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Urgency urinary incontinence

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https://www.readbyqxmd.com/read/28227825/real-time-autonomous-bladder-event-classification-and-closed-loop-control-from-single-channel-pressure-data
#1
Robert Karam, Swarup Bhunia, Steve Majerus, Steven W Brose, Margot S Damaser, Dennis Bourbeau, Robert Karam, Swarup Bhunia, Steve Majerus, Steven W Brose, Margot S Damaser, Dennis Bourbeau, Steve Majerus, Margot S Damaser, Robert Karam, Steven W Brose, Dennis Bourbeau, Swarup Bhunia
Urinary incontinence, or the loss of bladder control, is a debilitating condition affecting millions worldwide, which significantly reduces quality of life. Neuromodulation of lower urinary tract nerves can be used to treat sensations of urgency in many subjects, including those with Spinal Cord Injury (SCI). Event driven, or conditional stimulation has been investigated as a possible improvement to the state-of-the-art open-loop stimulation systems available today. However, this requires a robust, adaptive, and noise-tolerant method of classifying bladder function from real-time bladder pressure measurements...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225655/mnte-2-pyp-treatment-or-nox4-inhibition-protects-against-radiation-induced-damage-in-mouse-primary-prostate-fibroblasts-by-inhibiting-the-tgf-beta-1-signaling-pathway
#2
Arpita Chatterjee, Elizabeth A Kosmacek, Rebecca E Oberley-Deegan
Prostate cancer patients who undergo radiotherapy frequently suffer from side effects caused by radiation-induced damage to normal tissues adjacent to the tumor. Exposure of these normal cells during radiation treatment can result in tissue fibrosis and cellular senescence, which ultimately leads to postirradiation-related chronic complications including urinary urgency and frequency, erectile dysfunction, urethral stricture and incontinence. Radiation-induced reactive oxygen species (ROS) have been reported as the most potent causative factor for radiation damage to normal tissue...
February 22, 2017: Radiation Research
https://www.readbyqxmd.com/read/28217699/the-female-urinary-microbiota-urinary-health-and-common-urinary-disorders
#3
REVIEW
Linda Brubaker, Alan J Wolfe
This review provides the clinical context and updated information regarding the female urinary microbiota (FUM), a resident microbial community within the female bladder of many adult women. Microbial communities have variability and distinct characteristics in health, as well as during community disruption (dysbiosis). Information concerning characteristics of the FUM in health and disease is emerging. Sufficient data confirms that the microbes that compose the FUM are not contaminants and are cultivatable under appropriate conditions...
January 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28213799/the-hybrid-technique-of-pelvic-organ-prolapse-treatment-apical-sling-and-subfascial-colporrhaphy
#4
Dmitry Shkarupa, Nikita Kubin, Alexey Pisarev, Anastasiya Zaytseva, Ekaterina Shapovalova
INTRODUCTION AND HYPOTHESIS: The majority of patients with cystocele undergoing reconstructive surgery have combined defects of pubocervical fascia and uterosacral/cardinal ligament complex. In this regard, the simultaneous correction of both defects is rational. Furthermore, decreasing the use of synthetic materials in pelvic floor surgery is an important goal. The aim was to evaluate the objective and subjective cure rate of a hybrid technique: bilateral sacrospinous fixation using modern monofilament synthetic tape (apical sling) combined with the original technique of subfascial colporrhaphy...
February 17, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28197002/an-exploratory-study-for-bladder-dysfunction-in-atypical-antipsychotic-emergent-urinary-incontinence
#5
Preeti Sinha, Anupam Gupta, V Senthil Kumar Reddi, Chittaranjan Andrade
INTRODUCTION: This is an exploratory study, which aimed to analyze urodynamic findings in patients who are on atypical antipsychotics and present with urinary incontinence (UI) in order to understand the mechanisms of antipsychotic-emergent UI. PATIENTS AND METHODS: Eight patients (34 ± 7.6 years; five males and three females) diagnosed with schizophrenia or other psychotic disorders, who were on risperidone, olanzapine, or clozapine monotherapy and having UI were recruited...
