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Urgency urinary incontinence

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https://www.readbyqxmd.com/read/29151006/the-practical-update-for-family-physicians-in-the-diagnosis-and-management-of-overactive-bladder-and-lower-urinary-tract-symptoms
#1
Jack Barkin, Jeffrey Habert, Amy Wong, Livia Y T Lee
OBJECTIVE: To provide family physicians with an up-to-date, practical overview of the diagnosis and management of overactive bladder (OAB) alone or with bladder outlet obstruction. MAIN MESSAGE: OAB is urinary urgency with or without incontinence, often accompanied by frequency and nocturia, in the absence of urinary tract infection and can affect both men and women. Men often have co-existing OAB associated with bladder outlet obstruction, and benign prostatic hyperplasia...
October 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29144628/overactive-bladder-syndrome-and-bladder-wall-thickness-in-patients-with-obstructive-sleep-apnea-syndrome
#2
Zahide Yilmaz, Bekir Voyvoda, Pinar Bekdik Şirinocak
OBJECTIVE: The main objective of the present study was to evaluate the presence of overactive bladder (OAB) syndrome, nocturia, urgency, and urge incontinence in patients with obstructive sleep apnea syndrome (OSAS), and measure bladder wall thickness (BWT) in these patients. MATERIALS AND METHODS: The patient group was composed of 38 patients with OSAS. The control group was composed of 15 healthy individuals. All patients were evaluated using the Epworth Sleepiness Scale (ESS) and Overactive Bladder Symptom Score (OABSS)...
November 19, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29140559/comparative-efficacy-and-tolerability-of-solifenacin-5%C3%A2-mg-day-versus-other-oral-antimuscarinic-agents-in-overactive-bladder-a-systematic-literature-review-and-network-meta-analysis
#3
Jameel Nazir, Con Kelleher, Samuel Aballéa, Khaled Maman, Zalmai Hakimi, Colette Mankowski, Isaac Odeyemi
AIMS: To compare efficacy and tolerability of solifenacin 5 mg/day versus other oral antimuscarinic agents for the treatment of overactive bladder (OAB). METHODS: Literature searches of MEDLINE, Embase, and the Cochrane Library were undertaken to identify randomized controlled trials in OAB (2000-2015) for antimuscarinic agents. A network meta-analysis (NMA) was performed to estimate efficacy and tolerability outcomes for solifenacin 5 mg/day relative to other antimuscarinics...
November 15, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29139310/pudendal-nerve-injury-impairs-anorectal-function-and-health-related-quality-of-life-measures-%C3%A2-2-years-after-3d-conformal-radiotherapy-for-prostate-cancer
#4
Eng Eric Yeoh, Rochelle Botten, Addolorata Di Matteo, Marcus Tippett, Jonathon Hutton, Robert Fraser, Phillip G Dinning, David Wattchow
PURPOSE: To compare GI symptoms, measures of generic and disease specific health related quality of life (HRQoL), anorectal and pudendal nerve function and anal sphincter morphology between (i) patients ≥2 years after 3D conformal radiotherapy (3D-CRT)±high dose rate (HDR) brachytherapy for carcinoma of the prostate and aged matched patients before radiotherapy and (ii) symptomatic and asymptomatic patients ≥2 years after 3D-CRT ± HDR brachytherapy. MATERIAL AND METHODS: Methodology included: (i) modified LENT-SOMA scales for GI symptoms, (ii) EORTC QLQ-C30 and EORTC QLQ-PR25 questionnaires for generic and disease specific HRQoL, (iii) anorectal manometry and terminal motor latency for anorectal and pudendal nerve function and (iv) endorectal ultrasound for anal sphincter morphology...
November 15, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29111381/baseline-lower-urinary-tract-symptoms-in-patients-enrolled-in-the-symptoms-of-lower-urinary-tract-dysfunction-research-network-lurn-a-prospective-observational-cohort-study
#5
Anne P Cameron, Christina Lewicky-Gaupp, Abigail R Smith, Brian T Helfand, John L Gore, J Quentin Clemens, Claire C Yang, Nazema Y Siddiqui, H Henry Lai, James W Griffith, Victor P Andreev, Gang Liu, Kevin Weinfurt, Cindy L Amundsen, Catherine S Bradley, John W Kusek, Ziya Kirkali
PURPOSE: To describe and compare the frequency and type of lower urinary tract symptoms (LUTS) reported by men and women at the time they were recruited from urology and urogynecology clinics into the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) multi-center, prospective, observational cohort study. MATERIALS AND METHODS: Six research sites enrolled treatment-seeking men and women who reported any LUTS at a frequency more than "rarely" during the past month on the LUTS tool...
