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renal kidney stones aki ckd sodium

J Bradley Layton, Philip J Klemmer, Christian F Christiansen, Andrew S Bomback, John A Baron, Robert S Sandler, Abhijit V Kshirsagar
BACKGROUND & AIMS: Oral sodium phosphate (OSP) is a common bowel purgative administered before colonoscopy; the Food and Drug Administration has warned against its use because of concerns about acute kidney injury (AKI) from the absorbed phosphate and dystrophic calcification. However, it is not clear if OSP is associated with AKI in the general population or in high-risk subgroups undergoing colonoscopy. We estimated the risk of AKI among patients undergoing a screening colonoscopy using OSP vs polyethylene glycol (PEG) for bowel cleansing in a large, US-based claims database...
September 2014: Clinical Gastroenterology and Hepatology
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