October 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28194560/a-comparative-study-of-electroacupuncture-at-zhongliao-bl33-and-other-acupoints-for-overactive-bladder-symptoms
#6
Likun Yang, Yang Wang, Qian Mo, Zhishun Liu
Electroacupuncture (EA) at Zhongliao (BL33) can improve the symptoms of overactive bladder (OAB), such as urinary frequency, urgency, and incontinence. However, its performance compared with other acupoints remains unclear. This study investigated the effects of EA at BL33 with deep needling on rats with OAB by detecting urodynamics in eight groups: no intervention group, D-BL33 group (deep needling at BL33), S-BL33 group (shallow needling at BL33), non-acupoint group (needling at the non-acupoint next to BL33), Weizhong (BL40) group, Sanyinjiao (SP6) group, Tongtian (BL7) group, and Hegu (LI4) group...
February 14, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28192077/impact-of-age-and-comorbidities-on-utilization-of-sacral-neuromodulation
#7
Anna Er Faris, Bradley C Gill, Javier Pizarro-Berdichevsky, Elodi Dielubanza, Marisa M Clifton, Henry Okafor, Howard B Goldman, Courtenay K Moore, Raymond R Rackley, Sandip P Vasavada
PURPOSE: To investigate the influence of patient age on sacral nerve stimulation(SNS) trial outcomes, device implantation, and treatment durability. MATERIALS AND METHODS: A database of all SNS procedures between 2012-2014 at a high-volume institution was analyzed for associations of age with SNS indication, trial stimulation success, device revision, and device explantation. RESULTS: Within a 356 patient cohort, non-obstructive urinary retention and urgency- frequency patients were younger than those with urgency urinary incontinence...
February 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28190530/prevalence-and-characteristics-of-urinary-incontinence-in-a-cohort-of%C3%A2-patients-with-chronic-heart-failure
#8
Kerry Poole, Monica Kerlin, Rochelle Wynne
BACKGROUND: Evidence describing the characteristics of urinary incontinence (UI) in patients with chronic heart failure (CHF), and the impact of this combination of conditions on functional status and quality of life, is limited. OBJECTIVE: The primary aim of this study was to determine the prevalence and characteristics of UI in a cohort of CHF patients. METHODS: A prospective survey of 100 outpatients with CHF was undertaken. RESULTS: There were 43 (65...
February 9, 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28185313/improvement-in-lower-urinary-tract-symptoms-across-multiple-domains-following-ventriculoperitoneal-shunting-for-idiopathic-normal-pressure-hydrocephalus
#9
Sarah C Krzastek, Samuel P Robinson, Harold F Young, Adam P Klausner
AIMS: The purpose of this study was to evaluate the change in lower urinary tract symptoms following ventriculoperitoneal shunting in patients with idiopathic normal pressure hydrocephalus (iNPH). METHODS: Lower urinary tract symptoms in patients with new-onset iNPH were prospectively evaluated using validated questionnaires from the International Consultation on Incontinence to assess overactive bladder (ICIq-OAB), incontinence (ICIq-UI), and quality of life (ICIq-LUTqol), as well as the American Urological Association Symptom Score bother scale, prior to and following ventriculoperitoneal shunting for iNPH...
February 10, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28169449/a-questionnaire-survey-to-assess-lower-urinary-tract-symptoms-in-patients-with-chronic-stroke
#10
Minoru Miyazato, Takeshi Tana, Akira Higa, Kiyoshi Wakugami, Takashi Tokashiki, Hirokuni Sakima, Aiwa Maehara, Asuka Ashikari, Takuma Oshiro, Yusuke Ohya, Seiichi Saito
OBJECTIVES: In this study, we evaluated the prevalence of lower urinary tract symptoms and the associated clinical features in patients with chronic stroke. METHODS: Patients with stroke who had been regularly followed up at general medical hospitals in Okinawa, Japan were enrolled in the study. The patients were asked to complete a self-reported questionnaire regarding their physical activity, medical history, and the core lower urinary tract symptom score (CLSS) questionnaire, with anonymity...
