in-patients-with-multiple-sclerosis
#2
Maria S Shorobura
OBJECTIVE: Introduction: cognitive, emotional and psychopathological changes play a significant role in the clinical picture of multiple sclerosis and influence the effectiveness of drug therapy, working capacity, quality of life, and the process of rehabilitation of patients with multiple sclerosis. The aim: investigate the changes in cognitive function in patients with multiple sclerosis, such as information processing speed and working memory of patients before and after treatment with immunomodulating drug...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783228/awareness-of-pediatric-palliative-care-among-health-care-workers
#3
Oryna Z Detsyk, Zhanna M Zolotarova, Iryna V Stovban, Roman M Melnyk
OBJECTIVE: Introduction: In order to develop such a relatively new type of medical care in Ukraine, as pediatric palliative care, first of all, qualified medical workers are needed. The aim: to assess the awareness of pediatric palliative care among healthcare workers providing medical services to children. PATIENTS AND METHODS: Materials and methods: It was carried out a survey at health facilities of Ivano-Frankivsk region, which provided medical care for children...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783194/quantitative-investigation-of-hydraulic-mixing-energy-input-during-batch-mode-anaerobic-digestion-and-its-impact-on-performance
#4
James McLeod, Z Othman, Rajarathinam Parthasarathy
The relationship between mixing energy input and biogas production was investigated by anaerobically digesting sewage sludge in lab scale, hydraulically mixed, batch mode digesters at six different specific energy inputs. The goal was to identify how mixing energy influenced digestion performance at quantitative levels to help explain the varying results in other published works. The results showed that digester homogeneity was largely uninfluenced by energy input, whereas cumulative biogas production and solids destruction were...
May 18, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29783176/%C3%AF-3-and-folic-acid-act-against-depressive-like-behavior-and-oxidative-damage-in-the-brain-of-rats-subjected-to-early-or-late-life-stress
#5
Gislaine Z Réus, Amanda L Maciel, Helena M Abelaira, Airam B de Moura, Thays G de Souza, Thais R Dos Santos, Ana Caroline Darabas, Murilo Parzianello, Danyela Matos, Mariane Abatti, Ana Carolina Vieira, Vanessa Fucillini, Monique Michels, Felipe Dal-Pizzol, João Quevedo
OBJECTIVES: To investigate the antidepressant and antioxidant effects of omega-3, folic acid and n-acetylcysteine (NAC) in rats which were subjected to early or late life stress. METHODS: Early stress was induced through maternal deprivation (MD), while late life stress was induced using the chronic mild stress (CMS) protocol. Young rats which were subjected to MD and the adult rats which were subjected to CMS were treated with omega-3 fatty acids (0.72 g/kg), NAC (20 mg/kg) or folic acid (50 mg/kg) once/day, for a period of 20 days...
March 30, 2018: Nutrition
https://www.readbyqxmd.com/read/29783169/applying-multi-criteria-analysis-for-preliminary-assessment-of-the-properties-of-alginate-immobilized-myriophyllum-spicatum-in-lake-water-samples
#6
Jelena V Milojković, Jelena B Popović-Djordjević, Lato L Pezo, Ilija D Brčeski, Aleksandar Ž Kostić, Vladan D Milošević, Mirjana D Stojanović
The preliminary assessment of the properties of alginate immobilized aquatic weed Myriophyllum spicatum beads-MsAlg in a multi-element system of nine Serbian lakes water samples was done. Herein, the results obtained in the biosorption experiment with MsAlg contents of twenty-two elements analysed by inductively coupled plasma-optical emission spectrometry, biosorption capacity, element removal efficiency, total hardness (TH) and quality index of water (WQI) are presented. Scanning electron microscopy with energy dispersive X-ray spectroscopy was used for the characterization of M...
