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Gadolinium sella

Afif Nakhleh, Leonard Saiegh, Maria Reut, Mohammad Sheikh Ahmad, Irit Wirsansky Pearl, Carmela Shechner
OBJECTIVE: Cushing's disease during pregnancy is associated with an increased risk for maternal and fetal complications. In recurrent Cushing`s disease following transsphenoidal surgery, and when re-operation is not feasible, medical treatment is usually considered. Cabergoline was found to be effective in reducing hypercortisolism in Cushing's disease. Evolving data concerning the safety of cabergoline use during pregnancy show no significant increase in the rate of complications during pregnancy or the postnatal period...
July 2016: Hormones: International Journal of Endocrinology and Metabolism
Lijun Sun, Yan Zhu, Hong Wang
Three cases of intracranial angioleiomyoma (ALM) in our neurosurgery center are reported in detail. ALM is a benign soft tissue tumor comprised of mature smooth muscle cells and a prominent vascular component, which is extremely rare as a primary intracranial lesion. Altogether, only 12 cases were recorded in the literature to date, to the best of our knowledge. Case 1 is the second report of intra-sella ALM, a 51-year-old woman presented with visual deterioration for 2 months. An MRI showed an intra-sella 3-cm tumor, partially flame-like, enhanced with gadolinium...
2014: World Journal of Surgical Oncology
Kiyoharu Shimizu, Atsushi Tominaga, Yasuyuki Kinoshita, Satoshi Usui, Kazuhiko Sugiyama, Kaoru Kurisu
A 64-year-old male presented with an incidental tumor in the sella turcica during a brain medical checkup. Because he lacked any neurological symptoms or signs of pituitary dysfunction, the patient did not undergo surgery. Three years later, visual disturbances developed, including poor eyesight and visual field defects. The response to the growth hormone(GH)releasing peptide-2 demonstrated severe GH deficiency. MRI revealed an enlarged tumor appearing as a mosaic pattern of high and very low intensity on T2-weighted imaging...
October 2013: No Shinkei Geka. Neurological Surgery
Ratchaneewan Kwancharoen, Ari M Blitz, Fabiana Tavares, Patrizio Caturegli, Gary L Gallia, Roberto Salvatori
Meningiomas account for about 1% of sellar masses. Although they can mimic pituitary adenomas, they are more vascularized and invasive. To gain insights that would enhance our ability to establish a pre-surgical diagnosis of meningioma, we performed a retrospective study of these tumors. Query of the surgical pathology database identified 1,516 meningiomas operated at out institution between January 2000 and May 2012. Cases were matched to the radiology database to identify a strictly defined sellar and/or suprasellar location...
August 2014: Pituitary
Adrienne M Laury, Nelson M Oyesiku, Costas G Hadjipanayis, John M Delgaudio, Sarah K Wise
BACKGROUND: The endoscopic transsphenoidal approach (eTSA) to lesions of the sellar region is typically performed jointly by neurosurgeons and otolaryngologists. Occasionally, the approach is significantly altered by sinonasal disease, anatomic variants, or previous surgery. However, there are no current guidelines that describe which physical or radiological findings should prompt a change in the plan of care. The purpose of this study was to determine the incidence of sinonasal pathology or anatomic variants noted endoscopically or by imaging that altered preoperative or intraoperative management...
May 2013: American Journal of Rhinology & Allergy
L Lachhab, M Fikri, E H Aitbenhaddou, Y Arkha, W Regragui, M Jiddane, A Benomar, M Yahyaoui
Lung carcinomas have a high propensity to metastasize to the liver, adrenal, bone or brain. However, certain atypical intracranial sites may occur. We report two cases of adenocarcinoma of the lung discovered by peculiar brain metastases. The first patient presented with an orbital apex syndrome due to a metastasis to the cavernous sinus with intraorbital extension. The second patient presented with headache and visual loss due to metastasis to the pituitary. Intrasellar and parasellar metastases are rare sequelae of pulmonary neoplasms...
February 2013: Journal Français D'ophtalmologie
Pablo Ajler, Damián Bendersky, Santiago Hem, Alvaro Campero
BACKGROUND: Pituitary adenomas are a common cause of endocrinal dysfunction, which comprise 10-20% of all intracranial tumors. Although almost all of them arise within the sella turcica, there are some rare cases in which a pituitary adenoma is located outside the intrasellar region, so it is defined as an ectopic pituitary adenoma (EPA). CASE DESCRIPTION: We described a case of a 31-year-old male with a serum prolactin (PRL) value of 240 ng/ml Magnetic resonance imaging (MRI) showed a space-occupying mass within the sphenoid sinus (SS) which partially enhanced by gadolinium...