October 27, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29095509/urinary-incontinence-in-pregnant-adolescents-a-case-series
#6
Leila Barbosa, Thamiris Cruz, Amanda Carvalho, Elise Torres, Isabel Porto, Kaylla Nascimento, Andrea Lemos
AIMS: Determine the severity of urinary incontinence (UI) and its effect on the quality of life (QoL) of pregnant adolescents, as well as explore the strategies used to manage UI and the reporting/investigation of this condition by healthcare professionals. METHODS: A case series was conducted in three Brazilian public hospitals that offer prenatal care. Inclusion criteria were: age between 10 and 19 years, gestational age of 27 weeks or more, and reported UI in the third trimester of pregnancy...
November 2, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29076391/management-of-stress-urinary-incontinence-in-spinal-cord-injured-female-patients-with-a-mid-urethral-tape-a-single-center-experience
#7
Vasileios I Sakalis, Michael S Floyd, Philippa Caygill, Chloe Price, Ben Hartwell, Peter J Guy, Melissa C Davies
CONTEXT/OBJECTIVE: Stress urinary incontinence (SUI) affects the quality of life of females with spinal cord injury (SCI), has a negative impact on functional independence and disturbs their psychosocial interaction. Our aim was to assess the efficacy of mid-urethral tapes (MUT) in managing stress urinary incontinence in this population. DESIGN: Retrospective cohort study. PARTICIPANTS: SCI females with upper motor neuron lesion and urodynamically proven stress or mixed urinary incontinence that was treated with a mid-urethral tape and followed up for at least 12 months...
October 27, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29067433/urinary-incontinence-in-women-a-review
#8
REVIEW
Emily S Lukacz, Yahir Santiago-Lastra, Michael E Albo, Linda Brubaker
Importance: Urinary incontinence, the involuntary loss of urine, is a common health condition that may decrease quality of life. Ten to twenty percent of women and up to 77% of women residing in nursing homes have urinary incontinence, yet only 25% seek or receive treatment. Observations: This review summarizes the evaluation and therapeutic options for women affected by urinary incontinence. The initial assessment should focus on understanding the effect of incontinence on quality of life, the patient's goals and preferences for treatment, the results of previous treatments, and the presence of concomitant conditions, such as advanced pelvic organ prolapse, that may require referral...
October 24, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29044760/development-of-novel-and-non-invasive-diagnostic-markers-for-lower-urinary-tract-symptoms-using-urothelial-cells-in-voided-urine
#9
Hiroshi Shimura, Takahiko Mitsui, Sachiko Tsuchiya, Tatsuya Miyamoto, Tatsuya Ihara, Satoru Kira, Hiroshi Nakagomi, Norifumi Sawada, Yuki Imai, Takanori Mochizuki, Masayuki Takeda
OBJECTIVES: We evaluated the association between lower urinary tract symptoms (LUTS) and the expression of connexin (Cx) and transient receptor potential (TRP) channel on urothelial cells non-invasively collected from voided urine in humans. METHODS: A total of 55 patients (36 males and 19 females, median age: 71 years old), who were followed up at University of Yamanashi Hospital, were enrolled in the present study. Urothelial cells were collected from voided urine of patients, and the mRNA expression of each subtype of Cxs and TRP channels was measured using quantitive real-time reverse transcription polymerase chain reaction...
October 17, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29031894/refractory-urgency-urinary-incontinence-treatment-in-women-impact-of-age-on-outcomes-and-complications
#10
Yuko M Komesu, Cindy L Amundsen, Holly E Richter, Stephen W Erickson, Mary F Ackenbom, Uduak U Andy, Vivian W Sung, Michael Albo, W Thomas Gregory, Marie Fidela Paraiso, Dennis Wallace
BACKGROUND: Women with refractory urgency urinary incontinence (ie, unresponsive to behavioral and pharmacological interventions) are treated with onabotulinumtoxinA or sacral neuromodulation. OBJECTIVE: The objective of the study was to compare treatment efficacy and adverse events in women <65 and ≥65 years old treated with onabotulinumtoxinA or sacral neuromodulation. STUDY DESIGN: This study was a planned secondary analysis of a multicenter, randomized trial that enrolled community-dwelling women with refractory urgency urinary incontinence to onabotulinumtoxinA or sacral neuromodulation treatments...