February 7, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28161378/right-sided-interstim-placement-in-a-patient-with-left-sacral-hypoplasia
#11
Laura Horodyski, Ayman Mahdy
Sacral hypoplasia is a rare anomaly and the least severe pattern of caudal regression syndrome as described by the Renshaw classification system. These patients may suffer from bladder or bowel dysfunction. Here, we present a successful case of right InterStim placement for the treatment of refractory urinary urgency, frequency, and urinary incontinence in a patient with left sacral hypoplasia.
February 1, 2017: Urology
https://www.readbyqxmd.com/read/28160010/the-effect-of-sacral-neuromodulation-on-pregnancy-a-systematic-review
#12
Amr Mahran, Alex Soriano, Ahmed S Safwat, Adonis Hijaz, Sangeeta T Mahajan, Emanuel C Trabuco, Steven W Siegel, Sherif A El-Nashar
INTRODUCTION AND HYPOTHESIS: To evaluate the effects of sacral neuromodulation (SNM) on pregnancy and the impact of delivery on SNM function. METHODS: A systematic search was conducted through January 2016. We selected studies including women who had SNM and a subsequent pregnancy. RESULTS: Out of 2,316, eight studies were included, comprising 22 patients (26 pregnancies). SNM indications were Fowler's syndrome in 11, urinary retention in 6, fecal incontinence in 1, fecal and urinary urgency in 1, overactive bladder in 1, intractable interstitial cystitis in 1, and myelodysplasia in 1...
February 3, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28153510/efficacy-of-electrical-pudendal-nerve-stimulation-versus-transvaginal-electrical-stimulation-in-treating-female-idiopathic-urgency-urinary-incontinence
#13
Siyou Wang, Jianwei Lv, Xiaoming Feng, Tingting Lv
PURPOSE: To compare the efficacies of electrical pudendal nerve stimulation (EPNS) versus transvaginal electrical stimulation (TES) in treating female idiopathic urgency urinary incontinence (UUI). MATERIALS AND METHODS: One hundred and twenty female patients with idiopathic urgency urinary incontinence (UUI) refractory to medication were randomized, at a ratio of 2:1, into groupⅠof 80 cases and groupⅡof 40 cases. GroupsⅠandⅡwere treated by EPNS and transvaginal electrical stimulation (TES), respectively...
January 30, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28149080/urodynamic-profile-in-acute-transverse-myelitis-patients-its-correlation-with-neurological-outcome
#14
Anupam Gupta, Sushruth Nagesh Kumar, Arun B Taly
OBJECTIVE: The objective of this study was to observe urodynamic profile of acute transverse myelitis (ATM) patients and its correlation with neurological outcome. PATIENTS AND METHODS: This prospective study was conducted in the neurorehabilitation unit of a tertiary university research hospital from July 2012 to June 2014. Forty-three patients (19 men) with ATM with bladder dysfunction, admitted in the rehabilitation unit, were included in this study. Urodynamic study (UDS) was performed in all the patients...
January 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28139859/long-term-effect-of-conservative-treatment-versus-low-threshold-endoscopic-desobstruction-on-urine-incontinence-and-urgency-in-boys-with-persistent-overactive-bladder-symptoms-a-cohort-study
#15
Pauline M L Hennus, Joop van den Hoek, Arno W Hoes, Rolf H H Groenwold, J L Ruud Bosch, Tom P V M de Jong, Laetitia M O de Kort
AIMS: To assess the long-term effects of two treatment strategies (low threshold endoscopic desobstruction vs. conservative treatment) on urinary incontinence (UI) and urgency-frequency in boys. METHODS: Boys with persistent overactive bladder symptoms treated in two tertiary referral centers between 2006 and 2009 were included. Treatment strategy in center 1 was urethrocystoscopy (UCS) and in case of obstruction urethral desobstruction and in center 2 conservative...