2012: Surgical Neurology International
Han Bee Lee, Sung Tae Kim, Hyung-Jin Kim, Keon Ha Kim, Pyoung Jeon, Hong Sik Byun, Jin Wook Choi
OBJECTIVE: Does dynamic gadolinium-enhanced imaging with simultaneous acquisition of coronal and sagittal planes improve diagnostic accuracy of pituitary microadenomas compared with coronal images alone? METHODS: Fifty-six patients underwent 3-T sella MRI including dynamic simultaneous acquisition of coronal and sagittal planes after gadolinium injection. According to conspicuity, lesions were divided into four scores (0, no; 1, possible; 2, probable; 3, definite delayed enhancing lesion)...
March 2012: European Radiology
G I Ogbole, O A Adeyinka, C A Okolo, A O Ogun, O M Atalabi
BACKGROUND: Magnetic resonance imaging (MRI), an advancement which followed computed tomography (CT) is expensive and inaccessible in most developing countries. However it is the procedure of choice in evaluating sellar and parasellar lesions. Its major advantages are its superior soft tissue contrast differentiation, its capacity for multiplanar imaging and nonexistence of ionising radiation. Its use is relatively new in Nigeria, a developing economy in Africa. Since its introduction in 2005, it has been utilised extensively for neuroimaging at the University College Hospital (UCH), Ibadan; a large hospital in south-western Nigeria...
February 2012: European Journal of Radiology
Liu-Guan Bian, Qing-Fang Sun, Hua-Cheng Wu, Hong Jiang, Yue-Hao Sun, Jian-Kang Shen
Choroid plexus papillomas are rare tumors of the central nervous system and are usually confined to the ventricular system. We illustrated a primary choroid plexus papilloma in the pituitary fossa. A 31-year-old female presented with amenorrhea and intermittent galactorrhoea, with no visual complaints in the last 2 years. Endocrine testing showed no hormone excess or deficiency of the pituitary and target glands, except for a higher prolactin level (56 ng/ml). A sharply circumscribed regular mass in the sellar region occupying the entire sella turcica and extending into the suprasellar cistern was demonstrated on MR imaging with gadolinium diethylenetriamine pentaacetic acid...
April 2011: Acta Neurochirurgica
C Parlato, G di Nuzzo, M Luongo, F Tortora, F Briganti
We report on one case of variant origin of right ophthalmic artery (OA) from C4 choroidal segment of the right supraclinoid internal carotid artery. A 41-year-old woman affected by bitemporal hemianopsia performed Magnetic Resonance Imaging with gadolinium showing tuberculum sellae meningioma. During angiography we observed this variant of origin of OA. At surgical dissection, we observed this variant in carotid cistern.
April 2011: Surgical and Radiologic Anatomy: SRA
Azmy M Hadidy, Dana G Jallad, Azmi A Haroun, Waleed S Mahafza, Kamel M Ajlouni
OBJECTIVE: To assess the pituitary findings as demonstrated on MRI and to compare the results with the data published in the literature. METHODS: One thousand, one hundred and thirty-eight pituitary MRI`s with and without intravenous contrast media (gadolinium) were performed over 6 years from 2001 to 2007 in the Department of Diagnostic Radiology, Jordan University Hospital, Amman, Jordan. The patients were referred from various departments and were evaluated for pituitary, other sellar, and juxtasellar abnormalities...
April 2009: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
Jerrold L Boxerman, Jeffrey M Rogg, John E Donahue, Jason T Machan, Marc A Goldman, Curt E Doberstein
OBJECTIVE: The purpose of this study was to determine whether the preoperative MRI findings of enhanced diffusivity, macrocyst content, and internal hemorrhage in pituitary macroadenomas are predictive of successful transsphenoidal hypophysectomy. MATERIALS AND METHODS: We retrospectively reviewed the preoperative and postoperative sella protocol MR images of 28 patients who underwent transsphenoidal hypophysectomy for chiasm-compressing macroadenoma. Chiasmatic decompression defined surgical success...