October 12, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29024564/videourodynamic-factors-predictive-of-successful-onabotulinumtoxina-urethral-sphincter-injection-for-neurogenic-or-non-neurogenic-detrusor-underactivity
#11
Yuan-Hong Jiang, Jia-Fong Jhang, Sheng-Fu Chen, Hann-Chorng Kuo
OBJECTIVE: The aim of the present study was to analyze treatment outcomes and identify videourodynamic factors predictive of successful urethral onabotulinumtoxinA treatment of neurogenic and non-neurogenic detrusor underactivity (DU). METHODS: Patients with DU refractory to medical treatment were treated with injections totaling 100 U onabotulinumtoxinA into the urethral sphincter. Treatment outcomes were assessed 1 month after treatment using the Global Response Assessment...
October 11, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28988907/validity-of-utility-measures-for-women-with-pelvic-organ%C3%A2-prolapse
#12
Heidi S Harvie, Daniel D Lee, Uduak U Andy, Judy A Shea, Lily A Arya
BACKGROUND: Pelvic organ prolapse is a common condition that frequently coexists with urinary and fecal incontinence. The impact of prolapse on quality of life is typically measured through condition-specific quality-of-life instruments. Utility preference scores are a standardized generic health-related quality-of-life measure that summarizes morbidity on a scale from 0 (death) to 1 (optimum health). Utility preference scores quantify disease severity and burden and are widely used in cost-effectiveness research...
October 6, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28975365/effects-of-urine-alkalinization-with-sodium-bicarbonate-orally-on-lower-urinary-tract-symptoms-in-female-patients-a-pilot-study
#13
Mehmet Giray Sönmez, Yunus Emre Göğer, Gökhan Ecer, Ahmet Atıcı, Mehmet Serkan Özkent, Ahmet Öztürk
INTRODUCTION AND HYPOTHESIS: In this study, we planned to explore the effects of sodium bicarbonate orally (NaHCO3) treatment on female patients with lower urinary tract symptoms (LUTS) who have acidic urine pH values (<6). METHODS: NaHCO3 was given orally to 33 female patients for 4 weeks at a dose of 2 × 4 g/day. Laboratory values, bladder diary, the Patient Perception of Bladder Condition Score (PPBC), Patient Perception of Intensity of Urgency Scale (PPIUS), Overactive Bladder-Validated 8-question Awareness tool (OAB-V8), Pelvic Pain and Urgency & Frequency Patient Symptom Scale tests (PUFSS), and the King's Health Questionnaire (KHQ) scores before and after treatment were compared...
October 3, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28974365/predictors-of-outcome-in-children-and-adolescents-with-overactive-bladder-treated-with-parasacral-transcutaneous-electrical-nerve-stimulation
#14
Anselmo Hoffmann, Clara Sampaio, Ana Aparecida Nascimento, Maria Luiza Veiga, Ubirajara Barroso
BACKGROUND: Parasacral transcutaneous electrical nerve stimulation (TENS) has emerged as an effective treatment for overactive bladder (OAB) in view of its high success rates in improving lower urinary tract symptoms and constipation, with no direct side effects. However, the clinical characteristics associated with the outcomes remain to be established. OBJECTIVE: The aim of this study was to evaluate potential predictors of outcome in children with OAB treated using parasacral TENS...