May 11, 2018: Water Research
https://www.readbyqxmd.com/read/29782811/the-longitudinal-relationship-between-motor-competence-and-measures-of-fatness-and-fitness-from-childhood-into-adolescence
#7
Rodrigo Antunes Lima, Anna Bugge, Annette K Ersbøll, David F Stodden, Lars B Andersen
OBJECTIVES: To examine longitudinal (seven years) relationships among cardiorespiratory fitness (VO2peak ), body fatness, and motor competence. METHOD: Data were collected as part of the Copenhagen School Child Intervention Study (CoSCIS). Body fatness was assessed by the sum of four skinfolds. VO2peak was measured directly in a continuous running protocol. Motor competence was assessed using the Körperkoordinationtest für Kinder. This study used multilevel linear mixed models to evaluate the reciprocal longitudinal association between body fatness, VO2peak , and motor competence...
May 18, 2018: Jornal de Pediatria
https://www.readbyqxmd.com/read/29782648/patient-preferences-for-topical-treatment-of-actinic-keratoses-a-discrete-choice-experiment
#8
D Kopasker, A Kwiatkowski, R N Matin, C A Harwood, F Ismail, J T Lear, J Thomson, Z Hasan, G N Wali, A Milligan, L Crawford, I Ahmed, H Duffy, C M Proby, P F Allanson
BACKGROUND: Treatment of actinic keratoses (AK) is a potentially effective strategy for prevention of cutaneous squamous cell carcinoma (cSCC). However, the patient perspective on potential benefits of AK treatment in terms of skin cancer reduction has received little attention to date. OBJECTIVES: (1) To investigate patient preferences for AK topical treatments using a discrete choice experiment (DCE); (2) To evaluate patient willingness to trade between clinical benefit and medical burden...
May 21, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29782581/correction-to-cbfa2t2-is-associated-with-a-cancer-stem-cell-state-in-renal-cell-carcinoma
#9
Du-Chu Chen, You-De Liang, Liang Peng, Yi-Ze Wang, Chun-Zhi Ai, Xin-Xing Zhu, Ya-Wei Yan, Yasmeen Saeed, Bin Yu, Jingying Huang, Yuxin Gao, Jiaqi Liu, Yi-Zhou Jiang, Min Liu, Demeng Chen
[This corrects the article DOI: 10.1186/s12935-017-0473-z.].
2018: Cancer Cell International
https://www.readbyqxmd.com/read/29782466/mucin-expression-in-colorectal-cancer-crc-systematic-review-and-meta-analysis
#10
Yaron Niv, Theodore Rokkas
BACKGROUND: A body of evidence has suggested that mucins play an important role in adhesion, invasion, and cancer metastasis. However, this evidence is scarce and sometimes confusing. OBJECTIVE: We performed a systematic review and meta-analysis of available studies to better define the role of mucins in the behavior of colorectal cancer (CRC). METHODS: Medical literature was searched through November 30, 2017, using suitable keywords. Pooled estimates, that is, odd ratios (ORs), were obtained using fixed or random-effects models, as appropriate...
May 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29782389/development-of-a-novel-self-administered-cognitive-assessment-tool-and-normative-data-for-older-adults
#11
Raphael J Monsch, Amélie C Burckhardt, Manfred Berres, Alessandra E Thomann, Michael M Ehrensperger, Luzius A Steiner, Nicolai Goettel
BACKGROUND: Preexisting cognitive impairment in surgical patients is one of the leading risk factors for adverse cognitive outcomes such as postoperative delirium and postoperative cognitive dysfunction. We developed a self-administered tablet computer application intended to assess the individual risk for adverse postoperative cognitive outcomes. This cross-sectional study aimed to establish normative data for the tool. MATERIALS AND METHODS: Healthy volunteers aged 65 years and above were administered the Mini-Mental State Examination, Geriatric Depression Scale, and Consortium to Establish a Registry for Alzheimer's Disease-Neuropsychological Assessment Battery to assess cognitive health...