September 2010: AJR. American Journal of Roentgenology
Jean-François Vendrell, Denis Hoa, Gerald Gahide
No abstract text is available yet for this article.
May 1, 2010: Lancet
F Lamazou, S Ouzounian, C Dupas, S Christin-Maitre
We report the case of a 21-year-old pregnant women (36 WA) presenting intensive headaches and visual disturbances. Those sellar compression symptoms have made us suppose the diagnosis of autoimmune hypophysitis. MRI has confirmed the typical aspect of symmetric enlargement of the pituitary gland with a strong and homogenous enhancement after gadolinium. This pathology associated to a high morbidity and mortality due to partial or complete deficit of the anterior pituitary hormones, shall be reminded more often...
April 2010: Gynécologie, Obstétrique & Fertilité
Suguru Kakite, Shinya Fujii, Masamichi Kurosaki, Yoshiko Kanasaki, Eiji Matsusue, Toshio Kaminou, Toshihide Ogawa
INTRODUCTION: To clarify whether a three-dimensional-gradient echo (3D-GRE) or spin echo (SE) sequence is more useful for evaluating sellar lesions on contrast-enhanced T1-weighted MR imaging at 3.0Tesla (T). METHODS: We retrospectively assessed contrast-enhanced T1-weighted images using 3D-GRE and SE sequences at 3.0T obtained from 33 consecutive patients with clinically suspected sellar lesions. Two experienced neuroradiologists evaluated the images qualitatively in terms of the following criteria: boundary edge of the cavernous sinus and pituitary gland, border of sellar lesions, delineation of the optic nerve and cranial nerves within the cavernous sinus, susceptibility and flow artifacts, and overall image quality...
July 2011: European Journal of Radiology
Ruth Eliahou, Tamar Sella, Tanir Allweis, Yaacov Samet, Eugene Libson, Miri Sklair-Levy
BACKGROUND: Magnetic resonance imaging of the breast has emerged as a valuable imaging tool in addition to conventional imaging modalities. It has high sensitivity for malignant lesions and can detect mammographically, sonographically and clinically occult cancers. "MR only" lesions are best biopsied under MR guidance; however, this may be a challenging task. OBJECTIVES: To evaluate our initial clinical experience with MR-guided core needle breast biopsy and MR-guided needle localization...
May 2009: Israel Medical Association Journal: IMAJ
Hyun-Woong Park, Shin Jung, Tae-Young Jung, Kyung-Sub Moon
A 49-year-old woman presented with headache, vomiting and visual disturbance. Neurological examination revealed bitemporal hemianopsia with poor visual acuity. Magnetic resonance imaging showed a bulky intra-suprasellar mass, which was isointense with brain parenchyma on T1-weighted images, and slightly hyperintense on T2-weighted images. After gadolinium administration, the mass was homogeneously enhanced. The mass was partially removed by the endonasal transsphenoidal approach and then the remnant mass was totally removed by the transcranial approach five months later...
June 2009: Journal of Korean Neurosurgical Society
Sei Sugata, Hirofumi Hirano, Kazutaka Yatsushiro, Shunji Yunoue, Katsumi Nakamura, Kazunori Arita
A 26-year-old man presented with a xanthogranuloma located exclusively in the suprasellar region manifesting as general fatigue, bitemporal hemianopsia, and polyuria. Endocrinological examination disclosed severe hypopituitarism. Magnetic resonance imaging demonstrated a clearly defined suprasellar mass that was heterogeneously enhanced after gadolinium administration and was markedly hypointense on T(2)-weighted images. The tumor was subtotally removed under a preoperative diagnosis of craniopharyngioma. Histological examination found fibrous tissue with abundant cholesterol clefts, multinucleated giant cells, and hemosiderin deposits, but no epithelial cells...
March 2009: Neurologia Medico-chirurgica
R Forghani, R I Farb
INTRODUCTION: A comprehensive evaluation of cranial magnetic resonance imagings (MRIs) of 23 patients with intracranial hypotension (IH) was performed, and the evolution of the abnormalities on follow-up MRIs was correlated with the clinical outcome. MATERIALS AND METHODS: The MRI report database at the University Health Network in Toronto was searched, and 23 cases of IH were identified between 2001 and 2007. A retrospective review of the MRIs of the brain and the electronic patient chart was performed...
December 2008: Neuroradiology
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