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Urgency urinary incontinence

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https://www.readbyqxmd.com/read/29329897/-botulinium-toxin-and-idiopathic-overactive-bladder-multicentric-contempory-management-in-bourgogne
#1
A Schneider, B Tourlonias, L Cormier, E Mourey, N Koutlidis, E Delorme, J Pasquale, I Kermarec, A-D Foahom-Kamwa, V Bonniaud
INTRODUCTION: Since 2014, OnabotulinumtoxinA Botox® (Allergan, Inc., Irvine, USA) represents a new therapeutic option for second-line treatment of idiopathic overactive bladder. The purpose of the current study was to evaluate practices of surgeons using onabotulinium toxin (BoNTA) in this indication. MATERIAL AND METHODS: All urogynecology centers of the country were asked in order to list all patients who were treated since marketing autorisation. Patient symptoms, previous treatments, paraclinic evaluations, data of surgery and the characteristics of the follow up were collected and analyzed...
January 9, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29324595/association-of-pharmacologic-treatment-of-urgency-urinary-incontinence-with-sleep-quality-and-daytime-sleepiness
#2
Qurratul A Warsi, Alison J Huang, Rachel Hess, Lily A Arya, Holly E Richter, Catherine S Bradley, Rebecca G Rogers, Deborah L Myers, Karen C Johnson, William D Winkelman, W Thomas Gregory, Stephen R Kraus, Michael Schembri, Jeanette S Brown, Katie L Stone, Leslee L Subak
OBJECTIVE: To evaluate the association between pharmacologic therapy for urgency urinary incontinence (UUI) and sleep quality. METHODS: We conducted a planned secondary data analysis of sleep outcomes in a previously conducted multicenter, double-blind, 12-week randomized trial of pharmacologic therapy for urgency-predominant incontinence among community-dwelling women self-diagnosed using the 3-Incontinence Questions questionnaire. Participants (N=645) were assigned randomly to 4-8 mg antimuscarinic therapy daily or placebo...
January 9, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29315998/effectiveness-and-quality-of-life-10%C3%A2-years-after-transobturator-suburethral-tape-surgery-for-stress-urinary-incontinence
#3
Paula Celada, Patricia Cañete, Ester Ortiz Murillo, Juan J Tarín, Antonio Cano
AIM: We aimed to measure the effectiveness and quality of life (QoL) 10 years after transobturator suburethral tape surgery. METHODS: We carried out a prospective observational study of 42 women assessed 10 years after surgical intervention with the transobturator technique. The main outcome measures were subjective and objective cure or improvement, complications, and changes in QoL. RESULTS: The median abdominal leak point pressure had been 92 (82-113) mL H2 O prior to surgery...
January 5, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29305250/diagnosis-and-treatment-of-urinary-tract-infections-across-age-groups
#4
REVIEW
Christine M Chu, Jerry L Lowder
Urinary tract infections (UTI) are the most common outpatient infections, but predicting the probability of UTI through symptoms and test results can be complex. The most diagnostic symptoms of UTI include change in frequency, dysuria, urgency, and presence or absence of vaginal discharge, but UTIs may present differently in older women. Dipstick urinalysis is popular for its availability and usefulness, but results must be interpreted in context of the patient's pretest probability based on symptoms and characteristics...
January 2, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29300259/sleep-quality-and-daytime-sleepiness-among-women-with-urgency-predominant-urinary-incontinence
#5
William D Winkelman, Ann Warsi, Alison J Huang, Michael Schembri, Rebecca G Rogers, Holly E Richter, Deborah L Myers, Stephen R Kraus, Karen C Johnson, Rachel Hess, Thomas Gregory, Catherine S Bradley, Lily A Arya, Jeanette S Brown, Katie L Stone, Leslee L Subak
OBJECTIVE: The objective of this study was to examine the strength and direction of the association between urinary symptoms and both poor quality sleep and daytime sleepiness among women with urgency urinary incontinence. METHODS: A planned secondary analysis of baseline characteristics of participants in a multicenter, double-blinded, 12-week randomized controlled trial of pharmacologic therapy for urgency-predominant urinary incontinence in ambulatory women self-diagnosed by the 3 Incontinence Questions was performed...