May 18, 2018: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/29782289/-the-effect-of-changing-of-conventional-antihypertensive-therapy-to-a-triple-fixed-combination-therapy-with-rosuvastatin-in-high-cardiovascular-risk-patients
#12
F T Ageev, Z N Blankova, N S Samsonova
BACKGROUND: The low efficiency of recommended therapy for reducing cardiovascular risk (CV) in patients with arterial hypertension even with an effective blood pressure decrease is often due to the persistence of high blood cholesterol and arterial stiffness. Among the effective ways to achieve the goal of therapy is considered the changing to a single-pill combinations (SPCs) of two antihypertensive drugs and statin. AIM: To assess influence of fixed combination consisted of amlodipine, lisinopril and rosuvastatin to the dynamic of lipid spectrum, blood pressure level and elastic properties of arteries in patients with arterial hypertension and high risk of cardio-vascular complications being transferred from their preceding antihypertensive therapy...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29782286/-ngal-as-a-marker-for-some-extrarenal-complications-in-acute-coronary-syndrome
#13
M A Shalenkova, Z D Mikhailova, P F Klimkin
AIM: To study the role of neutrophil gelatinase-associated lipocalin (NGAL) as a marker for extrarenal complications in patients with acute coronary syndrome (ACS). MATERIALS AND METHODS: For 110 patients with ACS on days 1-3 of hospitalization, concentrations of NGAL, serum (s-NGAL) and urinary (u-NGAL) NGAL, and N-terminal fragment of pro-B natriuretic peptide (NT-proBNP) were measured, and transthoracic echocardiography was performed. Incidence of cardiovascular complications was determined during the stay in the hospital; hemodynamic parameters (systolic and diastolic blood pressure, heart rate) were measured on admission...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29782272/-duration-and-timing-of-initiation-of-therapy-with-platelet-p2y12-inhibitors-in-the-treatment-of-patients-with-acute-coronary-syndrome
#14
S V SHalaev, Z M Safiullina
In recent years, the issues of choice of an agent for dual antiplatelet therapy (DAPT) as well as timing of initiation and duration of DAPT in patients with acute coronary syndrome (ACS) have been actively discussed. In this article we present data of major randomized trials of clopidogrel and novel P2Y12 inhibitors - prasugrel, ticagrelor, cangrelor - assessing strategy of administration of antiaggregants in patients with ACS before coronary angiography / percutaneous coronary intervention. The article also contains analysis of differences between recommendations of the European Society of Cardiology and American College of Cardiology/American Heart Association on therapy with oral P2Y12 inhibitors in the management of patients with ACS...
March 2018: Kardiologiia
https://www.readbyqxmd.com/read/29782259/-relationship-of-remodeling-of-carotid-arteries-and-left-ventricular-geometry-in-patients-with-chronic-glomerulonephritis
#15
I T Murkamilov, K A Aitbaev, A S Sarybaev, V V Fomin, I G Gordeev, Z R Rayimzhanov, N A Redjapova, F A Yusupov
PURPOSE: to study clinical-functional features of remodeling of carotid arteries and its relation to restructuring of the left ventricle (LV) in patients with chronic glomerulonephritis at pre-dialysis stage. MATERIALS AND METHODS: We examined 269 patients (189 men, 80 women) with chronic glomerulonephritis (CGN) aged 17-71 years, at pre-dialysis stages of the disease. We analyzed biochemical parameters of peripheral blood with the determination of daily proteinuria and glomerular filtration rate (GFR)...