January 31, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28120450/an-investigation-of-lower-urinary-tract-symptoms-in-women-aged-40-and-over
#16
Neziha Sever, Umran Oskay
OBJECTIVE: The objective of this study was to determine lower urinary tract symptoms (LUTS) and associated risk factors in women aged 40 years and over. METHODS: The study was carried out with a total of 312 women. The data were collected between 1 January 2009 and 30 July 2010. As research instruments, an interview form of 19 questions that questioned personal characteristics and was developed by researchers, and the Bristol Female Lower Urinary Tract Symptoms (BFLUTS) Questionnaire evaluating lower urinary tract symptoms were used...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28120448/the-long-term-outcomes-of-the-tension-free-vaginal-tape-procedure-for-treatment-of-female-stress-urinary-incontinence-data-from-minimum-13%C3%A2-years-of-follow-up
#17
Phil Hyun Song, Dae Hyeon Kwon, Young Hwii Ko, Hee Chang Jung
OBJECTIVES: To evaluate the long-term outcomes from the tension-free vaginal tape (TVT) procedure, we investigated the data from a minimum 13-year follow-up and predictive risk factors affecting efficacy for treatment of female stress urinary incontinence (SUI). METHODS: A total of 206 (mean age, 59.2 ± 8.8 years) women who underwent the TVT procedure for SUI were selected and followed up for at least 13 years (mean, 162.4 months; range, 156-174) after TVT procedure...
January 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28118213/a-case-report-subanesthetic-ketamine-infusion-for-treatment-of-cancer-related-pain-produces-urinary-urge-incontinence
#18
Barbara A Vickers, Wayne Lee, Joann Hunsberger
Oncology patients undergoing treatment can experience substantial pain related to their disease or prescribed therapy. Ketamine infusions at subanesthetic doses have been used at our institution to supplement the pain management regimens of 262 patients. We present 2 cases in which young adult patients being treated with subanesthetic ketamine for cancer-related pain experienced urinary urgency and incontinence after initiation or increase of the ketamine infusion. This adverse effect has not been reported previously at this dosing range...
January 23, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28118174/modifiers-of-response-to-treatment-with-fesoterodine-for-urgency-predominant-urinary-incontinence-in-a-randomized-controlled-trial
#19
William D Winkelman, Alison J Huang, Michael Schembri, Rebecca G Rogers, Holly Richter, Deborah L Myers, Stephen R Kraus, Karen C Johnson, Rachel Hess, Tomas Gregory, Catherine S Bradley, Lily Arya, Janette S Brown, Leslee L Subak
OBJECTIVE: The aim of this study was to identify clinical and demographic characteristics that moderate response to treatment with fesoterodine among women with a diagnosis of urgency-predominant urinary incontinence. METHODS: A multicenter, double-blinded, 12-week randomized controlled trial of pharmacologic therapy for urgency-predominant urinary incontinence in community-dwelling women diagnosed by the 3-item Incontinence Questionnaire (3IQ) was previously performed...
January 24, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28116468/patient-reported-lower-urinary-tract-symptoms-after-hysterectomy-or-hysteroscopy-a-study-from-the-swedish-quality-register-for-gynecological-surgery
#20
Mathias Pålsson, Jan-Henrik Stjerndahl, Gabriel Granåsen, Mats Löfgren, Karin Sundfeldt
INTRODUCTION AND HYPOTHESIS: Hysterectomy is sometimes considered the cause of lower urinary tract symptoms (LUTS). We hypothesized that hysterectomy for abnormal uterine bleeding and/or symptoms of fibroids is more likely to cause LUTS than a hysteroscopic procedure for the same indications. METHODS: Two groups of women were compared: one group comprised 3,618 women who had had a hysterectomy due to abnormal uterine bleeding or symptoms of fibroids and the other group comprised 238 women who had had hysteroscopic treatment for the same indications...
January 23, 2017: International Urogynecology Journal
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