January 3, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29260636/effective-treatment-of-neurogenic-detrusor-overactivity-in-multiple-sclerosis-patients-using-desmopressin-and-mirabegron
#6
Athanasios Zachariou, Maria Filiponi, Dimitrios Baltogiannis, John Giannakis, Fotios Dimitriadis, Panagiota Tsounapi, Atsushi Takenaka, Nikolaos Sofikitis
INTRODUCTION: Multiple sclerosis (MS) is the commonest progressive neurological disease affecting young people. With advancing disease, management of neurogenic detrusor overactivity (NDO) based on antimuscarinics may prove inadequate and if based on botulinum toxin, may necessitate clean intermittent self-catheterization. The aim of the study was to evaluate the effectiveness of combined mirabegron and desmopressin administration in the treatment of NDO in patients with MS. MATERIALS AND METHODS: Sixty patients diagnosed with MS and NDO were evaluated...
December 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29248808/mixed-urinary-incontinence-a-prospective-study-on-the-effect-of-trans-obturator-mid-urethral-sling
#7
Franca Natale, Ester Illiano, Chiara La Penna, Raffaele Balsamo, Elisabetta Costantini
OBJECTIVES: It is hypothesized that urethral dysfunction is central in mixed urinary incontinence (MUI) in women, since urine entering the proximal urethra under increased intra-abdominal pressure provokes a urethro-detrusorial reflex and involuntary detrusor contraction. Mid-urethral slings have been proposed as a solution. Our primary objective was to evaluate the long-term subjective and objective outcomes on continence and other urinary symptoms of a trans-obturator mid-urethral sling (TOT) procedure...
December 6, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29241925/a-community-based-epidemiological-survey-of-overactive-bladder-and-voiding-dysfunction-in-female-taiwanese-residents-aged-40-years-and-above
#8
Soo-Cheen Ng, Suh-Woan Hu, Gin-Den Chen
OBJECTIVE: This is part of a three-year study designed to evaluate the natural history of lower urinary tract symptoms in local community residents aged 40 years and above in central Taiwan. We evaluated the prevalence of overactive bladder (OAB) and voiding dysfunction (VD) in female residents using validated questionnaires. MATERIALS AND METHODS: A structured questionnaire containing groups of different questionnaires was translated into Chinese and each one was validated separately...
December 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29224251/efficacy-and-safety-of-fesoterodine-treatment-for-overactive-bladder-symptoms-in-elderly-women-with-and-without-hypertension
#9
Osamu Yokoyama, Hidetomi Yamagami, Shintaro Hiro, Shinichi Hotta, Masaki Yoshida
OBJECTIVE: To assess fesoterodine treatment in elderly women with overactive bladder with and without hypertension. METHODS: Data for 2527 elderly women with overactive bladder symptoms, including urgency urinary incontinence, were pooled from 10 double-blind, placebo-controlled fesoterodine studies. RESULTS: A total of 1523 elderly women (60.3%) had a history of hypertension, and 1004 women (39.7%) had no hypertension history. Overactive bladder symptoms, mean bodyweight and mean body mass index at baseline were significantly higher in women with overactive bladder and hypertension versus those without hypertension (P < 0...
December 10, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29215517/two-year-results-of-burch-compared-with-midurethral-sling-with-sacrocolpopexy-a-randomized-controlled-trial
#10
Emanuel C Trabuco, Brian J Linder, Christopher J Klingele, Roberta E Blandon, John A Occhino, Amy L Weaver, Michaela E McGree, John B Gebhart
OBJECTIVE: To evaluate 1- and 2-year urinary continence rates after Burch retropubic urethropexy compared with a retropubic midurethral sling for women with urinary incontinence undergoing sacrocolpopexy. METHODS: We conducted a planned secondary analysis of a multicenter, randomized, single-blind trial comparing Burch with a sling that enrolled participants from June 2009 to August 2013. Objective outcome measures of continence were assessed at 1- and 2-year follow-up through office visits and validated questionnaires...
December 4, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29211399/oab-score-a-clinical-model-that-predicts-the-probability-of-presenting-overactive-detrusor-in-the-urodynamic-study
#11
Leandro Cristian Arribillaga, Marta Ledesma, Ariel Montedoro, Florencia Pisano, Rubén Guillermo Bengió
PURPOSE: To create a predictive model of involuntary detrusor contraction (IDC) to improve the diagnostic accuracy of overactive detrusor (OAD), associating overactive bladder (OAB) symptoms with other clinical parameters in the female population. MATERIALS AND METHODS: A total of 727 women were studied retrospectively. In all of them, urodynamic study was conducted for urogynecological causes. Demographics information, personal history, symptoms, physical exam, a 3-day frequency/volume chart and urinary culture, were collected in all patients and they subsequently underwent uroflowmetry and urodynamic studies...