September 8, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28970803/high-frequency-stimulation-of-the-pelvic-nerve-inhibits-urinary-voiding-in-anesthetized-rats
#15
Jonathan J Crook, Thelma A Lovick
Urge Urinary Incontinence: "a sudden and uncontrollable desire to void which is impossible to defer" is extremely common and considered the most bothersome of lower urinary tract conditions. Current treatments rely on pharmacological, neuromodulatory, and neurotoxicological approaches to manage the disorder, by reducing the excitability of the bladder muscle. However, some patients remain refractory to treatment. An alternative approach would be to temporarily suppress activity of the micturition control circuitry at the time of need i...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28965358/benefits-and-limitations-of-animal-models-in-partial-bladder-outlet-obstruction-for-translational-research
#16
REVIEW
Takeya Kitta, Yukiko Kanno, Hiroki Chiba, Madoka Higuchi, Mifuka Ouchi, Mio Togo, Kimihiko Moriya, Nobuo Shinohara
The functions of the lower urinary tract have been investigated for more than a century. Lower urinary tract symptoms, such as incomplete bladder emptying, weak urine stream, daytime urinary frequency, urgency, urge incontinence and nocturia after partial bladder outlet obstruction, is a frequent cause of benign prostatic hyperplasia in aging men. However, the pathophysiological mechanisms have not been fully elucidated. The use of animal models is absolutely imperative for understanding the pathophysiological processes involved in bladder dysfunction...
October 1, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28954462/is-there-any-difference-between-depression-and-anxiety-in-overactive-bladder-according-to-sex-a-systematic-review-and-meta-analysis
#17
Iane Glauce R Melotti, Cássia Raquel Teatin Juliato, Suelene Costa de Albuquerque Coelho, Marcelo Lima, Cassio Luiz Zanettini Riccetto
PURPOSE: Overactive bladder (OAB) is characterized by urinary urgency with or without urge incontinence, accompanied by frequency and nocturia. It affects individuals of all ages and can predispose affected individuals to depression and anxiety. However, few studies have been conducted on this topic. The objective of this study was to perform a systematic review and meta-analysis assessing the symptoms of depression, anxiety, and OAB using validated instruments. METHODS: The search for articles was based on the following descriptors: overactive bladder, depression, and anxiety ("Urinary bladder, Overactive AND Depression and Anxiety") OR ("Urinary bladder, Overactive AND Depression" OR "Urinary bladder, Overactive AND Anxiety")...
September 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28953078/inflammatory-urinary-cytokine-expression-and-quality-of-life-in-patients-with-overactive-bladder
#18
Nirmala Pillalamarri, Dara F Shalom, Marjorie L Pilkinton, Harvey A Winkler, Prodyot K Chatterjee, Malvika Solanki, Christine N Metz
OBJECTIVE: The aims of this study were to analyze levels of selected inflammatory urinary cytokines/chemokines in subjects with overactive bladder (OAB) and to determine if cytokine/chemokine levels correlate with quality of life and symptom distress. METHODS: This prospective, case-control pilot analysis included 23 women with OAB and 22 control subjects. Overactive bladder subjects were enrolled if they had symptoms of urinary frequency, urgency, or urge incontinence for more than 3 months and urodynamic evidence of detrusor overactivity...
September 25, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28948486/efficacy-and-tolerability-of-phytomedicines-in-multiple-sclerosis-patients-a-review
#19
REVIEW
Mohammad Hosein Farzaei, Zahra Shahpiri, Roodabeh Bahramsoltani, Marjan Moghaddam Nia, Fariba Najafi, Roja Rahimi
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disorder of the central nervous system (CNS) that can cause cognition, mobility, and sensory impairments. It is considered one of the most common non-traumatic causes of disability in the world. The aim of the present article was to review the clinical evidence related to medicinal plants in the management of MS symptoms. Electronic databases, including the Cochrane Library, Pubmed, and Scopus, were searched for entries from 1966 to February 2017...
October 2017: CNS Drugs
https://www.readbyqxmd.com/read/28941138/prolapse-surgery-with-or-without-incontinence-procedure-a-systematic-review-and-meta-analysis
#20
REVIEW
J Marinus van der Ploeg, Annemarie van der Steen, Sandra Zwolsman, C Huub van der Vaart, Jan-Paul W R Roovers
BACKGROUND: To reduce the risk of postoperative stress urinary incontinence (POSUI) prolapse repair might be combined with incontinence surgery. OBJECTIVES: Compare efficacy and safety of prolapse surgery with and without incontinence surgery. SEARCH STRATEGY: Including our earlier review a systematic search in PubMed, EMBASE, the Cochrane Library and the Register of Current Controlled Trials was performed from 1995 to 2017. SELECTION CRITERIA: Randomised trials comparing prolapse surgery with a midurethral sling (MUS) or Burch colposuspension...
September 22, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
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