April 2018: Kardiologiia
https://www.readbyqxmd.com/read/29782257/-deficit-of-magnesium-and-states-of-hypercoagulation-intellectual-analysis-of-data-obtained-from-a-sample-of-patients-aged-18-50-years-from-medical-and-preventive-facilities-in-russia
#16
O A Gromova, I Y Torshin, Z D Kobalava, M A Sorokina, S V Villevalde, S A Galochkin, I V Gogoleva, O N Gracheva, T R Grishina, A N Gromov, E Y Egorova, A G Kalacheva, S I Malyavskaya, I A Meraĭ, V A Semenov
The states characterized by pronounced hypercoagulable components (deep vein thrombosis, cardio- and cerebro-vascular pathologies) are caused by multiple pathophysiological factors, including insufficient supply of magnesium (Mg) and other micronutrients. AIM: to present results of analysis of the Institute of Microelements Data Base (IMDB) performed from point of view of interrelationships of Mg deficit and hypercoagulable states in adults treated in medico-preventive facilities of Central, Northwestern, Northern, and Siberian federal districts of Russia...
April 2018: Kardiologiia
https://www.readbyqxmd.com/read/29782255/-high-on-treatment-platelet-reactivity-determinants-on-dual-antiplatelet-therapy-in-patients-with-ischemic-heart-disease-before-elective-percutaneous-coronary-intervention
#17
E Z Golukhova, M V Grigoryan, M N Ryabinina, N I Bulaeva
OBJECTIVE: to determine impact of different laboratory and genetic factors on high on-treatment platelet reactivity (HOPR) during dual antiplatelet therapy (DAPT). METHODS: We included in this study 94 patients with stable ischemic heart disease (mean age 59±9.67 years). All patients underwent elective PCI with implantation of drug eluting stents at the background of dual antiplatelet therapy (DAPT) with aspirin and clopidogrel. Platelet reactivity was assessed using light transmission aggregometry with 5 μmol/L ADP (LTA 5ADP) and VerifyNow assay before PCI...
April 2018: Kardiologiia
https://www.readbyqxmd.com/read/29782252/-problems-of-anticoagulation-therapy-in-patients-with-chronic-heart-failure-and-atrial-fibrillation-role-of-rivaroxaban
#18
Z D Kobalava, S V Villevalde, E A Troitskaya
Heart failure and atrial fibrillation are the two new epidemics of cardiovascular disease. Their frequent coincidence increases mortality rates mainly because of increased risk of thromboembolic events. The review focuses on epidemiology, mechanisms, prognosis in patients with heart failure and atrial fibrillation, approaches to the administration of direct oral anticoagulants and role of rivaroxaban.
2018: Kardiologiia
https://www.readbyqxmd.com/read/29782035/simultaneous-quantitation-of-rosuvastatin-and-ezetimibe-in-human-plasma-by-lc-ms-ms-pharmacokinetic-study-of-fixed-dose-formulation-and-separate-tablets
#19
Abhaysingh Bhadoriya, Mallika Sanyal, Priyanka A Shah, Pranav S Shrivastav
A simple, high-throughput and highly sensitive liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method has been developed for the simultaneous estimation of rosuvastatin and free ezetimibe. Liquid-liquid extraction was carried out using methyl-tert butyl ether after prior acidification from 300 μL human plasma. The recovery for both the analytes and their deuterated internal standards (ISs) ranged from 95.7-99.8 %. Rosuvastatin and ezetimibe were separated on Symmetry C18 column using acetonitrile and ammonium formate buffer, pH 3...
May 21, 2018: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29781987/retrospective-microrna-sequencing-complementary-dna-library-preparation-protocol-using-formalin-fixed-paraffin-embedded-rna-specimens
#20
Olivier Loudig, Christina Liu, Thomas Rohan, Iddo Z Ben-Dov
-Archived, clinically classified formalin-fixed paraffin-embedded (FFPE) tissues can provide nucleic acids for retrospective molecular studies of cancer development. By using non-invasive or pre-malignant lesions from patients who later develop invasive disease, gene expression analyses may help identify early molecular alterations that predispose to cancer risk. It has been well described that nucleic acids recovered from FFPE tissues have undergone severe physical damage and chemical modifications, which make their analysis difficult and generally requires adapted assays...
May 5, 2018: Journal of Visualized Experiments: JoVE
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