December 7, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29205506/systematic-review-and-meta-analysis-on-the-efficacy-and-tolerability-of-mirabegron-for-the-treatment-of-storage-lower-urinary-tract-symptoms-overactive-bladder-comparison-with-placebo-and-tolterodine
#12
REVIEW
Arcangelo Sebastianelli, Giorgio I Russo, Steven A Kaplan, Kevin T McVary, Ignacio Moncada, Stavros Gravas, Christopher Chapple, Giuseppe Morgia, Sergio Serni, Mauro Gacci
A systematic review and meta-analysis was carried out to evaluate the efficacy and safety of mirabegron 50 mg and 100 mg in the treatment of storage lower urinary tract symptoms/overactive bladder in comparison with a placebo and tolterodine 4 mg. A total of 491 articles were collected and eight randomized studies were identified as eligible for this meta-analysis. Overall, eight trials were included in the meta-analysis evaluating 10 248 patients. Mirabegron at both doses of 50 mg and 100 mg, and and tolterodine 4 mg were significantly associated with the reduction of incontinence episodes per 24 h, reduction of mean number of micturitions per 24 h, increase of voided volume and reduction of urgency episodes per 24 h, compared to a placebo...
December 3, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29196071/percutaneous-tibial-nerve-stimulation-in-the-office-setting-real-world-experience-of-over-100-patients
#13
Evan R Sirls, Kim A Killinger, Judith A Boura, Kenneth M Peters
OBJECTIVE: To examine the outcomes and compliance with percutaneous tibial nerve stimulation (PTNS) for overactive bladder symptoms (OAB). METHODS: Adults that had PTNS from 6/30/2011 to 10/8/2015 were retrospectively reviewed for demographics, co-pay, travel distance, employment status, history, symptoms, and treatments used before, during and after PTNS. Pearson's Chi-square, Fisher's exact, Wilcoxon rank and paired t tests were performed. RESULTS: Of 113 patients (mean age 75 ± 12 years), most were women (65...
November 28, 2017: Urology
https://www.readbyqxmd.com/read/29175131/sacrocolpopexy-with-polyvinylidene-fluoride-mesh-for-pelvic-organ-prolapse-mid-term-comparative-outcomes-with-polypropylene-mesh
#14
Raffaele Balsamo, Ester Illiano, Alessandro Zucchi, Franca Natale, Antonio Carbone, Marco De Sio, Elisabetta Costantini
OBJECTIVE: The aim of this study was to compare the surgical, anatomical, and functional outcomes of sacrocolpopexy (SCP) using polyvinylidene fluoride (PVDF) mesh versus SCP using the standard polypropylene (PP) mesh. STUDY DESIGN: This was a retrospective single centre case-control study including female patients who underwent laparoscopic or abdominal SCP for POP with either PP (Cousin Biotech®) or PVDF (DynaMesh®-PRS) mesh between March 2005 and May 2015. Anatomical outcomes were assessed by the Pelvic Organ Prolapse Quantification (POP-Q) system...
November 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29153462/health-related-quality-of-life-and-toxicity-after-single-fraction-19%C3%A2-gy-high-dose-rate-prostate-brachytherapy-phase-ii-trial
#15
Alfonso Gomez-Iturriaga, Francisco Casquero, Jose Ignacio Pijoan, Pablo Minguez, Jose Maria Espinosa, Ana Irasarri, Andrea Bueso, Jon Cacicedo, David Buchser, Pedro Bilbao
PURPOSE: To evaluate the safety, tolerance and impact on health-related-quality-of-life (HRQoL) of the high-dose-rate brachytherapy of 19 Gy (BRT-HDR-19 Gy) single fraction in prostate cancer. METHODS: From January 2014 to July 2016, 43 patients with low/intermediate risk were treated with BRT-HDR-19 Gy. The patients were monitored prospectively for toxicity and HRQoL. RESULTS: The median age, initial PSA and the International Prostate Symptom Score (IPSS) were 71 years (55-78), 7...
November 15, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29151006/the-practical-update-for-family-physicians-in-the-diagnosis-and-management-of-overactive-bladder-and-lower-urinary-tract-symptoms
#16
Jack Barkin, Jeffrey Habert, Amy Wong, Livia Y T Lee
OBJECTIVE: To provide family physicians with an up-to-date, practical overview of the diagnosis and management of overactive bladder (OAB) alone or with bladder outlet obstruction. MAIN MESSAGE: OAB is urinary urgency with or without incontinence, often accompanied by frequency and nocturia, in the absence of urinary tract infection and can affect both men and women. Men often have co-existing OAB associated with bladder outlet obstruction, and benign prostatic hyperplasia...
October 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29144628/overactive-bladder-syndrome-and-bladder-wall-thickness-in-patients-with-obstructive-sleep-apnea-syndrome
#17
Zahide Yilmaz, Bekir Voyvoda, Pinar Bekdik Şirinocak
OBJECTIVE: The main objective of the present study was to evaluate the presence of overactive bladder (OAB) syndrome, nocturia, urgency, and urge incontinence in patients with obstructive sleep apnea syndrome (OSAS), and measure bladder wall thickness (BWT) in these patients. MATERIALS AND METHODS: The patient group was composed of 38 patients with OSAS. The control group was composed of 15 healthy individuals. All patients were evaluated using the Epworth Sleepiness Scale (ESS) and Overactive Bladder Symptom Score (OABSS)...
November 19, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29140559/comparative-efficacy-and-tolerability-of-solifenacin-5%C3%A2-mg-day-versus-other-oral-antimuscarinic-agents-in-overactive-bladder-a-systematic-literature-review-and-network-meta-analysis
#18
Jameel Nazir, Con Kelleher, Samuel Aballéa, Khaled Maman, Zalmai Hakimi, Colette Mankowski, Isaac Odeyemi
AIMS: To compare efficacy and tolerability of solifenacin 5 mg/day versus other oral antimuscarinic agents for the treatment of overactive bladder (OAB). METHODS: Literature searches of MEDLINE, Embase, and the Cochrane Library were undertaken to identify randomized controlled trials in OAB (2000-2015) for antimuscarinic agents. A network meta-analysis (NMA) was performed to estimate efficacy and tolerability outcomes for solifenacin 5 mg/day relative to other antimuscarinics...
November 15, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29139310/pudendal-nerve-injury-impairs-anorectal-function-and-health-related-quality-of-life-measures-%C3%A2-2-years-after-3d-conformal-radiotherapy-for-prostate-cancer
#19
Eng Eric Yeoh, Rochelle Botten, Addolorata Di Matteo, Marcus Tippett, Jonathon Hutton, Robert Fraser, Phillip G Dinning, David Wattchow
PURPOSE: To compare GI symptoms, measures of generic and disease specific health related quality of life (HRQoL), anorectal and pudendal nerve function and anal sphincter morphology between (i) patients ≥2 years after 3D conformal radiotherapy (3D-CRT)±high dose rate (HDR) brachytherapy for carcinoma of the prostate and aged matched patients before radiotherapy and (ii) symptomatic and asymptomatic patients ≥2 years after 3D-CRT ± HDR brachytherapy. MATERIAL AND METHODS: Methodology included: (i) modified LENT-SOMA scales for GI symptoms, (ii) EORTC QLQ-C30 and EORTC QLQ-PR25 questionnaires for generic and disease specific HRQoL, (iii) anorectal manometry and terminal motor latency for anorectal and pudendal nerve function and (iv) endorectal ultrasound for anal sphincter morphology...
November 15, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29111381/baseline-lower-urinary-tract-symptoms-in-patients-enrolled-in-the-symptoms-of-lower-urinary-tract-dysfunction-research-network-lurn-a-prospective-observational-cohort-study
#20
Anne P Cameron, Christina Lewicky-Gaupp, Abigail R Smith, Brian T Helfand, John L Gore, J Quentin Clemens, Claire C Yang, Nazema Y Siddiqui, H Henry Lai, James W Griffith, Victor P Andreev, Gang Liu, Kevin Weinfurt, Cindy L Amundsen, Catherine S Bradley, John W Kusek, Ziya Kirkali
PURPOSE: To describe and compare the frequency and type of lower urinary tract symptoms (LUTS) reported by men and women at the time they were recruited from urology and urogynecology clinics into the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) multi-center, prospective, observational cohort study. MATERIALS AND METHODS: Six research sites enrolled treatment-seeking men and women who reported any LUTS at a frequency more than "rarely" during the past month on the LUTS tool...
October 27, 2017: Journal of Urology
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